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benzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide and warfarin

benzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide has been researched along with warfarin in 48 studies

Compound Research Comparison

Studies
(benzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide)
Trials
(benzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide)
Recent Studies (post-2010)
(benzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide)
Studies
(warfarin)
Trials
(warfarin)
Recent Studies (post-2010) (warfarin)
480636,5732,14314,728

Protein Interaction Comparison

ProteinTaxonomybenzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide (IC50)warfarin (IC50)
Vitamin K epoxide reductase complex subunit 1 Homo sapiens (human)0.0088

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199010 (20.83)18.7374
1990's22 (45.83)18.2507
2000's9 (18.75)29.6817
2010's7 (14.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ando, M; Ishibashi, S; Ishii, K; Kato, K; Nishimura, Y; Okazaki, H; Tani, C1
Lima, AP; Ménard, R; Scharfstein, J; Storer, AC1
Balduyck, M; Degand, P; Demeyer, D; Duquesnoy, B; Flipo, RM; Huet, G; Richet, C; Thiebaut, C1
Ashall, F; Drake, L; Enahoro, H; Greig, S; Healy, N; Roberts, H; Shaw, E1
Ishiura, S; Kominami, E; Kumagai, N; Nishina, H; Sugita, H; Tanabe, H; Tsukahara, T1
Hasnain, S; Hirama, T; Khouri, HE; Ménard, R; Plouffe, C; Storer, AC1
Khalfan, HA1
Beynon, RJ; Bond, JS; Macadam, GC1
Paskhina, TS; Pozdnev, VF; Rabinovich, SE1
Mason, RW1
Cardozo, C; Galicki, N; Gariola, CG; Lesser, M1
Baricos, WH; Barrett, AJ; Mason, RW; Zhou, Y1
Ito, M; Katunuma, N; Kominami, E; Kuroda, Y; Miyao, M; Naito, E; Takeda, E; Toshima, K1
Gal, S; Gottesman, MM; Mason, RW1
Fuchiwaki, T; Furuya, H; Ishiura, S; Nojima, M; Okuyama, T; Sugita, H1
Sakata, M; Takamiya, O; Yoshikawa, I1
Barrett, AJ; Buttle, DJ; Nicklin, MJ; Zucker, S1
Deelder, AM; Dresden, MH; Koper, G; Ploem, JS; Rotmans, JP1
Barrett, AJ1
Dufour, E; Ménard, R; Storer, AC1
Cho, SY; Chung, YB; Joo, IJ; Kang, SY; Kong, Y1
Grab, DJ; Lonsdale-Eccles, JD; Mpimbaza, GW; Nkhungulu, ZR; Olobo, J; Smith, L; Tosomba, OM1
Rosenthal, PJ1
Brindley, PJ; Dalton, JP; Dowd, AJ; Loukas, AC; Prociv, P1
Lee, TC; Yih, LH1
Halton, DW; McGinty, A; Moore, M; Walker, B1
Ghoneim, H; Klinkert, MQ1
Chen, Y; Ménard, R; Plouffe, C; Storer, AC1
Illy, C; Mort, JS; Purisima, E; Quraishi, O; Vernet, T; Wang, J1
Coetzer, TH; Lonsdale-Eccles, JD; Pike, RN; Troeberg, L1
Fierlbeck, G; Mayer, P; Schaber, B; Schmid, H1
Brun, KA; D'alessio, KJ; Debouck, CM; McQueney, MS; Orsini, MJ1
Ascenzi, P; Bolognesi, M; Gradoni, L; Mattu, M; Polticelli, F; Salvati, L; Tiberi, F; Venturini, G1
Boll-Bataillé, E; Cotton, J; Ferrer-Di Martino, M; Gauthier, F; Lalmanach, G; Lecaille, F; McKerrow, JH1
Lechner, M; Merschak, P; Redl, B; van't Hof, W; Wojnar, P1
Ascenzi, P; Bocedi, A; Gradoni, L; Menegatti, E1
Lima, AP; Machado, EA; Oliveira, DM; Ramos, IB; Reis, FC1
Fujiwara, R; Hotez, PJ; Loukas, A; Mulvenna, J; Ranjit, N; Stenzel, DJ; Zhan, B1
Kongkerd, N; McKerrow, JH; Morakote, N; Sajid, M; Uparanukraw, P1
Ittiprasert, W; Knight, M; Miller, A; Myers, J; Raghavan, N1
Aor, AC; Branquinha, MH; d'Avila-Levy, CM; Elias, CG; Santos, AL; Valle, RS1
Deshapriya, RM; Kageyama, T; Usui, M; Yamamoto, Y; Yuhashi, S1
Dohmae, N; Isobe, T; Kubota, K; Nishii, W; Shibata, C; Suzuki, T; Takahashi, K1
Carlini, CR; Defferrari, MS; Demartini, DR; Marcelino, TB; Pinto, PM1
Barros, N; Breschi, L; Carmona, AK; Carrilho, MR; Gesteira, TF; Nascimento, FD; Pashley, DH; Scaffa, PM; Tersariol, IL; Tjäderhane, L; Vidal, CM1
Baici, A; Lenarčič, B; Novinec, M1
Ito, Y; Iwamoto, K; Tsuji, A; Tsukamoto, K; Yuasa, K1
Barbarin-Costes, F; Gehrcke, JP; Lalmanach, G; Lecaille, F; Livache, T; Mallèvre, F; Nizard, C; Perrier, E; Pisabarro, MT; Roget, A; Sage, J; Samsonov, SA; Schnebert, S1

