benzonidazole has been researched along with allopurinol in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.53) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 9 (47.37) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Alba-Soto, CD; Briñón, MC; Gualdesi, MS; Novoa, MM; Raviolo, MA; Solana, ME | 1 |
| Bouton, J; Caljon, G; Cardoso Santos, C; Ferreira de Almeida Fiuza, L; Karalic, I; Maes, L; Mazzarella, MA; Soeiro, MNC; Van Calenbergh, S | 1 |
| Caljon, G; Feijens, PB; Hulpia, F; Karalic, I; Lin, C; Maes, L; Matheeussen, A; Van Calenbergh, S | 1 |
| Gallerano, RH; Marr, JJ; Sosa, RR | 1 |
| Aldunate, J; Letelier, ME; Morello, A; Repetto, Y | 1 |
| Gallerano, RH; Meirovich, CI; Montrull, HL; Sosa, RR | 1 |
| Gallerano, RR; Sosa, RR | 1 |
| Colmenarez-Mendoza, HJ; Dávila-Spinetti, DF; Lobo-Vielma, L | 1 |
| A, IZ; B, WA; G, IH; H, IN; H, MT; L, MI; M, LJ; P, JS; V, AM; V, PM | 1 |
| Bestetti, RB; Theodoropoulos, TA | 1 |
| Bartel, LC; Bietto, FM; Castro, JA; de Castro, CR; Montalto de Mecca, M | 1 |
| Bua, J; Bustos, PL; Fichera, LE; Gonzalez, MN; Grosso, NL; Perrone, AE; Postan, M | 1 |
| Albareda, MC; Alvarez, MG; Armenti, AH; Bertocchi, G; Cooley, G; Laucella, SA; Lococo, BE; Perez-Mazliah, DE; Petti, M; Tarleton, RL; Viotti, R | 1 |
| Alarcon, ML; Bua, J; Fichera, LE; Grosso, NL; Laucella, SA; Riarte, A | 1 |
| Benatar, AF; Búa, J; Esteva, MI; Fichera, LE; López Alarcón, M; Prado, NG; Rial, MS; Riarte, AR; Scalise, ML | 1 |
| Assíria, T; Bahia, MT; Diniz, LF; Gonçalves, KR; Mazzeti, AL; Ribeiro, I; WonDollinger, RS | 1 |
| Cardoso Santos, E; Dias Novaes, R; Lima, GDA; Oliveira Silva, R; Santana Nogueira, S; Vilela Gonçalves, R | 1 |
3 review(s) available for benzonidazole and allopurinol
| Article | Year |
|---|---|
[Biochemical bases of the action of anti-chagasic drugs].
Topics: Allopurinol; Animals; Free Radicals; Gentian Violet; Glutathione; Humans; Nifurtimox; Nitroimidazoles; Oxidation-Reduction; Trypanocidal Agents; Trypanosoma cruzi | 1988 |
A systematic review of studies on heart transplantation for patients with end-stage Chagas' heart disease.
Topics: Allopurinol; Chagas Disease; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Neoplasms; Nitroimidazoles; Perioperative Care; Postoperative Complications; Recurrence; Trypanocidal Agents | 2009 |
Monotherapy and combination chemotherapy for Chagas disease treatment: a systematic review of clinical efficacy and safety based on randomized controlled trials.
Topics: Allopurinol; Chagas Disease; Drug Therapy, Combination; Humans; Nitroimidazoles; Randomized Controlled Trials as Topic; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi | 2022 |
3 trial(s) available for benzonidazole and allopurinol
| Article | Year |
|---|---|
Therapeutic efficacy of allopurinol in patients with chronic Chagas' disease.
Topics: Adult; Allopurinol; Chagas Disease; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Nifurtimox; Nitroimidazoles; Trypanocidal Agents | 1990 |
[Allopurinol in the treatment of chronic Chagas' disease].
Topics: Allopurinol; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Nifurtimox; Nitroimidazoles; Trypanocidal Agents | 1985 |
Sequential combined treatment with allopurinol and benznidazole in the chronic phase of Trypanosoma cruzi infection: a pilot study.
