benzphetamine has been researched along with nadp in 52 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (82.69) | 18.7374 |
| 1990's | 7 (13.46) | 18.2507 |
| 2000's | 2 (3.85) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hunter, AL; Neal, RA | 1 |
| Mayer, RT; Prough, RA | 1 |
| Coon, MJ; Nordblom, GD | 1 |
| Kicha, LP; Strickhart, FS; Yang, CS | 2 |
| Behlke, J; Blanck, J; Jänig, GR; Pfeil, D; Ruckpaul, K | 1 |
| Coon, MJ; Oprian, DD; Vatsis, KP | 1 |
| Dalvi, RR; HUNTER, AL; Neal, RA | 1 |
| Gillette, JR; Mitchell, JR; Sasame, HA; Thorgeirsson, SS | 1 |
| Conney, AH; Kuntzman, R; Levin, W; Lu, AY; Ryan, D; Vore, M; West, SB | 1 |
| Archakov, AI; Bachmanova, GI; Blinov, VM; Darovsky, BV; Davydov, DR; Dedinsky, IR; Kanaeva, IP | 1 |
| Chen, NQ; Holtzman, JL; Srivastava, SP | 1 |
| Brady, JF; Cho, AK; Di Stefano, EW | 1 |
| Montgomery, MR; Raska-Emery, P; Zychlinski, L | 1 |
| Archakov, AI; Bachmanova, GI; Davydov, DR; Dzuzenova, ChS; Kanaeva, IP; Kondrashin, SK; Petrochenko, EV; Skotselyas, ED; Turkina, IF | 1 |
| Bend, JR; Mathews, JM | 1 |
| Amelizad, Z; Bonnamour, D; Daubeze, M; Narbonne, JF; Oesch, F | 1 |
| Capdevila, J; Estabrook, RW; Falck, JR; Kim, YR; Manna, S; Martin-Wixtrom, C | 1 |
| Blanck, J; Jänig, GR; Pommerening, K; Rein, H; Ristau, O; Ruckpaul, K; Schwarze, W | 1 |
| Archakov, AI; Zhukov, AA | 1 |
| Correia, MA; Mannering, GJ | 1 |
| Estabrook, RW; Werringloer, J | 1 |
| Jacobson, M; Kuntzman, R; Levin, W; Lu, AY; McCay, PB; Poyer, JL | 1 |
| Neal, RA; Norman, BJ; Poore, RE | 1 |
| Estabrook, RW; Hrycay, EG | 1 |
| Strickhart, FS; Yang, CS | 1 |
| Coon, MJ; Hoeven, TA; Kaschnitz, RM; Strobel, HW | 1 |
| Coon, MJ; Lu, AY; Strobel, HW | 1 |
| Becker, BA; Eling, TE; Fouts, JR; Harbison, RD | 1 |
| Fouts, JR; Peters, MA | 2 |
| Fouts, JR; Hewick, DS | 1 |
| Coon, MJ; Heidema, J; Lu, AY; Strobel, HW | 1 |
| Belfi, KJ; Masters, BS; Nelson, EB; Raj, PP | 1 |
| Fouts, JR; Pohl, RJ | 1 |
| Davis, DC; Gram, TE; Guarino, AM; Reagan, RL; Schroeder, DH | 1 |
| Fouts, JR; Hansen, AR | 1 |
| Diaugustine, RP; Eling, TE; Fouts, JR | 1 |
| Coon, MJ; Strobel, HW | 1 |
| Peters, MA; Strother, A | 1 |
| Gillette, JR; Hamrick, M; Stripp, B; Zampaglione, N | 1 |
| Bend, JR; Easterling, RE; Fouts, JR; Gram, TE; Hook, GE | 1 |
| Devereux, TR; Fouts, JR | 1 |
| Mercurio, SD; Nemeth, AM | 1 |
| Hines, RN; Prough, RA | 1 |
| Alworth, WL; Ballou, DP; Hollenberg, PF; Hopkins, NE; Roberts, ES | 1 |
| Cadieu, M; Gruenke, LD; Konopka, K; Waskell, L | 1 |
| Baker, MT; Ronnenberg, WC; Wang, Y | 1 |
| Jansson, I; Schenkman, JB; Voznesensky, AI | 1 |
| Ahmed, SS; Napoli, KL; Strobel, HW | 1 |
| Ballou, DP; Hollenberg, PF; Kent, UM; Pascual, L; Roof, RA | 1 |
| Im, SC; Waskell, L; Zhang, H | 1 |
52 other study(ies) available for benzphetamine and nadp
| Article | Year |
|---|---|
Inhibition of hepatic mixed-function oxidase activity in vitro and in vivo by various thiono-sulfur-containing compounds.