Other Studies

48 other study(ies) available for benzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide and warfarin

ArticleYear
Possible involvement of cathepsin L in processing of rat liver hexokinase to eliminate mitochondria-binding ability.
    Journal of biochemistry, 1992, Volume: 112, Issue:3

    Topics: Animals; Binding Sites; Cathepsin L; Cathepsins; Coumarins; Cysteine Endopeptidases; Dipeptides; Endopeptidases; Fluorescent Dyes; Hexokinase; In Vitro Techniques; Kinetics; Liver; Mitochondria, Liver; Molecular Weight; Protein Processing, Post-Translational; Rats; Substrate Specificity

1992
Temperature-dependent substrate inhibition of the cysteine proteinase (GP57/51) from Trypanosoma cruzi.
    Molecular and biochemical parasitology, 1992, Volume: 56, Issue:2

    Topics: Animals; Antigens, Protozoan; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Dose-Response Relationship, Drug; Glycoproteins; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Trypanosoma cruzi

1992
Measurement of elastase and cysteine proteinases in synovial fluid of patients with rheumatoid arthritis, sero-negative spondylarthropathies, and osteoarthritis.
    Clinical chemistry, 1992, Volume: 38, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Sequence; Arthritis, Rheumatoid; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Female; Humans; Leucine; Male; Middle Aged; Molecular Sequence Data; Osteoarthritis; Pancreatic Elastase; Spinal Diseases; Substrate Specificity; Synovial Fluid

1992
Detection of peptidases in Trypanosoma cruzi epimastigotes using chromogenic and fluorogenic substrates.
    Parasitology, 1992, Volume: 104 ( Pt 2)

    Topics: Amino Acid Sequence; Aminopeptidases; Animals; Chromogenic Compounds; Coumarins; Dipeptides; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Hydrogen-Ion Concentration; Hydrolysis; Molecular Sequence Data; Peptide Hydrolases; Protease Inhibitors; Substrate Specificity; Trypanosoma cruzi

1992
Changes of lysosomal proteinase activities and their expression in rat cultured keratinocytes during differentiation.
    Biochimica et biophysica acta, 1991, Sep-24, Volume: 1094, Issue:3

    Topics: Animals; Cathepsin B; Cathepsin L; Cathepsins; Cell Differentiation; Cells, Cultured; Coumarins; Cystatins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Immunoblotting; Keratinocytes; Lysosomes; Protease Inhibitors; Rats

