benzothiazole has been researched along with thiazoles in 128 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (14.06) | 18.7374 |
| 1990's | 30 (23.44) | 18.2507 |
| 2000's | 67 (52.34) | 29.6817 |
| 2010's | 11 (8.59) | 24.3611 |
| 2020's | 2 (1.56) | 2.80 |
| Authors | Studies |
|---|---|
| Greco, MN; Hageman, WE; Persico, FJ; Powell, ET; Tighe, JJ | 1 |
| Jakubik, T; Lesko, J; Michalkova, A | 1 |
| Burridge, MJ; Lusby, WR; Norval, RA; Sonenshine, DE; Yunker, CE | 1 |
| Chissick, H; Fowler, AM; Frearson, FJ; Gittins, M; Swinbourne, FJ; Wilson, K | 1 |
| Preussmann, R; Spiegelhalder, B; Wacker, CD | 1 |
| Hayes, LS; Lloyd, DB; Thompson, JF | 1 |
| Sänger, I; Schütze, HR; Striebel, HP; Zahner, H | 1 |
| Becker, RS; Lenoble, C | 1 |
| Lipkowitz, KB; McCracken, RO | 1 |
| Airaudo, CB; Gayte-Sorbier, A; Laurent, P; Momburg, R | 1 |
| Franz, M; Mehlhorn, H; Striebel, HP; Zahner, H | 1 |
| Caujolle, R; Gayral, P; Loiseau, P; Payard, M | 1 |
| Davies, KP; Köhler, P; Zahner, H | 1 |
| Fomina, EI; Ivanov, SD; Kvitko, IIa; Nagorskaia, LP; Rtishchev, NI | 1 |
| Hajos, ZG; Press, JB; Sanfilippo, PJ; Scott, CK; Shriver, DA; Urbanski, M | 1 |
| Kovárová, A; Krácmar, J; Krácmarová, J; Remsová, M | 1 |
| Müller, HA; Sänger, I; Schultheiss, K; Schütze, HR; Striebel, HP; Zahner, H | 1 |
| Arima, H; Mase, T; Murase, K; Tomioka, K; Yamada, T | 1 |
| Farrell, GC; Lacey, E; Murray, M | 1 |
| Białasiewicz, D; Domagalina, E; Kurnatowska, A | 1 |
| Holbová, E; Wildt, S | 1 |
| Airaudo, CB; Assaf, A; Gayte-Sorbier, A; Salmona, G | 1 |
| Hemminki, K; Korhonen, A; Vainio, H | 1 |
| De Vos, D; De Wever, H; Verachtert, H | 1 |
| De Wever, H; Verachtert, H | 1 |
| Amico-Roxas, M; Caruso, A; Cutuli, V; Di Pietro, E; Modica, M; Russo, F; Santagati, A; Santagati, M | 1 |
| Boxer, PA; Boyd, DK; Copeland, LF; Hays, SJ; Johnson, G; Ortwine, DF; Rice, MJ; Schwarz, RD; Vartanian, MG | 1 |
| Navaratnam, V | 1 |
| Cetinkaya, E; Durmaz, R; Küçükbay, H | 1 |
| Foltinova, P; Halgas, J; Zahradnik, P | 1 |
| Chissick, HH; Fowler, AM; Frearson, MJ; Wilson, K | 1 |
| Bradshaw, TD; Fichtner, I; Lelieveld, P; McCall, CJ; Shi, DF; Stevens, MF; Wrigley, S | 1 |
| Auriola, S; Liesivuori, J; Manninen, A; Pasanen, M; Turunen, T; Vartiainen, M | 1 |
| Cho, MK; Kim, SG | 1 |
| Nebot-Gil, I; Sánchez-Marín, J; Torrens, F | 1 |
| Durmaz, B; Küçükbay, H | 1 |
| el-Shaaer, HM; Gasparová, R; Lácová, M; Odlerová, Z | 1 |
| Doğruer, DS; Sahin, MF; Unlü, S; Yeşilada, E | 1 |
| Higaki, T; Kato, H; Kishida, F; Nakamura, Y; Nakatsuka, I | 1 |
| Bradshaw, TD; Fiebig, HH; Garner, C; Kelland, L; Paull, KD; Schultz, RJ; Shi, DF; Stevens, MF; Wilson, A; Wrigley, S | 1 |
| De Wever, H; Stolz, A; Verachtert, H; Vereecken, K | 1 |
| Heitsch, H; Schölkens, BA; Wagner, A; Wirth, K | 1 |
| Bellavia, V; Fanelli, R; Natangelo, M; Rotilio, D | 1 |
| Ai, J; Fomum, ZT; Nielsen, M; Sterner, O; Wahe, H; Wang, X; Witt, MR | 1 |
| Jaycox, LB; Olsen, LD | 1 |
| Brinkman, UA; Louter, AJ; Ramalho, S; Slobodník, J; van Baar, BL | 1 |
| Andreozzi, R; D'Apuzzo, A; Marotta, R | 1 |
| Asakura, S; Hakura, A; Kobayashi, N; Sato, G; Tsukidate, K; Tsutsui-Hiyoshi, Y | 1 |
| Besse, P; Boyse, G; Combourieu, B; De Wever, H; Delort, AM; Sancelme, M | 1 |
| Bradshaw, TD; Chua, MS; Shi, DF; Stevens, MF; Westwell, AD | 1 |
| Ishikawa, M; Kobayashi, K; Naya, A; Noguchi, K; Ohtake, N; Ohwaki, K; Saeki, T | 1 |
| Aoki, H; Deguchi, M; Iwata, S; Kumagai, T; Tanaka, K | 1 |
| Caignard, DH; Chavatte, P; Espiard, JG; Lesieur, D; Poupaert, JH; Yous, S | 1 |
| Besse, P; De Wever, H; Verachtert, H | 1 |
| Donovalová, J; Gáplovský, A; Magdolen, P; Toma, S; Zahradník, P | 1 |
| Brattsten, LB; Suwanchaichinda, C | 1 |
| Fujiwara, K; Kumata, H; Masuda, K; Sakural, T; Sato, Y; Takada, H; Yamada, J | 1 |
| Jekel, M; Kloepfer, A; Reemtsma, T; Stueber, M; Zywicki, B | 1 |
| David, WM; Kerwin, SM; Kumar, D; Salazar, M; Tuntiwechapikul, W | 1 |
| Tale, RH | 1 |
| Di Donato, P; Napolitano, A; Prota, G | 1 |
| Avila-Ríos, S; Gómez-Puyou, A; López-Calahorra, F; Pérez-Montfort, R; Rodríguez-Romero, A; Téllez-Valencia, A; Tuena de Gómez-Puyou, M | 1 |
| Barnickel, G; Boeddrich, A; Böttcher, H; Bröcker, W; Dunkel, I; Engemann, S; Heiser, V; Herhaus, C; Lehrach, H; Lurz, R; Nordhoff, E; Rautenberg, S; Schugardt, N; Waelter, S; Wanker, EE | 1 |
| Bahekar, RH; Bhusari, KP; Chopade, RS; Khedekar, PB; Rao, AR | 1 |
| Demopoulos, VJ; Nicolaou, I; Zaher, N | 1 |
| Baumberg, S; Besse, P; Combourieu, B; Delort, AM; Diab, A; Haroune, N; Kloepfer, A; Knapp, JS; Reemtsma, T; Sancelme, M | 1 |
