benzoic acid and caffeine

benzoic acid has been researched along with caffeine in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (33.33)	18.7374
1990's	8 (15.69)	18.2507
2000's	13 (25.49)	29.6817
2010's	9 (17.65)	24.3611
2020's	4 (7.84)	2.80

Authors

Authors	Studies
Fujita, T; Nakajima, M; Nishioka, T	1
Duffy, EM; Jorgensen, WL	1
Carrupt, PA; Martel, S; Ottaviani, G	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Xu, JL; Yi, DN; Yu, SH	1
Krien, P; Lotte, C; Rallis, M; Rougier, A	1
Camann, WR; Lambert, DH; Murray, RS; Mushlin, PS	1
Conklin, RL; Huether, S; Krueger, GG; Pershing, LK	1
Guy, RH; Maibach, HI; Roskos, KV	1
Carver, MP; Riviere, JE; Williams, PL	1
Li, JQ; Li, SY; Xia, ZY; Zhang, C	1
Akita, I; Ikeda, H; Suwaki, H	1
Lotte, C; Maibach, HI; Rougier, A	1
Lotte, C; Maibach, HI; Rougier, A; Wilson, DR	1
Bronaugh, RL; Franz, TJ	1
Chellquist, EM; Jederberg, WW; Krueger, GG; Reifenrath, WG; Shipwash, EA	1
Khodorov, BI; Khodorova, AB; Mukumov, MR	1
Loeb, AJ	1
Edwards, RC; Voegeli, CJ	1
Doornbos, DA; Rolink, H; Weyland, JW	1
Bronaugh, RL; Congdon, ER; Giles, AL; Stewart, RF	1
Auger, FA; Bélanger, PM; Germain, L; Michel, M	1
Duggan, PF; O'Leary, N; Pembroke, A	1
Lotte, C; Maibach, HI; Rougier, A; Wester, RC	1
Foriers, A; Hamoir, TP; Jimidar, M; Massart, DL	1
Farrell, S; Sirkar, KK	1
HIGUCHI, T; ZUCK, DA	2
Cage, S; Carmichael, PL; Dick, I; Kenyon, S; Korinth, G; Larese, F; Limasset, JC; Maas, WJ; Montomoli, L; Nielsen, JB; Payan, JP; Robinson, E; Sartorelli, P; Schaller, KH; van Burgsteden, JA; van de Sandt, JJ; Wilkinson, SC; Williams, FM	1
Kietzmann, M; Lehr, CM; Meiers, P; Netzlaff, F; Niedorf, F; Schaefer, UF; Stahl, J	1
Dias, M; Hadgraft, J; Lane, ME	2
Nielsen, F; Nielsen, JB; Sørensen, JA	1
Abeliovich, H; Bakalinsky, AT; Hazan, R; Winter, G	1
Bock, U; Haltner-Ukomadu, E; Harms, M; Hoffmann, C; Kaca, M; Lehr, CM; Müller-Goymann, C; Netzlaff, F; Schäfer, U; Tawfik Jalal, M	1
Edelfors, S; Kjaerstad, MB; Knudsen, LE; Mathiesen, L; Mose, T; Nielsen, JB	1
Fu, XC; Pan, XJ	1
Knudsen, LE; Mose, T; Poulsen, MS; Rytting, E	1
Ackermann, K; Borgia, SL; Korting, HC; Mewes, KR; Schäfer-Korting, M	1
Hunsinger, GB; Stern, LA	1
Daschner, A; Frank, O; Hofmann, T; Kreissl, JK	1
Adlhart, C; Fleischli, FD; Morf, F	1
Davies, DJ; Gayes, H; Heylings, JR; Mack, MC; McCarthy, TJ	1
Motoki, A; Nishioka, K; Sano, T; Sugibayashi, K; Todo, H; Uchida, T; Yakumaru, M	1
Csorba, J; Figeczki, T; Gyarmathy, VA; Kiss, J; Medgyesi-Frank, K; Péterfi, A; Posta, J	1
Berger, L; Glass, BD; Llewelyn, VK	4
Do, LHD; Law, RM; Maibach, HI	1
Azzouz, O; Cruz-Cabeza, AJ; Edkins, K; Shen, Y	1