1991
A model to explain the pH-dependent specificity of cathepsin B-catalysed hydrolyses.
    The Biochemical journal, 1991, May-01, Volume: 275 ( Pt 3)

    Topics: Cathepsin B; Coumarins; Dipeptides; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Liver; Substrate Specificity

1991
Study of thiol proteases of normal human skin fibroblasts.
    Cell biochemistry and function, 1991, Volume: 9, Issue:1

    Topics: Caseins; Cathepsin B; Cathepsin H; Cathepsin L; Cathepsins; Cell Fractionation; Cells, Cultured; Concanavalin A; Coumarins; Cysteine Endopeptidases; Dipeptides; Endopeptidases; Fibroblasts; Humans; Hydrogen-Ion Concentration; Hymecromone; Leupeptins; Lysosomes; Microsomes; Skin

1991
A cryptic meprin-like proteolytic activity in mouse kidney brush border membranes.
    The International journal of biochemistry, 1990, Volume: 22, Issue:9

    Topics: Animals; Blotting, Western; Coumarins; Dipeptides; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Hydrolysis; Kidney; Metalloendopeptidases; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microvilli; Papain; Phenotype; Protein Precursors; Substrate Specificity; Tiopronin; Trypsin

1990
[Photometric method of determination of the amidase activity of proteinases using 4-methylcoumaryl-7-amide substrates].
    Bioorganicheskaia khimiia, 1990, Volume: 16, Issue:5

    Topics: Amino Acid Sequence; Coumarins; Dipeptides; Humans; Kallikreins; Kinetics; Molecular Sequence Data; Oligopeptides; Photometry; Spectrometry, Fluorescence; Substrate Specificity; Urokinase-Type Plasminogen Activator

1990
Species variants of cathepsin L and their immunological identification.
    The Biochemical journal, 1986, Nov-15, Volume: 240, Issue:1

    Topics: Animals; Cathepsin L; Cathepsins; Cattle; Coumarins; Cysteine Endopeptidases; Diazomethane; Dipeptides; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Epitopes; Humans; Immunoelectrophoresis; Isoenzymes; Kinetics; Leucine; Protease Inhibitors; Rabbits; Rats; Sheep; Species Specificity

1986
Cathepsin L activity in alveolar macrophages of rats: response to cigarette smoke.
    American journal of respiratory cell and molecular biology, 1989, Volume: 1, Issue:5

    Topics: Animals; Biomarkers; Body Weight; Bronchoalveolar Lavage Fluid; Cathepsin L; Cathepsins; Coumarins; Cysteine Endopeptidases; Dipeptides; Endopeptidases; Fluorescent Dyes; Macrophages; Male; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Smoking

1989
Human kidney cathepsins B and L. Characterization and potential role in degradation of glomerular basement membrane.
    The Biochemical journal, 1988, May-15, Volume: 252, Issue:1

    Topics: Basement Membrane; Cathepsin B; Cathepsin L; Cathepsins; Coumarins; Cysteine Endopeptidases; Dipeptides; Endopeptidases; Humans; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Kidney Glomerulus; Kinetics; Microbial Collagenase; Pancreatic Elastase; Trypsin

1988
Involvement of thiol proteases in galactosialidosis.
    Clinica chimica acta; international journal of clinical chemistry, 1986, Mar-16, Volume: 155, Issue:2

    Topics: beta-Galactosidase; Cathepsin B; Cathepsin H; Cathepsins; Cells, Cultured; Coumarins; Cysteine Endopeptidases; Diazomethane; Dipeptides; Endopeptidases; Fibroblasts; Galactosidases; Humans; Leucine; Leupeptins; Neuraminidase; Protease Inhibitors

1986
The identification of the major excreted protein (MEP) from a transformed mouse fibroblast cell line as a catalytically active precursor form of cathepsin L.
    The Biochemical journal, 1987, Dec-01, Volume: 248, Issue:2

