Page last updated: 2024-09-03

benzyloxycarbonylarginyl-arginine 4-methylcoumarin-7-ylamide and warfarin

benzyloxycarbonylarginyl-arginine 4-methylcoumarin-7-ylamide has been researched along with warfarin in 13 studies

Compound Research Comparison

Studies
(benzyloxycarbonylarginyl-arginine 4-methylcoumarin-7-ylamide)
Trials
(benzyloxycarbonylarginyl-arginine 4-methylcoumarin-7-ylamide)
Recent Studies (post-2010)
(benzyloxycarbonylarginyl-arginine 4-methylcoumarin-7-ylamide)
Studies
(warfarin)
Trials
(warfarin)
Recent Studies (post-2010) (warfarin)
140136,5732,14314,728

Protein Interaction Comparison

ProteinTaxonomybenzyloxycarbonylarginyl-arginine 4-methylcoumarin-7-ylamide (IC50)warfarin (IC50)
Vitamin K epoxide reductase complex subunit 1 Homo sapiens (human)0.0088

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (61.54)18.2507
2000's4 (30.77)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lima, AP; Ménard, R; Scharfstein, J; Storer, AC1
Dengler, R; Emmerich, B; Fritz, H; Gabrijelcic, D; Lah, T; Turk, V1
Hasnain, S; Hirama, T; Khouri, HE; Ménard, R; Plouffe, C; Storer, AC1
Khalfan, HA1
Halton, DW; McGinty, A; Moore, M; Walker, B1
Götz, B; Klinkert, MQ1
Aisa, MC; Maggio, D; Rahman, S; Russell, RG; Senin, U1
Ghoneim, H; Klinkert, MQ1
Doi, Y; Ichishima, E; Kawabata, C1
Monsour, PA; Smid, JR; Young, WG1
Fujiwara, R; Hotez, PJ; Loukas, A; Mulvenna, J; Ranjit, N; Stenzel, DJ; Zhan, B1
Kongkerd, N; McKerrow, JH; Morakote, N; Sajid, M; Uparanukraw, P1
Allanki, AD; Deshmukh, MV; Kolla, VK; Navale, R; Prasad, R; Sayyad, Z; Shah, AY; Sijwali, PS; Singhal, N; Sudhakar, R; Tanneru, N; Venkatesan, V1

Other Studies

13 other study(ies) available for benzyloxycarbonylarginyl-arginine 4-methylcoumarin-7-ylamide and warfarin

ArticleYear
Temperature-dependent substrate inhibition of the cysteine proteinase (GP57/51) from Trypanosoma cruzi.
    Molecular and biochemical parasitology, 1992, Volume: 56, Issue:2

    Topics: Animals; Antigens, Protozoan; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Dose-Response Relationship, Drug; Glycoproteins; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Trypanosoma cruzi

1992
Detection of cathepsin B in tumor cytosol and urine of breast cancer patients.
    Biomedica biochimica acta, 1991, Volume: 50, Issue:4-6

    Topics: Adult; Aged; Breast Neoplasms; Cathepsin B; Coumarins; Cytosol; Dipeptides; Female; Fluorescent Dyes; Humans; Middle Aged; Substrate Specificity

1991
A model to explain the pH-dependent specificity of cathepsin B-catalysed hydrolyses.
    The Biochemical journal, 1991, May-01, Volume: 275 ( Pt 3)

    Topics: Cathepsin B; Coumarins; Dipeptides; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Liver; Substrate Specificity

1991
Study of thiol proteases of normal human skin fibroblasts.
    Cell biochemistry and function, 1991, Volume: 9, Issue:1

    Topics: Caseins; Cathepsin B; Cathepsin H; Cathepsin L; Cathepsins; Cell Fractionation; Cells, Cultured; Concanavalin A; Coumarins; Cysteine Endopeptidases; Dipeptides; Endopeptidases; Fibroblasts; Humans; Hydrogen-Ion Concentration; Hymecromone; Leupeptins; Lysosomes; Microsomes; Skin

1991
Characterization of the cysteine proteinases of the common liver fluke Fasciola hepatica using novel, active-site directed affinity labels.
    Parasitology, 1993, Volume: 106 ( Pt 5)

    Topics: Affinity Labels; Animals; Biotin; Coumarins; Culture Media; Cysteine Endopeptidases; Diazomethane; Dipeptides; Fasciola hepatica; Fluorescent Dyes; Hydrogen-Ion Concentration; Hydrolysis; Molecular Weight; Oligopeptides; Spectrometry, Fluorescence; Substrate Specificity

