benzoxazoles has been researched along with benzoxazolone in 120 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (12.50) | 18.7374 |
| 1990's | 3 (2.50) | 18.2507 |
| 2000's | 41 (34.17) | 29.6817 |
| 2010's | 45 (37.50) | 24.3611 |
| 2020's | 16 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Flaim, KE; Franz, RG; Gaitanopoulos, DE; Gessner, G; Hieble, JP; Kinter, LB; Mann, WA; Stringer, OD; Weinstock, J | 1 |
| Calcaterra, NB; Niemeyer, HM; Roveri, OA | 1 |
| Cîrje, M; Cîrstea, M; Mihăileanu, M; Petec, G; Suhaciu, G; Vacariu, A | 1 |
| Kleinrok, Z; Kolasa, K; Rajtar, G | 1 |
| Bergon, M; Vigroux, A; Zedde, C | 1 |
| Demirdamar, R; Erol, DD | 1 |
| Kapil, A; Sharma, S; Wahidulla, S | 1 |
| Bacon, CW; Glenn, AE; Hinton, DM; Yates, IE | 1 |
| Hennig, L; Knop, M; Schneider, B; Schulz, M; Sicker, D | 1 |
| Bigler, L; Drandarov, K; Hesse, M; Werner, C; Zikmundová, M | 1 |
| Bacon, CW; Glenn, AE; Meredith, FI; Morrison, WH | 1 |
| Carrera, C; Macias, FA; Marin, D; Molinillo, JM; Oliveros-Bastidas, A; Simonet, AM; Varela, RM | 1 |
| LESPAGNOL, C; MERCIER, J; SESTIER, MR | 1 |
| LESPAGNOL, A; LESPAGNOL, C; MERCIER, J | 1 |
| LESPAGNOL, A; ROMAIN, M | 1 |
| DEBELMAS, J; LESPAGNOL, C | 1 |
| LESPAGNOL, C; ROBELET, A; TUDO, M | 1 |
| BUTAEYE, P; LESPAGNOL, A; LESPAGNOL, C; WAREMBOURG, H | 1 |
| BRAY, HG; CLOWES, RC; THORPE, WV | 1 |
| Belz, RG; Hurle, K | 1 |
| Burgos, NR; Kim, KS; Kuk, YI; Talbert, RE | 1 |
| Chiapusio, G; Gallet, C; Pellissier, F | 1 |
| Ahmad Khan, N; Hejaz Azmi, SN; Rahman, N | 1 |
| Andreu, F; Courtois, M; Mincheva, Z; Rideau, M; Viaud-Massuard, MC | 1 |
| Castellano, D; Macías, FA; Marín, D; Molinillo, JM; Oliveros-Bastidas, A; Simonet, AM | 1 |
| Burton, JD; Danehower, DA; Finney, MM | 1 |
| Agarwal, AK; Baerson, SR; Duke, SO; Kagan, IA; Pedrol-Bonjoch, N; Reigosa, MJ; Sánchez-Moreiras, A; Schulz, M | 1 |
| Carato, P; Colacino, E; Poupaert, J; Yous, S | 1 |
| Christophersen, C; Fomsgaard, IS; Gents, MB; Mortensen, AG; Nielsen, ST | 1 |
| Fomsgaard, IS; Hansen, HC; Ravnskov, S; Understrup, AG | 1 |
| Bas, M; Pabuccuoglu, A; Pabuccuoglu, V; Soyer, Z | 1 |
| Reigosa, MJ; Sánchez-Moreiras, AM | 1 |
| Buckheit, RW; Cullen, MD; Cushman, M; De Clercq, E; Deng, BL; Fanwick, PE; Hartman, TL; Pannecouque, C; Zhou, Z | 1 |
| Hao, H; Hennig, L; Hofmann, D; Knop, M; Schulz, M; Sicker, D | 1 |
| Kus, J; Martyniuk, S; Oleszek, W; Stochmal, A | 1 |
| Macías, FA; Marín, D; Martyniuk, S; Oleszek, W; Stochmal, A | 1 |
| Jia, C; Kudsk, P; Mathiassen, SK | 1 |
| Kudsk, P; Mathiassen, SK; Mogensen, BB | 1 |
| Blümel, S; Coja, T; Fomsgaard, IS; Idinger, J; Mortensen, AG | 1 |
| Blümel, S; Coja, T; Idinger, J | 1 |
| Braun, R; Fritz, JI | 1 |
| Benfenati, E; Fratev, F; Fritz, JI; Lemke, F; Lo Piparo, E; Mazzatorta, P; Smiesko, M | 1 |
| Feenstra, RW; Glennon, JC; Hesselink, MB; Long, SK; McCreary, AC; Reinders, JH; Ronken, E; Van Der Neut, M; Van Scharrenburg, G | 1 |
| Buettelmann, B; Ceccarelli, SM; Huwyler, J; Jaeschke, G; Kolczewski, S; Peters, JU; Porter, R; Prinssen, E; Spooren, W; Vieira, E | 1 |
| Kant, S; Kirchmair, M; Knop, M; Müllenborn, C; Pacyna, S; Scherer, HW; Schulz, M; Steiner, U; Voloshchuk, N | 1 |
| Aktay, G; Gökhan-Kelekçi, N; Göktaş, O; Işik, S; Kiliç, E; Köysal, Y; Ozalp, M; Salgin-Gökşen, U | 1 |
| Bacon, CW; Glenn, AE; Hinton, DM; Macías, FA; Marin, D | 1 |
| Barceló, D; Eljarrat, E; Guillamón, M; Navarro, A; Villagrasa, M | 1 |
| BRAY, HG; JAMES, SP; THORPE, WV | 1 |
| CLOSE, WJ; SPIELMAN, MA; TIFFANY, BD | 1 |
| Azzolina, O; Collina, S; Florio, C; Grazia Mamolo, M; Laurini, E; Rossi, D; Vio, L; Zampieri, D; Zanette, C | 1 |
| de la Peña, TC; Reigosa, MJ; Sánchez-Moreiras, AM | 1 |
| CHECHAK, AJ; MacDONALD, SF | 1 |
| Aktay, G; Erdoğan, H; Gökhan-Kelekçi, N; Köksal, M; Unüvar, S | 1 |
| Kohn, LM; Saunders, M | 1 |
| Bacon, CW; Glenn, AE | 1 |
| González, L; Pedrol, N; Reigosa, MJ; Sánchez-Moreiras, AM | 1 |
| Berthelot, P; Carato, P; Hammoudi, F; Lebegue, N; Martin-Nizard, F; Yekini, I; Yous, S | 1 |
| Porzelle, A; Tomkinson, NC; Woodrow, MD | 1 |
| Oliveros-Bastidas, A; Reigosa, MJ; Sánchez-Moreiras, AM | 1 |
| Bradford, AM; Brown, F; Flynn, ST; Forbes, IT; Gartlon, JE; Garzya, V; Johnson, DJ; Lucas, AJ; Mookherjee, CR; Mudhar, HS; Murkitt, GS; Smith, PW; Stevenson, GI; Walker, GR; Watson, JM; Watson, SP; Wyman, PA | 1 |
| Bucala, R; Cournia, Z; Du, X; Gandavadi, S; Hare, AA; Jorgensen, WL; Leng, L | 1 |
| LESPAGNOL, A | 1 |
| Martínez-Peñalver, A; Reigosa, MJ; Sánchez-Moreiras, AM | 1 |
| Hussain, MI; Reigosa, MJ | 1 |
| Chiapusio, G; González, L; Hussain, MI; Reigosa, MJ | 1 |