    Topics: Binding Sites; Caseins; Cathepsin L; Cathepsins; Cell Line, Transformed; Coumarins; Cysteine Endopeptidases; Dipeptides; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enzyme Precursors; Hydrogen-Ion Concentration; Leucine; Serum Albumin, Bovine

1987
[A high peptidase activity specific for hydrolysis of Z-Phe-Arg-MCA from human serum during pregnancy].
    Nihon Sanka Fujinka Gakkai zasshi, 1986, Volume: 38, Issue:6

    Topics: Coumarins; Dipeptides; Female; Humans; Hydrolysis; Peptide Hydrolases; Placental Function Tests; Pregnancy

1986
Determination of factor XII by functional assay with fluorogenic substrate and enzyme immunoassay.
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1985, Volume: 48, Issue:1

    Topics: Coumarins; Dipeptides; Factor XII; Humans; Immunoenzyme Techniques

1985
The proteolytic activities of chymopapain, papain, and papaya proteinase III.
    Biochimica et biophysica acta, 1985, Apr-05, Volume: 828, Issue:2

    Topics: Albumins; Binding Sites; Cartilage; Caseins; Chymopapain; Coumarins; Dipeptides; Electrophoresis; Endopeptidases; Immunodiffusion; Kinetics; Papain; Phosphorylase a; Proteoglycans; Serum Albumin; Serum Albumin, Bovine

1985
Automated measurement of proteinase activity with a fluorogenic substrate using an inverted fluorescence microscope.
    Analytical biochemistry, 1982, Volume: 126, Issue:1

    Topics: Coumarins; Dipeptides; Endopeptidases; Indicators and Reagents; Microscopy, Fluorescence; Photometry; Schistosoma mansoni

1982
Fluorimetric assays for cathepsin B and cathepsin H with methylcoumarylamide substrates.
    The Biochemical journal, 1980, Jun-01, Volume: 187, Issue:3

    Topics: Animals; Arginine; Cathepsin B; Cathepsin H; Cathepsins; Coumarins; Cysteine Endopeptidases; Dipeptides; Humans; Lysosomes; Rats; Spectrometry, Fluorescence; Substrate Specificity

1980
Peptide aldehydes and nitriles as transition state analog inhibitors of cysteine proteases.
    Biochemistry, 1995, Jul-18, Volume: 34, Issue:28

    Topics: Aldehydes; Animals; Coumarins; Cysteine Proteinase Inhibitors; Dipeptides; Enzyme Stability; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Kinetics; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Nitriles; Papain; Peptides; Substrate Specificity; Thermodynamics

1995
Excystment of Paragonimus westermani metacercariae by endogenous cysteine protease.
    The Journal of parasitology, 1995, Volume: 81, Issue:2

    Topics: Animals; Chromatography, Ion Exchange; Collagen; Coumarins; Cysteine Endopeptidases; Dipeptides; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Fibronectins; Hydrogen-Ion Concentration; Iodoacetamide; Leucine; Leupeptins; Myosins; Oligopeptides; Pancreatic Elastase; Paragonimus; Temperature; Trypsin

1995
Trypanosomatid cysteine protease activity may be enhanced by a kininogen-like moiety from host serum.
    The Biochemical journal, 1995, Jan-15, Volume: 305 ( Pt 2)

    Topics: Animals; Coumarins; Cysteine Endopeptidases; Dipeptides; Dose-Response Relationship, Drug; Fluorescent Dyes; Hydrolysis; Kininogens; Leishmania; Trypanosoma; Trypanosomatina

1995
Plasmodium falciparum: effects of proteinase inhibitors on globin hydrolysis by cultured malaria parasites.
    Experimental parasitology, 1995, Volume: 80, Issue:2

    Topics: Animals; Antimalarials; Chymotrypsin; Coumarins; Cysteine Proteinase Inhibitors; Dipeptides; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Fluorescent Dyes; Globins; Humans; Hydrolysis; Leucine; Leupeptins; Oligopeptides; Pepstatins; Plasmodium falciparum; Vacuoles

