Page last updated: 2024-08-21

benzoxazoles and indazoles

benzoxazoles has been researched along with indazoles in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berthelot, D; Bischoff, F; Borghys, H; De Cleyn, M; Gijsen, HJ; Macdonald, G; Masungi, C; Mercken, M; Minne, G; Oehlrich, D; Pieters, S; Surkyn, M; Trabanco, AA; Tresadern, G; Van Brandt, S; Velter, I; Zaja, M1
Civiello, RL; Conway, CM; Cook, DA; Davis, CD; Degnan, AP; Dubowchik, GM; Han, X; Jiang, XJ; Macci, R; Macor, JE; Mathias, NR; Moench, P; Pin, SS; Schartman, R; Signor, LJ; Thalody, G; Tora, G; Whiterock, V; Xu, C1
Adachi, R; Amano, N; Hidaka, K; Ishii, T; Kamaura, M; Kitazaki, T; Kubo, O; Maki, T; Mochida, T; Morimoto, S; Nakakariya, M; Sato, K; Takahagi, H; Takai, T; Takekawa, S; Yoshikawa, T1
Beaufils, B; Binnie, M; Bouillot, A; Denis, AA; Hann, MM; Haslam, CP; Holmes, DS; Hutchinson, JP; Kranz, M; Liddle, J; McBride, A; Mirguet, O; Mole, DJ; Mowat, CG; Pal, S; Rowland, P; Trottet, L; Uings, IJ; Walker, AL; Webster, SP1
Bernards, R; Caumanns, JJ; de Jong, S; Jalving, M; Kol, A; Meersma, GJ; van der Zee, AGJ; van Wijngaarden, A; Wisman, GBA1

Other Studies

5 other study(ies) available for benzoxazoles and indazoles

ArticleYear
Design and synthesis of a novel series of bicyclic heterocycles as potent γ-secretase modulators.
    Journal of medicinal chemistry, 2012, Nov-08, Volume: 55, Issue:21

    Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Benzimidazoles; Benzoxazoles; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Dogs; Drug Design; Humans; Imidazoles; Indazoles; Male; Mice; Microsomes, Liver; Molecular Conformation; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley

2012
The synthesis and SAR of calcitonin gene-related peptide (CGRP) receptor antagonists derived from tyrosine surrogates. Part 2.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Administration, Intranasal; Amino Acids; Animals; Benzoxazoles; Biological Availability; Calcitonin Gene-Related Peptide Receptor Antagonists; Half-Life; Indazoles; Protein Binding; Quinazolinones; Rabbits; Receptors, Calcitonin Gene-Related Peptide; Structure-Activity Relationship; Tyrosine

2013
Discovery of a Novel Series of N-Phenylindoline-5-sulfonamide Derivatives as Potent, Selective, and Orally Bioavailable Acyl CoA:Monoacylglycerol Acyltransferase-2 Inhibitors.
    Journal of medicinal chemistry, 2015, May-14, Volume: 58, Issue:9

    Topics: Acyltransferases; Administration, Oral; Animals; Benzimidazoles; Benzoxazoles; Biological Availability; Cell Line; Humans; Indazoles; Indoles; Male; Mice, Inbred C57BL; Microsomes, Liver; Structure-Activity Relationship; Sulfonamides; Triglycerides

2015
The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis.
    Bioorganic & medicinal chemistry letters, 2017, 05-01, Volume: 27, Issue:9

    Topics: Animals; Benzoxazoles; Drug Discovery; Enzyme Inhibitors; HEK293 Cells; Humans; Indazoles; Kynurenine; Kynurenine 3-Monooxygenase; Pancreatitis; Rats; Tryptophan

2017
Low-dose triple drug combination targeting the PI3K/AKT/mTOR pathway and the MAPK pathway is an effective approach in ovarian clear cell carcinoma.
    Cancer letters, 2019, Oct-01, Volume: 461

    Topics: Adenocarcinoma, Clear Cell; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzimidazoles; Benzoxazoles; Biomarkers, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Indazoles; Mice; Mice, Nude; Morpholines; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidines; Sulfonamides; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019