| Alzuet, G; Borrás, J; Castillo Agudo, L; García-Granda, S; González-Alvarez, M; Montejo-Bernardo, JM | 1 |
| Kim, K; Kim, YH; Kwon, JH; Kwon, JW | 1 |
| Barnes, KA; Castle, L; Damant, AP; Read, WA; Speck, DR | 1 |
| Paramashivappa, R; Phani Kumar, P; Srinivasa Rao, A; Subba Rao, PV | 1 |
| Achuo, AE; Audenaert, K; Höfte, M; Meziane, H | 1 |
| Gallagher, WP; Maleczka, RE | 1 |
| Brzezińska, E; Kośka, G; Walczyński, K | 1 |
| Brzezińsk, E; Kośka, G; Kłimczak, A | 1 |
| Bradshaw, TD; Browne, HL; Laughton, CA; O'Brien, SE; Stevens, MF; Westwell, AD | 1 |
| Fujita, S; Inoue, J; Nakajima, E; Sakai, Y; Sakamoto-Mizutani, K; Shirasaki, Y; Takayama, W | 1 |
| Allam, SR; El-Nassry, SM; El-Zawawy, LA; Mahran, MA | 1 |
| GRUNBERG, E; TITSWORTH, E | 1 |
| SASAKI, M | 2 |
| SASAKI, M; YAMORI, T | 1 |
| HO, WH; LO, RS; LU, CJ; SHI, CM; YU, LK | 1 |
| Chohan, ZH; Scozzafava, A; Supuran, CT | 1 |
| Azizian, MF; Nelson, PO; Thayumanavan, P; Williamson, KJ | 1 |
| García-Báez E, EV; Höpfl, H; Martínez-Martínez, FJ; Padilla-Martínez, II | 1 |
| Busonera, B; Cabras, CA; Geronikaki, A; Incerti, M; La Colla, P; Poni, G; Vicini, P | 1 |
| Covell, DG; Monks, A; Rabow, AA; Shoemaker, RH; Thanki, N; Wallqvist, A | 1 |
| Al-Masoudi, NA; Gesson, JP; Khodair, AI | 1 |
| Bonham, L; Gong, B; Hong, F; Klein, P; Kohm, C | 1 |
| Caleta, I; Cetina, M; Grdisa, M; Karminski-Zamola, G; Mrvos-Sermek, D; Pavelić, K; Tralić-Kulenović, V | 1 |
| Gu, Y; Hu, J; Hu, L; Li, W; Luo, M; Niu, F; Wu, Q; Ye, Y | 1 |
| Avellaneda, A; De Clercq, E; Delmas, F; Di Giorgio, C; Galy, JP; Robin, M; Timon-David, P | 1 |
| Imahori, T | 1 |
| Debnath, ML; Holt, DP; Huang, GF; Klunk, WE; Mathis, CA; Shao, L; Wang, Y | 1 |
| Cho, H; Chung, Y; Lee, S; Shin, YK; Zhan, CG | 1 |
| Gnirss, R; Jekel, M; Kloepfer, A; Reemtsma, T | 1 |
| Azas, N; Darque, A; Di Giorgio, C; Galy, J; Gasquet, M; Hout, S; Robin, M; Timon-David, P | 1 |
| Ebara, S; Kaneko, Y; Nakazawa, K; Suwa, K; Yamazaki, K; Yasuno, K | 1 |
| Hsu, T; Huang, WH; Jiaang, WT; Lee, SJ; Mahindroo, N; Tseng, HY; Wang, SF; Wu, SH; Yang, YN | 1 |
| Carone, D; Franco, M; Latrofa, A; Lopedota, A; Rosato, A; Vitali, C | 1 |
| Tran, K; Young, D; Zeng, EY | 1 |
| Agatsuma, T; Furukawa, H; Hayakawa, I; Hayashi, N; Iwasaki, S; Koyama, K; Kurakata, S; Oda, Y; Sugano, Y; Tanzawa, F; Yoshida, M | 1 |
| LeVine, H | 1 |
| Barker, AL; Bates, GP; Beunard, JL; Hockly, E; Holt, K; Lowden, PA; Moffitt, H; Moolman, DL; Revington, AP; Sathasivam, K; Sunshine, S; Tse, J; Wanker, EE; Woodman, B | 1 |
| Costantino, L; Hennig, B; Matuszczak, B; Nagano, M; Rakowitz, D; Steger, S | 1 |
| Naderi, S; Rahmati, A; Shaabani, A | 1 |
| Choi, SJ; Choo, HY; Han, G; Kim, SW; Lee, SK; Park, HJ | 1 |
| Ganeshapillai, D; Potter, BV; Purohit, A; Reed, MJ; Smith, A; Su, X; Vicker, N | 1 |
| Matysiak, J | 1 |
| Gao, X; Hu, D; Jin, L; Song, B; Xu, R; Yang, S; Zhang, G; Zhang, S | 1 |
| Costas, M; Gómez Puyou, A; López-Calahorra, F; Olivares-Illana, V; Pérez-Montfort, R; Rodríguez-Romero, A; Tuena de Gómez-Puyou, M | 1 |
| Kishimoto, N; Ohno, K; Yamazaki, M | 1 |
| Borghgraef, P; Bormans, G; Cleynhens, J; Kung, H; Serdons, K; Van Leuven, F; Vanderghinste, D; Verbruggen, A; Verduyckt, T | 1 |
| Hu, C; Lee, H; Solomon, VR | 1 |
| Brown, C; Capule, CC; Dewhurst, S; Doran, TM; Feng, C; Nilsson, BL; Olsen, JS; Rubinshtein, M; Srivastava, RK; Yang, J | 1 |
| MERCURY, ML; SHERRILL, ML; VINCENT, SM | 1 |
| Cisek, K; Honson, NS; Jensen, JR; Kuret, J | 1 |
| Dung, PT; Han, BW; Han, SB; Hong, JT; Hue, VT; Kim, Y; Nam, NH; Oanh, DT; Park, SH; Tung, TT | 1 |
| Cai, J; Chen, J; Ji, M; Sun, M; Wang, P; Wu, X; Zong, X | 1 |
| Bergfors, A; Gillberg, PG; Marutle, A; Ni, R; Nordberg, A | 1 |
| Huang, C; Liu, H; Liu, L; Peng, J; Shao, Y; Zhang, L | 1 |
| Li, H; Li, X; Tang, C; Wang, C; Wang, J; Wei, X; Zhang, C | 1 |
| Ciftci, GA; Demir, B; Levent, S; Saglik, BN; Temel, HE; Yurttas, L | 1 |
| Abbasova, M; Alwasel, SH; Beydemir, Ş; Farzaliyev, V; Gulçin, İ; Huyut, Z; Safarova, L; Sujayev, A; Supuran, CT; Taslimi, P | 1 |
| Ding, Q; Ge, J; Jiang, Z; Liu, D; Luo, P; Peng, Y | 1 |
| Cheng, X; Liu, D; Wang, Y | 1 |
| Daidone, G; Maggio, B; Plescia, F; Raffa, D | 1 |
| Ajiro, M; Alqasem, AA; Clark, B; Hagiwara, M; Iida, K; Ladomery, MR; Li, L; Oltean, S; Perks, CM; Porazinski, SR; Uzor, S; Wilson, ID | 1 |
5 review(s) available for benzothiazole and thiazoles
| Article | Year |
|---|---|
Recent advances in the chemotherapy of lymphatic filariasis.