Topics: Animals; Benzphetamine; Cytochrome P-450 Enzyme Inhibitors; In Vitro Techniques; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Rats; Thiones; Time Factors | 1975 |
Characterization of a metabolite-cytochrome P-450 complex derived from the aerobic metabolism of an insect juvenile hormone analog by rat microsomal fractions.
Topics: Aerobiosis; Animals; Benzphetamine; Cytochrome P-450 Enzyme System; Dioxolanes; Dioxoles; Ethyl Ethers; Hydrogen-Ion Concentration; In Vitro Techniques; Juvenile Hormones; Kinetics; Male; Microsomes, Liver; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Oxazines; Oxidants, Photochemical; Rats | 1976 |
Hydrogen peroxide formation and stoichiometry of hydroxylation reactions catalyzed by highly purified liver microsomal cytochrome P-450.
Topics: Aniline Compounds; Animals; Benzphetamine; Cyclohexanes; Cytochrome P-450 Enzyme System; Hydrogen Peroxide; Hydroxylation; Microsomes, Liver; NADP; Oxygen Consumption; Rabbits | 1977 |
Interaction between NADPH-cytochrome P-450 reductase and hepatic microsomes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzphetamine; Catalysis; Coumarins; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Ethyl Ethers; Membrane Proteins; Methylcholanthrene; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Oxygenases; Phenobarbital; Rats | 1978 |
Kinetics of elementary steps in the cytochrome P-450 reaction sequence. III. NADPH reduction of cytochrome P-450LM at different integrational levels.
Topics: Animals; Benzphetamine; Cytochrome P-450 Enzyme System; Kinetics; Microsomes, Liver; NADP; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Polyethylene Glycols; Rabbits; Solubility | 1979 |
Kinetics of reduction of purified liver microsomal cytochrome P-450 in the reconstituted enzyme system studied by stopped flow spectrophotometry.
Topics: Animals; Benzoflavones; Benzphetamine; Cytochrome P-450 Enzyme System; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Phospholipids; Rabbits; Spectrophotometry; Time Factors | 1979 |
Toxicological implications of the mixed-function oxidase catalyzed metabolism of carbon disulfide.
Topics: Animals; Benzphetamine; Carbon Disulfide; Cytochrome P-450 Enzyme System; Heme; Kinetics; Male; Malondialdehyde; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Proadifen; Protein Binding; Rats; Sulfur Oxides; Sulfur Radioisotopes | 1975 |
The role of cytochrome b5 in cytochrome P-450 enzymes.
Topics: Aminopyrine; Animals; Benzphetamine; Codeine; Cytochrome P-450 Enzyme System; Cytochromes; Electron Transport; Ethylmorphine-N-Demethylase; Hexobarbital; Hydroxylation; Kidney; Lauric Acids; Microsomes; Microsomes, Liver; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Pharmaceutical Preparations; Rats; Sheep | 1975 |
Role of cytochrome b5 in NADPH-and NADH-dependent hydroxylation by the reconstituted cytochrome P-450- or P-448-containing system.
Topics: Animals; Benzopyrene Hydroxylase; Benzphetamine; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Electron Transport; Hydroxylation; Lipid Metabolism; Methylcholanthrene; Microsomes, Liver; NAD; NADH, NADPH Oxidoreductases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Rats; Spectrum Analysis; Testosterone | 1975 |
Cytochrome C (Fe2+) as a competitive inhibitor of NADPH-dependent reduction of cytochrome P450 LM2: locating protein-protein interaction sites in microsomal electron carriers.
Topics: Amino Acid Sequence; Animals; Benzphetamine; Binding Sites; Binding, Competitive; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Humans; Kinetics; Mathematics; Microsomes, Liver; Molecular Sequence Data; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rabbits; Sequence Homology, Nucleic Acid | 1992 |
The effect of substrates and inhibitors of cytochrome P-450 on the NADPH inhibition of the ATP-dependent, hepatic, microsomal calcium pump.