| Jiang, J; Lazarus, MB; Pasquina, L; Sliz, P; Walker, S | 1 |
| Feussner, I; Gatz, C; Iven, T; Köster, J; Kruse, K; Meier, A; Thurow, C | 1 |
| Marocco, A; Schulz, M; Tabaglio, V | 1 |
| Baba, S; Fukaya, T; Ishiyama, T; Kakuyama, H; Kodo, T; Masumoto, S; Nishikawa, H | 1 |
| Batish, DR; Chum, M; Kohli, RK; Singh, HP | 1 |
| Ercan, A; Gökhan-Kelekçi, N; Salgin-Gökşen, U; Uçar, G; Yabanoğlu-Çiftçi, S; Yelekçi, K | 1 |
| Civiello, RL; Conway, CM; Cook, DA; Davis, CD; Degnan, AP; Dubowchik, GM; Han, X; Jiang, XJ; Macci, R; Macor, JE; Mathias, NR; Moench, P; Pin, SS; Schartman, R; Signor, LJ; Thalody, G; Tora, G; Whiterock, V; Xu, C | 1 |
| Ban, SR; Feng, XE; Li, QS; Ma, WH; Ma, YL; Tang, L | 1 |
| Baba, S; Fukaya, T; Ishiyama, T; Masumoto, S | 1 |
| Ram, RN; Soni, VK | 1 |
| Bojarski, AJ; Cagnotto, A; Intagliata, S; Kurczab, R; Modica, MN; Pittalà, V; Romeo, G; Salerno, L; Salmona, M; Siracusa, MA | 1 |
| Fujinaga, M; Hatori, A; Ji, B; Kawamura, K; Kumata, K; Mishra, AK; Ogawa, M; Shimoda, Y; Tiwari, AK; Wang, F; Xie, L; Yamasaki, T; Yui, J; Zhang, MR | 1 |
| Armirotti, A; Bach, A; Bauer, I; De Vivo, M; Girotto, S; Mengatto, L; Pagliuca, C; Piomelli, D; Pizzirani, D; Realini, N; Ribeiro, A; Summa, M | 1 |
| Ayah, E; Disko, U; Hofmann, D; Kia, SH; Marocco, A; Müllenborn, C; Paetz, C; Schneider, B; Schouten, A; Schulz, M; Tabaglio, V | 1 |
| Carato, P; Donnier-Maréchal, M; Furman, C; Le Broc, D; Melnyk, P | 1 |
| Bubna, GA; Ferrarese, Mde L; Ferrarese-Filho, O; Marchiosi, R; Parizotto, AV; Soares, AR | 1 |
| Abdelazeem, AH; Khan, SI; McCurdy, CR; Sufka, KJ; White, SW | 1 |
| Carfagna, C; Della Ca', N; Fini, F; Gabriele, B; Mancuso, R; Raut, DS | 1 |
| Bartók, T; Molnár, O; Szécsi, Á | 1 |
| Boukouvala, S; Davis, B; Garefalaki, V; Glenn, AE; Karagianni, EP; Kontomina, E; Kotseli, B; Sim, E; Tsirka, T | 1 |
| Batley, J; Benfield, AH; Carere, J; Gardiner, DM; Kazan, K; Kettle, AJ; Manners, JM | 1 |
| Bach, A; Melzig, L; Penna, I; Piomelli, D; Pizzirani, D; Realini, N; Russo, D; Scarpelli, R; Vozella, V | 1 |
| An, N; Chen, F; Li, Y; Na, W; Tan, Y; Xie, L; Yu, L; Zhang, X; Zhao, D | 1 |
| Anders, N; Colby, T; Disko, U; Filary, B; Harzen, A; Hennig, L; Hofmann, D; Kühn, S; Schmidt, J; Schulz, M; Sicker, D | 1 |
| Crommen, J; Han, H; Jiang, Z; Peng, K; Ruan, M; Wang, Q; Wu, H; Zhu, P | 1 |
| Budd, DC; Castagna, D; Jamieson, C; Macdonald, SJ; Watson, AJ | 1 |
| Davis, CB; Gao, M; Glenn, AE; Gold, SE; Mitchell, TR; Proctor, RH; Snook, ME; Stewart, JE | 1 |
| Batley, J; Carere, J; Gardiner, DM; Kazan, K; Kettle, AJ; Manners, JM | 1 |
| Kurtelius, T; Pihlava, JM | 1 |
| Apostolova, MD; Chanev, CD; Gerova, MS; Kalenderska, RB; Nikolova, RP; Petrov, OI; Radonova, EM; Rusew, RI; Shivachev, BL; Stateva, SR | 1 |
| Bhagat, S; Chadha, N; Kumari, N; Mishra, AK; Mishra, LC; Srivastava, P; Tiwari, AK | 1 |
| Beaufils, B; Binnie, M; Bouillot, A; Denis, AA; Hann, MM; Haslam, CP; Holmes, DS; Hutchinson, JP; Kranz, M; Liddle, J; McBride, A; Mirguet, O; Mole, DJ; Mowat, CG; Pal, S; Rowland, P; Trottet, L; Uings, IJ; Walker, AL; Webster, SP | 1 |
| Dong, W; Jiang, M; Liu, J; Liu, K; Ma, J; Shi, Z; Wang, F; Wu, H; Xin, F; Zhang, W | 1 |
| Disko, U; Ganimede, C; Hennig, L; Hofmann, D; Marocco, A; Mondani, L; Schackow, O; Schulz, M; Sicker, D; Siebers, M; Tabaglio, V; Yurkov, A | 1 |
| Botta, M; Fabris, D; Gamba, E; Gatto, B; Giannini, A; Kovalenko, L; Mély, Y; Mori, M; Saladini, F; Sosic, A | 1 |
| Ban, SR; Ge, R; Li, DT; Li, QS; Liang, TG; Luo, JR; Ma, YL; Tang, L; Xu, F | 1 |
| Bahadur, R; Choudhary, S; Malik, AK; Silakari, O; Singh, B; Singh, PK; Vyas, B | 1 |
| Koksal, M; Tugcu, G | 1 |
| Cao, H; Jiang, LY; Li, T; Song, LL; Wang, Y; Yang, C; Zhi, XY | 1 |
| Armirotti, A; Bertozzi, SM; Bongarzone, ER; Caputo, S; Cilibrasi, V; Di Martino, S; Lansbury, P; Liu, M; Margaroli, N; Mazzonna, M; Migliore, M; Nguyen, D; Ottonello, G; Penna, I; Pizzirani, D; Realini, N; Russo, D; Scarpelli, R; Skerlj, R; Sun, Y; Tardia, P | 1 |
| Bilginer, S; Erdal, FS; Gul, HI; Gulcin, I; Sakagami, H | 1 |
| Bilitewski, U; Kaufmann, DE; Kupiec, SR; Ramming, I; Zapol'skii, VA | 1 |
| Becer, E; Erdag, E; Kabadayı, H; Kesanli, B; Mulazim, Y; Vatansever, HS | 1 |
| Bardaweel, SK; Bilginer, S; Gul, HI; Sabbah, DA | 1 |
| Ban, SR; Ge, R; Li, QS; Liang, TG; Luo, JR; Tang, L; Wang, XY; Zhao, B | 1 |
| Ban, SR; Gao, XH; Ge, R; Li, QS; Luo, JR; Shi, XY; Tang, L; Zhao, B | 1 |
| Aksakal, F; Dogruer, DS; Ercetin, T; Erdogan, M; Gulcan, HO; Kilic, B; Sagkan, RI | 1 |
| Chen, H; Fan, Z; Lei, Y; Li, L; Liu, W; Ma, B; Ma, Z; Xu, L; Yin, Z; Zhang, X; Zhu, C | 1 |
