Compounds > benzoxazoles
Page last updated: 2024-08-21

benzoxazoles and leucine

benzoxazoles has been researched along with leucine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's0 (0.00)29.6817
2010's6 (54.55)24.3611
2020's4 (36.36)2.80

Authors

AuthorsStudies
Evans, DB; Fan, N; Rank, KB; Sharma, SK; Tarpley, WG; Thomas, RC1
Anzai, N; Endo, H; Endou, H; Hosoda, N; Kanai, Y; Oda, K; Saito, K; Sakata, T; Tsujihara, K; Wempe, MF; Yamamura, M1
Chun, HS; Endou, H; Kanai, Y; Kim, CS; Kim, DK; Kim, HJ; Kim, JS; Kim, SG; Lee, SA; Oh, JS; Park, MG; Park, MR; Wempe, MF; Yu, SK; Yun, DW1
Endou, H; Kawada, A; Kimura, T; Ochiai, T; Sakurai, H; Ueno, S; Yamaga, T1
Anzai, N; Chida, M; Endou, H; Fujita, T; Hayashi, K; Jutabha, P; Maeda, S; Ouchi, M; Supak, Y1
Anzai, N; Dokduang, H; Endou, H; Hayashi, K; Jutabha, P; Loilome, W; Namwat, N; Sangkhamanon, S; Yongvanit, P; Yothaisong, S1
Akosman, I; Dosier, LBM; McMahon, TJ; Premkumar, VJ; Wempe, MF; Zhu, H1
Björkenheim, A; Szabó, B; Sztaniszláv, ÁJ1
Cronk, S; Dinara, S; Ikhlef, H; Massaro, C; Moots, H; Phanstiel, O; Thomas, J1
Huttunen, J; Huttunen, KM; Markowicz-Piasecka, M; Montaser, A1
Anzai, N; Furihata, T; Higuchi, K; Kaneko, M; Morio, H; Muto, Y; Nakagawa, K; Ohno, Y; Okunushi, K; Otsuka, Y; Reien, Y; Sakamoto, S; Shimojo, N; Wakashin, H; Watanabe, Y1

Other Studies

11 other study(ies) available for benzoxazoles and leucine

ArticleYear
Mechanism of resistance to U-90152S and sensitization to L-697,661 by a proline to leucine change at residue 236 of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.
    FEBS letters, 1995, Feb-13, Volume: 359, Issue:2-3

    Topics: Amino Acid Sequence; Antiviral Agents; Base Sequence; Benzoxazoles; Delavirdine; DNA Primers; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Indoles; Leucine; Molecular Sequence Data; Piperazines; Point Mutation; Proline; Pyridones; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase

1995
L-type amino acid transporter 1 inhibitors inhibit tumor cell growth.
    Cancer science, 2010, Volume: 101, Issue:1

    Topics: Amino Acid Transport System y+; Animals; Antineoplastic Agents; Benzoxazoles; Cell Proliferation; Fusion Regulatory Protein 1, Light Chains; HT29 Cells; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Large Neutral Amino Acid-Transporter 1; Leucine; Male; Mice; Mice, Inbred BALB C; Protein Serine-Threonine Kinases; TOR Serine-Threonine Kinases; Tyrosine; Xenograft Model Antitumor Assays

2010
JPH203, an L-type amino acid transporter 1-selective compound, induces apoptosis of YD-38 human oral cancer cells.
    Journal of pharmacological sciences, 2014, Volume: 124, Issue:2

    Topics: Amino Acid Transport System L; Antineoplastic Agents; Apoptosis; Benzoxazoles; Caspases; Fusion Regulatory Protein 1, Heavy Chain; Humans; Large Neutral Amino Acid-Transporter 1; Leucine; Mouth Neoplasms; Tumor Cells, Cultured; Tyrosine; Up-Regulation

2014
Metformin enhances anti-tumor effect of L-type amino acid transporter 1 (LAT1) inhibitor.
    Journal of pharmacological sciences, 2016, Volume: 131, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoxazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Hypoglycemic Agents; Large Neutral Amino Acid-Transporter 1; Leucine; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice, Inbred BALB C; Mice, Nude; Multiprotein Complexes; TOR Serine-Threonine Kinases; Tyrosine

2016
LAT1 acts as a crucial transporter of amino acids in human thymic carcinoma cells.
    Journal of pharmacological sciences, 2016, Volume: 132, Issue:3

    Topics: Amino Acids; Benzoxazoles; Cell Line, Tumor; Humans; Large Neutral Amino Acid-Transporter 1; Leucine; Thymoma; Thymus Neoplasms; Tyrosine

2016
Inhibition of l-type amino acid transporter 1 activity as a new therapeutic target for cholangiocarcinoma treatment.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, Volume: 39, Issue:3

    Topics: Animals; Apoptosis; Benzoxazoles; Cell Line, Tumor; Cell Proliferation; Cholangiocarcinoma; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Large Neutral Amino Acid-Transporter 1; Leucine; Mice; Molecular Targeted Therapy; Tyrosine; Xenograft Model Antitumor Assays

2017
Antagonists of the system L neutral amino acid transporter (LAT) promote endothelial adhesivity of human red blood cells.
    Thrombosis and haemostasis, 2017, 06-28, Volume: 117, Issue:7

    Topics: Amino Acid Transport System L; Amino Acids, Cyclic; Animals; Benzoxazoles; Cell Adhesion; Cysteine; Endothelial Cells; Erythrocyte Deformability; Erythrocytes; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Leucine; Mice; Mice, Nude; Reticulocytes; RNA, Messenger; S-Nitrosothiols; Tyrosine

2017
Hereditary transthyretin amyloidosis caused by the rare Phe33Leu mutation.
    BMJ case reports, 2020, Jan-12, Volume: 13, Issue:1

    Topics: Amyloid Neuropathies, Familial; Benzoxazoles; Combined Modality Therapy; Diagnosis, Differential; Heart Transplantation; Humans; Leucine; Male; Middle Aged; Mutation; Phenylalanine; Prealbumin

2020
Serendipitous Discovery of Leucine and Methionine Depletion Agents during the Search for Polyamine Transport Inhibitors.
    Journal of medicinal chemistry, 2020, 03-26, Volume: 63, Issue:6

    Topics: Animals; Benzoxazoles; Biological Transport; CHO Cells; Cricetulus; Drug Discovery; Humans; Large Neutral Amino Acid-Transporter 1; Leucine; Methionine; Polyamines; Putrescine; Small Molecule Libraries; Spermidine; Spermine; Tyrosine

2020
Hemocompatible LAT1-inhibitor can induce apoptosis in cancer cells without affecting brain amino acid homeostasis.
    Apoptosis : an international journal on programmed cell death, 2020, Volume: 25, Issue:5-6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzoxazoles; Brain; Brain Chemistry; Carboxylic Acids; Drug Synergism; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Injections, Intraperitoneal; Large Neutral Amino Acid-Transporter 1; Leucine; Male; MCF-7 Cells; Mice; Myocytes, Smooth Muscle; NF-kappa B; Norbornanes; Primary Cell Culture; Pyridines; Signal Transduction; Thiazoles; TOR Serine-Threonine Kinases; Tyrosine

2020
JPH203, a newly developed anti-cancer drug, shows a preincubation inhibitory effect on L-type amino acid transporter 1 function.
    Journal of pharmacological sciences, 2020, Volume: 144, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents; Benzoxazoles; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Large Neutral Amino Acid-Transporter 1; Leucine; Time Factors; Tyrosine

2020