1993
Expression and partial characterization of a cathepsin B-like enzyme (Sm31) and a proposed 'haemoglobinase' (Sm32) from Schistosoma mansoni.
    The Biochemical journal, 1993, Mar-15, Volume: 290 ( Pt 3)

    Topics: Amino Acid Sequence; Animals; Antigens, Helminth; Baculoviridae; Binding Sites; Cathepsin B; Cell Line; Cloning, Molecular; Coumarins; Cysteine Endopeptidases; Dipeptides; Gene Expression; Helminth Proteins; Hemoglobins; Hydrolysis; Immunoblotting; Molecular Sequence Data; Moths; Recombinant Proteins; Schistosoma mansoni; Substrate Specificity; Transfection

1993
Cathepsin B activity in normal human osteoblast-like cells and human osteoblastic osteosarcoma cells (MG-63): regulation by interleukin-1 beta and parathyroid hormone.
    Biochimica et biophysica acta, 1996, May-21, Volume: 1290, Issue:1

    Topics: Cathepsin B; Coumarins; Dipeptides; Enzyme Activation; Enzyme Stability; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Interleukin-1; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Tumor Cells, Cultured

1996
Biochemical properties of purified cathepsin B from Schistosoma mansoni.
    International journal for parasitology, 1995, Volume: 25, Issue:12

    Topics: Amino Acid Sequence; Animals; Cathepsin B; Coumarins; Dipeptides; Globins; Hydrogen-Ion Concentration; Immunochemistry; Molecular Sequence Data; Oligopeptides; Schistosoma mansoni; Substrate Specificity

1995
Miltpain, a cysteine proteinase, from milt of Pacific cod (Gadus macrocephalus): purification and characterization.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2000, Volume: 125, Issue:4

    Topics: Amino Acid Sequence; Animals; Coumarins; Cysteine Endopeptidases; Dipeptides; Enzyme Activation; Enzyme Inhibitors; Fishes; Hydrogen-Ion Concentration; Isoelectric Point; Molecular Sequence Data; Substrate Specificity

2000
Dipeptidyl-peptidase II and cathepsin B activities in amelogenesis of the rat incisor.
    European journal of oral sciences, 2001, Volume: 109, Issue:4

    Topics: Amelogenesis; Amelogenin; Animals; Blotting, Western; Cathepsin B; Chromogenic Compounds; Coumarins; Dental Enamel Proteins; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Electrophoresis, Polyacrylamide Gel; Enamel Organ; Fluorescent Dyes; Hydrogen-Ion Concentration; Immunoblotting; Incisor; Kidney; Lysosomes; Rats; Rats, Wistar; Spectrometry, Fluorescence; Statistics as Topic

2001
A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus.
    Molecular and biochemical parasitology, 2008, Volume: 160, Issue:2

    Topics: Amino Acid Sequence; Animals; Cathepsin B; Cloning, Molecular; Coumarins; Cricetinae; Dipeptides; Escherichia coli; Gelatin; Gene Expression; Gene Expression Profiling; Haemonchus; Hemoglobins; Mice; Molecular Sequence Data; Necator americanus; Phylogeny; Pichia; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Up-Regulation

2008
Identification and characterization of a cathepsin L-like cysteine protease from Gnathostoma spinigerum.
    Molecular and biochemical parasitology, 2008, Volume: 160, Issue:2

    Topics: Amino Acid Sequence; Animals; Base Sequence; Caenorhabditis elegans; Cathepsin L; Cathepsins; Cloning, Molecular; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Gene Expression; Gene Library; Gnathostoma; Humans; Molecular Sequence Data; Molecular Weight; Open Reading Frames; Phylogeny; Pichia; Protein Sorting Signals; Protein Structure, Tertiary; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Substrate Specificity

2008
Independent amino acid residues in the S2 pocket of falcipain-3 determine its specificity for P2 residues in substrates.
    Molecular and biochemical parasitology, 2015, Volume: 202, Issue:2

    Topics: Amino Acid Sequence; Catalytic Domain; Cathepsin L; Coumarins; Cysteine Endopeptidases; Dipeptides; Hemoglobins; Humans; Hydrogen-Ion Concentration; Hydrolysis; Leucine; Malaria, Falciparum; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Plasmodium falciparum; Protozoan Proteins; Substrate Specificity

2015