| Korff, M; Markus, A; Ritter, N; Schepmann, D; Schreiber, JA; Seebohm, G; Wünsch, B | 1 |
| Choudhary, S; Kumar, M; Silakari, O; Verma, H | 1 |
| Carter, JW; Gordon, TR | 1 |
| Frehland, B; Markus, A; Schepmann, D; Wünsch, B | 1 |
| Frehland, B; Goerges, G; Markus, A; Schepmann, D; Schreiber, JA; Seebohm, G; Wünsch, B | 1 |
| Mall, T; Prasher, P; Sharma, M | 1 |
3 review(s) available for benzoxazoles and benzoxazolone
| Article | Year |
|---|---|
2(3H)-benzoxazolone and bioisosters as "privileged scaffold" in the design of pharmacological probes.
Topics: Benzoxazoles; Humans; Ligands; Models, Molecular; Molecular Probes; Molecular Structure | 2005 |
Development of Autotaxin Inhibitors: An Overview of the Patent and Primary Literature.
Topics: Benzoxazoles; Boronic Acids; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Phosphoric Diester Hydrolases; Structure-Activity Relationship | 2016 |
Synthesis and biological profile of benzoxazolone derivatives.
Topics: Analgesics; Benzoxazoles; Hydrophobic and Hydrophilic Interactions; Structure-Activity Relationship | 2023 |
117 other study(ies) available for benzoxazoles and benzoxazolone
| Article | Year |
|---|---|
Synthesis and evaluation of non-catechol D-1 and D-2 dopamine receptor agonists: benzimidazol-2-one, benzoxazol-2-one, and the highly potent benzothiazol-2-one 7-ethylamines.
Topics: Animals; Benzimidazoles; Benzoxazoles; Blood Pressure; Dogs; Female; In Vitro Techniques; Male; Rabbits; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Structure-Activity Relationship; Thiazoles; Vascular Resistance | 1987 |
Inhibition of energy metabolism by benzoxazolin-2-one.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Bacteria, Aerobic; Benzoxazoles; Cattle; Electron Transport; Energy Metabolism; Kinetics; Mitochondria, Heart; NAD | 1987 |
Spontaneous formation of immunogenic conjugates by a biotransformation product of sulfanilamide.
Topics: Animals; Antibodies; Antibody Formation; Antibody Specificity; Benzoxazoles; Biotransformation; Blood Proteins; Rabbits; Sulfanilamides | 1981 |
[Preliminary pharmacological studies on the central action of phenyl- and piperidinemethyl derivatives of benzoxazolone-2].
Topics: Animals; Benzoxazoles; Body Temperature; Brain; Catalepsy; Drug Synergism; Female; Haloperidol; Hexobarbital; Humans; Mice; Mice, Inbred Strains; Motor Activity; Sleep | 1981 |
Cyclization-activated prodrugs: N-(substituted 2-hydroxyphenyl and 2-hydroxypropyl)carbamates based on ring-opened derivatives of active benzoxazolones and oxazolidinones as mutual prodrugs of acetaminophen.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Benzoxazoles; Drug Delivery Systems; Drug Stability; Humans; Hydrogen-Ion Concentration; Oxazoles; Prodrugs; Rats | 1995 |
Analgesic and antiinflammatory activity screening of 6-acyl-3-piperidinomethyl-2(3H)-benzoxazolone derivatives.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoxazoles; Female; Mice | 1994 |
Leishmanicidal activity of 2-benzoxazolinone from Acanthus illicifolius in vitro.
Topics: Animals; Antiprotozoal Agents; Benzoxazoles; Humans; India; Leishmania donovani; Plants, Medicinal | 1994 |
Detoxification of corn antimicrobial compounds as the basis for isolating Fusarium verticillioides and some other Fusarium species from corn.
Topics: Benzoxazoles; Chromatography, Thin Layer; Culture Media; Fusarium; Plant Diseases; Zea mays | 2001 |
Glycoside carbamates from benzoxazolin-2(3H)-one detoxification in extracts and exudates of corn roots.
Topics: Benzoxazoles; Carbamates; Glycosides; Inactivation, Metabolic; Plant Roots; Zea mays | 2001 |
Biotransformation of 2-benzoxazolinone and 2-hydroxy-1,4-benzoxazin-3-one by endophytic fungi isolated from Aphelandra tetragona.
Topics: Acanthaceae; Asteraceae; Benzoxazines; Benzoxazoles; Biotransformation; Hypocreales; Oxazines | 2002 |
Identification of intermediate and branch metabolites resulting from biotransformation of 2-benzoxazolinone by Fusarium verticillioides.
Topics: Aminophenols; Anti-Infective Agents; Benzoxazoles; Biotransformation; Fungal Proteins; Fusarium; Gas Chromatography-Mass Spectrometry; Plant Diseases; Zea mays | 2003 |
Allelopathy as a new strategy for sustainable ecosystems development.
Topics: Agriculture; Benzoxazines; Benzoxazoles; Conservation of Natural Resources; Ecosystem; Helianthus; Herbicides; Melilotus; Oxazines; Penicillium; Pheromones; Plant Extracts; Plant Physiological Phenomena; Plants; Triticum | 2003 |
[Comparison of the effects of coumarins and benzoxazolones on the central nervous system].