Topics: Benzimidazoles; Benzothiazoles; Diethylcarbamazine; Elephantiasis, Filarial; Filaricides; Humans; Ivermectin; Thiabendazole; Thiazoles | 1993 |
Microbial transformations of 2-substituted benzothiazoles.
Topics: Bacteria; Benzothiazoles; Biodegradation, Environmental; Biotechnology; Biotransformation; Environmental Microbiology; Environmental Pollutants; Industrial Waste; Pilot Projects; Sewage; Thiazoles | 2001 |
Mining the NCI screening database: explorations of agents involved in cell cycle regulation.
Topics: Animals; Antineoplastic Agents; Benzothiazoles; Cell Cycle Proteins; Cytochrome P-450 CYP1A1; Databases as Topic; Drug Screening Assays, Antitumor; Humans; National Institutes of Health (U.S.); Neoplasms; Thiazoles; United States | 2003 |
[A novel deprotonative functionalization of aromatics with phosphazene base].
Topics: Benzothiazoles; Chemistry, Organic; Hydrocarbons, Aromatic; Iodides; Organic Chemistry Phenomena; Organophosphorus Compounds; Protons; Pyridazines; Pyrimidines; Thiadiazoles; Thiazoles; Zinc Compounds | 2004 |
4-(3H)-quinazolinones N-3 substituted with a five membered heterocycle: A promising scaffold towards bioactive molecules.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Anticonvulsants; Antineoplastic Agents; Antioxidants; Antitubercular Agents; Benzothiazoles; Bronchodilator Agents; Humans; Molecular Structure; Nitrogen; Oxygen; Quinazolinones; Sulfur; Thiazoles | 2021 |
123 other study(ies) available for benzothiazole and thiazoles
| Article | Year |
|---|---|
Benzothiazole hydroxy ureas as inhibitors of 5-lipoxygenase: use of the hydroxyurea moiety as a replacement for hydroxamic acid.
Topics: Animals; Benzothiazoles; Calcimycin; Dogs; Humans; Hydroxamic Acids; Hydroxyurea; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Methemoglobin; Mice; Molecular Structure; Peritonitis; SRS-A; Structure-Activity Relationship; Thiazoles | 1992 |
Gas chromatographic-mass spectrometric detection of trace amounts of organic compounds in the intravenous solution Infusio Darrowi.
Topics: Benzothiazoles; Dibutyl Phthalate; Drug Contamination; Gas Chromatography-Mass Spectrometry; Glucose; Infusions, Intravenous; Lactates; Phenols; Potassium Chloride; Sodium Chloride; Sodium Lactate; Solutions; Thiazoles | 1992 |
Comparison of known and suspected pheromonal constituents in males of African ticks, Amblyomma hebraeum Koch and Amblyomma variegatum (Fabricius).
Topics: Animals; Arachnid Vectors; Benzaldehydes; Benzothiazoles; Benzyl Alcohol; Benzyl Alcohols; Chlorophenols; Chromatography, Gas; Fatty Acids; Feeding Behavior; Female; Gas Chromatography-Mass Spectrometry; Heartwater Disease; Male; Nitrophenols; Salicylates; Sex Attractants; Sexual Behavior, Animal; Thiazoles; Tick Infestations; Ticks | 1991 |
Metabolism of benzothiazole. I. Identification of ring-cleavage products.
Topics: Animals; Benzothiazoles; Chromatography, Gas; Guinea Pigs; Hydrolysis; In Vitro Techniques; Male; Mass Spectrometry; Sulfatases; Thiazoles | 1991 |
New sulfenamide accelerators derived from 'safe' amines for the rubber and tyre industry.
Topics: Benzothiazoles; Humans; Industry; Nitrosamines; Occupational Exposure; Rubber; Thiazoles | 1991 |
Modulation of firefly luciferase stability and impact on studies of gene regulation.
Topics: Alkaline Phosphatase; Animals; Benzothiazoles; Cell Line; Coleoptera; Firefly Luciferin; Gene Expression Regulation; Half-Life; Humans; Indoles; Luciferases; Phenols; Thiazoles; Trypsin | 1991 |
Antifilarial activities of benzazole derivatives. 3. Effects of benzothiazoles on third stage larvae and preadult worms of Acanthocheilonema viteae, Brugia malayi and B. pahangi in Mastomys natalensis.
Topics: Animals; Benzothiazoles; Brugia; Dipetalonema; Dipetalonema Infections; Dose-Response Relationship, Drug; Elephantiasis, Filarial; Larva; Muridae; Thiazoles | 1990 |
New features in the photophysics and photochemistry of 2-(2'-hydroxyphenyl)benzothiazoles introduced by amine substitution.
Topics: Amines; Benzothiazoles; Photochemistry; Photolysis; Spectrophotometry; Thiazoles | 1990 |
Structure-activity relationships of benzothiazole and benzimidazole anthelmintics: a molecular modeling approach to in vivo drug efficacy.
Topics: Animals; Anthelmintics; Benzimidazoles; Benzothiazoles; Hymenolepiasis; Hymenolepis; Male; Models, Chemical; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiazoles | 1990 |
Leaching of antioxidants and vulcanization accelerators from rubber closures into drug preparations.
Topics: Antioxidants; Benzothiazoles; Drug Contamination; Drug Packaging; Rubber; Syringes; Thiazoles | 1990 |
In vivo effect of benzothiazole and amoscanate derivatives on the fine structure of adult Brugia spp. and Litomosoides carinii.
Topics: Aniline Compounds; Animals; Anthelmintics; Benzothiazoles; Brugia; Diphenylamine; Elephantiasis, Filarial; Female; Filariasis; Filaricides; Filarioidea; Isothiocyanates; Microscopy, Electron; Muridae; Piperazines; Thiazoles; Thiocyanates | 1990 |
[Synthesis of 2-aryl benzothiazoles and research on its antiparasitic activity].
Topics: Animals; Antinematodal Agents; Antiprotozoal Agents; Benzothiazoles; In Vitro Techniques; Male; Nippostrongylus; Rats; Rats, Inbred Strains; Thiazoles | 1989 |
Litomosoides carinii: mode of action in vitro of benzothiazole and amoscanate derivatives with antifilarial activity.
Topics: Anaerobiosis; Aniline Compounds; Animals; Anthelmintics; Benzothiazoles; Diphenylamine; Energy Metabolism; Female; Filaricides; Filarioidea; Hydrogen-Ion Concentration; Isothiocyanates; Movement; Oxygen Consumption; Piperazines; Rotenone; Thiazoles; Thiocyanates; Time Factors | 1989 |
[Spectral features of amines of 2-phenylbenzazoles upon interaction with DNA].
Topics: Amines; Benzimidazoles; Benzothiazoles; Benzoxazoles; Chemical Phenomena; Chemistry; DNA; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thiazoles | 1989 |
Synthesis of (aryloxy)alkylamines. 1. Novel antisecretory agents with H+K+-ATPase inhibitory activity.
Topics: Adenosine Triphosphatases; Amines; Aminopyrine; Animals; Benzothiazoles; Benzoxazoles; Bucladesine; Chemical Phenomena; Chemistry; Cimetidine; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine; Ligation; Male; Omeprazole; Parietal Cells, Gastric; Pyloric Antrum; Ranitidine; Rats; Structure-Activity Relationship; Thiazoles | 1988 |
[UV-spectrophotometry in drug control. 41. Drug substances with chromophores and auxochromes in monocyclic compounds (pyrazolone, pyrazolidine, pyridazine, pyrimidine and pyrazine) and bicyclic compounds (benzoxazole, imidazole, benzthiazole and indene)].
