Page last updated: 2024-08-23

benzonidazole and podophyllotoxin

benzonidazole has been researched along with podophyllotoxin in 68 studies

Research

Studies (68)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	15 (22.06)	29.6817
2010's	47 (69.12)	24.3611
2020's	6 (8.82)	2.80

Authors

Authors	Studies
Croft, SL; Gamenara, D; Grady, S; Heinzen, H; Kendrick, H; Moyna, G; Moyna, P; Ren, H; Yardley, V	1
Brun, R; Cimanga, K; Dommisse, R; Hostyn, S; Kaiser, M; Lemière, G; Maes, BU; Mátyus, P; Pieters, L; Van Miert, S; Vlietinck, A	1
Bauer, H; Davioud-Charvet, E; Krauth-Siegel, RL; Lee, B; Melchers, J; Rattray, L; Ruppert, T; Yardley, V	1
Brun, R; Buendía, AM; Gilbert, IH; Kaiser, M; Mc Carthy, OK; Pacanowska, DG; Ruiz-Perez, LM; Schipani, A	1
Croft, SL; Gilbert, IH; Gonzalez-Pacanowska, D; Gros, L; Jimenez, CJ; Little, S; Lorente, SO; Rattray, L; Ruiz-Perez, LM; Wharton, H; Yardley, V	1
Ahua, KM; Brun, R; Diallo, D; Hay, AE; Hostettmann, K; Ioset, JR	1
Bringmann, G; Brun, R; Kaiser, M; Neumann, S	1
Brun, R; Carballeira, NM; Linden, A; O'Neill, R; Perozzo, R; Rüedi, P; Tasdemir, D; Tonge, PJ; Topaloglu, B; Zhang, X	1
Brun, R; Gunzenhauser, S; Senn, M; Séquin, U	1
Brun, R; Kaiser, M; Kuettel, S; Perozzo, R; Scapozza, L; Zambon, A	1
Arai, C; Brun, R; Ge, JF; Ihara, M; Kaiser, M; Wittlin, S	1
Brun, R; Kehraus, S; König, GM; Krick, A; Pontius, A	1
Baell, JB; Brun, R; Charman, WN; Fairlamb, AH; Holloway, GA; Kaiser, M; Kostewicz, E; Novello, PM; Parisot, JP; Richardson, J; Street, IP; Watson, KG	1
Bolognesi, ML; Bongarzone, S; Brun, R; Cavalli, A; Lizzi, F; Luise Krauth-Siegel, R	1
Brun, R; Cos, P; Dhooghe, L; Dommisse, R; Hajós, G; Hostyn, S; Kaiser, M; Lemière, G; Maes, BU; Maes, L; Mátyus, P; Nagy, I; Pieters, L; Riedl, Z; Tapolcsányi, P; Van Baelen, G	1
Brun, R; Lusvarghi, S; Mazzieri, MR; Pagliero, RJ; Pierini, AB	1
Armstrong, T; Baell, JB; Holloway, GA; Novello, PM; Parisot, JP; Street, IP; Thompson, RC; Watson, KG	1
Amade, P; Cachet, N; Kaiser, M; Regalado, EL; Tasdemir, D; Thomas, OP	1
Baumann, K; Bischof, SK; Bringmann, G; Brun, R; Dreher, J; Gulder, T; Kaiser, M; Moll, H; Müller, S; Stich, A; Winter, C	1
Brun, R; Carballeira, NM; Herman, R; Kappe, SH; Lauinger, IL; Perozzo, R; Sanabria, D; Tarun, A; Tasdemir, D; Zloh, M	1
Bourguet-Kondracki, ML; Copp, BR; Finlayson, R; Harper, JL; Kaiser, M; Page, MJ; Pearce, AN; Webb, VL	1
Gerth, K; Jansen, R; Mohr, KI; Müller, R; Okanya, PW	1
Chan, ST; Copp, BR; Kaiser, M; Page, MJ; Pearce, AN	1
Brun, R; Ge, JF; Ihara, M; Kaiser, M; Liu, BQ; Shi, XL; Wittlin, S	1
Anizon, F; Bouchikhi, F; Brun, R; Moreau, P	1
Brun, R; Huang, TL; Kaiser, M; Mayence, A; Vanden Eynde, JJ; Yarlett, N	1
Dürüst, Y; Kaiser, M; Karakuş, H; Tasdemir, D	1
Boshoff, HI; Boyd, PD; Copp, BR; Kaiser, M; McCracken, ST	1
Bettis, S; Brun, R; Fomovska, A; Huang, Q; Kaiser, M; Kozikowski, AP; McLeod, R; Mui, E; Pieroni, M; Stec, J; Witola, WH	1
Bloomer, WD; Chatelain, E; Ioset, JR; Kaiser, M; McKenzie, C; Papadopoulou, MV; Rosenzweig, HS; Wilkinson, SR	1
Balaña-Fouce, R; Carballeira, NM; Cartagena, M; Prada, CF; Reguera, RM; Sanabria, D; Tasdemir, D	1
Belluti, F; Bergamini, C; Bolognesi, ML; Brun, R; Hall, DG; Kaiser, M; Krauth-Siegel, RL; Lizzi, F; López-Sánchez, A; Rivas, L; Veronesi, G	1
Copp, BR; Kaiser, M; Liew, LP	1
El Sayed, I; Inokuchi, T; Kaiser, M; Lu, WJ; Maeda, T; Mei, ZW; Pang, CQ; Peng, W; Wang, L	1
Arafa, RK; Boykin, DW; Brun, R; Ismail, MA; Jones, SK; Pandharkar, T; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA; Zhu, X	1
Almohaywi, B; Avery, VM; Baell, JB; Campbell, M; Charman, SA; Ferrins, L; Hyland, C; Jones, AJ; Kaiser, M; Rahmani, R; Ryan, E; Smith, J; Sykes, ML; Teston, E; White, KL; Yin, J	1
Brun, R; Harel, D; Prinz, H; Schepmann, D; Schmidt, TJ; Wünsch, B	1
Batzer, A; Bode, HB; Chantratita, N; Grundmann, F; Kaiser, M; Kurz, M; Schiell, M; Thanwisai, A	1
Botta, B; Brun, R; Costi, R; De Vita, D; Di Santo, R; Friggeri, L; Kaiser, M; Moraca, F; Scipione, L; Tortorella, S; Zamperini, C	1
Boykin, DW; Brun, R; Liu, ZY; Wenzler, T; Zhu, X	1
