benzphetamine and 3-methylcholanthrene

benzphetamine has been researched along with 3-methylcholanthrene in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199032 (96.97)18.7374
1990's0 (0.00)18.2507
2000's1 (3.03)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hunter, AL; Neal, RA1
Kicha, LP; Strickhart, FS; Yang, CS1
Baird, MB; Birnbaum, LS1
Conney, AH; Kuntzman, R; Levin, W; Lu, AY; Ryan, D; Vore, M; West, SB1
Guengerich, FP1
Imai, Y; Iyanagi, T; Sato, R1
Atkinson, N; Chung, LW; French, TA; Petersen, DR1
Conney, AH; Kuntzman, R; Levin, W; Lu, AY; Ryan, D; West, Sk1
Levin, W; Lu, AY; Miwa, GT; Ryan, D; Thomas, PE; West, SB1
Levin, W; Lu, AY; Ryan, D; West, S1
Kawalek, J; Levin, L; Lu, YH; Ryan, D; West, SB1
Drew, RT; Gupta, BN; Harper, C; Talley, FA1
Holscher, M; Mgbodile, MU; Neal, RA1
Correia, MA; Mannering, GJ1
Jacobson, M; Kuntzman, R; Levin, W; Lu, AY; McCay, PB; Poyer, JL1
Neal, RA; Norman, BJ; Poore, RE1
Strickhart, FS; Yang, CS1
Conney, AH; Jacobson, M; Kuntzman, R; Levin, W; Lu, AY; Ryan, D; West, S1
Blumberg, WE; Levin, W; Lu, AY; Peisach, J; Stern, JO1
Burke, MD; Estabrook, RW; Matsubara, T; Prough, RA1
Fouts, JR; Hansen, AR1
Diaugustine, RP; Eling, TE; Fouts, JR1
Conney, AH; Jacobson, M; Kuntzman, R; Levin, W; Lu, AY; Ryan, D; West, SB1
Jacobson, M; Kuntzman, R; Levin, W; Lu, AY; West, SB1
Anders, MW1
Coon, MJ; Heidema, JK; Nebert, DW; Strobel, HW1
Chhabra, RS; Fouts, JR1
Levin, W; Lu, AY1
Fouts, JR; Kutt, H; Waters, L2
Potrepka, RF; Spratt, JL1
Delaforge, M; Ioannides, C; Parke, DV; Phillipson, CE1
Huang, M; Le, J; Peng, RX; Wang, H1

Other Studies

33 other study(ies) available for benzphetamine and 3-methylcholanthrene

ArticleYear
Inhibition of hepatic mixed-function oxidase activity in vitro and in vivo by various thiono-sulfur-containing compounds.
    Biochemical pharmacology, 1975, Dec-01, Volume: 24, Issue:23

    Topics: Animals; Benzphetamine; Cytochrome P-450 Enzyme Inhibitors; In Vitro Techniques; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Rats; Thiones; Time Factors

1975
Interaction between NADPH-cytochrome P-450 reductase and hepatic microsomes.
    Biochimica et biophysica acta, 1978, May-18, Volume: 509, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzphetamine; Catalysis; Coumarins; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Ethyl Ethers; Membrane Proteins; Methylcholanthrene; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Oxygenases; Phenobarbital; Rats

1978
Induction of hepatic mixed function oxidases in senescent rodents.
    Experimental gerontology, 1978, Volume: 13, Issue:5

    Topics: Aging; Animals; Benzopyrene Hydroxylase; Benzphetamine; Biotransformation; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Ethylmorphine-N-Demethylase; Liver; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Phenobarbital; Pregnanolone; Rats

1978
Role of cytochrome b5 in NADPH-and NADH-dependent hydroxylation by the reconstituted cytochrome P-450- or P-448-containing system.
    Advances in experimental medicine and biology, 1975, Volume: 58, Issue:00

    Topics: Animals; Benzopyrene Hydroxylase; Benzphetamine; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Electron Transport; Hydroxylation; Lipid Metabolism; Methylcholanthrene; Microsomes, Liver; NAD; NADH, NADPH Oxidoreductases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Rats; Spectrum Analysis; Testosterone

1975
Separation and purification of multiple forms of microsomal cytochrome P-450. Activities of different forms of cytochrome P-450 towards several compounds of environmental interest.
    The Journal of biological chemistry, 1977, Jun-10, Volume: 252, Issue:11