Topics: Benzothiazoles; Benzoxazoles; Imidazoles; Pharmaceutical Preparations; Pyrazines; Pyrazoles; Pyridazines; Pyrimidines; Spectrophotometry, Ultraviolet; Thiazoles | 1988 |
Antifilarial activities of benzazole derivatives. 1. Macrofilaricidal effects against Litomosoides carinii, Dipetalonema viteae, Brugia malayi, and B. pahangi in Mastomys natalensis.
Topics: Administration, Oral; Animals; Anthelmintics; Benzothiazoles; Benzoxazoles; Brugia; Dipetalonema; Dipetalonema Infections; Elephantiasis, Filarial; Female; Filariasis; Filaricides; Filarioidea; Injections, Subcutaneous; Male; Muridae; Thiazoles | 1988 |
Imidazo[2,1-b]benzothiazoles. 2. New immunosuppressive agents.
Topics: Animals; Antibody Formation; Benzothiazoles; Female; Hemolytic Plaque Technique; Hypersensitivity, Delayed; Imidazoles; Immunity, Cellular; Immunosuppressive Agents; Male; Mice; Mice, Inbred ICR; Structure-Activity Relationship; Thiazoles | 1986 |
New heterocyclic modifiers of oxidative drug metabolism--I. 6-Substituted-2-aminobenzothiazoles.
Topics: Aminopyrine N-Demethylase; Animals; Benzothiazoles; Binding, Competitive; Cytochrome P-450 Enzyme System; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Rats; Rats, Inbred Strains; Solubility; Structure-Activity Relationship; Thiazoles | 1986 |
[Preliminary evaluation of the trichomonacidal effect of new derivatives of benzoisoxazolinone, benzoxazolinone and benzothiazolinone].
Topics: Animals; Antitrichomonal Agents; Benzothiazoles; Benzoxazoles; Drug Evaluation, Preclinical; Thiazoles; Trichomonas | 1985 |
[Mannich's compounds on the basis of benzothiazole as a potential anorectic].
Topics: Animals; Appetite Depressants; Benzothiazoles; Eating; Female; Motor Activity; Rats; Thiazoles | 1984 |
Mass spectral identification of benzothiazole derivatives leached into injections by disposable syringes.
Topics: Benzothiazoles; Disposable Equipment; Mass Spectrometry; Syringes; Thiazoles | 1984 |
Embryotoxicity of benzothiazoles, benzenesulfohydrazide, and dithiodimorpholine to the chicken embryo.
Topics: Abnormalities, Drug-Induced; Animals; Benzenesulfonates; Benzothiazoles; Chick Embryo; Dose-Response Relationship, Drug; Eye Abnormalities; Lethal Dose 50; Morpholines; Poultry Diseases; Rubber; Thiazoles | 1982 |
Parameters affecting the degradation of benzothiazoles and benzimidazoles in activated sludge systems.
Topics: Benzimidazoles; Benzothiazoles; Biodegradation, Environmental; Biotechnology; Chemical Industry; Oxygen Consumption; Rubber; Thiazoles; Waste Disposal, Fluid | 1993 |
2-Mercaptobenzothiazole degradation in laboratory fed-batch systems.
Topics: Bacteria; Benzothiazoles; Biodegradation, Environmental; Biotechnology; Chemical Industry; Industrial Waste; Rubber; Thiazoles | 1994 |
Synthesis and pharmacological properties of benzothiazole, 1,3-4-oxadiazole and 1,3,4-thiadiazole derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Benzothiazoles; Carrageenan; Edema; Lethal Dose 50; Male; Mice; Oxadiazoles; Pain Measurement; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Thiadiazoles; Thiazoles | 1994 |
Substituted 2-benzothiazolamines as sodium flux inhibitors: quantitative structure-activity relationships and anticonvulsant activity.
Topics: Animals; Anticonvulsants; Ataxia; Benzothiazoles; Electroshock; Male; Mice; Rats; Rats, Inbred Strains; Sodium; Sodium Channels; Structure-Activity Relationship; Thiazoles | 1994 |
Synthesis and antimicrobial activity of substituted benzimidazole, benzothiazole and imidazole derivatives.
Topics: Anti-Bacterial Agents; Bacteria; Benzimidazoles; Benzothiazoles; Imidazoles; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Spectrophotometry, Infrared; Thiazoles | 1995 |
Qsar study of the toxicity of benzothiazolium salts against Euglena gracilis: the Free-Wilson approach.
Topics: Animals; Benzothiazoles; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Euglena gracilis; Molecular Structure; Structure-Activity Relationship; Thiazoles | 1996 |
The role of aldehyde oxidase in the in vivo metabolism of benzothiazole.
Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Benzothiazoles; Guinea Pigs; In Vitro Techniques; Kinetics; Thiazoles | 1995 |
Antitumor benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Benzimidazoles; Benzothiazoles; Benzoxazoles; Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Metallothionein 3; Mice; Mice, Nude; Structure-Activity Relationship; Thiazoles; Transplantation, Heterologous | 1996 |
Determination of urinary 2-mercaptobenzothiazole (2-MBT), the main metabolite of 2-(thiocyanomethylthio)benzothiazole (TCMTB) in humans and rats.
Topics: Animals; Benzothiazoles; Gas Chromatography-Mass Spectrometry; Humans; Intubation, Gastrointestinal; Male; Microsomes, Liver; Rats; Rats, Wistar; Thiazoles; Thiocyanates | 1996 |
Expression of glutathione S-transferases Ya, Yb1, Yb2, Yc1 and Yc2 and microsomal epoxide hydrolase genes by thiazole, benzothiazole and benzothiadiazole.
Topics: Animals; Benzothiazoles; Cytosol; Dose-Response Relationship, Drug; Epoxide Hydrolases; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Liver; Microsomes, Liver; Rats; RNA, Messenger; Thiadiazoles; Thiazoles; Time Factors | 1996 |
Torsional effects on the molecular polarizabilities of the benzothiazole (A)-benzobisthiazole (B) oligomer A-B13-A.
Topics: Benzothiazoles; Computer Graphics; Computer Simulation; Models, Chemical; Molecular Conformation; Polymers; Solubility; Static Electricity; Thiazoles | 1996 |
Antifungal activity of organic and organometallic derivatives of benzimidazole and benzothiazole.
Topics: Antifungal Agents; Benzimidazoles; Benzothiazoles; Candida albicans; Microbial Sensitivity Tests; Organometallic Compounds; Thiazoles | 1997 |
Synthesis and antimycobacterial activity of some new 3-heterocyclic substituted chromones.
Topics: Antitubercular Agents; Benzimidazoles; Benzothiazoles; Chromones; Heterocyclic Compounds; Mycobacterium; Mycobacterium tuberculosis; Thiazoles | 1997 |
Anti-nociceptive and anti-inflammatory activity of some (2-benzoxazolone-3-yl and 2-benzothiazolone-3-yl)acetic acid derivatives.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Benzoxazoles; Female; Male; Mice; Structure-Activity Relationship; Thiazoles | 1998 |
Comparison of sex differences in guinea-pig maximization test for detection of skin-sensitizing potential using OECD recommended positive control sensitizers.
