Page last updated: 2024-09-02

benzoylnorecgonine and cocaine

benzoylnorecgonine has been researched along with cocaine in 18 studies

Compound Research Comparison

Studies
(benzoylnorecgonine)
Trials
(benzoylnorecgonine)
Recent Studies (post-2010)
(benzoylnorecgonine)
Studies
(cocaine)
Trials
(cocaine)
Recent Studies (post-2010) (cocaine)
200132,4611,0969,400

Protein Interaction Comparison

ProteinTaxonomybenzoylnorecgonine (IC50)cocaine (IC50)
Amyloid-beta precursor proteinHomo sapiens (human)0.338
Fatty acid-binding protein, heartHomo sapiens (human)0.367
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0855
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0855
DRattus norvegicus (Norway rat)5.7544
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)5.7544
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)5.7544
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)5.7544
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.2861
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.4321
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0855
Sodium-dependent serotonin transporterHomo sapiens (human)0.5442
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.8885
Sodium-dependent dopamine transporter Homo sapiens (human)0.3796
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)5.541
Sodium-dependent dopamine transporterMus musculus (house mouse)0.2
Sigma non-opioid intracellular receptor 1Homo sapiens (human)1.05
TransporterRattus norvegicus (Norway rat)3.2277

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's12 (66.67)18.2507
2000's2 (11.11)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alluri, VR; Giri, VV; Misra, AL; Mule, SJ; Patel, MN; Pontani, RB1
Bosron, WF; Dean, RA; Dumaual, N; Harper, ET; Stoeckel, DA1
de Zeeuw, RA; Ensing, JG; Racamy, C1
Olsen, GD; Sandberg, JA3
Falk, JL; Lau, CE; Ma, F1
Lampert, BM; Stewart, JT1
Dempsey, DA; Ferriero, DM; Konkol, RJ; Murphey, LJ; Olsen, GD1
Konkol, RJ; Murphey, LJ; Olsen, GD1
Konkol, RJ; Kron, JE; Olsen, GD1
Logan, BK; Smirnow, D1
Lau, CE; Ma, F; Zhang, J1
Breen, P; Gurley, BJ; Light, KE; Nyamweya, NN1
Czarny, R; Klette, KL; Lau, CO; Poch, GK1
Klette, KL; Reda, LJ; Robandt, PP1
Cone, EJ; Darwin, WD; Huestis, MA; Paul, BD; Shimomura, E; Smith, ML1
Cela, R; González-Mariño, I; Quintana, JB; Rodríguez, I; Sánchez-Méndez, N1

Reviews

1 review(s) available for benzoylnorecgonine and cocaine

ArticleYear
Cocaine metabolites in the neonate: potential for toxicity.
    Journal of child neurology, 1994, Volume: 9, Issue:3

    Topics: Butyrylcholinesterase; Central Nervous System Diseases; Cocaine; Female; Fetal Blood; Fever; Humans; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Neonatal Abstinence Syndrome; Pregnancy; Prospective Studies; Respiratory Distress Syndrome, Newborn

1994

Other Studies

17 other study(ies) available for benzoylnorecgonine and cocaine

ArticleYear
Disposition of (3H) benzoylnorecgonine (cocaine metabolite) in the rat.
    Research communications in chemical pathology and pharmacology, 1976, Volume: 13, Issue:4

    Topics: Animals; Brain Chemistry; Cocaine; Feces; Male; Rats; Time Factors

1976
Effects of ethanol on cocaine metabolism: formation of cocaethylene and norcocaethylene.
    Toxicology and applied pharmacology, 1992, Volume: 117, Issue:1

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Cocaine; Ethanol; Injections, Intraperitoneal; Liver; Male; Rats; Rats, Wistar; Time Factors

1992
A rapid gas chromatographic method for the fingerprinting of illicit cocaine samples.
    Journal of forensic sciences, 1992, Volume: 37, Issue:2

    Topics: Bridged Bicyclo Compounds; Chromatography, Gas; Cocaine; Cyclobutanes; Illicit Drugs; Time Factors

1992
Cocaine and metabolite concentrations in the fetal guinea pig after chronic maternal cocaine administration.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Amniotic Fluid; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Cocaine; Female; Fetal Blood; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Lidocaine; Maternal-Fetal Exchange; Pregnancy