1995
Secretion of cysteine proteinase activity by the zoonotic hookworm Ancylostoma caninum.
    The American journal of tropical medicine and hygiene, 1994, Volume: 51, Issue:3

    Topics: Amino Acid Sequence; Ancylostoma; Ancylostomiasis; Animals; Antigens, Helminth; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Dithiothreitol; Dogs; Electrophoresis, Polyacrylamide Gel; Female; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Male; Molecular Sequence Data; Substrate Specificity; Zoonoses

1994
A proteolytic activity enhanced by arsenite in Chinese hamster ovary cells: possible involvement in arsenite-induced cell killing.
    Biochemical and biophysical research communications, 1994, Jul-29, Volume: 202, Issue:2

    Topics: Animals; Arsenites; Cell Death; CHO Cells; Coumarins; Cricetinae; Dipeptides; Dithiothreitol; Endopeptidases; Fluorescent Dyes; Hydrogen-Ion Concentration; Molecular Weight; Protease Inhibitors; Sodium Compounds; Substrate Specificity

1994
Characterization of the cysteine proteinases of the common liver fluke Fasciola hepatica using novel, active-site directed affinity labels.
    Parasitology, 1993, Volume: 106 ( Pt 5)

    Topics: Affinity Labels; Animals; Biotin; Coumarins; Culture Media; Cysteine Endopeptidases; Diazomethane; Dipeptides; Fasciola hepatica; Fluorescent Dyes; Hydrogen-Ion Concentration; Hydrolysis; Molecular Weight; Oligopeptides; Spectrometry, Fluorescence; Substrate Specificity

1993
Biochemical properties of purified cathepsin B from Schistosoma mansoni.
    International journal for parasitology, 1995, Volume: 25, Issue:12

    Topics: Amino Acid Sequence; Animals; Cathepsin B; Coumarins; Dipeptides; Globins; Hydrogen-Ion Concentration; Immunochemistry; Molecular Sequence Data; Oligopeptides; Schistosoma mansoni; Substrate Specificity

1995
Delineating functionally important regions and residues in the cathepsin B propeptide for inhibitory activity.
    FEBS letters, 1996, Sep-09, Volume: 393, Issue:1

    Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Cathepsin B; Coumarins; Dipeptides; Molecular Sequence Data; Peptide Fragments; Protein Precursors; Rats

1996
Role of the occluding loop in cathepsin B activity.
    The Journal of biological chemistry, 1997, Jan-10, Volume: 272, Issue:2

    Topics: Amino Acid Sequence; Cathepsin B; Coumarins; Cystatin C; Cystatins; Cysteine Proteinase Inhibitors; Dipeptides; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Protein Conformation

1997
Production of anti-peptide antibodies against trypanopain-Tb from Trypanosoma brucei brucei: effects of antibodies on enzyme activity against Z-Phe-Arg-AMC.
    Immunopharmacology, 1997, Volume: 36, Issue:2-3

    Topics: Animals; Antibodies, Protozoan; Antibody Formation; Binding Sites; Chickens; Coumarins; Cysteine Endopeptidases; Dipeptides; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Rabbits; Structure-Activity Relationship; Trypanosoma brucei brucei

1997
Tumor-associated cysteine proteinase activities in human melanoma cells and fibroblasts of different origin.
    European journal of cell biology, 1997, Volume: 73, Issue:4

    Topics: Cell Line; Coumarins; Cysteine Endopeptidases; Diazomethane; Dipeptides; Fibroblasts; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Melanoma; Middle Aged; Neoplasm Invasiveness; Neoplasm Proteins; Skin; Skin Neoplasms; Tumor Cells, Cultured; Urea

1997
Expression in Escherichia coli, refolding, and purification of human procathepsin K, an osteoclast-specific protease.
    Protein expression and purification, 1999, Volume: 15, Issue:2