Topics: Benzoxazoles; Central Nervous System; Coumarins; Humans | 1953 |
[Study of benzoxazolone and of certain of its derivatives].
Topics: Analgesics; Anticonvulsants; Benzoxazoles; Hypnotics and Sedatives | 1953 |
[Study of the analgesic and hypnotic action of benzoxazolones].
Topics: Analgesics; Benzoxazoles; Humans; Hypnotics and Sedatives | 1953 |
[Tests for the possible anthelmintic activity of benzoxazolone derivatives].
Topics: Anthelmintics; Benzoxazoles | 1956 |
[RESEARCH ON A POSSIBLE TRANQUILIZING ACTIVITY OF BENZOXAZOLONE].
Topics: Analgesics; Analgesics, Non-Narcotic; Anticonvulsants; Antipyretics; Benzoxazoles; Central Nervous System; Hypnotics and Sedatives; Mice; Pharmacology; Research; Tranquilizing Agents | 1964 |
[Reflections on benzoxazolone].
Topics: Benzoxazoles; Heterocyclic Compounds; Humans; Hypnotics and Sedatives; Uric Acid | 1961 |
The metabolism of aminophenols, oformamidophenol, benzoxazole, 2-methyl- and 2-phenyl-benzoxazoles and benzoxazolone in the rabbit.
Topics: Aminophenols; Animals; Benzoxazoles; Phenols; Rabbits | 1952 |
A novel laboratory screening bioassay for crop seedling allelopathy.
Topics: Benzoxazoles; Biological Assay; Chlorophyll; Dose-Response Relationship, Drug; Hydroponics; Pest Control; Plant Roots; Plants, Edible; Population Dynamics; Secale; Seedlings; Sinapis; Triticum | 2004 |
Growth inhibition and root ultrastructure of cucumber seedlings exposed to allelochemicals from rye (Secale cereale).
Topics: Benzoxazines; Benzoxazoles; Cucumis sativus; Oxazines; Pheromones; Plant Extracts; Plant Roots; Secale; Seedlings | 2004 |
Uptake and translocation of phytochemical 2-benzoxazolinone (BOA) in radish seeds and seedlings.
Topics: Benzoxazoles; Biological Transport; Carbon Radioisotopes; Germination; Kinetics; Radioisotope Dilution Technique; Raphanus; Secale; Seedlings; Seeds | 2004 |
Optimized and validated spectrophotometric methods for the determination of nicorandil in drug formulations and biological fluids.
Topics: Benzoxazoles; Body Fluids; Chemistry, Pharmaceutical; Hydrazones; Nicorandil; Oxidants; Reproducibility of Results; Spectrophotometry; Sulfanilic Acids; Vasodilator Agents | 2004 |
Synthesis and biological evaluation with plant cells of new fosmidomycin analogues containing a benzoxazolone or oxazolopyridinone ring.
Topics: Benzoxazoles; Catharanthus; Cell Proliferation; Dose-Response Relationship, Drug; Fosfomycin; Molecular Structure; Oxazoles; Pyridones; Secologanin Tryptamine Alkaloids; Thiones | 2004 |
Degradation studies on benzoxazinoids. Soil degradation dynamics of (2R)-2-O-beta-D-glucopyranosyl-4-hydroxy-(2H)- 1,4-benzoxazin-3(4H)-one (DIBOA-Glc) and its degradation products, phytotoxic allelochemicals from Gramineae.
Topics: Benzoxazines; Benzoxazoles; Chromatography, High Pressure Liquid; Drug Stability; Glycosides; Oxazines; Poaceae; Soil; Soil Microbiology; Triticum | 2005 |
Gas chromatographic method for the analysis of allelopathic natural products in rye (Secale cereale L.).
Topics: 3-Hydroxybutyric Acid; Benzoxazines; Benzoxazoles; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Glucosides; Herbicides; Lactates; Oxazines; Secale | 2005 |
Detoxification and transcriptome response in Arabidopsis seedlings exposed to the allelochemical benzoxazolin-2(3H)-one.
Topics: Amino Acid Motifs; Arabidopsis; Arabidopsis Proteins; Benzoxazoles; Cell Proliferation; Dose-Response Relationship, Drug; Gene Expression Regulation, Plant; Genes, Plant; Genome, Plant; Inactivation, Metabolic; Models, Chemical; Oligonucleotide Array Sequence Analysis; Plant Roots; Proteome; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Seedlings; Time Factors; Transcription, Genetic; Xenobiotics | 2005 |
Transformation products of 2-benzoxazolinone (BOA) in soil.
Topics: Benzoxazoles; Biotransformation; Oxazines; Plant Development; Soil; Soil Pollutants | 2005 |
Biotransformation of 2-benzoxazolinone to 2-amino-(3H)-phenoxazin-3-one and 2-acetylamino-(3H)-phenoxazin-3-one in soil.
Topics: Agriculture; Benzoxazoles; Biodegradation, Environmental; Biotransformation; Fatty Acids; Half-Life; Oxazines; Pest Control; Secale; Soil Microbiology; Temperature | 2005 |
Synthesis of some 2(3H)-benzoxazolone derivatives and their in-vitro effects on human leukocyte myeloperoxidase activity.
Topics: Benzoxazoles; Enzyme Inhibitors; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Molecular Structure; Peroxidase; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship | 2005 |
Whole plant response of lettuce after root exposure to BOA (2(3H)-benzoxazolinone).
Topics: Adenosine Triphosphatases; Benzoxazoles; Fluorescence; Lactuca; Peroxidase; Photosynthesis; Plant Roots; Superoxide Dismutase; Water | 2005 |
Synthesis and anti-HIV activity of new alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTIs) incorporating benzoxazolone and benzisoxazole rings.
Topics: Animals; Anti-HIV Agents; Benzoxazoles; Cell Line; Crystallography, X-Ray; Drug Design; HIV-1; HIV-2; Humans; In Vitro Techniques; Isoxazoles; Methane; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Protein Conformation; Rats; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2006 |
Glucosides from MBOA and BOA detoxification by Zea mays and Portulaca oleracea.
Topics: Benzoxazoles; Biotransformation; Glucosides; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Portulaca; Seedlings; Zea mays | 2006 |
Concentration of benzoxazinoids in roots of field-grown wheat (Triticum aestivum L.) varieties.
Topics: Benzoxazines; Benzoxazoles; Chromatography, High Pressure Liquid; Hydroxamic Acids; Oxazines; Pheromones; Plant Roots; Triticum | 2006 |
Effects of some benzoxazinoids on in vitro growth of Cephalosporium gramineum and other fungi pathogenic to cereals and on Cephalosporium stripe of winter wheat.
Topics: Acremonium; Ascomycota; Benzoxazoles; Fungicides, Industrial; Fusarium; Plant Diseases; Soil Microbiology; Triticum | 2006 |
Joint action of benzoxazinone derivatives and phenolic acids.
