Compounds > benzoxazoles
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benzoxazoles and zidovudine

benzoxazoles has been researched along with zidovudine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (87.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Emini, EA; Goldman, ME; Hoffman, JM; Nunberg, JH; O'Brien, JA; Quintero, JC; Ruffing, TL; Schleif, WA; Siegl, PK; Smith, AM1
Anderson, KW; Bakshi, KK; Durr, S; Göhler, R; Kober, A; Massari, FE; Schneider, CL; Staszewski, S; Taylor, VI; Waterbury, JA1
Chen, S; Chopra, P; Emini, EA; Hahn, BH; Kappes, JC; McFarland, R; Piatak, M; Saag, MS; Shaw, GM; Yang, LC1
Byrnes, VW; Douglas, J; Emini, EA; Hildebrand, C; Kappes, JC; Lapidus, WI; Laskin, OL; Saag, MS; Schleif, WA; Whitley, RJ1
Davey, RT; Dewar, RL; Falloon, J; Haneiwich, SE; Kovacs, JA; Masur, H; Polis, MA; Reed, GF; Vasudevachari, MB; Walker, RE1
Blaschke, T; Campbell, TB; Collier, A; Kahn, J; Kuritzkes, DR; Messari, F; Phair, J; Pottage, JC; Rosandich, ME; Schooley, RT; Stein, DS1
Baumberger, C; Hirschel, B; Kinloch-de Loës, S; Pechère, M; Perrin, L; Rakik, A; Yerly, S1
Akbay, A; Aki-Sener, E; Oren, I; Temiz-Arpaci, O; Yalçin, I1

Trials

5 trial(s) available for benzoxazoles and zidovudine

ArticleYear
Combination therapy with zidovudine prevents selection of human immunodeficiency virus type 1 variants expressing high-level resistance to L-697,661, a nonnucleoside reverse transcriptase inhibitor.
    The Journal of infectious diseases, 1995, Volume: 171, Issue:5

    Topics: Adult; Antiviral Agents; Base Sequence; Benzoxazoles; CD4 Lymphocyte Count; Double-Blind Method; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Molecular Sequence Data; Mutation; Pyridones; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Zidovudine

1995
Assessment of antiretroviral therapy by plasma viral load testing: standard and ICD HIV-1 p24 antigen and viral RNA (QC-PCR) assays compared.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Oct-01, Volume: 10, Issue:2

    Topics: Antiviral Agents; Benzoxazoles; Biomarkers; CD4 Lymphocyte Count; Double-Blind Method; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Immunoassay; Polymerase Chain Reaction; Prospective Studies; Pyridones; Reverse Transcriptase Inhibitors; RNA, Viral; Viremia; Zidovudine

1995
A short-term clinical evaluation of L-697,661, a non-nucleoside inhibitor of HIV-1 reverse transcriptase. L-697,661 Working Group.
    The New England journal of medicine, 1993, Oct-07, Volume: 329, Issue:15

    Topics: Adult; Antiviral Agents; Base Sequence; Benzoxazoles; CD4-Positive T-Lymphocytes; DNA, Viral; Double-Blind Method; Female; Follow-Up Studies; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Leukocyte Count; Male; Molecular Sequence Data; Pyridones; Reverse Transcriptase Inhibitors; Zidovudine

1993
Plasma viremia as a sensitive indicator of the antiretroviral activity of L-697,661.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jun-15, Volume: 90, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Benzoxazoles; beta 2-Microglobulin; Biomarkers; CD4 Antigens; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; HIV Core Protein p24; HIV Seropositivity; HIV-1; Humans; Male; Neoplasms; Pyridones; Time Factors; Viremia; Zidovudine

1993
Phase 1 study of combination therapy with L-697,661 and zidovudine. The ACTG 184 Protocol Team.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Aug-01, Volume: 12, Issue:4

    Topics: Adult; Antipyrine; Antiviral Agents; Base Sequence; Benzoxazoles; Cross-Over Studies; DNA Primers; DNA, Viral; Drug Interactions; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genes, pol; Genotype; HIV Seropositivity; HIV-1; Humans; Male; Molecular Sequence Data; Pilot Projects; Pyridones; Reverse Transcriptase Inhibitors; Zidovudine

1996

Other Studies

3 other study(ies) available for benzoxazoles and zidovudine

ArticleYear
L-696,229 specifically inhibits human immunodeficiency virus type 1 reverse transcriptase and possesses antiviral activity in vitro.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:5

    Topics: Benzoxazoles; Cells, Cultured; Dideoxynucleotides; Dose-Response Relationship, Drug; HIV-1; Proteins; Pyridones; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine

1992
Combined therapy with zidovudine and L-697,661 in primary HIV infection.
    AIDS (London, England), 1996, Volume: 10, Issue:11

    Topics: Adult; Anti-HIV Agents; Benzoxazoles; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; DNA, Viral; Drug Therapy, Combination; HIV Infections; Humans; Pyridones; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Viremia; Zidovudine

1996
Synthesis and HIV-1 reverse transcriptase inhibitor activity of some 2,5,6-substituted benzoxazole, benzimidazole, benzothiazole and oxazolo(4,5-b)pyridine derivatives.
    Arzneimittel-Forschung, 2003, Volume: 53, Issue:4

    Topics: Benzimidazoles; Benzoxazoles; Dideoxynucleotides; HIV Reverse Transcriptase; Indicators and Reagents; Magnetic Resonance Spectroscopy; Pyridines; Reverse Transcriptase Inhibitors; Spectrophotometry, Infrared; Thiazoles; Thymidine; Thymine Nucleotides; Zidovudine

2003