Avery, VM; Baell, JB; Bergström, CA; Charman, SA; Ferrins, L; Gazdik, M; Jones, AJ; Kaiser, M; Rahmani, R; Ryan, E; Sykes, ML; Varghese, S; White, KL	1
Bode, HB; Kaiser, M; Nollmann, FI; Reimer, D; Schultz, K	1
Ambuehl, C; Breant, L; Christen, P; Cretton, S; Cuendet, M; Ebrahimi, SN; Hamburger, M; Kaiser, M; Karimou, S; Marcourt, L; Perozzo, R; Pourrez, L	1
Battistuzzi, G; Giannini, G	1
Battistuzzi, G; Giannini, G; Vignola, D	1
Dardonville, C; Kaiser, M; Montalvo-Quirós, S; Taladriz-Sender, A	1
Bergamini, C; Bolognesi, ML; Brun, R; Cavalli, A; Falchi, F; Fato, R; Kaiser, M; Molina, MT; Prati, F	1
Alakurtti, S; Brun, R; Jaffe, CL; Kaiser, M; Kopelyanskiy, D; Moreira, VM; Nasereddin, A; Oksman-Caldentey, KM; Pirttimaa, M; Yli-Kauhaluoma, J	1
Bringmann, G; Brun, R; Brünnert, D; Chatterjee, M; Efferth, T; Feineis, D; Kaiser, M; Li, J; Mudogo, V; Seo, EJ; Seupel, R	1
Back, TG; Brun, R; Kaiser, M; Manivannan, S; Pastor, A; Snyder, FF; Tran, HA; Wen, X; Zheng, Z	1
Brun, R; Kaiser, M; Mazzieri, MR; Nieto, MJ; Pagliero, RJ	1
Chianese, G; Erpenbeck, D; Kaiser, M; Luciano, P; Merten, C; Silber, J; Tasdemir, D; Topaloglu, B	1
Awale, S; Bringmann, G; Bruhn, T; Brun, R; Feineis, D; Kaiser, M; Li, J; Mudogo, V; Seupel, R	1
Bringmann, G; Brun, R; Efferth, T; Feineis, D; Kaiser, M; Mudogo, V; Seo, EJ; Tshitenge, DT	1
Aliabadi, A; De Mieri, M; Ebrahimi, SN; Farimani, MM; Hamburger, M; Kaiser, M; Khodaei, B; Moradi, H	1
Brun, R; Calvet, CM; Costi, R; De Leo, A; De Vita, D; Di Santo, R; Jennings, GK; Kaiser, M; Madia, VN; Mäser, P; Messore, A; Pescatori, L; Podust, LM; Saccoliti, F; Scipione, L; Tudino, V	1
Bode, HB; Cai, X; Kaiser, M; Zhao, L	1
Danton, O; Hamburger, M; Kaiser, M; Moridi Farimani, M; Nejad Ebrahimi, S; Neuburger, M; Potterat, O; Ramseyer, J; Salehi, P; Tabefam, M	1
Battista, MR; Brun, R; Calvet, CM; Cirilli, R; Costi, R; De Leo, A; De Vita, D; Di Marco, A; Di Santo, R; Faggi, C; Jennings, GK; Kaiser, M; Madia, VN; Mäser, P; Messore, A; Pepe, G; Pescatori, L; Podust, LM; Saccoliti, F; Scipione, L; Summa, V; Tudino, V	1
Nair, JJ; van Staden, J	1
Awale, S; Bringmann, G; Bruhn, T; Brun, R; Feineis, D; Kaiser, M; Mudogo, V; Schmidt, D; Tshitenge, DT; Würthner, F	1
Al-Harrasi, A; Babanezhad Harikandei, K; Bararjanian, M; Ebrahimi, SN; Kaiser, M; Salehi, P	1
Awori, RM; Bode, HB; Groß, J; Kaiser, M; Opatz, T; Zhao, L	1
Appelqvist, P; Erath, J; Gilbert, IH; Hampton, S; Harrison, JR; Johansson, NG; Kaiser, M; Mathan, V; Pacanowska, DG; Read, KD; Riley, J; Rodriguez, A; Sahlberg, C; Sarkar, S; Stojanovski, L	1
Christen, P; Cretton, S; Cuendet, M; Ebrahimi, SN; Kaiser, M; Karimou, S; Mäser, P	1
Bringmann, G; Feineis, D; Kaiser, M; Lombe, BK; Mudogo, V	1
Börgel, F; Jabor, VAP; Kaiser, M; Krauth-Siegel, RL; Lehmkuhl, K; Nonato, MC; Schepmann, D; Schmidt, TJ; Uth, JF; Wünsch, B	1
Brun, R; Celik, I; Doganc, F; Eren, G; Goker, H; Kaiser, M	1

Reviews

1 review(s) available for benzonidazole and podophyllotoxin

Article	Year
Antiprotozoal alkaloid principles of the plant family Amaryllidaceae. Bioorganic & medicinal chemistry letters, 2019, 10-15, Volume: 29, Issue:20 Topics: Amaryllidaceae; Amaryllidaceae Alkaloids; Antiprotozoal Agents; Diterpenes; Drug Evaluation, Preclinical; Humans; Isoquinolines; Molecular Structure; Phytochemicals; Plant Extracts; Structure-Activity Relationship; Trypanosoma brucei brucei	2019

Other Studies

67 other study(ies) available for benzonidazole and podophyllotoxin

Article	Year
Design, synthesis, and biological evaluation of a series of simple and novel potential antimalarial compounds. Bioorganic & medicinal chemistry letters, 2001, Jul-23, Volume: 11, Issue:14 Topics: Animals; Antimalarials; Benzocycloheptenes; Drug Design; Nitrobenzenes; Oxazines; Plasmodium falciparum; Trypanosoma cruzi	2001
Isoneocryptolepine, a synthetic indoloquinoline alkaloid, as an antiplasmodial lead compound. Journal of natural products, 2005, Volume: 68, Issue:5 Topics: Alkaloids; Animals; Antimalarials; Apocynaceae; Indole Alkaloids; Indoles; Molecular Structure; Plasmodium falciparum; Quinolines; Structure-Activity Relationship	2005