Topics: Acids, Carbocyclic; Benzoxazines; Benzoxazoles; Coumaric Acids; Drug Synergism; Herbicides; Lolium; Magnoliopsida; Oxazines; Parabens; Pheromones; Propionates; Vanillic Acid | 2006 |
Herbicidal effects of soil-incorporated wheat.
Topics: Benzoxazines; Benzoxazoles; Dose-Response Relationship, Drug; Germination; Herbicides; Oxazines; Pheromones; Poaceae; Soil; Triticum | 2006 |
Transformation of benzoxazinones and derivatives and microbial activity in the test environment of soil ecotoxicological tests on Poecilus cupreus and Folsomia candida.
Topics: Animals; Arthropods; Benzoxazines; Benzoxazoles; Coleoptera; Insecticides; Oxazines; Soil Microbiology | 2006 |
Influence of the soil composition on the effects of benzoxazinoid allelochemicals on two soil nontarget organisms.
Topics: Animals; Arthropods; Benzoxazines; Benzoxazoles; Coleoptera; Insecticides; Oxazines; Pheromones; Soil | 2006 |
Ecotoxicological effects of benzoxazinone allelochemicals and their metabolites on aquatic nontarget organisms.
Topics: Aliivibrio fischeri; Animals; Benzoxazines; Benzoxazoles; Chlorophyta; Daphnia; Oxazines; Pheromones; Triticum | 2006 |
QSAR models for Daphnia magna toxicity prediction of benzoxazinone allelochemicals and their transformation products.
Topics: Animals; Benzoxazines; Benzoxazoles; Daphnia; Oxazines; Pheromones; Quantitative Structure-Activity Relationship; Triticum | 2006 |
In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone, monohydrochloride): a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist.
Topics: Animals; Benzoxazoles; Binding, Competitive; Brain; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Lisuride; Male; Molecular Structure; Parkinson Disease; Piperazines; Quinpirole; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Receptors, Dopamine D3; Recombinant Fusion Proteins; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists | 2006 |
Rational design, synthesis, and structure-activity relationship of benzoxazolones: new potent mglu5 receptor antagonists based on the fenobam structure.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzoxazoles; Drug Design; Drug Evaluation, Preclinical; Imidazoles; Models, Animal; Pharmacokinetics; Protein Binding; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Structure-Activity Relationship | 2007 |
Zea mays: benzoxazolinone detoxification under sulfur deficiency conditions--a complex allelopathic alliance including endophytic Fusarium verticillioides.
Topics: Acetamides; Acetaminophen; Benzoxazoles; Fusarium; Inactivation, Metabolic; Oxazines; Plant Roots; Seedlings; Sulfur; Zea mays | 2007 |
1-Acylthiosemicarbazides, 1,2,4-triazole-5(4H)-thiones, 1,3,4-thiadiazoles and hydrazones containing 5-methyl-2-benzoxazolinones: synthesis, analgesic-anti-inflammatory and antimicrobial activities.
Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Benzoxazoles; Crystallography, X-Ray; Edema; Hindlimb; Hydrazones; Methylation; Mice; Microbial Viability; Models, Molecular; Molecular Structure; Semicarbazides; Structure-Activity Relationship; Thiadiazoles; Triazoles | 2007 |
Interactions of Bacillus mojavensis and Fusarium verticillioides with a benzoxazolinone (BOA) and its transformation product, APO.
Topics: Bacillus; Benzoxazoles; Fungicides, Industrial; Fusarium; Molecular Structure; Oxazines; Pest Control, Biological | 2007 |
Development of a pressurized liquid extraction-solid-phase extraction followed by liquid chromatography-electrospray ionization tandem mass spectrometry method for the quantitative determination of benzoxazolinones and their degradation products in agricu
Topics: Benzoxazoles; Chromatography, High Pressure Liquid; Soil Pollutants; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
Biological deacetylation of acetamido compounds and formation of benzoxazolone.
Topics: Benzoxazoles | 1949 |
The analgesic activity of some benzoxazolone derivatives.
Topics: Analgesics; Benzoxazoles | 1949 |
Substituted benzo[d]oxazol-2(3H)-one derivatives with preference for the sigma1 binding site.
Topics: Animals; Benzoxazoles; Binding Sites; Binding, Competitive; Ligands; Rats; Rats, Sprague-Dawley; Receptors, sigma; Sigma-1 Receptor; Structure-Activity Relationship | 2009 |
The natural compound benzoxazolin-2(3H)-one selectively retards cell cycle in lettuce root meristems.
Topics: Benzoxazoles; Biological Products; Cell Cycle; Hydroxyurea; Lactuca; Microscopy, Electron, Transmission; Plant Roots; Seedlings | 2008 |
A note on the preparation of benzoxazolone and of 2,8-dihydroxynapth [1,2] oxazole.
Topics: Benzoxazoles; Humans; Oxazoles | 1948 |
Synthesis and characterization of some new 2(3H)-benzoxazolones with analgesic and antiinflammatory activities.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzoxazoles; Drug Evaluation, Preclinical; Edema; Mice; Pain; Structure-Activity Relationship | 2009 |
Evidence for alteration of fungal endophyte community assembly by host defense compounds.
Topics: Adaptation, Physiological; Benzoxazines; Benzoxazoles; Chi-Square Distribution; Fungi; Fusarium; Genotype; Host-Pathogen Interactions; Plant Leaves; Plant Roots; Zea mays | 2009 |
FDB2 encodes a member of the arylamine N-acetyltransferase family and is necessary for biotransformation of benzoxazolinones by Fusarium verticillioides.
Topics: Arylamine N-Acetyltransferase; Benzoxazoles; Biotransformation; Fusarium; Gene Library; Genes, Fungal; Nucleic Acid Hybridization; Polymerase Chain Reaction; Secale; Sequence Analysis, DNA; Triticum; Zea mays | 2009 |
2-3H-Benzoxazolinone (BOA) induces loss of salt tolerance in salt-adapted plants.
Topics: Benzoxazoles; Gene Expression Regulation, Plant; Lactuca; Salt Tolerance; Salt-Tolerant Plants; Salts | 2009 |
Antioxidant activity of benzoxazolinonic and benzothiazolinonic derivatives in the LDL oxidation model.
Topics: Animals; Antioxidants; Aorta; Benzoxazoles; Biological Assay; Cattle; Cell Survival; Endothelial Cells; L-Lactate Dehydrogenase; Lipoproteins, LDL; Oxidation-Reduction; Thiazoles | 2009 |
Synthesis of benzoxazolones from nitroarenes or aryl halides.
Topics: Benzoxazoles; Catalysis; Combinatorial Chemistry Techniques; Cyclization; Hydrocarbons, Halogenated; Molecular Structure; Nitro Compounds | 2010 |
Reduced photosynthetic activity is directly correlated with 2-(3H)-benzoxazolinone accumulation in lettuce leaves.
