Page last updated: 2024-08-21

benzydamine and benzydamine n-oxide

benzydamine has been researched along with benzydamine n-oxide in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Baldock, GA; Brodie, RR; Chasseaud, LF; Taylor, T1
Catanese, B; Lagana, A; Marino, A; Picollo, R; Rotatori, M1
Chikaoka, Y; Isobe, M; Kawaji, A; Nomura, Y; Takabatake, E; Tamura, M; Tochino, Y1
Lang, DH; Rettie, AE1
Anfossi, P; Capolongo, F; Coldham, NG; Montesissa, C; Santi, A; Sauer, MJ1
Kume, T; Shimizu, M; Taniguchi-Takizawa, T; Yamazaki, H1
Mitsui, M; Nishiwaki, M; Shimizu, M; Suemizu, H; Yamazaki, H; Yamazaki-Nishioka, M1
Bovi, G; Caccia, G; Comandini, A; Di Stefano, AFD; Focanti, F; Olivieri, S; Pelacchi, F; Picollo, R; Radicioni, MM; Rosignoli, MT; Salvatori, E; Vaccani, A1

Trials

1 trial(s) available for benzydamine and benzydamine n-oxide

ArticleYear
Phase I Study in Healthy Women of a Novel Antimycotic Vaginal Ovule Combining Econazole and Benzydamine.
    Infectious diseases in obstetrics and gynecology, 2020, Volume: 2020

    Topics: Administration, Oral; Adult; Antifungal Agents; Area Under Curve; Benzydamine; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Delivery Systems; Econazole; Female; Healthy Volunteers; Humans; Middle Aged; Vagina; Young Adult

2020

Other Studies

7 other study(ies) available for benzydamine and benzydamine n-oxide

ArticleYear
Determination of benzydamine and its N-oxide in biological fluids by high-performance liquid chromatography.
    Journal of chromatography, 1990, Jul-13, Volume: 529, Issue:1

    Topics: Benzydamine; Chromatography, High Pressure Liquid; Humans

1990
HPLC determination of benzydamine and its metabolite N-oxide in plasma following oral administration or topical application in man, using fluorimetric detection.
    Pharmacological research communications, 1986, Volume: 18, Issue:4

    Topics: Administration, Oral; Administration, Topical; Adult; Aged; Anti-Inflammatory Agents; Benzydamine; Chromatography, High Pressure Liquid; Female; Humans; Kinetics; Male; Middle Aged; Pyrazoles; Spectrometry, Fluorescence

1986
Flavin-containing monooxygenase mediated metabolism of benzydamine in perfused brain and liver.
    Biochimica et biophysica acta, 1998, Sep-16, Volume: 1425, Issue:1

    Topics: Animals; Benzydamine; Brain; In Vitro Techniques; Kinetics; Liver; Male; Microsomes; Microsomes, Liver; Oxidation-Reduction; Oxygenases; Perfusion; Rats; Rats, Wistar; Tissue Distribution

1998
Can caffeine metabolism be used as an in-vivo probe for human flavin-containing monooxygenase activity?
    Pharmacogenetics, 2000, Volume: 10, Issue:3

    Topics: Benzydamine; Caffeine; Flavoproteins; Humans; Molecular Probes; Oxygenases; Theobromine

2000
Biotransformation of benzydamine by microsomes and precision-cut slices prepared from cattle liver.
    Xenobiotica; the fate of foreign compounds in biological systems, 2002, Volume: 32, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzydamine; Biotransformation; Cattle; Chromatography, High Pressure Liquid; Glucuronides; Humans; In Vitro Techniques; Liver; Male; Mass Spectrometry; Microsomes, Liver; Molecular Structure

2002
Benzydamine N-oxygenation as an index for flavin-containing monooxygenase activity and benzydamine N-demethylation by cytochrome P450 enzymes in liver microsomes from rats, dogs, monkeys, and humans.
    Drug metabolism and pharmacokinetics, 2015, Volume: 30, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Benzydamine; Biotransformation; Cytochrome P-450 Enzyme System; Dogs; Humans; In Vitro Techniques; Macaca fascicularis; Male; Methylation; Microsomes, Liver; Oxidation-Reduction; Oxygenases; Rats, Sprague-Dawley; Recombinant Proteins; Species Specificity

2015
Human plasma metabolic profiles of benzydamine, a flavin-containing monooxygenase probe substrate, simulated with pharmacokinetic data from control and humanized-liver mice.
    Xenobiotica; the fate of foreign compounds in biological systems, 2018, Volume: 48, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzydamine; Humans; Metabolome; Mice; Oxygenases

2018