Topics: Acrolein; Animals; Benzocaine; Benzothiazoles; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Female; Guinea Pigs; Irritants; Langerhans Cells; Male; Sex Factors; Skin; Thiazoles | 1998 |
Influence of 2-(4-aminophenyl)benzothiazoles on growth of human ovarian carcinoma cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Benzothiazoles; Cell Division; Dose-Response Relationship, Drug; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured | 1998 |
Initial transformations in the biodegradation of benzothiazoles by Rhodococcus isolates.
Topics: Aerobiosis; Anaerobiosis; Benzothiazoles; Biodegradation, Environmental; Culture Media; Rhodococcus; Sewage; Thiazoles | 1998 |
Novel series of O-substituted 8-quinolines and 4-benzothiazoles as potent antagonists of the bradykinin B2 receptors.
Topics: Benzothiazoles; Bradykinin Receptor Antagonists; Quinolines; Receptor, Bradykinin B2; Structure-Activity Relationship; Thiazoles | 1999 |
Analysis of benzothiazole in Italian wines using headspace solid-phase microextraction and gas chromatography-mass spectrometry.
Topics: Benzothiazoles; Drug Residues; Gas Chromatography-Mass Spectrometry; Italy; Microchemistry; Sensitivity and Specificity; Thiazoles; Wine | 2000 |
2-Oxo-2H-Pyrimido[2,1-b]benzothiazoles inhibit brain benzodiazepine receptor binding in vitro.
Topics: Animals; Benzothiazoles; Brain; Flumazenil; GABA Modulators; Humans; Male; Rats; Rats, Wistar; Receptors, GABA-A; Thiazoles | 2000 |
Determination of total sulfur compounds and benzothiazole in asphalt fume samples by gas chromatography with sulfur chemiluminescence detection.
Topics: Air Pollutants, Occupational; Benzothiazoles; Chromatography, Gas; Environmental Monitoring; Humans; Hydrocarbons; Industry; Luminescent Measurements; Occupational Exposure; Sulfur Compounds; Thiazoles | 2000 |
Determination of microcontaminants in sediments by on-line solid-phase extraction-gas chromatography-mass spectrometry.
Topics: Acetates; Benzothiazoles; Chlorofluorocarbons; Environmental Monitoring; Environmental Pollutants; Gas Chromatography-Mass Spectrometry; Geologic Sediments; Hydrocarbons, Aromatic; Methanol; Phenols; Slovakia; Thiazoles; Water Pollutants | 2000 |
A kinetic model for the degradation of benzothiazole by Fe3+-photo-assisted Fenton process in a completely mixed batch reactor.
Topics: Benzothiazoles; Ferric Compounds; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxyl Radical; Models, Theoretical; Osmolar Concentration; Oxidation-Reduction; Thiazoles; Ultraviolet Rays | 2000 |
Assessment of potential mutagenic activities of a novel benzothiazole MAO-A inhibitor E2011 using Salmonella typhimurium YG1029.
Topics: Acetyltransferases; Animals; Benzothiazoles; Biotransformation; Carcinogens; Liver; Liver Neoplasms; Monoamine Oxidase Inhibitors; Mutagenicity Tests; Mutagens; Oxazolidinones; Precancerous Conditions; Rats; Salmonella typhimurium; Structure-Activity Relationship; Thiazoles | 2000 |
Long-range (1)H-(15)N heteronuclear shift correlation at natural abundance: a tool to study benzothiazole biodegradation by two rhodococcus strains.
Topics: Benzothiazoles; Biodegradation, Environmental; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Rhodococcus; Thiazoles | 2001 |
Antitumour benzothiazoles. Part 15: The synthesis and physico-chemical properties of 2-(4-aminophenyl)benzothiazole sulfamate salt derivatives.
Topics: Amines; Antineoplastic Agents; Benzothiazoles; Breast Neoplasms; Drug Stability; Enzyme Activators; Female; Guanylate Cyclase; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Platelet Aggregation Inhibitors; Prodrugs; Solubility; Sulfonic Acids; Thiazoles; Tumor Cells, Cultured | 2001 |
Discovery of a novel CCR3 selective antagonist.
Topics: Acetamides; Benzothiazoles; Chemokine CCL11; Chemokine CCL5; Chemokines, CC; Cytokines; Humans; Receptors, CCR1; Receptors, CCR3; Receptors, Chemokine; Structure-Activity Relationship; Thiazoles | 2001 |
Application of 2-(3,5,6-trifluoro-2-hydroxy-4-methoxyphenyl)benzoxazole and -benzothiazole to fluorescent probes sensing pH and metal cations.
Topics: Benzothiazoles; Benzoxazoles; Biosensing Techniques; Cations; Fluorescent Dyes; Hydrogen-Ion Concentration; Metals; Molecular Probes; Spectrum Analysis; Thiazoles; Zinc | 2001 |
Synthesis and pharmacological evaluation of analgesic 6-substituted 2(3H)-benzothiazolones.
Topics: Analgesics; Animals; Benzothiazoles; Drug Evaluation, Preclinical; Hyperalgesia; Mice; Pain Measurement; Stomach Ulcer; Thiazoles | 2001 |
Spectroscopic study of 2-[2-(4-cyclaminophenyl)ethen-1-yl] benzothiazoles and their N-allylbenzothiazolium bromides. Solvent and substituent effects on their ultraviolet-visible and fluorescence spectra.
Topics: Benzothiazoles; Solvents; Spectrum Analysis; Thiazoles | 2002 |
Induction of microsomal cytochrome P450s by tire-leachate compounds, habitat components of Aedes albopictus mosquito larvae.
Topics: Aedes; Animals; Benzothiazoles; Catalysis; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Habits; Heme; Larva; Microsomes; Organothiophosphates; Pesticide Synergists; Piperonyl Butoxide; Staining and Labeling; Thiazoles | 2002 |
Benzothiazolamines as tire-derived molecular markers: sorptive behavior in street runoff and application to source apportioning.
Topics: Amines; Benzothiazoles; Dust; Environmental Monitoring; Manufactured Materials; Motor Vehicles; Rain; Thiazoles; Water Movements; Water Pollutants, Chemical | 2002 |
Removal of sulfur-organic polar micropollutants in a membrane bioreactor treating industrial wastewater.
Topics: Benzothiazoles; Biodegradation, Environmental; Chromatography, Liquid; Industrial Waste; Mass Spectrometry; Membranes, Artificial; Naphthalenes; Thiazoles; Waste Disposal, Fluid; Water Purification | 2002 |
DNA modification by 4-aza-3-ene-1,6-diynes: DNA cleavage, pH-dependent cytosine-specific interactions, and cancer cell cytotoxicity.
Topics: Alkynes; Antineoplastic Agents; Aza Compounds; Benzimidazoles; Benzothiazoles; Cytosine; DNA Adducts; DNA, Superhelical; Growth Inhibitors; Heterocyclic Compounds, 2-Ring; Hot Temperature; Humans; Hydrogen-Ion Concentration; Hydrolysis; Piperidines; Thiazoles; Tumor Cells, Cultured; U937 Cells | 2002 |
Novel synthesis of 2-arylbenzothiazoles mediated by ceric ammonium nitrate (CAN).
Topics: Antineoplastic Agents; Benzothiazoles; Indicators and Reagents; Nitrates; Oxidants; Oxidation-Reduction; Thiazoles | 2002 |
Metal ions as potential regulatory factors in the biosynthesis of red hair pigments: a new benzothiazole intermediate in the iron or copper assisted oxidation of 5-S-cysteinyldopa.