Topics: Aminopyrine; Animals; Benzphetamine; Calcium; Calcium-Transporting ATPases; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Imidazoles; Male; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Proadifen; Rats; Rats, Inbred Strains | 1990 |
Spectral and inhibitory interactions of (+/-)-3,4-methylenedioxyamphetamine (MDA) and (+/-)-3,4-methylenedioxymethamphetamine (MDMA) with rat hepatic microsomes.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Benzphetamine; Cytochrome P-450 Enzyme System; Kinetics; Male; Methamphetamine; Methimazole; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; NADP; Oxidoreductases, N-Demethylating; Rats; Spectrophotometry | 1986 |
Selective inhibition of bipyridyl-stimulated NADPH oxidation by ascorbic acid.
Topics: Animals; Ascorbic Acid; Benzphetamine; Diquat; Drug Interactions; Ethylmorphine; Lung; Male; Microsomes; NADP; Oxidation-Reduction; Paraquat; Pyridinium Compounds; Rats; Rats, Inbred F344 | 1987 |
Reduction and catalytic properties of cytochrome P-450 LM2 in reconstituted system containing monomeric carriers.
Topics: Animals; Benzphetamine; Catalysis; Cytochrome P-450 Enzyme System; Kinetics; Macromolecular Substances; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Rabbits; Temperature | 1987 |
N-alkylaminobenzotriazoles as isozyme-selective suicide inhibitors of rabbit pulmonary microsomal cytochrome P-450.
Topics: Alkylation; Animals; Benzphetamine; Cytochrome P-450 Enzyme Inhibitors; Isoenzymes; Lung; Male; Microsomes; NADP; Oxazines; Oxygenases; Rabbits; Rats; Rats, Inbred Strains; Triazoles | 1986 |
Monooxygenase activity of systems reconstituted with fractions from rats fed standard and low protein diets.
Topics: Animals; Benzphetamine; Cytochrome P-450 Enzyme System; Dietary Proteins; Ethylmorphine; Microsomes, Liver; NADP; Oxygenases; Rats; Rats, Inbred Strains | 1986 |
Influence of a fibric acid type of hypolipidemic agent on the oxidative metabolism of arachidonic acid by liver microsomal cytochrome P-450.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Benzphetamine; Chromatography, High Pressure Liquid; Clofibrate; Clofibric Acid; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Fibric Acids; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Hypolipidemic Agents; Lauric Acids; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1985 |
Spin state control of cytochrome P-450 reduction and catalytic activity in a reconstituted P-450 LM2 system as induced by a series of benzphetamine analogues.
Topics: Animals; Benzphetamine; Cytochrome P-450 Enzyme System; Male; Mathematics; Microsomes, Liver; Models, Chemical; NADH Dehydrogenase; NADP; Phenethylamines; Rabbits; Rats | 1985 |
[Stoichiometry of microsomal oxidation reactions. Distribution of redox-equivalents in monooxygenase and oxidase reactions catalyzed by cytochrome P-450].
Topics: Aniline Hydroxylase; Animals; Benzphetamine; Catalysis; Cytochrome P-450 Enzyme System; Electron Transport; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Models, Biological; NADP; Oxidation-Reduction; Oxidoreductases; Rabbits; Substrate Specificity | 1985 |
Reduced diphosphopyridine nucleotide synergism of the reduced triphosphopyridine nucleotide-dependent mixed-function oxidase system of hepatic microsomes. II. Role of the type I drug-binding site of cytochrome P-450.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Codeine; Cyanides; Cytochrome P-450 Enzyme System; Drug Synergism; Female; Hydroxylation; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Morphinans; NAD; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Phospholipases; Proadifen; Protein Binding; Rats | 1973 |
Evidence for an inhibitory product-cytochrome P-450 complex generated during benzphetamine metabolism by liver microsomes.
Topics: Aerobiosis; Animals; Appetite Depressants; Benzphetamine; Binding Sites; Cytochrome P-450 Enzyme System; Ethanol; Hexobarbital; Kinetics; Male; Microsomes, Liver; Morphine; NADP; Oxidoreductases, N-Demethylating; Phenethylamines; Protein Binding; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors | 1973 |
Lipid peroxidation and the degradation of cytochrome P-450 heme.