Topics: Benzoxazoles; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Lactuca; Photosynthesis; Plant Leaves; Spectrometry, Fluorescence; Time Factors | 2010 |
The discovery of a series of N-substituted 3-(4-piperidinyl)-1,3-benzoxazolinones and oxindoles as highly brain penetrant, selective muscarinic M1 agonists.
Topics: Animals; Benzoxazoles; Brain; Indoles; Memory Disorders; Muscarinic Agonists; Nootropic Agents; Oxindoles; Rats; Receptor, Muscarinic M1 | 2010 |
Optimization of N-benzyl-benzoxazol-2-ones as receptor antagonists of macrophage migration inhibitory factor (MIF).
Topics: Antigens, Differentiation, B-Lymphocyte; Benzoxazoles; Binding Sites; Computer Simulation; Fibroblasts; Histocompatibility Antigens Class II; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Structure, Tertiary; Receptors, Immunologic | 2010 |
Hypnotic power of substituted benzoxazolones.
Topics: Benzoxazoles; Hypnotics and Sedatives | 1945 |
Early senescence induced by 2-3H-benzoxazolinone (BOA) in Arabidopsis thaliana.
Topics: Arabidopsis; Benzoxazoles; Chlorophyll; Chlorophyll A; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Plant Leaves; Superoxides | 2011 |
Allelochemical stress inhibits growth, leaf water relations, PSII photochemistry, non-photochemical fluorescence quenching, and heat energy dissipation in three C3 perennial species.
Topics: Benzoxazoles; Carbon; Chlorophyll; Cinnamates; Fluorescence; Hot Temperature; Osmosis; Pheromones; Photochemical Processes; Photons; Photosystem II Protein Complex; Plant Development; Plant Leaves; Plant Roots; Plant Shoots; Plants; Species Specificity; Stress, Physiological; Water | 2011 |
Benzoxazolin-2(3H)-one (BOA) induced changes in leaf water relations, photosynthesis and carbon isotope discrimination in Lactuca sativa.
Topics: Benzoxazoles; Carbon Isotopes; Chlorophyll; Dose-Response Relationship, Drug; Fluorescence; Lactuca; Nitrogen Isotopes; Pheromones; Photosynthesis; Photosystem II Protein Complex; Plant Leaves; Plant Proteins; Plant Roots; Plant Shoots; Seedlings; Water | 2011 |
A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase.
Topics: Benzoxazoles; Biomimetic Materials; Catalytic Domain; Crystallography, X-Ray; Diphosphates; Enzyme Inhibitors; Humans; Models, Molecular; N-Acetylglucosaminyltransferases | 2011 |
Xenobiotic- and jasmonic acid-inducible signal transduction pathways have become interdependent at the Arabidopsis CYP81D11 promoter.
Topics: Amino Acid Motifs; Arabidopsis; Arabidopsis Proteins; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Benzoxazoles; Cyclopentanes; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Plant; Nucleotidyltransferases; Oxylipins; Plasmids; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Signal Transduction; Transcriptional Activation; Transformation, Genetic; Triiodobenzoic Acids; Xenobiotics | 2012 |
BOA detoxification of four summer weeds during germination and seedling growth.
Topics: Benzoxazines; Benzoxazoles; Germination; Inactivation, Metabolic; Magnoliopsida; Pest Control, Biological; Plant Roots; Plant Shoots; Plant Weeds; Secale; Seedlings | 2012 |
Design, synthesis and structure-activity relationships of novel benzoxazolone derivatives as 18 kDa translocator protein (TSPO) ligands.
Topics: Animals; Benzoxazoles; Carrier Proteins; Dose-Response Relationship, Drug; Drug Design; Ligands; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Structure-Activity Relationship | 2012 |
Phytotoxic effect of 2-benzoxazolinone (BOA) against some vegetable crops.
Topics: Benzoxazoles; Brassicaceae; Dose-Response Relationship, Drug; Herbicides; Pisum sativum; Plant Roots; Seedlings; Vegetables | 2012 |
Evaluation of selective human MAO inhibitory activities of some novel pyrazoline derivatives.
Topics: Benzoxazoles; Chalcone; Humans; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity; Tritium | 2013 |
The synthesis and SAR of calcitonin gene-related peptide (CGRP) receptor antagonists derived from tyrosine surrogates. Part 2.
Topics: Administration, Intranasal; Amino Acids; Animals; Benzoxazoles; Biological Availability; Calcitonin Gene-Related Peptide Receptor Antagonists; Half-Life; Indazoles; Protein Binding; Quinazolinones; Rabbits; Receptors, Calcitonin Gene-Related Peptide; Structure-Activity Relationship; Tyrosine | 2013 |
Synthesis and biological activity of 4-substituted benzoxazolone derivatives as a new class of sEH inhibitors with high anti-inflammatory activity in vivo.
Topics: Animals; Anti-Inflammatory Agents; Benzoxazoles; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Mice; Structure-Activity Relationship | 2013 |
Identification of a novel benzoxazolone derivative as a selective, orally active 18 kDa translocator protein (TSPO) ligand.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Area Under Curve; Avoidance Learning; Benzoxazoles; Carrier Proteins; Cell Line, Tumor; Conflict, Psychological; Humans; Ligands; Male; Mice; Molecular Structure; Motor Activity; Protein Binding; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, GABA-A; Structure-Activity Relationship | 2013 |
Synthesis of 3-alkylbenzoxazolones from N-alkyl-N-arylhydroxylamines by contiguous O-trichloroacetylation, trichloroacetoxy ortho-shift, and cyclization sequence.
Topics: Acetylation; Benzoxazoles; Cyclization; Hydroxylamines; Molecular Structure | 2013 |
Structure-activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT(7) and 5-HT(1A) receptor ligands.
Topics: Benzothiazoles; Benzoxazoles; Ligands; Models, Molecular; Protein Binding; Protein Conformation; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Structure-Activity Relationship | 2014 |
Synthesis and evaluation of new (18)F-labelled acetamidobenzoxazolone-based radioligands for imaging of the translocator protein (18 kDa, TSPO) in the brain.
Topics: Animals; Benzoxazoles; Brain; Brain Ischemia; Carrier Proteins; Fluorine Radioisotopes; Male; Mice; Models, Molecular; Positron-Emission Tomography; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2014 |
Benzoxazolone carboxamides: potent and systemically active inhibitors of intracellular acid ceramidase.
Topics: Amides; Benzoxazoles; Ceramidases; Enzyme Inhibitors | 2015 |
Abutilon theophrasti's defense against the allelochemical benzoxazolin-2(3H)-one: support by Actinomucor elegans.
Topics: Benzoxazoles; Malvaceae; Molecular Sequence Data; Mucorales; Pheromones; Plant Roots; Sequence Analysis, DNA | 2014 |
Synthesis and pharmacological evaluation of benzannulated derivatives as potent and selective sigma-1 protein ligands.