Topics: Animals; Benzothiazoles; Copper; Cysteinyldopa; Hair; Iron; Mammals; Oxidation-Reduction; Pigments, Biological; Thiazoles | 2002 |
Highly specific inactivation of triosephosphate isomerase from Trypanosoma cruzi.
Topics: Animals; Benzothiazoles; Cysteine; Dimerization; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Models, Chemical; Protein Binding; Thiazoles; Triose-Phosphate Isomerase; Trypanosoma cruzi | 2002 |
Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay.
Topics: Benzothiazoles; Blotting, Western; Cell Line; Electrophoresis, Polyacrylamide Gel; Exons; Fluorescent Antibody Technique, Indirect; Humans; Huntingtin Protein; Huntington Disease; Microscopy, Electron; Nerve Tissue Proteins; Nuclear Proteins; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles | 2002 |
Synthesis and anticonvulsant activity of 3-(6-substituted-benzothiazol-2-yl)-6-phenyl-[1, 3]-xazinane-2-thiones.
Topics: Animals; Anticonvulsants; Benzothiazoles; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Convulsants; Electroshock; Female; Male; Mice; Molecular Weight; Pentylenetetrazole; Postural Balance; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles | 2002 |
Pyrrolylbenzothiazole derivatives as aldose reductase inhibitors.
Topics: Aldehyde Reductase; Benzothiazoles; Enzyme Inhibitors; Kinetics; Molecular Structure; Pyrroles; Thiazoles | 2002 |
Benzothiazole degradation by Rhodococcus pyridinovorans strain PA: evidence of a catechol 1,2-dioxygenase activity.
Topics: Benzothiazoles; Biodegradation, Environmental; Catechol 1,2-Dioxygenase; Chromatography, High Pressure Liquid; Dioxygenases; Magnetic Resonance Spectroscopy; Oxygenases; Rhodococcus; Thiazoles | 2002 |
Development of novel copper(II) complexes of benzothiazole- N-sulfonamides as protective agents against superoxide anion. Crystal structures of [Cu( N-2-(4-methylbenzothiazole)benzenesulfonamidate)(2)(py)(2)] and [Cu( N-2-(6-nitrobenzothiazole)naphthalene
Topics: Antioxidants; Benzothiazoles; Cell Respiration; Copper; Crystallization; Crystallography, X-Ray; Models, Molecular; Molecular Mimicry; Organometallic Compounds; Oxidative Stress; Saccharomyces cerevisiae; Sulfonamides; Superoxide Dismutase; Superoxides; Thiazoles; Vitamin K 3 | 2003 |
Identification of a water pollutant, 2-amino-6,7-dichlorobenzothiazole, at a river near a textile industrial complex in Korea.
Topics: Benzothiazoles; Chromatography, High Pressure Liquid; Environmental Monitoring; Korea; Mutagenicity Tests; Salmonella; Textile Industry; Thiazoles; Water Pollutants, Chemical | 2003 |
Development and application of an LC-MS method to determine possible migration of mercaptobenzothiazole, benzothiazole and related vulcanization residues from rubber used in contact with food and drink.
Topics: Benzothiazoles; Beverages; Chromatography, Liquid; Food Contamination; Food Handling; Hot Temperature; Humans; Infant; Infant Food; Mass Spectrometry; Rubber; Thiazoles | 2003 |
Design, synthesis and biological evaluation of benzimidazole/benzothiazole and benzoxazole derivatives as cyclooxygenase inhibitors.
Topics: Benzimidazoles; Benzothiazoles; Benzoxazoles; Blood; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Heterocyclic Compounds; Humans; Inhibitory Concentration 50; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Thiazoles | 2003 |
The SA-dependent defense pathway is active against different pathogens in tomato and tobacco.
Topics: Benzothiazoles; Botrytis; Immunity, Innate; Mitosporic Fungi; Nicotiana; Plant Diseases; Plant Epidermis; Plant Leaves; Plants, Genetically Modified; Salicylic Acid; Solanum lycopersicum; Thiazoles | 2002 |
PMHS-mediated couplings of alkynes or benzothiazoles with various electrophiles: application to the synthesis of (-)-akolactone A.
Topics: Alkynes; Benzothiazoles; Catalysis; Indicators and Reagents; Lactones; Molecular Conformation; Monosaccharides; Siloxanes; Thiazoles | 2003 |
Application of thin-layer chromatographic data in quantitative structure-activity relationship assay of thiazole and benzothiazole derivatives with H1-antihistamine activity. I.
Topics: Benzothiazoles; Chromatography, Thin Layer; Histamine H1 Antagonists; Quantitative Structure-Activity Relationship; Thiazoles | 2003 |
Application of thin-layer chromatographic data in quantitative structure-activity relationship assay of thiazole and benzothiazole derivatives with H1-antihistamine activity. II.
Topics: Benzothiazoles; Chromatography, Thin Layer; Histamine H1 Antagonists; Quantitative Structure-Activity Relationship; Thiazoles | 2003 |
Antitumor benzothiazoles. Frontier molecular orbital analysis predicts bioactivation of 2-(4-aminophenyl)benzothiazoles to reactive intermediates by cytochrome P4501A1.
Topics: Antineoplastic Agents; Benzothiazoles; Binding Sites; Biotransformation; Breast Neoplasms; Cations; Cell Death; Cytochrome P-450 CYP1A1; DNA Adducts; Dose-Response Relationship, Drug; Female; Humans; Hydrocarbons, Fluorinated; Models, Molecular; Oxidation-Reduction; Thiazoles; Tumor Cells, Cultured | 2003 |
Synthesis and PDF inhibitory activities of novel benzothiazolylidenehydroxamic acid derivatives.
Topics: Amidohydrolases; Benzothiazoles; Binding Sites; Enzyme Inhibitors; Hydroxamic Acids; Thiazoles | 2003 |
Synthesis of some new benzothiazole derivatives as potential antimicrobial and antiparasitic agents.
Topics: Animals; Anti-Infective Agents; Antinematodal Agents; Antiparasitic Agents; Benzothiazoles; Crystallization; Dose-Response Relationship, Drug; Indicators and Reagents; Intestines; Mice; Schistosoma; Schistosomiasis; Schistosomicides; Thiazoles; Trichinella; Trichinellosis | 2003 |
Experimental studies on drug resistance of dermatophytes. I. The development of drug resistance of Trichophyton mentagrophytes and Microsporum lanosum to undecylenic acid and 2-dimethyl amino-6-(beta-di-ethylaminoethoxy) benzothiazole dihydrochloride (a
Topics: Antifungal Agents; Arthrodermataceae; Benzothiazoles; Drug Resistance; Microsporum; Thiazoles; Trichophyton; Undecylenic Acids | 1955 |
Fundamental pathological changes and their modification by chemotherapy in experimental tuberculosis (report I). The therapeutic effect of various anti-tuberculous compounds containing several benzothiazole derivatives. I.
Topics: Benzothiazoles; Thiazoles; Tuberculosis | 1957 |
[The fundamental pathologic finding and its modification by chemotherapy in experimental tuberculosis. II. On the therapeutic effect of various anti-tuberculous compounds containing several benzothiazole derivatives].
Topics: Benzothiazoles; Isoniazid; Streptomycin; Thiazoles; Tuberculosis | 1957 |
[Fundamental pathological findings and their modification by chemotherapy in experimental tuberculosis. III. On the therapeutic effect of various anti-tuberculous compounds containing several benzothiazole derivatives].