Irreversible inactivation of trypanothione reductase by unsaturated Mannich bases: a divinyl ketone as key intermediate. Journal of medicinal chemistry, 2005, Nov-17, Volume: 48, Issue:23 Topics: Animals; Antimalarials; Antiprotozoal Agents; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Drug Storage; Glutathione; Glutathione Reductase; Humans; Ketones; Leishmania donovani; Magnetic Resonance Spectroscopy; Mannich Bases; NADH, NADPH Oxidoreductases; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thioredoxin-Disulfide Reductase; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2005
Design, synthesis and evaluation of novel uracil amino acid conjugates for the inhibition of Trypanosoma cruzi dUTPase. Bioorganic & medicinal chemistry letters, 2006, Jul-15, Volume: 16, Issue:14 Topics: Acetamides; Amino Acids; Animals; Chagas Disease; Drug Design; Enzyme Inhibitors; Inhibitory Concentration 50; Models, Chemical; Pyrophosphatases; Trypanocidal Agents; Trypanosoma cruzi; Uracil	2006
Evaluation of azasterols as anti-parasitics. Journal of medicinal chemistry, 2006, Oct-05, Volume: 49, Issue:20 Topics: Animals; Antimalarials; Azasteroids; Leishmania donovani; Methyltransferases; Plasmodium falciparum; Stereoisomerism; Sterols; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2006
Limonoid orthoacetates and antiprotozoal compounds from the roots of Pseudocedrela kotschyi. Journal of natural products, 2007, Volume: 70, Issue:1 Topics: Animals; Antiprotozoal Agents; Leishmania donovani; Limonins; Mali; Meliaceae; Molecular Structure; Plant Roots; Plants, Medicinal; Plasmodium falciparum; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2007
Synthesis and antiprotozoal activities of simplified analogs of naphthylisoquinoline alkaloids. European journal of medicinal chemistry, 2008, Volume: 43, Issue:1 Topics: Alkaloids; Animals; Antiprotozoal Agents; Eukaryota; Isoquinolines; Myoblasts, Skeletal	2008
Marine natural products from the Turkish sponge Agelas oroides that inhibit the enoyl reductases from Plasmodium falciparum, Mycobacterium tuberculosis and Escherichia coli. Bioorganic & medicinal chemistry, 2007, Nov-01, Volume: 15, Issue:21 Topics: Agelas; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antimalarials; Bacterial Proteins; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Escherichia coli; Marine Biology; Mycobacterium tuberculosis; Plasmodium falciparum; Protozoan Proteins	2007
Antiprotozoal polyacetylenes from the Tanzanian medicinal plant Cussonia zimmermannii. Journal of natural products, 2007, Volume: 70, Issue:10 Topics: Animals; Antiprotozoal Agents; Araliaceae; Leishmania donovani; Molecular Structure; Plants, Medicinal; Plasmodium falciparum; Polyynes; Tanzania; Trypanosoma brucei rhodesiense	2007
Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives. Journal of medicinal chemistry, 2007, Nov-15, Volume: 50, Issue:23 Topics: Animals; Antimalarials; Leishmania donovani; Morpholines; Plasmodium falciparum; Pyrazoles; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma	2007
Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive 3,7-bis(dialkylamino)phenoxazin-5-ium derivatives. Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12 Topics: Animals; Antimalarials; Antiprotozoal Agents; Chloroquine; Drug Resistance; Leishmania donovani; Oxazines; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2008
Antiprotozoal activities of heterocyclic-substituted xanthones from the marine-derived fungus Chaetomium sp. Journal of natural products, 2008, Volume: 71, Issue:9 Topics: Animals; Antiprotozoal Agents; Bacillus megaterium; Chaetomium; Chlorella; Drug Screening Assays, Antitumor; Escherichia coli; Leishmania donovani; Marine Biology; Microbial Sensitivity Tests; Models, Molecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Trypanosoma cruzi; Xanthones	2008