Reviews

1 review(s) available for benzoic acid and caffeine

Article	Year
Dose response effect of chemical surface concentration on percutaneous penetration in human: In vivo + in vitro. Regulatory toxicology and pharmacology : RTP, 2022, Volume: 132 Topics: Administration, Cutaneous; Benzoic Acid; Caffeine; Humans; Skin; Skin Absorption	2022

Trials

1 trial(s) available for benzoic acid and caffeine

Article	Year
Effects of oral caffeine on postdural puncture headache. A double-blind, placebo-controlled trial. Anesthesia and analgesia, 1990, Volume: 70, Issue:2 Topics: Administration, Oral; Adult; Benzoates; Benzoic Acid; Caffeine; Cerebrovascular Circulation; Double-Blind Method; Female; Headache; Humans; Postpartum Period; Pregnancy; Randomized Controlled Trials as Topic; Spinal Puncture	1990

Other Studies

49 other study(ies) available for benzoic acid and caffeine

Article	Year
Hydrogen-bonding parameter and its significance in quantitative structure--activity studies. Journal of medicinal chemistry, 1977, Volume: 20, Issue:8 Topics: Acetylcholinesterase; Anesthetics; Benzene Derivatives; Benzenesulfonates; Carbamates; Chemical Phenomena; Chemistry; Chemistry, Physical; Hydrogen Bonding; Models, Biological; Models, Chemical; Phenoxyacetates; Solubility; Structure-Activity Relationship	1977
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities. Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4 Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water	2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
[A new solution of simultaneous equations and its application in assay of compound preparations]. Yao xue xue bao = Acta pharmaceutica Sinica, 1990, Volume: 25, Issue:8 Topics: Aminopyrine; Benzoates; Benzoic Acid; Caffeine; Drug Combinations; Injections; Mathematics; Tablets	1990
In vivo percutaneous absorption: a key role for stratum corneum/vehicle partitioning. Archives of dermatological research, 1990, Volume: 282, Issue:8 Topics: Animals; Benzoates; Benzoic Acid; Caffeine; Epidermis; Female; Hydrocortisone; Inulin; Models, Biological; Pharmaceutical Vehicles; Rats; Rats, Inbred Strains; Skin Absorption; Solubility; Thiourea	1990
Cutaneous blood flow and percutaneous absorption: a quantitative analysis using a laser Doppler velocimeter and a blood flow meter. The Journal of investigative dermatology, 1989, Volume: 92, Issue:3 Topics: Animals; Benzoates; Benzoic Acid; Caffeine; Humans; Lasers; Rats; Rats, Nude; Regional Blood Flow; Rheology; Skin; Skin Absorption; Skin Transplantation; Surgical Flaps	1989
The effect of aging on percutaneous absorption in man. Journal of pharmacokinetics and biopharmaceutics, 1989, Volume: 17, Issue:6 Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents; Aspirin; Benzoates; Benzoic Acid; Caffeine; Estradiol; Female; Humans; Hydrocortisone; Injections, Intravenous; Male; Middle Aged; Skin Absorption; Testosterone	1989
The isolated perfused porcine skin flap. III. Percutaneous absorption pharmacokinetics of organophosphates, steroids, benzoic acid, and caffeine. Toxicology and applied pharmacology, 1989, Volume: 97, Issue:2 Topics: Animals; Benzoates; Benzoic Acid; Caffeine; In Vitro Techniques; Insecticides; Models, Biological; Organophosphorus Compounds; Skin Absorption; Steroids; Surgical Flaps; Swine	1989
[Simultaneous determination of multicomponent of Annaka injection using kalmanfiltering spectrophotometry]. Yao xue xue bao = Acta pharmaceutica Sinica, 1988, Volume: 23, Issue:9 Topics: Benzoates; Benzoic Acid; Caffeine; Solutions; Spectrophotometry	1988
[Clouding of consciousness on the withdrawal of caffeine and sodium benzoate]. Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studies & drug dependence, 1988, Volume: 23, Issue:1 Topics: Benzoates; Benzoic Acid; Caffeine; Cognition Disorders; Consciousness Disorders; Humans; Male; Middle Aged; Substance Withdrawal Syndrome	1988