Topics: Benzothiazoles; Thiazoles; Tuberculosis | 1957 |
[STUDIES ON ANTIBILHARZIAL DRUGS. II. SYNTHESIS OF DERIVATIVES OF BENZOTHIAZOLE AND BENZIMIDAZOLE].
Topics: Antiprotozoal Agents; Benzimidazoles; Benzothiazoles; Chemistry, Pharmaceutical; Mice; Pharmacology; Research; Schistosomiasis; Thiazoles | 1964 |
Zinc complexes of benzothiazole-derived Schiff bases with antibacterial activity.
Topics: Anti-Bacterial Agents; Benzothiazoles; Escherichia coli; Ligands; Models, Chemical; Protein Binding; Pseudomonas aeruginosa; Schiff Bases; Spectrophotometry, Infrared; Staphylococcus aureus; Thiazoles; Zinc | 2003 |
Environmental impact of highway construction and repair materials on surface and ground waters. Case study: crumb rubber asphalt concrete.
Topics: Animals; Benzothiazoles; Biodegradation, Environmental; Chlorophyta; Conservation of Natural Resources; Construction Materials; Daphnia; Hydrocarbons; Metals, Heavy; Risk Assessment; Rubber; Soil Pollutants; Thiazoles; Toxicity Tests; Transportation; Volatilization; Water Pollutants | 2003 |
2-Amino-1,3-benzothiazole-ethyl coumarin-3-carboxylate (1/1).
Topics: Benzothiazoles; Coumarins; Crystallography, X-Ray; Hydrogen Bonding; Molecular Structure; Thiazoles | 2003 |
Synthesis and biological evaluation of benzo[d]isothiazole, benzothiazole and thiazole Schiff bases.
Topics: Animals; Anti-HIV Agents; Anti-Infective Agents; Antineoplastic Agents; Benzothiazoles; Cattle; Cell Division; Cell Line, Tumor; Drug Evaluation, Preclinical; HIV-1; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Schiff Bases; T-Lymphocytes; Thiazoles | 2003 |
A new approach to the synthesis of benzothiazole, benzoxazole, and pyridine nucleosides as potential antitumor agents.
Topics: Antineoplastic Agents; Benzothiazoles; Benzoxazoles; Cell Line, Tumor; Humans; Nucleosides; Pyridines; Thiazoles | 2003 |
Synthesis and SAR of 2-arylbenzoxazoles, benzothiazoles and benzimidazoles as inhibitors of lysophosphatidic acid acyltransferase-beta.
Topics: Acyltransferases; Benzimidazoles; Benzothiazoles; Benzoxazoles; Cell Line, Tumor; Enzyme Inhibitors; Humans; Structure-Activity Relationship; Thiazoles | 2004 |
Synthesis, crystal structure and antiproliferative evaluation of some new substituted benzothiazoles and styrylbenzothiazoles.
Topics: Benzothiazoles; Cell Division; Cell Line; Cell Line, Tumor; Crystallization; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fibroblasts; Growth Inhibitors; HeLa Cells; Humans; Thiazoles | 2004 |
Density functional theory and ab initio studies of geometry, electronic structure and vibrational spectra of novel benzothiazole and benzotriazole herbicides.
Topics: Benzothiazoles; Data Interpretation, Statistical; Herbicides; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thiazoles; Triazoles | 2004 |
Synthesis and antileishmanial activity of (1,3-benzothiazol-2-yl) amino-9-(10H)-acridinone derivatives.
Topics: Acridines; Acridones; Animals; Antiprotozoal Agents; Benzothiazoles; Humans; Leishmania infantum; Thiazoles | 2004 |
Development of a PET/SPECT agent for amyloid imaging in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Benzothiazoles; Binding, Competitive; Brain; Carbon Radioisotopes; Cerebellum; Disease Models, Animal; Female; Frontal Lobe; Humans; Iodine Radioisotopes; Metabolic Clearance Rate; Mice; Mice, Transgenic; Molecular Structure; Plaque, Amyloid; Positron-Emission Tomography; Radioligand Assay; Thiazoles; Tomography, Emission-Computed, Single-Photon | 2004 |
Synthesis and evaluation of antitumor activity of 2- and 6-[(1,3-benzothiazol-2-yl)aminomethyl]-5,8-dimethoxy-1,4-naphthoquinone derivatives.
Topics: Animals; Antineoplastic Agents; Benzothiazoles; Chlorocebus aethiops; Drug Screening Assays, Antitumor; Leukemia L1210; Male; Mice; Mice, Inbred ICR; Naphthoquinones; Sarcoma 180; Thiazoles; Vero Cells | 2004 |
Occurrence of benzothiazoles in municipal wastewater and their fate in biological treatment.
Topics: Benzothiazoles; Bioreactors; Cities; Mass Spectrometry; Membranes, Artificial; Methylation; Sewage; Thiazoles; Time Factors; Waste Disposal, Fluid; Water Purification | 2004 |
Activity of benzothiazoles and chemical derivatives on Plasmodium falciparum.
Topics: Adolescent; Aged; Animals; Antimalarials; Benzothiazoles; Cell Line; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Life Cycle Stages; Malaria; Malaria, Falciparum; Mice; Mice, Inbred BALB C; Monocytes; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Thiazoles | 2004 |
Synthesis of potent and selective inhibitors of Candida albicans N-myristoyltransferase based on the benzothiazole structure.
Topics: Acyltransferases; Antifungal Agents; Benzothiazoles; Candida albicans; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Thiazoles | 2005 |
Benzothiazolium compounds: novel classes of inhibitors that suppress the nitric oxide production in RAW264.7 cells stimulated by LPS/IFNgamma.
Topics: Animals; Benzothiazoles; Cell Line, Tumor; Enzyme Inhibitors; Interferon-gamma; Lipopolysaccharides; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Thiazoles | 2005 |
Structural modifications and antimicrobial activity of N-cycloalkenyl-2-acylalkylidene-2,3-dihydro-1,3-benzothiazoles.
Topics: Anti-Bacterial Agents; Antifungal Agents; Benzothiazoles; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Thiazoles | 2005 |
Evaluation of potential molecular markers for urban stormwater runoff.
Topics: Benzothiazoles; Chrysenes; Cities; Environmental Monitoring; Geologic Sediments; Polycyclic Aromatic Hydrocarbons; Rain; Seasons; South Carolina; Sulfur Compounds; Thiazoles; Thiophenes; Time Factors; Water; Water Pollutants, Chemical; Water Supply | 2004 |
Synthesis and biological evaluation of benzothiazole derivatives as potent antitumor agents.
Topics: Animals; Antineoplastic Agents; Benzamides; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Drug Design; Female; Humans; Lung Neoplasms; Mice; Molecular Structure; Structure-Activity Relationship; Thiazoles; Time Factors; Xenograft Model Antitumor Assays | 2005 |
Multiple ligand binding sites on A beta(1-40) fibrils.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Binding Sites; Congo Red; Fluorescent Dyes; Humans; Ibuprofen; Ligands; Models, Chemical; Molecular Structure; Naproxen; Peptide Fragments; Protein Binding; Thiazoles | 2005 |
Evaluation of the benzothiazole aggregation inhibitors riluzole and PGL-135 as therapeutics for Huntington's disease.
Topics: Animals; Benzothiazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Genotype; Huntington Disease; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Neuroprotective Agents; Organ Culture Techniques; Riluzole; Thiazoles | 2006 |
Synthesis of novel benzoic acid derivatives with benzothiazolyl subunit and evaluation as aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Benzoic Acid; Benzothiazoles; Cattle; Enzyme Inhibitors; In Vitro Techniques; Lens, Crystalline; Molecular Structure; Structure-Activity Relationship; Thiazoles | 2005 |
A novel one-pot three-component reaction: synthesis of triheterocyclic 4H-pyrimido[2,1-b]benzazoles ring systems.