Trypanothione reductase high-throughput screening campaign identifies novel classes of inhibitors with antiparasitic activity. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7 Topics: Animals; Antiparasitic Agents; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Molecular Structure; NADH, NADPH Oxidoreductases; Structure-Activity Relationship; Trypanosoma; Trypanosomiasis	2009
Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase. Bioorganic & medicinal chemistry letters, 2009, Jun-01, Volume: 19, Issue:11 Topics: Animals; Antiparasitic Agents; Cell Line; Computer Simulation; Drug Design; Enzyme Inhibitors; Glutathione Reductase; Humans; NADH, NADPH Oxidoreductases; Quinazolines; Rats; Structure-Activity Relationship; Trypanosoma cruzi	2009
Structure-activity relationship of antiparasitic and cytotoxic indoloquinoline alkaloids, and their tricyclic and bicyclic analogues. Bioorganic & medicinal chemistry, 2009, Oct-15, Volume: 17, Issue:20 Topics: Animals; Antimalarials; Antineoplastic Agents; Indole Alkaloids; Mice; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship	2009
Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines. Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1 Topics: Animals; Antiprotozoal Agents; Cell Line; Humans; Leishmania donovani; Models, Molecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Infections; Quinolines; Structure-Activity Relationship; Trypanosoma; Trypanosoma cruzi	2010
Discovery of novel and potent benzhydryl-tropane trypanocides highly selective for Trypanosoma cruzi. Bioorganic & medicinal chemistry letters, 2010, Mar-15, Volume: 20, Issue:6 Topics: Animals; Cell Line; Drug Discovery; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi	2010
Antiprotozoal steroidal saponins from the marine sponge Pandaros acanthifolium. Journal of natural products, 2010, Aug-27, Volume: 73, Issue:8 Topics: Animals; Antiprotozoal Agents; Leishmania donovani; Marine Biology; Nuclear Magnetic Resonance, Biomolecular; Oceans and Seas; Plasmodium falciparum; Porifera; Saponins; Steroids; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2010
QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids. European journal of medicinal chemistry, 2010, Volume: 45, Issue:11 Topics: Alkaloids; Animals; Antimalarials; Isoquinolines; Magnetic Resonance Spectroscopy; Models, Molecular; Plasmodium falciparum; Quantitative Structure-Activity Relationship; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared	2010
2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections. Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21 Topics: Alkynes; Antimalarials; Binding Sites; Cell Line, Tumor; Computer Simulation; Erythrocytes; Fatty Acid Synthase, Type II; Fatty Acids, Unsaturated; Humans; Kinetics; Liver; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins	2010
Didemnidines A and B, indole spermidine alkaloids from the New Zealand ascidian Didemnum sp. Journal of natural products, 2011, Apr-25, Volume: 74, Issue:4 Topics: Animals; Antiprotozoal Agents; Indole Alkaloids; Leishmania donovani; Molecular Structure; New Zealand; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Spermidine; Structure-Activity Relationship; Trypanosoma; Urochordata	2011
Marinoquinolines A-F, pyrroloquinolines from Ohtaekwangia kribbensis (Bacteroidetes). Journal of natural products, 2011, Apr-25, Volume: 74, Issue:4 Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Antineoplastic Agents; Bacteroidetes; Drug Screening Assays, Antitumor; Female; Humans; India; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Pyrroles; Quinolines	2011
Antimalarial β-carbolines from the New Zealand ascidian Pseudodistoma opacum. Journal of natural products, 2011, Sep-23, Volume: 74, Issue:9 Topics: Animals; Antimalarials; Carbolines; Chloroquine; Drug Resistance; Molecular Structure; New Zealand; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Stereoisomerism; Urochordata	2011