    Topics: Aflatoxins; Animals; Benzopyrenes; Benzphetamine; Carbamates; Carcinogens; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Furans; Lung; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; p-Aminoazobenzene; p-Dimethylaminoazobenzene; Parathion; Phenobarbital; Pyrrolizidine Alkaloids; Rabbits; Rats; Terpenes; Toxins, Biological

1977
Rate-limiting step in the reconstituted microsomal drug hydroxylase system.
    Journal of biochemistry, 1977, Volume: 82, Issue:5

    Topics: Animals; Benzphetamine; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Kinetics; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Rabbits; Spectrophotometry

1977
Differential induction of hepatic microsomal ethanol and drug metabolism by 3-methylcholanthrene in "LS" and "SS" mice.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 209, Issue:3

    Topics: Alcohol Oxidoreductases; Aniline Hydroxylase; Animals; Benzopyrene Hydroxylase; Benzphetamine; Cytochromes; Enzyme Induction; Ethanol; Ethylmorphine-N-Demethylase; In Vitro Techniques; Methylcholanthrene; Mice; Microsomes, Liver; Oxidoreductases, N-Demethylating; Pharmaceutical Preparations; Protein Biosynthesis; Sleep; Species Specificity; Steroid Hydroxylases; Testosterone

1979
Partial purification and separation of multiple forms of cytochrome. P-450 and cytochrome P-448 from rat liver microsomes.
    Advances in experimental medicine and biology, 1975, Volume: 58, Issue:00

    Topics: Animals; Benzopyrenes; Benzphetamine; Carbon Monoxide; Chromatography, DEAE-Cellulose; Cytochrome P-450 Enzyme System; Cytochromes; Epoxide Hydrolases; Ethane; Lipids; Male; Methylcholanthrene; Microsomes, Liver; Multienzyme Complexes; NADPH-Ferrihemoprotein Reductase; Naphthalenes; Nitriles; Oxidation-Reduction; Phenobarbital; Phosphatidylcholines; Rats; Spectrum Analysis; Surface-Active Agents

1975
Accessibility of cytochrome P450 in microsomal membranes: inhibition of metabolism by antibodies to cytochrome P450.
    Molecular pharmacology, 1977, Volume: 13, Issue:5

    Topics: Animals; Antibodies; Benzopyrenes; Benzphetamine; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochromes; In Vitro Techniques; Male; Membranes; Methylcholanthrene; Microsomes, Liver; Morphine Derivatives; Phenobarbital; Rats; Testosterone

1977
Multiple forms of cytochrome P-450 in phenobarbital- and 3-methylcholanthrene-treated rats. Separation and spectral properties.
    The Journal of biological chemistry, 1975, Mar-25, Volume: 250, Issue:6

    Topics: Amines; Animals; Benzopyrenes; Benzphetamine; Chromatography, DEAE-Cellulose; Cyanides; Cytochrome P-450 Enzyme System; Hemeproteins; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Protein Conformation; Rats; Spectrophotometry

1975
Highly purified cytochrome P-448 and P=450 from rat liver microsomes.
    Biochemical and biophysical research communications, 1975, Jun-16, Volume: 64, Issue:4

    Topics: Animals; Benzopyrenes; Benzphetamine; Carbon Monoxide; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Methylcholanthrene; Microsomes, Liver; Molecular Weight; Oxidation-Reduction; Phenobarbital; Rats; Spectrophotometry

1975
Effects of vinyl chloride exposures to rats pretreated with phenobarbital.
    Environmental health perspectives, 1975, Volume: 11

    Topics: Animals; Benzphetamine; Body Weight; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Environmental Exposure; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Phenobarbital; Rats; Vinyl Chloride; Vinyl Compounds

1975
A possible protective role for reduced glutathione in aflatoxin B1 toxicity: effect of pretreatment of rats with phenobarbital and 3-methylcholanthrene on aflatoxin toxicity.
    Toxicology and applied pharmacology, 1975, Volume: 34, Issue:1

    Topics: Aflatoxins; Animals; Benzphetamine; Body Weight; Chemical and Drug Induced Liver Injury; Cysteine; Cytochrome P-450 Enzyme System; Drug Interactions; Glutathione; Liver; Male; Maleates; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Necrosis; Phenobarbital; Rats

1975
Reduced diphosphopyridine nucleotide synergism of the reduced triphosphopyridine nucleotide-dependent mixed-function oxidase system of hepatic microsomes. II. Role of the type I drug-binding site of cytochrome P-450.
    Molecular pharmacology, 1973, Volume: 9, Issue:4