Topics: Benzimidazoles; Benzothiazoles; Benzoxazoles; Cell Line, Tumor; Dose-Response Relationship, Drug; Heterocyclic Compounds; Humans; Hydrocarbons, Brominated; Ligands; Molecular Structure; Receptors, sigma; Structure-Activity Relationship | 2015 |
Benzoxazolin-2(3H)-one inhibits soybean growth and alters the monomeric composition of lignin.
Topics: Benzoxazoles; Biomass; Glycine max; Lignin; Plant Leaves; Plant Roots; Plant Stems | 2015 |
Design, synthesis and biological evaluation of bivalent benzoxazolone and benzothiazolone ligands as potential anti-inflammatory/analgesic agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Benzoxazoles; Carrageenan; Cell Line, Tumor; Chlorocebus aethiops; Dimerization; Drug Design; Edema; Epithelial Cells; Hindlimb; Humans; Kidney; Macrophages; Mice; Molecular Docking Simulation; NF-kappa B; Nitric Oxide Synthase Type II; Rats; Structure-Activity Relationship; Swine; Vero Cells | 2015 |
Catalytic Oxidative Carbonylation of Amino Moieties to Ureas, Oxamides, 2-Oxazolidinones, and Benzoxazolones.
Topics: Amines; Amino Alcohols; Aminophenols; Benzoxazoles; Catalysis; Imidazoles; Ionic Liquids; Oxamic Acid; Oxazolidinones; Oxidation-Reduction; Palladium; Urea | 2015 |
Occurrence of Fusarium verticillioides and Fusarium musae on banana fruits marketed in Hungary.
Topics: Base Sequence; Benzoxazoles; Fruit; Fumonisins; Fungal Proteins; Fusarium; Hungary; Microsatellite Repeats; Molecular Sequence Data; Musa; Mycotoxins; Phylogeny; Sequence Analysis, DNA | 2015 |
Homologues of xenobiotic metabolizing N-acetyltransferases in plant-associated fungi: Novel functions for an old enzyme family.
Topics: Acetyltransferases; Aspergillus; Benzoxazoles; Edible Grain; Fungal Proteins; Fusarium; Xenobiotics | 2015 |
A γ-lactamase from cereal infecting Fusarium spp. catalyses the first step in the degradation of the benzoxazolinone class of phytoalexins.
Topics: Amidohydrolases; Aminophenols; Benzoxazoles; Catalysis; Edible Grain; Fusarium; Genes, Fungal; Inactivation, Metabolic; Phytoalexins; Sesquiterpenes; Transcriptional Activation | 2015 |
Benzoxazolone Carboxamides as Potent Acid Ceramidase Inhibitors: Synthesis and Structure-Activity Relationship (SAR) Studies.
Topics: Acid Ceramidase; Animals; Benzoxazoles; Brain; Enzyme Inhibitors; Humans; Lung; Male; Mice; Mice, Inbred C57BL; Structure-Activity Relationship | 2015 |
New 2-Benzoxazolinone Derivatives with Cytotoxic Activities from the Roots of Acanthus ilicifolius.
Topics: Acanthaceae; Antineoplastic Agents, Phytogenic; Benzoxazoles; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Plant Roots; Structure-Activity Relationship | 2015 |
Benzoxazolinone detoxification by N-Glucosylation: The multi-compartment-network of Zea mays L.
Topics: Acetophenones; Arabidopsis; Benzoxazoles; Biological Assay; Blotting, Western; Carbamates; Cell Wall; Chromatography, High Pressure Liquid; Cytosol; Diacetyl; Ethacrynic Acid; Fusarium; Glucosides; Glutathione Transferase; Glycosylation; Inactivation, Metabolic; Peroxidases; Plant Proteins; Plant Roots; Plants, Genetically Modified; Seedlings; Zea mays | 2016 |
Enantioseparation of N-derivatized amino acids by micro-liquid chromatography/laser induced fluorescence detection using quinidine-based monolithic columns.
Topics: Amino Acids; Benzoxazoles; Chromatography, Liquid; Fluorescence; Glutamic Acid; Lasers; Methacrylates; Permeability; Quinidine; Reproducibility of Results; Stereoisomerism | 2016 |
Two Horizontally Transferred Xenobiotic Resistance Gene Clusters Associated with Detoxification of Benzoxazolinones by Fusarium Species.
Topics: Benzoxazoles; Fungal Proteins; Fusarium; Multigene Family; Xenobiotics | 2016 |
The Fdb3 transcription factor of the Fusarium Detoxification of Benzoxazolinone gene cluster is required for MBOA but not BOA degradation in Fusarium pseudograminearum.
Topics: Benzoxazoles; Fusarium; Gene Expression Regulation, Fungal; Genes, Fungal; Inactivation, Metabolic; Multigene Family; Plant Diseases; Transcription Factors; Triticum | 2016 |
Determination of benzoxazinoids in wheat and rye beers by HPLC-DAD and UPLC-QTOF MS.
Topics: Beer; Benzoxazines; Benzoxazoles; Chromatography, High Pressure Liquid; Hydroxybenzoates; Mass Spectrometry; Plant Extracts; Secale; Triticum | 2016 |
Combretastatin A-4 analogues with benzoxazolone scaffold: Synthesis, structure and biological activity.
Topics: Antineoplastic Agents; Benzoxazoles; Bibenzyls; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Drug Resistance; Humans; Molecular Structure; Small Molecule Libraries | 2016 |
Modified benzoxazolone derivative as 18-kDa TSPO ligand.
Topics: Animals; Benzoxazoles; Ligands; Mice; Molecular Docking Simulation; Protein Binding; Receptors, GABA | 2017 |
The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis.
Topics: Animals; Benzoxazoles; Drug Discovery; Enzyme Inhibitors; HEK293 Cells; Humans; Indazoles; Kynurenine; Kynurenine 3-Monooxygenase; Pancreatitis; Rats; Tryptophan | 2017 |
Expression and characterization of the key enzymes involved in 2-benzoxazolinone degradation by Pigmentiphaga sp. DL-8.
Topics: Alcaligenaceae; Amino Acid Sequence; Aminophenols; Benzoxazoles; Cloning, Molecular; Enzyme Stability; Hydrogen-Ion Concentration; Recombinant Proteins; Substrate Specificity; Temperature | 2018 |
Interspecies-cooperations of abutilon theophrasti with root colonizing microorganisms disarm BOA-OH allelochemicals.
Topics: Benzoxazoles; Catalase; Chromatography, High Pressure Liquid; Glucosides; Hydrogen Peroxide; Hydroxylation; Isomerism; Malvaceae; Pheromones; Plant Extracts; Plant Roots; Plant Shoots; Seedlings; Species Specificity | 2017 |
Identification of novel 2-benzoxazolinone derivatives with specific inhibitory activity against the HIV-1 nucleocapsid protein.