Synthesis and in vitro antiprotozoal activities of 5-phenyliminobenzo[a]phenoxazine derivatives. Bioorganic & medicinal chemistry letters, 2011, Oct-01, Volume: 21, Issue:19 Topics: Animals; Antimalarials; Antiprotozoal Agents; Drug Design; Inhibitory Concentration 50; Leishmania donovani; Malaria; Models, Chemical; Molecular Structure; Myoblasts; Oxazines; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyridinium Compounds; Rats; Structure-Activity Relationship; Thiazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2011
Biological evaluation of glycosyl-isoindigo derivatives against the pathogenic agents of tropical diseases (malaria, Chagas disease, leishmaniasis and human African trypanosomiasis). Bioorganic & medicinal chemistry letters, 2011, Nov-01, Volume: 21, Issue:21 Topics: Animals; Antiprotozoal Agents; Drug Evaluation, Preclinical; Humans; Protozoan Infections	2011
Bis(oxyphenylene)benzimidazoles: a novel class of anti-Plasmodium falciparum agents. Bioorganic & medicinal chemistry, 2011, Dec-15, Volume: 19, Issue:24 Topics: Animals; Antimalarials; Benzimidazoles; Cell Line; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats	2011
Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3]triazoles. European journal of medicinal chemistry, 2012, Volume: 48 Topics: Animals; Antiprotozoal Agents; Cell Line; Eukaryota; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Structure; Oxadiazoles; Protozoan Infections; Pyrroles; Rats; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Triazoles	2012
Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers. Bioorganic & medicinal chemistry, 2012, Feb-15, Volume: 20, Issue:4 Topics: Antimalarials; Antitubercular Agents; Coumarins; Dimerization; Fatty Acids, Monounsaturated; Inhibitory Concentration 50; Leishmania donovani; Light; Molecular Structure; Plasmodium falciparum; Pyrones	2012
Synthesis, biological evaluation, and structure-activity relationships of N-benzoyl-2-hydroxybenzamides as agents active against P. falciparum (K1 strain), Trypanosomes, and Leishmania. Journal of medicinal chemistry, 2012, Apr-12, Volume: 55, Issue:7 Topics: Antimalarials; Benzamides; Imides; Leishmania donovani; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2012
Novel 3-nitro-1H-1,2,4-triazole-based amides and sulfonamides as potential antitrypanosomal agents. Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11 Topics: Amides; Animals; Cell Line; Leishmania donovani; Nitro Compounds; Nitroreductases; Parasitic Sensitivity Tests; Prodrugs; Rats; Structure-Activity Relationship; Sulfonamides; Triazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi	2012
2-Alkynoic fatty acids inhibit topoisomerase IB from Leishmania donovani. Bioorganic & medicinal chemistry letters, 2012, Oct-01, Volume: 22, Issue:19 Topics: Alkynes; Animals; Antiprotozoal Agents; Cell Line; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Humans; Leishmania donovani; Macrophages; Mice; Mice, Inbred BALB C; Molecular Structure; Parasitic Sensitivity Tests; Rats; Structure-Activity Relationship; Topoisomerase I Inhibitors; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2012
Conjugation of quinones with natural polyamines: toward an expanded antitrypanosomatid profile. Journal of medicinal chemistry, 2012, Dec-13, Volume: 55, Issue:23 Topics: Animals; Leishmania donovani; Polyamines; Quinones; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2012
Discovery and preliminary structure-activity relationship analysis of 1,14-sperminediphenylacetamides as potent and selective antimalarial lead compounds. Bioorganic & medicinal chemistry letters, 2013, Jan-15, Volume: 23, Issue:2 Topics: Acetamides; Animals; Antimalarials; Drug Discovery; Inhibitory Concentration 50; Malaria; Molecular Structure; Plasmodium falciparum; Spermine; Structure-Activity Relationship	2013
Synthesis and in vitro antimalarial testing of neocryptolepines: SAR study for improved activity by introduction and modifications of side chains at C2 and C11 on indolo[2,3-b]quinolines. Journal of medicinal chemistry, 2013, Feb-28, Volume: 56, Issue:4 Topics: Alkaloids; Animals; Antimalarials; Cell Line; Chloroquine; Drug Resistance; Indoles; Malaria; Mice; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Quinolines; Rats; Structure-Activity Relationship	2013
Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives. Journal of medicinal chemistry, 2013, Jul-11, Volume: 56, Issue:13 Topics: Animals; Antiprotozoal Agents; Benzene; Chagas Disease; Female; Leishmania donovani; Mice; Mice, Inbred Strains; Models, Chemical; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyridines; Structure-Activity Relationship; Terphenyl Compounds; Trypanosoma cruzi	2013
3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis. European journal of medicinal chemistry, 2013, Volume: 66 Topics: Anilides; Animals; Humans; Mice; Myoblasts, Skeletal; Rats; Species Specificity; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2013
Natural product derived antiprotozoal agents: synthesis, biological evaluation, and structure-activity relationships of novel chromene and chromane derivatives. Journal of medicinal chemistry, 2013, Sep-26, Volume: 56, Issue:18 Topics: Antiprotozoal Agents; Biological Products; Chemistry Techniques, Synthetic; Chromans; Inhibitory Concentration 50; Structure-Activity Relationship	2013
Antiparasitic chaiyaphumines from entomopathogenic Xenorhabdus sp. PB61.4. Journal of natural products, 2014, Apr-25, Volume: 77, Issue:4 Topics: Animals; Antiparasitic Agents; Bacillus subtilis; Depsipeptides; Escherichia coli; Humans; Inhibitory Concentration 50; Micrococcus luteus; Molecular Structure; Nematoda; Nuclear Magnetic Resonance, Biomolecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Saccharomyces cerevisiae; Thailand; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Xenorhabdus	2014
New Promising Compounds with in Vitro Nanomolar Activity against Trypanosoma cruzi. ACS medicinal chemistry letters, 2013, Jun-13, Volume: 4, Issue:6 Topics:	2013
Synthesis and antiparasitic activity of new bis-arylimidamides: DB766 analogs modified in the terminal groups. European journal of medicinal chemistry, 2014, Aug-18, Volume: 83 Topics: Amides; Animals; Antiparasitic Agents; Cell Line; Chemistry Techniques, Synthetic; Leishmania; Plasmodium falciparum; Rats; Trypanosoma	2014
Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei. Journal of medicinal chemistry, 2014, Aug-14, Volume: 57, Issue:15 Topics: Animals; Benzamides; Cell Line; HEK293 Cells; Humans; Microsomes, Liver; Myoblasts; Pyridines; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense	2014
Xenortide Biosynthesis by Entomopathogenic Xenorhabdus nematophila. Journal of natural products, 2014, Aug-22, Volume: 77, Issue:8 Topics: Chromatography, High Pressure Liquid; Dipeptides; Leishmania; Molecular Structure; Multigene Family; Nuclear Magnetic Resonance, Biomolecular; Parasitic Sensitivity Tests; Plasmodium falciparum; Trypanosoma brucei brucei; Tryptamines; Xenorhabdus	2014
Antitrypanosomal quinoline alkaloids from the roots of Waltheria indica. Journal of natural products, 2014, Oct-24, Volume: 77, Issue:10 Topics: Alkaloids; Animals; Inhibitory Concentration 50; Malvaceae; Mice; Molecular Structure; Niger; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Quinolines; Trypanocidal Agents; Trypanosoma	2014
Exploring in vitro and in vivo Hsp90 inhibitors activity against human protozoan parasites. Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3 Topics: Animals; Antiprotozoal Agents; Cell Line, Tumor; Disease Models, Animal; HSP90 Heat-Shock Proteins; Humans; Mice; Parasitemia; Plasmodium falciparum; Protein Binding; Rats; Triazoles; Trypanosoma brucei rhodesiense	2015
Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite. Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3 Topics: Animals; Antimalarials; Cell Line, Tumor; Dipeptides; Disease Models, Animal; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Malaria; Mice; Parasites; Plasmodium falciparum; Protein Isoforms	2015
Antiprotozoal activity and DNA binding of dicationic acridones. Journal of medicinal chemistry, 2015, Feb-26, Volume: 58, Issue:4 Topics: Acridines; Acridones; Antiprotozoal Agents; Binding Sites; Cations; DNA; Dose-Response Relationship, Drug; Leishmania donovani; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2015