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Codeine; Cyanides; Cytochrome P-450 Enzyme System; Drug Synergism; Female; Hydroxylation; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Morphinans; NAD; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Phospholipases; Proadifen; Protein Binding; Rats

1973
Lipid peroxidation and the degradation of cytochrome P-450 heme.
    Archives of biochemistry and biophysics, 1973, Volume: 158, Issue:2

    Topics: Aminopyrine; Animals; Benzopyrenes; Benzphetamine; Carbon Monoxide; Chromatography, Paper; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Levulinic Acids; Lipid Metabolism; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidation-Reduction; Pentobarbital; Peroxidases; Phenobarbital; Protein Binding; Rats; Secobarbital; Spectrophotometry; Time Factors; Tritium

1973
Studies of the binding of sulfur released in the mixed-function oxidase-catalyzed metabolism of diethyl p-nitrophenyl phosphorothionate(parathion) to diethyl p-nitrophenyl phosphate (paraoxon).
    Biochemical pharmacology, 1974, Jun-15, Volume: 23, Issue:12

    Topics: Animals; Benzphetamine; Carbon Monoxide; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Dealkylation; Esterases; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidoreductases; Paraoxon; Parathion; Phenobarbital; Solvents; Sulfur; Sulfur Radioisotopes

1974
Inhibition of hepatic mixed function oxidase activity by propyl gallate.
    Biochemical pharmacology, 1974, Nov-15, Volume: 23, Issue:22

    Topics: Aging; Aminopyrine N-Demethylase; Animals; Benzopyrenes; Benzphetamine; Cytochrome c Group; Cytochrome P-450 Enzyme Inhibitors; Cytochrome Reductases; Diet; Gallic Acid; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Methyltransferases; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NADP; Oxidoreductases; Phenobarbital; Rats; Spectrophotometry, Ultraviolet

1974
The role of cytochrome P-450 and P-448 in drug and steroid hydroxylations.
    Annals of the New York Academy of Sciences, 1973, Volume: 212

    Topics: Age Factors; Aniline Compounds; Animals; Benzopyrenes; Benzphetamine; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Hydroxylation; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; Morphine Derivatives; Pentobarbital; Phenobarbital; Piperazines; Rats; Testosterone

1973
A low-temperature EPR study of partially purified, soluble ferric cytochromes P-450 and P-448 from rat liver microsomes.
    Archives of biochemistry and biophysics, 1973, Volume: 156, Issue:2

    Topics: Animals; Benzopyrenes; Benzphetamine; Cytochrome P-450 Enzyme System; Cytochromes; Electron Spin Resonance Spectroscopy; Guanidines; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Spectrophotometry

1973
The preparation of microsomal fractions of rodent respiratory tract and their characterization.
    Cancer research, 1974, Volume: 34, Issue:9

    Topics: Animals; Benzopyrenes; Benzphetamine; Biphenyl Compounds; Cell Fractionation; Centrifugation; Cytochrome P-450 Enzyme System; Cytochromes; Electron Transport Complex IV; Enzyme Induction; Lung; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; NAD; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Rats; Spectrophotometry, Ultraviolet

1974
A comparison of the effects of benzypyrene administration on some hepatic microsomal mixed-function oxidases of rats and mice.
    Biochemical pharmacology, 1971, Volume: 20, Issue:11

    Topics: Aniline Compounds; Animals; Benzopyrenes; Benzphetamine; Cytochromes; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Light; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; NADP; Oxidoreductases; Rats; Rats, Inbred Strains; Spectrum Analysis

1971
The interaction of a fluorescent probe with rat hepatic microsomes.
    Chemico-biological interactions, 1970, Volume: 2, Issue:1

    Topics: Aniline Compounds; Animals; Benzphetamine; Binding Sites; Fluorometry; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Naphthalenes; Oxidoreductases; Phenobarbital; Rats; Sulfites; Sulfonic Acids; Warfarin

1970
Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. VI. Different substrate specificities of the cytochrome P450 fractions from control and phenobarbital-treated rats.
    The Journal of biological chemistry, 1973, Jan-25, Volume: 248, Issue:2

    Topics: Aniline Compounds; Animals; Benzopyrenes; Benzphetamine; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Dealkylation; Dose-Response Relationship, Drug; Flavonoids; Hemeproteins; Hydroxylation; Lipids; Male; Methylcholanthrene; Microsomes, Liver; Morphinans; Oxidoreductases, N-Demethylating; Pentobarbital; Phenobarbital; Piperazines; Proadifen; Rats; Structure-Activity Relationship; Testosterone