Topics: Aminopyrine; Animals; Benzopyrenes; Benzphetamine; Carbon Monoxide; Chromatography, Paper; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Levulinic Acids; Lipid Metabolism; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidation-Reduction; Pentobarbital; Peroxidases; Phenobarbital; Protein Binding; Rats; Secobarbital; Spectrophotometry; Time Factors; Tritium | 1973 |
Studies of the binding of sulfur released in the mixed-function oxidase-catalyzed metabolism of diethyl p-nitrophenyl phosphorothionate(parathion) to diethyl p-nitrophenyl phosphate (paraoxon).
Topics: Animals; Benzphetamine; Carbon Monoxide; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Dealkylation; Esterases; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidoreductases; Paraoxon; Parathion; Phenobarbital; Solvents; Sulfur; Sulfur Radioisotopes | 1974 |
The effect of extra bound cytochrome b-5 on cytochrome P-450-dependent enzyme activities in liver microsomes.
Topics: Anaerobiosis; Animals; Benzphetamine; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Kinetics; Male; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Peroxidases; Phenobarbital; Rabbits; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors; Ultracentrifugation | 1974 |
Inhibition of hepatic mixed function oxidase activity by propyl gallate.
Topics: Aging; Aminopyrine N-Demethylase; Animals; Benzopyrenes; Benzphetamine; Cytochrome c Group; Cytochrome P-450 Enzyme Inhibitors; Cytochrome Reductases; Diet; Gallic Acid; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Methyltransferases; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NADP; Oxidoreductases; Phenobarbital; Rats; Spectrophotometry, Ultraviolet | 1974 |
Biochemical studies on cytochrome P-450 solubilized from liver microsomes: partial purification and mechanism of catalysis.
Topics: Animals; Benzphetamine; Catalysis; Cytochrome P-450 Enzyme System; Electron Transport; In Vitro Techniques; Microsomes, Liver; NADP; Oxidation-Reduction; Phosphatidylcholines; Rabbits; Solubility; Superoxide Dismutase | 1973 |
Hydroxylation of benzphetamine and other drugs by a solubilized form of cytochrome P-450 from liver microsomes: lipid requirement for drug demethylation.
Topics: Aminopyrine; Animals; Appetite Depressants; Benzphetamine; Cytochromes; Depression, Chemical; Ethers; Fatty Acids; Formaldehyde; Hexobarbital; Lipid Metabolism; Liver; Microsomes; Mixed Function Oxygenases; Morphinans; NADP; Oxidoreductases; Phenethylamines; Phenobarbital; Propylamines; Rabbits; Spectrophotometry | 1969 |
Kinetic changes in microsomal drug metabolism with age and diphenylhydantoin treatment.
Topics: Age Factors; Aniline Compounds; Animals; Benzphetamine; Cytochromes; Enzyme Induction; Female; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenytoin; Rats | 1970 |
A study of some possible mechanisms by which magnesium activates hepatic microsomal drug metabolism in vitro.
Topics: Aniline Compounds; Animals; Benzphetamine; Chlortetracycline; Cytochromes; Electron Transport; In Vitro Techniques; Magnesium; Male; Microsomes, Liver; NADP; Oxidoreductases; Phenobarbital; Rats | 1970 |
The metabolism in vitro and hepatic microsomal interactions of some enantiomeric drug substrates.
Topics: Amphetamine; Animals; Appetite Depressants; Benzphetamine; Dextroamphetamine; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; NADP; Oxidoreductases; Phenethylamines; Propylamines; Rabbits; Spectrum Analysis; Stereoisomerism | 1970 |
Phosphatidylcholine requirement in the enzymatic reduction of hemoprotein P-450 and in fatty acid, hydrocarbon, and drug hydroxylation.
