benzyl-alpha-n-acetylgalactosamine and fluorouracil

benzyl-alpha-n-acetylgalactosamine has been researched along with fluorouracil in 2 studies

*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]

Compound Research Comparison

Studies (benzyl-alpha-n-acetylgalactosamine)	Trials (benzyl-alpha-n-acetylgalactosamine)	Recent Studies (post-2010) (benzyl-alpha-n-acetylgalactosamine)	Studies (fluorouracil)	Trials (fluorouracil)	Recent Studies (post-2010) (fluorouracil)
55	0	9	45,562	9,307	14,663

Protein Interaction Comparison

Protein	Taxonomy	fluorouracil (IC50)
Epidermal growth factor receptor	Homo sapiens (human)	0.32
Thymidylate synthase	Mus musculus (house mouse)	1.58
Aromatase	Homo sapiens (human)	0.63

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Campbell, RB; Kalra, AV	2

Other Studies

2 other study(ies) available for benzyl-alpha-n-acetylgalactosamine and fluorouracil

Article	Year
Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: overcoming cellular barriers for therapeutic gain. British journal of cancer, 2007, Oct-08, Volume: 97, Issue:7 Topics: Acetylgalactosamine; Antimetabolites, Antineoplastic; Benzyl Compounds; Cell Proliferation; Fluorescent Antibody Technique; Fluorouracil; Glioblastoma; Glycosylation; Humans; Microscopy, Fluorescence; Mucin-1; N-Acetylneuraminic Acid; Neuraminidase; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured	2007
Mucin overexpression limits the effectiveness of 5-FU by reducing intracellular drug uptake and antineoplastic drug effects in pancreatic tumours. European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:1 Topics: Acetylgalactosamine; Animals; Antineoplastic Agents; Benzyl Compounds; Cell Line, Tumor; Female; Fluorouracil; Glycosylation; Mice; Mucin-1; Pancreatic Neoplasms; Treatment Failure; Xenograft Model Antitumor Assays	2009

Article

Year

Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: overcoming cellular barriers for therapeutic gain.

British journal of cancer, 2007, Oct-08, Volume: 97, Issue:7

Topics: Acetylgalactosamine; Antimetabolites, Antineoplastic; Benzyl Compounds; Cell Proliferation; Fluorescent Antibody Technique; Fluorouracil; Glioblastoma; Glycosylation; Humans; Microscopy, Fluorescence; Mucin-1; N-Acetylneuraminic Acid; Neuraminidase; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured

2007

Mucin overexpression limits the effectiveness of 5-FU by reducing intracellular drug uptake and antineoplastic drug effects in pancreatic tumours.

European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:1

Topics: Acetylgalactosamine; Animals; Antineoplastic Agents; Benzyl Compounds; Cell Line, Tumor; Female; Fluorouracil; Glycosylation; Mice; Mucin-1; Pancreatic Neoplasms; Treatment Failure; Xenograft Model Antitumor Assays

2009