    Topics: Amino Acid Sequence; Cathepsin K; Cathepsins; Coumarins; Dipeptides; Enzyme Activation; Escherichia coli; Fluorescent Dyes; Humans; Inclusion Bodies; Molecular Sequence Data; Osteoclasts; Protein Precursors; Recombinant Fusion Proteins

1999
Modulation of the catalytic activity of cruzipain, the major cysteine proteinase from Trypanosoma cruzi, by temperature and pH.
    European journal of biochemistry, 2001, Volume: 268, Issue:11

    Topics: Animals; Caseins; Catalysis; Coumarins; Cysteine Endopeptidases; Dipeptides; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Protozoan Proteins; Substrate Specificity; Temperature; Thermodynamics; Trypanosoma cruzi

2001
Reversible inhibition of cathepsin L-like proteases by 4-mer pseudopeptides.
    FEBS letters, 2001, Nov-02, Volume: 507, Issue:3

    Topics: Cathepsin B; Cathepsin L; Cathepsins; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Oligopeptides; Peptides; Protozoan Proteins; Structure-Activity Relationship

2001
The N-terminal part of recombinant human tear lipocalin/von Ebner's gland protein confers cysteine proteinase inhibition depending on the presence of the entire cystatin-like sequence motifs.
    Biological chemistry, 2001, Volume: 382, Issue:10

    Topics: Amino Acid Motifs; Amino Acid Sequence; Carrier Proteins; Coumarins; Cystatins; Dipeptides; Enteropeptidase; Humans; Lipocalin 1; Molecular Sequence Data; Mutation; Papain; Recombinant Proteins

2001
Kinetics of parasite cysteine proteinase inactivation by NO-donors.
    Biochemical and biophysical research communications, 2004, Mar-12, Volume: 315, Issue:3

    Topics: Animals; Ascorbic Acid; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Dithiothreitol; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Leishmania infantum; Nitric Oxide Donors; Papain; Parasites; Plasmodium falciparum; Protozoan Proteins; Trypanosoma cruzi

2004
Interplay between acid phosphatase and cysteine proteases in mediating vitellin degradation during early embryogenesis of Periplaneta americana.
    Journal of insect physiology, 2008, Volume: 54, Issue:5

    Topics: Acid Phosphatase; Age Factors; Animals; Coumarins; Cysteine Endopeptidases; Dipeptides; Egg Proteins; Enzyme-Linked Immunosorbent Assay; Hydrogen-Ion Concentration; Periplaneta; Phosphoamino Acids; Vitellins

2008
A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus.
    Molecular and biochemical parasitology, 2008, Volume: 160, Issue:2

    Topics: Amino Acid Sequence; Animals; Cathepsin B; Cloning, Molecular; Coumarins; Cricetinae; Dipeptides; Escherichia coli; Gelatin; Gene Expression; Gene Expression Profiling; Haemonchus; Hemoglobins; Mice; Molecular Sequence Data; Necator americanus; Phylogeny; Pichia; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Up-Regulation

2008
Identification and characterization of a cathepsin L-like cysteine protease from Gnathostoma spinigerum.
    Molecular and biochemical parasitology, 2008, Volume: 160, Issue:2

    Topics: Amino Acid Sequence; Animals; Base Sequence; Caenorhabditis elegans; Cathepsin L; Cathepsins; Cloning, Molecular; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Gene Expression; Gene Library; Gnathostoma; Humans; Molecular Sequence Data; Molecular Weight; Open Reading Frames; Phylogeny; Pichia; Protein Sorting Signals; Protein Structure, Tertiary; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Substrate Specificity

2008
Differences in cysteine protease activity in Schistosoma mansoni-resistant and -susceptible Biomphalaria glabrata and characterization of the hepatopancreas cathepsin B Full-length cDNA.
    The Journal of parasitology, 2008, Volume: 94, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Biomphalaria; Cathepsin B; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Expressed Sequence Tags; Fluorescent Dyes; Fluorometry; Gene Library; Hepatopancreas; Host-Parasite Interactions; Immunity, Innate; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction; Schistosoma mansoni