2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile. Journal of medicinal chemistry, 2015, Aug-27, Volume: 58, Issue:16 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Humans; Leishmania donovani; Mice; Mitochondria; Naphthoquinones; Small Molecule Libraries; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2015
Abietane-Type Diterpenoid Amides with Highly Potent and Selective Activity against Leishmania donovani and Trypanosoma cruzi. Journal of natural products, 2016, Feb-26, Volume: 79, Issue:2 Topics: Abietanes; Amides; Chagas Disease; Humans; Inhibitory Concentration 50; Leishmania donovani; Leishmaniasis; Macrophages; Molecular Structure; Nitroimidazoles; Parasitic Sensitivity Tests; Trypanocidal Agents; Trypanosoma cruzi	2016
Dioncophyllines C Journal of natural products, 2017, 02-24, Volume: 80, Issue:2 Topics: Alkaloids; Antimalarials; Antineoplastic Agents; Humans; Isoquinolines; Magnoliopsida; Molecular Structure; Multiple Myeloma; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Structure-Activity Relationship	2017
Synthesis and activity of nucleoside-based antiprotozoan compounds. Bioorganic & medicinal chemistry, 2017, 04-01, Volume: 25, Issue:7 Topics: Animals; Antiprotozoal Agents; Carbon-13 Magnetic Resonance Spectroscopy; Inhibitory Concentration 50; Leishmania donovani; Plasmodium falciparum; Proton Magnetic Resonance Spectroscopy; Spectrophotometry, Infrared; Trypanosoma brucei brucei; Trypanosoma cruzi	2017
Lead selection of antiparasitic compounds from a focused library of benzenesulfonyl derivatives of heterocycles. Bioorganic & medicinal chemistry letters, 2017, 09-01, Volume: 27, Issue:17 Topics: Animals; Antiparasitic Agents; Benzyl Compounds; Dose-Response Relationship, Drug; Heterocyclic Compounds; Leishmania donovani; Molecular Structure; Myoblasts; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2017
Antiprotozoal Linear Furanosesterterpenoids from the Marine Sponge Ircinia oros. Journal of natural products, 2017, 09-22, Volume: 80, Issue:9 Topics: Animals; Antiprotozoal Agents; Furans; Magnetic Resonance Spectroscopy; Molecular Structure; Porifera; Sesquiterpenes; Spectroscopy, Fourier Transform Infrared	2017
Jozilebomines A and B, Naphthylisoquinoline Dimers from the Congolese Liana Ancistrocladus ileboensis, with Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Cell Line. Journal of natural products, 2017, 10-27, Volume: 80, Issue:10 Topics: Algorithms; Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Congo; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Isoquinolines; Leishmania donovani; Magnoliopsida; Molecular Structure; Naphthalenes; Nuclear Magnetic Resonance, Biomolecular; Pancreatic Neoplasms; Plasmodium falciparum; Rats; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Tumor Cells, Cultured	2017
Mbandakamine-Type Naphthylisoquinoline Dimers and Related Alkaloids from the Central African Liana Ancistrocladus ealaensis with Antiparasitic and Antileukemic Activities. Journal of natural products, 2018, 04-27, Volume: 81, Issue:4 Topics: Africa, Central; Alkaloids; Antimalarials; Antineoplastic Agents, Phytogenic; Antiparasitic Agents; Caryophyllales; Cell Line, Tumor; Humans; Isoquinolines; Naphthalenes; Plasmodium falciparum; Quinolines	2018
Phytochemical Study of Salvia leriifolia Roots: Rearranged Abietane Diterpenoids with Antiprotozoal Activity. Journal of natural products, 2018, 06-22, Volume: 81, Issue:6 Topics: Abietanes; Antimalarials; Antiprotozoal Agents; Inhibitory Concentration 50; Leishmania donovani; Parasitic Sensitivity Tests; Phytochemicals; Plant Extracts; Plant Roots; Plasmodium falciparum; Salvia; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2018
Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents. European journal of medicinal chemistry, 2018, Aug-05, Volume: 156 Topics: Animals; Antiprotozoal Agents; Cell Line; Chagas Disease; Female; Humans; Imidazoles; Inhibitory Concentration 50; Leishmania donovani; Leishmaniasis, Visceral; Malaria, Falciparum; Mice; Mice, Inbred BALB C; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Trypanosomiasis, African	2018