In vivo percutaneous penetration of some organic compounds related to anatomic site in humans: predictive assessment by the stripping method. Journal of pharmaceutical sciences, 1987, Volume: 76, Issue:6 Topics: Adult; Aspirin; Benzoates; Benzoic Acid; Caffeine; Epidermis; Humans; Male; Skin Absorption; Solubility	1987
In vivo relationship between transepidermal water loss and percutaneous penetration of some organic compounds in man: effect of anatomic site. Archives of dermatological research, 1987, Volume: 279, Issue:5 Topics: Absorption; Adult; Aspirin; Benzoates; Benzoic Acid; Body Water; Caffeine; Humans; Male; Permeability; Skin; Tissue Distribution	1987
Vehicle effects on percutaneous absorption: in vivo and in vitro comparisons with human skin. The British journal of dermatology, 1986, Volume: 115, Issue:1 Topics: Adult; Benzoates; Benzoic Acid; Caffeine; Ethylene Glycol; Ethylene Glycols; Humans; In Vitro Techniques; Male; Pharmaceutical Vehicles; Skin Absorption; Solubility; Testosterone; Time Factors	1986
Percutaneous penetration in the hairless dog, weanling pig and grafted athymic nude mouse: evaluation of models for predicting skin penetration in man. The British journal of dermatology, 1984, Volume: 111 Suppl 27 Topics: Animals; Benzoates; Benzoic Acid; Caffeine; DEET; Dogs; Female; Fluocinolone Acetonide; Hexachlorocyclohexane; Humans; Malathion; Mice; Mice, Nude; Parathion; Progesterone; Skin Absorption; Swine; Testosterone	1984
[Nature of the dual caffeine-sodium benzoate effect on the tonic component of the potassium contracture of the myocardium in the frog]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1984, Volume: 70, Issue:2 Topics: Animals; Benzoates; Benzoic Acid; Caffeine; Calcium; Gallopamil; In Vitro Techniques; Ion Channels; Muscle Tonus; Myocardial Contraction; Nifedipine; Potassium; Rana temporaria; Tetracaine	1984
Preparation of caffeine and sodium benzoate injection. American journal of hospital pharmacy, 1983, Volume: 40, Issue:12 Topics: Benzoates; Benzoic Acid; Caffeine; Drug Compounding; Injections	1983
Inadvisability of using caffeine and sodium benzoate in neonates. American journal of hospital pharmacy, 1984, Volume: 41, Issue:4 Topics: Benzoates; Benzoic Acid; Caffeine; Drug Combinations; Humans; Infant, Newborn; Infant, Premature, Diseases	1984
Reversed-phase high-performance liquid chromatographic separation of saccharin, caffeine and benzoic acid using non-linear programming. Journal of chromatography, 1982, Oct-01, Volume: 247, Issue:2 Topics: Benzoates; Benzoic Acid; Beverages; Caffeine; Chromatography, High Pressure Liquid; Models, Chemical; Saccharin; Software	1982
Methods for in vitro percutaneous absorption studies. I. Comparison with in vivo results. Toxicology and applied pharmacology, 1982, Mar-15, Volume: 62, Issue:3 Topics: Animals; Aspirin; Benzoates; Benzoic Acid; Caffeine; Female; In Vitro Techniques; Permeability; Rats; Skin Absorption; Urea	1982
Functional evaluation of anchored skin equivalent cultured in vitro: percutaneous absorption studies and lipid analysis. Pharmaceutical research, 1995, Volume: 12, Issue:3 Topics: Animals; Benzoates; Benzoic Acid; Caffeine; Cells, Cultured; Fibroblasts; Humans; In Vitro Techniques; Keratinocytes; Lipids; Mice; Skin; Skin Absorption; Skin Physiological Phenomena; Sucrose; Time Factors; Urea	1995
A robust procedure for the automated measurement of total serum bilirubin using potassium ferricyanide. Annals of clinical biochemistry, 1993, Volume: 30 ( Pt 2) Topics: Benzoates; Benzoic Acid; Bilirubin; Caffeine; Ferricyanides; Freeze Drying; Hemolysis; Humans; Hyperlipidemias; Indicators and Reagents; Spectrophotometry	1993
Racial differences in the in vivo percutaneous absorption of some organic compounds: a comparison between black, Caucasian and Asian subjects. Archives of dermatological research, 1993, Volume: 284, Issue:8 Topics: Adult; Asian People; Aspirin; Benzoates; Benzoic Acid; Black People; Caffeine; Humans; Skin Absorption; White People	1993