Topics: Anti-HIV Agents; Benzoxazoles; Dose-Response Relationship, Drug; HIV; Microbial Sensitivity Tests; Molecular Structure; Nucleocapsid Proteins; Structure-Activity Relationship | 2018 |
Anti-inflammatory effects of 4-o-methyl-benzenesulfonyl benzoxazolone (MBB) in vivo and in vitro as a novel NSAIDs lead compound.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzoxazoles; Cyclooxygenase 1; Cyclooxygenase 2; Edema; Female; Inflammation; Interleukin-1beta; Interleukin-6; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; RAW 264.7 Cells; Tumor Necrosis Factor-alpha | 2018 |
Identification of 2-benzoxazolinone derivatives as lead against molecular targets of diabetic complications.
Topics: Aldehyde Reductase; Antioxidants; Benzoxazoles; Binding Sites; Catalytic Domain; Diabetes Complications; Enzyme Inhibitors; Glycation End Products, Advanced; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Structure-Activity Relationship | 2018 |
A QSAR Study for Analgesic and Anti-inflammatory Activities of 5-/6-Acyl-3-alkyl-2-Benzoxazolinone Derivatives.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzoxazoles; Drug Design; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship | 2019 |
Semisynthesis and insecticidal bioactivities of benzoxazole and benzoxazolone derivatives of honokiol, a naturally occurring neolignan derived from Magnolia officinalis.
Topics: Animals; Benzoxazoles; Biphenyl Compounds; Insecticides; Larva; Lignans; Magnolia; Models, Molecular; Molecular Structure; Moths; Plant Bark; Plant Stems | 2020 |
Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors.
Topics: Acid Ceramidase; Administration, Oral; Animals; Benzoxazoles; Brain; Cell Line, Tumor; Enzyme Inhibitors; Female; Gaucher Disease; Humans; Leukodystrophy, Globoid Cell; Male; Mice; Molecular Structure; Psychosine; Structure-Activity Relationship | 2020 |
New halogenated chalcones with cytotoxic and carbonic anhydrase inhibitory properties: 6-(3-Halogenated phenyl-2-propen-1-oyl)-2(3H)-benzoxazolones.
Topics: Antineoplastic Agents; Benzoxazoles; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Cell Line; Cell Proliferation; Chalcones; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Halogenation; Humans; Molecular Structure; Structure-Activity Relationship | 2020 |
Polyhalonitrobutadienes as Versatile Building Blocks for the Biotargeted Synthesis of Substituted N-Heterocyclic Compounds.
Topics: Anti-Bacterial Agents; Benzimidazoles; Benzoquinones; Benzoxazoles; Butadienes; Cell Survival; Heterocyclic Compounds; Imidazolidines; Inhibitory Concentration 50; Pyrazoles; Pyrimidines; Staphylococcus aureus; Thiophenes | 2020 |
Synthesis and Apoptotic Activities of New 2(3H)-benzoxazolone Derivatives in Breast Cancer Cells.
Topics: Analgesics; Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Benzoxazoles; Breast Neoplasms; Caspase 3; Drug Screening Assays, Antitumor; Electron Transport Complex IV; Fas Ligand Protein; Humans; MCF-7 Cells; Piperazine; Structure-Activity Relationship | 2021 |
Docking Studies and Antiproliferative Activities of 6-(3-aryl-2-propenoyl)-2(3H)- benzoxazolone Derivatives as Novel Inhibitors of Phosphatidylinositol 3-Kinase (PI3Kα).
Topics: Antineoplastic Agents; Apoptosis; Benzoxazoles; Caspase 3; Cell Line, Tumor; Cell Proliferation; Chalcone; Drug Design; Humans; L-Lactate Dehydrogenase; Molecular Docking Simulation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Binding; Structure-Activity Relationship | 2021 |
4-Sulfonyloxy/alkoxy benzoxazolone derivatives with high anti-inflammatory activities: Synthesis, biological evaluation, and mechanims of action via p38/ERK-NF-κB/iNOS pathway.
Topics: Animals; Anti-Inflammatory Agents; Benzoxazoles; Binding Sites; Down-Regulation; Edema; Extracellular Signal-Regulated MAP Kinases; Lipopolysaccharides; Macrophages; Mice; Molecular Docking Simulation; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; RAW 264.7 Cells; Signal Transduction; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2021 |
Design and synthesis of new disubstituted benzoxazolone derivatives that act as iNOS inhibitors with potent anti-inflammatory activity against LPS-induced acute lung injury (ALI).
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Benzoxazoles; Disease Models, Animal; Drug Design; Edema; Gene Expression Regulation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Lung; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; RAW 264.7 Cells | 2020 |
Design, synthesis and biological evaluation of new benzoxazolone/benzothiazolone derivatives as multi-target agents against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Benzoxazoles; Butyrylcholinesterase; Cell Proliferation; Cells, Cultured; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Horses; Humans; Mice; Molecular Structure; Neuroprotective Agents; Protein Aggregates; Structure-Activity Relationship; Thiazoles | 2021 |
Multifunctional agents based on benzoxazolone as promising therapeutic drugs for diabetic nephropathy.
Topics: Aldehyde Reductase; Animals; Antioxidants; Benzoxazoles; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; HEK293 Cells; Humans; Hypoglycemic Agents; Mice; Molecular Docking Simulation; Molecular Structure; Protein Binding; Structure-Activity Relationship | 2021 |
Deconstruction - Reconstruction: Analysis of the Crucial Structural Elements of GluN2B-Selective, Negative Allosteric NMDA Receptor Modulators with 3-Benzazepine Scaffold.
Topics: Adrenergic alpha-Antagonists; Allosteric Regulation; Animals; Benzazepines; Benzoxazoles; Binding Sites; Excitatory Amino Acid Antagonists; Humans; Kinetics; Molecular Docking Simulation; Oocytes; Patch-Clamp Techniques; Piperidines; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Structure-Activity Relationship; Tritium; Xenopus laevis | 2021 |
In silico guided design of non-covalent inhibitors of DprE1: synthesis and biological evaluation.
Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Benzoxazoles; Computer Simulation; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Quantitative Structure-Activity Relationship | 2021 |
Tolerance of 2-Benzoxazolinone and Interactions with Grass and Pine Hosts in a Population of
Topics: Benzoxazoles; Fusarium; Pinus; Plant Diseases; Poaceae | 2021 |
Negative allosteric modulators of NMDA receptors with GluN2B subunit: Alanine-derived benzoxazolone bioisosteres of 2-methyl-3-benzazepine-1,7-diols.
Topics: Alanine; Benzazepines; Benzoxazoles; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2022 |
Phenol-Benzoxazolone bioisosteres: Synthesis and biological evaluation of tricyclic GluN2B-selective N-methyl- d-aspartate receptor antagonists.
Topics: Benzazepines; Benzoxazoles; Ketones; Phenol; Phenols; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2022 |