Topics: Benzimidazoles; Benzothiazoles; Heterocyclic Compounds; Models, Molecular; Molecular Conformation; Pyrimidines; Thiazoles | 2005 |
Solid phase combinatorial synthesis of benzothiazoles and evaluation of topoisomerase II inhibitory activity.
Topics: Benzothiazoles; Catalysis; Cell Line, Tumor; Cell Proliferation; Combinatorial Chemistry Techniques; DNA Topoisomerases, Type II; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Molecular Structure; Structure-Activity Relationship; Thiazoles; Topoisomerase II Inhibitors | 2006 |
Benzothiazole derivatives as novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Benzothiazoles; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Microsomes, Liver; Protein Conformation; Structure-Activity Relationship; Thiazoles | 2006 |
Synthesis, antiproliferative and antifungal activities of some 2-(2,4-dihydroxyphenyl)-4H-3,1-benzothiazines.
Topics: Antifungal Agents; Antineoplastic Agents; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Cyclization; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Models, Molecular; Thiazoles; X-Ray Diffraction | 2006 |
Synthesis, X-ray crystallographic analysis, and antitumor activity of N-(benzothiazole-2-yl)-1-(fluorophenyl)-O,O-dialkyl-alpha-aminophosphonates.
Topics: Antineoplastic Agents; Benzothiazoles; Cell Proliferation; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Lung Neoplasms; Magnetic Resonance Spectroscopy; Male; Melanoma; Organophosphonates; Prohibitins; Prostatic Neoplasms; Skin Neoplasms; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured | 2006 |
Structural differences in triosephosphate isomerase from different species and discovery of a multitrypanosomatid inhibitor.
Topics: Animals; Benzothiazoles; Chickens; Dose-Response Relationship, Drug; Entamoeba histolytica; Enzyme Activation; Fluorescence; Humans; Leishmania mexicana; Species Specificity; Thiazoles; Time Factors; Triose-Phosphate Isomerase; Trypanosoma brucei brucei; Trypanosoma cruzi | 2006 |
Collision-energy-resolved Penning ionization electron spectroscopy of thiazole and benzothiazole: study of ionic states and anisotropic interactions between a metastable He(23S) atom and hetero cyclic compounds.
Topics: Benzothiazoles; Helium; Ions; Quantum Theory; Spectrum Analysis; Thiazoles | 2006 |
11C-labelled PIB analogues as potential tracer agents for in vivo imaging of amyloid beta in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Benzothiazoles; Brain; Carbon Radioisotopes; Fluorine Radioisotopes; Humans; Hydroxides; Isomerism; Mice; Radioactive Tracers; Staining and Labeling; Thiazoles | 2009 |
Hybrid pharmacophore design and synthesis of isatin-benzothiazole analogs for their anti-breast cancer activity.
Topics: Antineoplastic Agents; Benzothiazoles; Breast Neoplasms; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Indoles; Isatin; Thiazoles | 2009 |
Amyloid-binding small molecules efficiently block SEVI (semen-derived enhancer of virus infection)- and semen-mediated enhancement of HIV-1 infection.
Topics: Amyloid; Animals; Benzothiazoles; Cell Line, Tumor; Cells, Cultured; Competitive Bidding; Dose-Response Relationship, Drug; Flow Cytometry; HIV-1; Humans; Jurkat Cells; Kinetics; Male; Molecular Structure; Protein Binding; Semen; Thiazoles; Virion; Virus Attachment | 2010 |
4-(6-Diethylaminohexylamino)-6-methoxy-benzothiazole (SN 15, 295).
Topics: Benzothiazoles; Humans; Quinolines; Thiazoles | 1946 |
Ligand polarizability contributes to tau fibril binding affinity.
Topics: Alzheimer Disease; Benzothiazoles; Binding Sites; Humans; Indoles; Ligands; Oxindoles; Phenothiazines; Protein Binding; tau Proteins; Thiazoles | 2011 |
New benzothiazole/thiazole-containing hydroxamic acids as potent histone deacetylase inhibitors and antitumor agents.
Topics: Animals; Antineoplastic Agents; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; MCF-7 Cells; Mice; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship; Thiazoles | 2013 |
Design and synthesis of novel 4-benzothiazole amino quinazolines Dasatinib derivatives as potential anti-tumor agents.
Topics: Antineoplastic Agents; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dasatinib; Dose-Response Relationship, Drug; Drug Design; HCT116 Cells; Humans; Inhibitory Concentration 50; K562 Cells; Models, Chemical; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; Quinazolines; src-Family Kinases; Thiazoles; U937 Cells | 2013 |
Amyloid tracers detect multiple binding sites in Alzheimer's disease brain tissue.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Aniline Compounds; Apolipoprotein E4; Benzothiazoles; Binding Sites; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Peptide Fragments; Postmortem Changes; Radionuclide Imaging; Thiazoles; Tissue Distribution; Tritium | 2013 |
Molecular rotor-based fluorescent probe for selective recognition of hybrid G-quadruplex and as a K+ sensor.
Topics: Benzene; Benzothiazoles; Fluorescent Dyes; G-Quadruplexes; Potassium; Rotation; Spectrometry, Fluorescence; Substrate Specificity; Thiazoles; Transition Temperature | 2014 |
A combination of quantitative marinating and Maillard reaction to enhance volatile flavor in Chinese marinated chicken.
Topics: Animals; Beijing; Benzothiazoles; Chickens; Condiments; Cysteine; Flavoring Agents; Food Quality; Furans; Humans; Maillard Reaction; Meat; Molecular Structure; Salts; Sensation; Statistics as Topic; Taste; Thiamine; Thiazoles; Volatile Organic Compounds; Xylose | 2017 |
Biological Activity Evaluation of Novel 1,2,4-Triazine Derivatives Containing Thiazole/Benzothiazole Rings.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzothiazoles; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; MCF-7 Cells; Mice; NIH 3T3 Cells; Structure-Activity Relationship; Thiazoles; Triazines | 2017 |
Synthesis and biological evaluation of aminomethyl and alkoxymethyl derivatives as carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Benzothiazoles; Benzoxazoles; Butyrylcholinesterase; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship; Thiazoles | 2017 |
Synthesis of 2-Arylbenzothiazole and 2-Arylthiazole Derivatives via a Ru-Catalyzed
Topics: Benzothiazoles; Catalysis; Humans; Molecular Structure; Nitrates; Ruthenium; Stereoisomerism; Thiazoles; Trypanocidal Agents; Trypanosomiasis, African | 2019 |
Design, Synthesis and Biological Evaluation of Benzo[D]Thiazole with Dimethylpyrazol Derivatives.
Topics: Animals; Anticonvulsants; Benzothiazoles; Cell Line, Tumor; GABA Agents; Humans; Mice; Seizures; Synaptic Transmission; Thiazoles | 2019 |
CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer.
Topics: Alternative Splicing; Animals; Apoptosis; Benzothiazoles; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin-Dependent Kinases; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; Mice, Nude; Molecular Targeted Therapy; Neoplasm Invasiveness; Prostatic Neoplasms; Protein Kinase Inhibitors; RNA-Seq; Thiazoles; Xenograft Model Antitumor Assays | 2021 |