Comparison of capillary zone electrophoresis with high-performance liquid chromatography for the determination of additives in foodstuffs. Journal of chromatography, 1993, Apr-23, Volume: 636, Issue:1 Topics: Aspartame; Benzoates; Benzoic Acid; Beverages; Caffeine; Chromatography, High Pressure Liquid; Electrophoresis; Electrophoresis, Polyacrylamide Gel; Food Additives; Reproducibility of Results; Sweetening Agents	1993
A mathematical model of an aqueous-organic partition-based controlled release system using microporous membranes. Journal of controlled release : official journal of the Controlled Release Society, 1999, Sep-20, Volume: 61, Issue:3 Topics: Benzoic Acid; Caffeine; Delayed-Action Preparations; Kinetics; Mathematical Computing; Membranes, Artificial; Models, Chemical; Nicotine; Organic Chemicals; Solubility; Water	1999
Investigation of some complexes formed in solution by caffeine. II. Benzoic acid and benzoate ion. Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1953, Volume: 42, Issue:3 Topics: Benzoates; Benzoic Acid; Caffeine; Pharmaceutical Solutions; Solutions	1953
Solubilizing action of caffeine on benzoic acid. Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1952, Volume: 41, Issue:1 Topics: Benzoates; Benzoic Acid; Caffeine; Humans	1952
In vitro predictions of skin absorption of caffeine, testosterone, and benzoic acid: a multi-centre comparison study. Regulatory toxicology and pharmacology : RTP, 2004, Volume: 39, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Benzoic Acid; Cadaver; Caffeine; Diffusion Chambers, Culture; Europe; Female; Guideline Adherence; Humans; In Vitro Techniques; Laboratories; Male; Middle Aged; Rats; Reference Standards; Reproducibility of Results; Skin Absorption; Skinfold Thickness; Testosterone	2004
Comparison of bovine udder skin with human and porcine skin in percutaneous permeation experiments. Alternatives to laboratory animals : ATLA, 2006, Volume: 34, Issue:5 Topics: Animals; Benzoic Acid; Caffeine; Cattle; Flufenamic Acid; Humans; In Vitro Techniques; Models, Biological; Permeability; Skin; Skin Absorption; Swine; Testosterone	2006
Influence of membrane-solvent-solute interactions on solute permeation in model membranes. International journal of pharmaceutics, 2007, May-04, Volume: 336, Issue:1 Topics: Administration, Cutaneous; Algorithms; Benzoic Acid; Caffeine; Calorimetry, Differential Scanning; Diffusion; Dimethylpolysiloxanes; Membranes, Artificial; Pharmaceutical Preparations; Pharmaceutical Vehicles; Salicylic Acid; Silicones; Solubility; Solvents; Transition Temperature	2007
Influence of membrane-solvent-solute interactions on solute permeation in skin. International journal of pharmaceutics, 2007, Aug-01, Volume: 340, Issue:1-2 Topics: Analysis of Variance; Benzoic Acid; Caffeine; Cell Membrane Permeability; Diffusion; Diffusion Chambers, Culture; Epidermis; Humans; Membranes, Artificial; Models, Biological; Molecular Structure; Salicylic Acid; Silicones; Skin Absorption; Solubility; Solvents; Time Factors	2007
Defense against dermal exposures is only skin deep: significantly increased penetration through slightly damaged skin. Archives of dermatological research, 2007, Volume: 299, Issue:9 Topics: Administration, Cutaneous; Adult; Benzoic Acid; Caffeine; Dermis; Diffusion; Diffusion Chambers, Culture; Epidermis; Female; Glycine; Glyphosate; Humans; Kinetics; Malathion; Middle Aged; Permeability; Pesticides; Pharmaceutical Preparations; Skin; Skin Absorption; Solubility	2007
Caffeine induces macroautophagy and confers a cytocidal effect on food spoilage yeast in combination with benzoic acid. Autophagy, 2008, Volume: 4, Issue:1 Topics: Autophagy; Benzoic Acid; Caffeine; Cytostatic Agents; Drug Synergism; Food Microbiology; Food Preservation; Fungal Proteins; Humans; Nitrogen; Phosphodiesterase Inhibitors; Saccharomyces cerevisiae; Zygosaccharomyces	2008