Methionine-Containing Rhabdopeptide/Xenortide-like Peptides from Heterologous Expression of the Biosynthetic Gene Cluster kj12ABC in Escherichia coli. Journal of natural products, 2018, 10-26, Volume: 81, Issue:10 Topics: Amino Acids; Animals; Antineoplastic Agents; Antiparasitic Agents; Escherichia coli; Methionine; Multigene Family; Oligopeptides; Parasites; Rats; Xenorhabdus	2018
Antiprotozoal Isoprenoids from Salvia hydrangea. Journal of natural products, 2018, 12-28, Volume: 81, Issue:12 Topics: Animals; Antiprotozoal Agents; Cell Line; Leishmania donovani; Magnetic Resonance Spectroscopy; Molecular Structure; Plasmodium falciparum; Rats; Salvia; Spectrum Analysis; Terpenes; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2018
Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents. Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3 Topics: Animals; Antiprotozoal Agents; Cytochrome P-450 Enzyme Inhibitors; Drug Design; Drug Evaluation, Preclinical; Humans; Imidazoles; Parasitic Sensitivity Tests; Trypanosoma	2019
Ealamines A-H, a Series of Naphthylisoquinolines with the Rare 7,8'-Coupling Site, from the Congolese Liana Journal of natural products, 2019, 11-22, Volume: 82, Issue:11 Topics: Animals; Antineoplastic Agents, Phytogenic; Antiprotozoal Agents; Caryophyllales; Drug Screening Assays, Antitumor; Humans; Isoquinolines; Leishmania; Molecular Structure; Naphthalenes; Pancreatic Neoplasms; Plant Components, Aerial; Plant Leaves; Plasmodium; Rats; Trypanosoma	2019
Synthesis, in-vitro antiprotozoal activity and molecular docking study of isothiocyanate derivatives. Bioorganic & medicinal chemistry, 2020, 01-01, Volume: 28, Issue:1 Topics: Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Isothiocyanates; Leishmania donovani; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2020
Structure, Biosynthesis, and Bioactivity of Photoditritide from Journal of natural products, 2019, 12-27, Volume: 82, Issue:12 Topics: Anti-Bacterial Agents; Antiprotozoal Agents; Microbial Sensitivity Tests; Micrococcus luteus; Molecular Structure; Photorhabdus; Spectrum Analysis; Trypanosoma brucei rhodesiense	2019
Discovery and Optimization of a Compound Series Active against Journal of medicinal chemistry, 2020, 03-26, Volume: 63, Issue:6 Topics: Animals; Cell Line; Chagas Disease; Drug Discovery; Female; Mice, Inbred BALB C; Molecular Structure; Parasitic Sensitivity Tests; Proof of Concept Study; Quinazolinones; Rats; Small Molecule Libraries; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi	2020
Pyridine-4(1 Journal of natural products, 2020, 11-25, Volume: 83, Issue:11 Topics: Alkaloids; Malvaceae; Molecular Structure; Pyridines; Spectrum Analysis; Trypanocidal Agents; Trypanosoma cruzi	2020
Spirombandakamine A Journal of natural products, 2021, 04-23, Volume: 84, Issue:4 Topics: Alkaloids; Animals; Antiprotozoal Agents; Caryophyllales; Cell Line; Democratic Republic of the Congo; Isoquinolines; Molecular Structure; Phytochemicals; Plant Leaves; Plasmodium falciparum; Rats; Trypanosoma brucei rhodesiense	2021
Synthesis and Biological Evaluation of Natural-Product-Inspired, Aminoalkyl-Substituted 1-Benzopyrans as Novel Antiplasmodial Agents. Journal of medicinal chemistry, 2021, 05-13, Volume: 64, Issue:9 Topics: Alkylation; Animals; Antimalarials; Benzopyrans; Biological Products; Biomimetic Materials; Chemistry Techniques, Synthetic; Erythrocytes; Kinetics; Mice; Plasmodium; Structure-Activity Relationship	2021
Synthesis, in vitro antiprotozoal activity, molecular docking and molecular dynamics studies of some new monocationic guanidinobenzimidazoles. European journal of medicinal chemistry, 2021, Oct-05, Volume: 221 Topics: Antiprotozoal Agents; Benzimidazoles; Cations; Dose-Response Relationship, Drug; Guanidine; Leishmania donovani; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2021