Topics: Adult; Allopurinol; Antiprotozoal Agents; B-Lymphocytes; Chagas Disease; Chronic Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Pilot Projects; T-Lymphocytes; Treatment Outcome; Trypanosoma cruzi | 2013 |
13 other study(ies) available for benzonidazole and allopurinol
| Article | Year |
|---|---|
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Synthesis, physicochemical properties of allopurinol derivatives and their biological activity against Trypanosoma cruzi.
Topics: Allopurinol; Animals; Chagas Disease; Chemistry, Physical; Chlorocebus aethiops; Dose-Response Relationship, Drug; Humans; Molecular Structure; Parasitic Sensitivity Tests; Solubility; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells | 2013 |
Revisiting Pyrazolo[3,4-
Topics: Animals; Chagas Disease; Drug Design; Drug Stability; Humans; Leishmania infantum; Male; Mice; Microsomes, Liver; Molecular Structure; Nucleosides; Pyrazoles; Pyrimidines; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2021 |
Exploration of 6-methyl-7-(Hetero)Aryl-7-Deazapurine ribonucleosides as antileishmanial agents.
Topics: Animals; Antiprotozoal Agents; Cricetinae; Leishmania; Leishmaniasis; Mice; Nucleosides; Purine Nucleosides; Purines; Ribonucleosides | 2022 |
[Interventional study in the natural evolution of Chagas disease. Evaluation of specific antiparasitic treatment. Retrospective-prospective study of antiparasitic therapy].
Topics: Adolescent; Adult; Aged; Allopurinol; Antiprotozoal Agents; Chagas Cardiomyopathy; Chagas Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nifurtimox; Nitroimidazoles; Prospective Studies; Retrospective Studies; Time Factors; Treatment Outcome; Trypanocidal Agents | 2000 |
[Mechanisms responsible for myocardial damage progression in chronic Chagas' disease].
Topics: Allopurinol; Antimetabolites; Chagas Cardiomyopathy; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Echocardiography; Electrocardiography; Follow-Up Studies; Humans; Nitroimidazoles; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Time Factors; Trypanocidal Agents | 2005 |
[Part VI. Antiparasitic treatment for Chagas disease].
Topics: Allopurinol; Animals; Chagas Disease; Follow-Up Studies; Humans; Immunocompromised Host; Immunosuppressive Agents; Nifurtimox; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi | 2008 |
Metabolization of nifurtimox and benznidazole in cellular fractions of rat mammary tissue.
Topics: Allopurinol; Animals; Cell Fractionation; Chromatography, High Pressure Liquid; Female; Lipid Peroxidation; Mammary Glands, Animal; Microscopy, Electron, Transmission; Microsomes; Nifurtimox; Nitroimidazoles; Nitroreductases; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Trypanocidal Agents | 2010 |
Trypanosoma cruzi: biological characterization of a isolate from an endemic area and its susceptibility to conventional drugs.
Topics: Allopurinol; Animals; Cell Line; Cells, Cultured; Chagas Disease; Endemic Diseases; Inhibitory Concentration 50; Insect Vectors; Mice; Mice, Inbred C3H; Muscle Cells; Muscles; Nicaragua; Nitroimidazoles; Phylogeny; Rats; Triatoma; Trypanocidal Agents; Trypanosoma cruzi | 2010 |
Combined treatment with benznidazole and allopurinol in mice infected with a virulent Trypanosoma cruzi isolate from Nicaragua.
Topics: Allopurinol; Animals; Antibodies, Protozoan; Chagas Disease; Disease Models, Animal; Drug Therapy, Combination; Mice; Nicaragua; Nitroimidazoles; Survival Analysis; Treatment Outcome; Trypanosoma cruzi | 2013 |
Experimental combination therapy using low doses of benznidazole and allopurinol in mouse models of Trypanosoma cruzi chronic infection.
Topics: Allopurinol; Animals; Chagas Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Nitroimidazoles; Random Allocation; Specific Pathogen-Free Organisms; Trypanocidal Agents; Trypanosoma cruzi | 2019 |
Synergic Effect of Allopurinol in Combination with Nitroheterocyclic Compounds against Trypanosoma cruzi.
Topics: Allopurinol; Animals; Cell Line; Chagas Disease; Humans; Mice; Mortality; Nifurtimox; Nitroimidazoles; Real-Time Polymerase Chain Reaction; Trypanosoma cruzi | 2019 |