1973
Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. IV. Hydroxylation of aniline.
    Archives of biochemistry and biophysics, 1972, Volume: 153, Issue:1

    Topics: Acetone; Aniline Compounds; Animals; Benzopyrenes; Benzphetamine; Carbon Isotopes; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Activation; Hydroxylation; Lipids; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Spectrophotometry

1972
Effect of phenobarbital and 3-methylcholanthrene administration on the in vitro enhancement of microsomal aromatic hydroxylation.
    Archives of biochemistry and biophysics, 1972, Volume: 153, Issue:2

    Topics: Acetanilides; Acetone; Aniline Compounds; Animals; Benzphetamine; Hydroxylation; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Protein Binding; Pyridines; Rats; Spectrophotometry; Time Factors

1972
Genetic expression of aryl hydrocarbon hydroxylase induction. Genetic specificity resides in the fraction containing cytochromes P448 and P450.
    The Journal of biological chemistry, 1973, Nov-25, Volume: 248, Issue:22

    Topics: Animals; Benzopyrenes; Benzphetamine; Carcinogens; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Enzyme Induction; Flavonoids; Genetics; Humans; Hydrocarbons; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; Mixed Function Oxygenases; Naphthols; Oxidoreductases, N-Demethylating; Rats; Species Specificity

1973
Stimulation of hepatic drug-metabolizing enzymes by DDT, polycyclic hydrocarbons or phenobarbital in adrenalectomized or castrated mice.
    Toxicology and applied pharmacology, 1974, Volume: 28, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Aminopyrine N-Demethylase; Aniline Compounds; Animals; Benzopyrenes; Benzphetamine; Castration; DDT; Dealkylation; Hydrogen-Ion Concentration; Liver; Male; Methylcholanthrene; Methyltransferases; Mice; Mixed Function Oxygenases; Morphinans; Phenobarbital; Polycyclic Compounds; Proteins; Stimulation, Chemical; Testis

1974
Partial purification of cytochromes P-450 and P-448 from rat liver microsomes.
    Biochemical and biophysical research communications, 1972, Feb-16, Volume: 46, Issue:3

    Topics: Ammonium Sulfate; Animals; Benzopyrenes; Benzphetamine; Calcium Phosphates; Carbon Monoxide; Chemical Precipitation; Cytochromes; Gels; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Spectrophotometry

1972
The effects of some stimulators (inducers) of hepatic microsomal drug-metabolizing enzyme activity on substrate-induced difference spectra in rat liver microsomes.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:1

    Topics: Aniline Compounds; Animals; Benzphetamine; Carbon Isotopes; DDT; Enzyme Induction; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Spectrophotometry

1971
Diphenylhydantoin-induced difference spectra with rat-liver microsomes.
    Chemico-biological interactions, 1970, Volume: 2, Issue:3

    Topics: Animals; Benzphetamine; Chlordan; DDT; Drug Interactions; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Spectrum Analysis

1970
Effect of phenobarbital and 3-methylcholanthrene pretreatment on guinea pig hepatic microsomal bilirubin glucuronyltransferase activity.
    Biochemical pharmacology, 1971, Volume: 20, Issue:4

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Bilirubin; Cats; Colorimetry; Enzyme Activation; Glucuronates; Guinea Pigs; Kinetics; Male; Mathematics; Methylcholanthrene; Mice; Microsomes, Liver; Nucleoside Diphosphate Sugars; Phenobarbital; Rabbits; Rats; Species Specificity; Statistics as Topic; Time Factors; Transferases; Uracil Nucleotides

1971
Studies on the substrate-binding sites of liver microsomal cytochrome P-448.
    The Biochemical journal, 1982, Oct-01, Volume: 207, Issue:1

    Topics: Animals; Benzphetamine; Binding Sites; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Ellipticines; Fluorenes; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Safrole; Spectrophotometry; Substrate Specificity

1982
Influences of 3-methylcholanthrene, phenobarbital and dexamethasone on xenobiotic metabolizing-related cytochrome P450 enzymes and steroidogenesis in human fetal adrenal cortical cells.
    Acta pharmacologica Sinica, 2006, Volume: 27, Issue:8

    Topics: Adrenal Cortex; Aminopyrine N-Demethylase; Benzphetamine; Cells, Cultured; Cytochrome P-450 Enzyme System; Dexamethasone; Fetus; Humans; Methylcholanthrene; Phenobarbital; Pregnenediones; Xenobiotics

2006