2008
Cysteine peptidases from Phytomonas serpens: biochemical and immunological approaches.
    FEMS immunology and medical microbiology, 2009, Volume: 57, Issue:3

    Topics: Animals; Antibodies, Protozoan; Cell Membrane; Coumarins; Cysteine Proteases; Cytoplasm; Dipeptides; Flagella; Humans; Immunohistochemistry; Molecular Weight; Proteins; Protozoan Proteins; Trypanosomatina

2009
Identification of essential residues of CTLA-2alpha for inhibitory potency.
    Journal of biochemistry, 2010, Volume: 147, Issue:3

    Topics: Amino Acid Sequence; Animals; Antigens, Differentiation; Cathepsin L; Coumarins; Dipeptides; Enzyme Inhibitors; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Stability; Protein Structure, Tertiary; Rabbits; Recombinant Proteins; Sequence Deletion; Structure-Activity Relationship

2010
A cysteine endopeptidase ("dionain") is involved in the digestive fluid of Dionaea muscipula (Venus's fly-trap).
    Bioscience, biotechnology, and biochemistry, 2011, Volume: 75, Issue:2

    Topics: Amino Acid Sequence; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Digestion; Dipeptides; Droseraceae; Hydrogen-Ion Concentration; Molecular Sequence Data

2011
Insecticidal effect of Canavalia ensiformis major urease on nymphs of the milkweed bug Oncopeltus fasciatus and characterization of digestive peptidases.
    Insect biochemistry and molecular biology, 2011, Volume: 41, Issue:6

    Topics: Amino Acid Sequence; Animals; Base Sequence; Canavalia; Cathepsin L; Chromatography, Ion Exchange; Coumarins; Cysteine Proteinase Inhibitors; Digestion; Dipeptides; Electrophoresis, Polyacrylamide Gel; Heteroptera; Hydrogen-Ion Concentration; Hydrolysis; Insecticides; Leucine; Molecular Sequence Data; Nymph; Peptide Fragments; Plant Proteins; Protein Precursors; Urease

2011
Chlorhexidine inhibits the activity of dental cysteine cathepsins.
    Journal of dental research, 2012, Volume: 91, Issue:4

    Topics: Adult; Cathepsin B; Cathepsin K; Cathepsin L; Cathepsins; Chlorhexidine; Coumarins; Cysteine Proteinase Inhibitors; Dentin; Dipeptides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Dyes; Humans; Hydrolysis; Leucine; Matrix Metalloproteinase Inhibitors; Models, Molecular; Protein Binding; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence; Young Adult

2012
Clusterin is a specific stabilizer and liberator of extracellular cathepsin K.
    FEBS letters, 2012, Apr-05, Volume: 586, Issue:7

    Topics: Cathepsin K; Chromatography, Affinity; Clusterin; Coumarins; Cysteine Proteinase Inhibitors; Dipeptides; Enzyme Stability; Enzymes, Immobilized; Extracellular Space; Humans; Hydrogen-Ion Concentration; Kinetics; Ligands; Models, Biological; Osmolar Concentration; Proteolysis; Recombinant Proteins

2012
Enzymatic characterization of germination-specific cysteine protease-1 expressed transiently in cotyledons during the early phase of germination.
    Journal of biochemistry, 2013, Volume: 153, Issue:1

    Topics: Amino Acid Sequence; Catalytic Domain; Cotyledon; Coumarins; Cysteine; Cysteine Endopeptidases; Cystine; Dipeptides; Gene Expression Regulation, Plant; Germination; Indicators and Reagents; Japan; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Plant Proteins; Proteolysis; Raphanus; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity

2013
Binding of chondroitin 4-sulfate to cathepsin S regulates its enzymatic activity.
    Biochemistry, 2013, Sep-17, Volume: 52, Issue:37

    Topics: Binding Sites; Cathepsins; Chondroitin Sulfates; Chromatography, Gel; Collagen Type IV; Coumarins; Dipeptides; Humans; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Surface Plasmon Resonance

2013