Topics: Alkanes; Animals; Benzphetamine; Carbon Monoxide; Electron Transport; Fatty Acids; Heme; Kinetics; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Phosphatidylcholines; Rats; Spectrophotometry | 1970 |
The influence of magnesium and some other divalent cations on hepatic microsomal drug metabolism in vitro.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Calcium; Chlorides; Cobalt; Copper; Cytochromes; Edetic Acid; Hexobarbital; In Vitro Techniques; Iron; Magnesium; Male; Manganese; Microsomes, Liver; NADP; Nitrophenols; Phenobarbital; Potassium; Rats; Strontium; Sulfates; Zinc; Zoxazolamine | 1970 |
Oxidative drug metabolism in human liver microsomes.
Topics: Adolescent; Adult; Aminopyrine; Aniline Compounds; Benzphetamine; Biotransformation; Chlorpromazine; Codeine; Cytochromes; Dealkylation; Dextropropoxyphene; Female; Humans; Immunodiffusion; In Vitro Techniques; Male; Microsomes, Liver; Middle Aged; Morphinans; NADP; Oxidoreductases; Spectrophotometry | 1971 |
Further studies on the effects of metal ions on rat liver microsomal reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase.
Topics: Aniline Compounds; Animals; Benzphetamine; Calcium Chloride; Cytochromes; Female; Hydrogen-Ion Concentration; Magnesium; Male; Manganese; Metals; Microsomes, Liver; NADP; Osmolar Concentration; Oxidoreductases; Potassium Chloride; Rats; Spectrophotometry; Stimulation, Chemical | 1971 |
Enzymic and biochemical composition of smooth and rough microsomal membranes from monkey, guinea pig and mouse liver.
Topics: Aniline Compounds; Animals; Benzphetamine; Centrifugation, Density Gradient; Cesium; Cholesterol; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Dealkylation; Electron Transport; Glucuronates; Guinea Pigs; Haplorhini; Hexosyltransferases; Humans; In Vitro Techniques; Macaca; Male; Membranes; Methyltransferases; Mice; Microscopy, Electron; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NADP; Nucleoside Diphosphate Sugars; Oxidoreductases; Phospholipids; Proteins; RNA; Species Specificity; Spectrophotometry; Uracil Nucleotides | 1971 |
A comparison of the effects of benzypyrene administration on some hepatic microsomal mixed-function oxidases of rats and mice.
Topics: Aniline Compounds; Animals; Benzopyrenes; Benzphetamine; Cytochromes; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Light; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; NADP; Oxidoreductases; Rats; Rats, Inbred Strains; Spectrum Analysis | 1971 |
The interaction of a fluorescent probe with rat hepatic microsomes.
Topics: Aniline Compounds; Animals; Benzphetamine; Binding Sites; Fluorometry; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Naphthalenes; Oxidoreductases; Phenobarbital; Rats; Sulfites; Sulfonic Acids; Warfarin | 1970 |
Effect of superoxide generation and dismutation on hydroxylation reactions catalyzed by liver microsomal cytochrome P-450.
Topics: Animals; Benzphetamine; Cattle; Cytochromes; Formaldehyde; Free Radicals; Hydroxylation; Microsomes, Liver; Models, Chemical; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen; Phosphatidylcholines; Rats; Sodium Chloride; Xanthine Oxidase | 1971 |
A study of some possible mechanisms by which glucose inhibits drug metabolism in vivo and in vitro.
Topics: Animals; Barbiturates; Benzphetamine; Brain Chemistry; Carbon Isotopes; Electron Transport Complex IV; Glucose; Glucosephosphate Dehydrogenase; Hexobarbital; Kinetics; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; NADP; Organ Size; Oxidoreductases; Pentobarbital; Sleep | 1972 |
An approach measurement of the stoichiometric relationship between hepatic microsomal drug metabolism and the oxidation of reduced nicotinamide adenine dinucleotide phosphate.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Benzyl Compounds; Chlorine; Dealkylation; Ethylamines; Hexobarbital; Imipramine; Male; Methylamines; Microsomes, Liver; Morphine; NADP; Oxidation-Reduction; Pharmaceutical Preparations; Rats | 1972 |
A comparative study of the hepatic and pulmonary microsomal mixed-function oxidase systems in the rabbit.
Topics: Aniline Compounds; Animals; Benzphetamine; Biphenyl Compounds; Buffers; Cytochrome c Group; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Kinetics; Liver; Lung; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Oxidoreductases, N-Demethylating; Proadifen; Proteins; Rabbits; Spectrophotometry | 1972 |
Developmental aspects of hepatic and extrahepatic drug-metabolizing enzyme systems: microsomal enzymes and components in rabbit liver and lung during the first month of life.