1992
Cocaine pharmacokinetics in the pregnant guinea pig.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:2

    Topics: Animals; Cocaine; Female; Guinea Pigs; Metabolic Clearance Rate; Pregnancy; Pregnancy, Animal

1991
Simultaneous determination of cocaine and its metabolites with caffeine in rat serum microsamples by high-performance liquid chromatography.
    Journal of chromatography, 1990, Oct-26, Volume: 532, Issue:1

    Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Cocaine; Drug Stability; Male; Microchemistry; Rats

1990
Microassay for the simultaneous determination of cocaine, norcocaine, benzoylecgonine and benzoylnorecgonine by high-performance liquid chromatography.
    Journal of chromatography, 1990, Jan-26, Volume: 525, Issue:1

    Topics: Amniotic Fluid; Animals; Chromatography, High Pressure Liquid; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Maternal-Fetal Exchange; Pregnancy

1990
Determination of cocaine and selected metabolites in canine and human serum by reversed-phase high-performance liquid chromatography on coupled cyanopropyl and silica columns.
    Journal of chromatography, 1989, Oct-27, Volume: 495

    Topics: Animals; Chromatography, High Pressure Liquid; Cocaine; Dogs; Humans; Spectrophotometry, Ultraviolet

1989
Quantitation of benzoylnorecgonine and other cocaine metabolites in meconium by high-performance liquid chromatography.
    Journal of chromatography, 1993, Apr-02, Volume: 613, Issue:2

    Topics: Chromatography, High Pressure Liquid; Cocaine; Female; Humans; Infant, Newborn; Meconium; Pregnancy; Substance-Related Disorders

1993
In vivo pharmacokinetics and in vitro production of cocaethylene in pregnant guinea pigs.
    Life sciences, 1996, Volume: 58, Issue:20

    Topics: Animals; Chromatography, High Pressure Liquid; Cocaine; Ethanol; Female; Mice; Microsomes, Liver; Pregnancy

1996
Analysis of ecgonine and other cocaine biotransformation products in postmortem whole blood by protein precipitation-extractive alkylation and GC-MS.
    Journal of analytical toxicology, 1996, Volume: 20, Issue:6

    Topics: Alkylation; Amines; Biotransformation; Carboxylic Acids; Cocaine; Esterification; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Reference Standards; Solvents; Structure-Activity Relationship

1996
Determination of cocaine and its metabolites in serum microsamples by high-performance liquid chromatography and its application to pharmacokinetics in rats.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Jun-06, Volume: 693, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Cocaine; Male; Narcotics; Rats; Rats, Sprague-Dawley

1997
Pharmacokinetics of cocaine and metabolites following intragastric administration to ten-day-old rat pups.
    Pharmaceutical research, 1998, Volume: 15, Issue:3

    Topics: Administration, Oral; Animals; Animals, Newborn; Area Under Curve; Cocaine; Dietary Fats; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Rats; Rats, Sprague-Dawley

1998
Simultaneous GC-MS analysis of meta- and para-hydroxybenzoylecgonine and norbenzoylecgonine: a secondary method to corroborate cocaine ingestion using nonhydrolytic metabolites.
    Journal of analytical toxicology, 2000, Volume: 24, Issue:7

    Topics: Cocaine; Cocaine-Related Disorders; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Substance Abuse Detection

2000
Complete automation of solid-phase extraction with subsequent liquid chromatography-tandem mass spectrometry for the quantification of benzoylecgonine, m-hydroxybenzoylecgonine, p-hydroxybenzoylecgonine, and norbenzoylecgonine in urine--application to a h
    Journal of analytical toxicology, 2008, Volume: 32, Issue:8

    Topics: Automation; Chromatography, Liquid; Cocaine; Humans; Solid Phase Extraction; Tandem Mass Spectrometry

2008
Urinary excretion of ecgonine and five other cocaine metabolites following controlled oral, intravenous, intranasal, and smoked administration of cocaine.
    Journal of analytical toxicology, 2010, Volume: 34, Issue:2

    Topics: Adult; Biomarkers; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Male; Substance Abuse Detection

2010
Transformation of cocaine during water chlorination.
    Analytical and bioanalytical chemistry, 2012, Volume: 404, Issue:10

    Topics: Bromides; Chlorine; Chromatography, Liquid; Cocaine; Disinfectants; Drinking Water; Halogenation; Humans; Hydrogen-Ion Concentration; Mass Spectrometry; Water Purification

2012