Topics: Aging; Animals; Animals, Newborn; Benzopyrenes; Benzphetamine; Body Weight; Cytochrome P-450 Enzyme System; Cytochromes; Electron Transport; Female; Lung; Male; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; NADP; Organ Size; Oxidoreductases; Rabbits | 1972 |
Regulation of monooxygenation during development of chick embryo liver: role of cytochrome P-450 isozymes and NADPH.
Topics: Animals; Benzphetamine; Chick Embryo; Codeine; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Ethylmorphine; Hydrogen Peroxide; Isoenzymes; Liver; NADP; Phenobarbital; Testosterone | 1983 |
The characterization of an inhibitory complex formed with cytochrome P-450 and a metabolite of 1,1-disubstituted hydrazines.
Topics: Animals; Benzphetamine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Hydrazines; Kinetics; Microsomes, Liver; NADP; Nitric Oxide; Nitrosamines; Oxidation-Reduction; Pharmaceutical Preparations; Piperidines; Rats; Safrole; Spectrophotometry | 1980 |
Mechanistic studies of 9-ethynylphenanthrene-inactivated cytochrome P450 2B1.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzphetamine; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hydrogen Peroxide; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Phenanthrenes; Rats; Spectrum Analysis; Steroid Hydroxylases | 1995 |
The stoichiometry of the cytochrome P-450-catalyzed metabolism of methoxyflurane and benzphetamine in the presence and absence of cytochrome b5.
Topics: Animals; Benzphetamine; Cytochrome P-450 Enzyme System; Cytochromes b5; Dealkylation; Male; Methoxyflurane; NADP; Rabbits; Superoxides | 1995 |
Isoflurane and cytochrome b5 stimulation of 2-chloro-1,1-difluoroethene metabolism by reconstituted rat CYP2B1 and CYP2C6.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzphetamine; Chlorofluorocarbons; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Cytochromes b5; Fluorides; Isoflurane; Male; Microsomes, Liver; NADP; Phenobarbital; Rabbits; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet; Steroid 21-Hydroxylase; Steroid Hydroxylases | 1995 |
Influence of ionic strength on the P450 monooxygenase reaction and role of cytochrome b5 in the process.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzene Derivatives; Benzphetamine; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes b5; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Osmolar Concentration; Oxidoreductases; Rabbits; Steroid Hydroxylases | 1994 |
Oxygen radical formation during cytochrome P450-catalyzed cyclosporine metabolism in rat and human liver microsomes at varying hydrogen ion concentrations.
Topics: Adrenochrome; Animals; Benzphetamine; Cyclosporine; Cytochrome c Group; Cytochrome P-450 Enzyme System; Electron Transport; Epinephrine; Free Radicals; Humans; Hydrogen-Ion Concentration; Male; Malondialdehyde; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 1995 |
Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine.
Topics: Anaerobiosis; Animals; Benzphetamine; Coumarins; Cytochrome P-450 CYP2B1; Enzyme Inhibitors; Escherichia coli; Hydrogen Peroxide; Hydroxylation; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Protein Binding; Rats; Rats, Long-Evans; Testosterone; Triazoles | 2004 |
The effect of temperature on monoxygenase reactions in the microsomal membrane.
Topics: Aminopyrine; Animals; Anisoles; Benzphetamine; Catalysis; Cell Membrane; Ethylmorphine; Ethylmorphine-N-Demethylase; Glycerol; Kinetics; Male; Methylation; Microsomes; NADP; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Long-Evans; Substrate Specificity; Temperature; Time Factors | 1977 |
Cytochrome b5 increases the rate of product formation by cytochrome P450 2B4 and competes with cytochrome P450 reductase for a binding site on cytochrome P450 2B4.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzphetamine; Binding Sites; Binding, Competitive; Chromatography, Liquid; Cyclohexanols; Cytochrome P450 Family 2; Cytochromes b5; Gas Chromatography-Mass Spectrometry; Mass Spectrometry; NADP; NADPH-Ferrihemoprotein Reductase; Rabbits; Rats; Substrate Specificity | 2007 |