The physicochemical parameters of marker compounds and vehicles for use in in vitro percutaneous absorption studies. Alternatives to laboratory animals : ATLA, 2008, Volume: 36, Issue:2 Topics: Animal Testing Alternatives; Animals; Benzoic Acid; Buffers; Caffeine; Clotrimazole; Culture Media; Digoxin; Epidermis; Flufenamic Acid; Germany; Humans; Micelles; Polyethylene Glycols; Skin Absorption	2008
Placental passage of benzoic acid, caffeine, and glyphosate in an ex vivo human perfusion system. Journal of toxicology and environmental health. Part A, 2008, Volume: 71, Issue:15 Topics: Adult; Benzoic Acid; Caffeine; Female; Glycine; Glyphosate; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Models, Biological; Perfusion; Placenta; Pregnancy; Quantitative Structure-Activity Relationship	2008
[Drug permeability through buccal mucosa]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2009, Volume: 38, Issue:2 Topics: Animals; Benzoic Acid; Caffeine; Hydrocortisone; In Vitro Techniques; Mouth Mucosa; Permeability; Swine	2009
Modeling placental transport: correlation of in vitro BeWo cell permeability and ex vivo human placental perfusion. Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:7 Topics: Antipyrine; Benzoic Acid; Caffeine; Cell Line; Cell Membrane Permeability; Female; Glycine; Glyphosate; Humans; Kinetics; Maternal Exposure; Maternal-Fetal Exchange; Models, Biological; Perfusion; Placenta; Pregnancy	2009
The Phenion full-thickness skin model for percutaneous absorption testing. Skin pharmacology and physiology, 2010, Volume: 23, Issue:2 Topics: Animal Testing Alternatives; Animals; Benzoic Acid; Caffeine; Humans; Models, Biological; Nicotine; Permeability; Skin Absorption; Species Specificity; Swine; Testosterone	2010
Improved accuracy in high-temperature conversion elemental analyzer δ18O measurements of nitrogen-rich organics. Rapid communications in mass spectrometry : RCM, 2012, Mar-15, Volume: 26, Issue:5 Topics: Acetanilides; Benzoic Acid; Caffeine; Glycine; Hot Temperature; Mass Spectrometry; Nitrogen; Oxygen Isotopes; Pentaerythritol Tetranitrate; Sucrose	2012
Accurate determination of reference materials and natural isolates by means of quantitative (1)h NMR spectroscopy. Journal of agricultural and food chemistry, 2014, Mar-26, Volume: 62, Issue:12 Topics: Benzoic Acid; Caffeine; Food Analysis; Magnetic Resonance Spectroscopy; Reference Standards; Tyrosine	2014
Skin Concentrations of Topically Applied Substances in Reconstructed Human Epidermis (RHE) Compared with Human Skin Using in vivo Confocal Raman Microscopy. Chimia, 2015, Volume: 69, Issue:3 Topics: Administration, Cutaneous; Benzoic Acid; Caffeine; Camphor; Cinnamates; Diffusion; Epidermis; Humans; Kinetics; Microscopy, Confocal; Models, Biological; Permeability; Salicylic Acid; Spectrum Analysis, Raman	2015
Further development of an in vitro model for studying the penetration of chemicals through compromised skin. Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 38 Topics: 1-Octanol; Administration, Cutaneous; Aminophenols; Animals; Benzoic Acid; Caffeine; In Vitro Techniques; Molecular Weight; Skin; Skin Absorption; Sucrose; Swine; Water	2017
Effect of Esters on the Permeation of Chemicals with Different Polarities through Synthetic Artificial Membranes Using a High-Throughput Diffusion Cell Array. Chemical & pharmaceutical bulletin, 2016, Volume: 64, Issue:11 Topics: Aminopyrine; Benzoic Acid; Caffeine; Cosmetics; Diffusion; Esters; Flurbiprofen; High-Throughput Screening Assays; Membranes, Artificial; Silicones	2016
Diverted medications and new psychoactive substances-A chemical network analysis of discarded injecting paraphernalia in Hungary. The International journal on drug policy, 2017, Volume: 46 Topics: Benzoic Acid; Caffeine; Humans; Hungary; Illicit Drugs; Methadone; Needle Sharing; Opiate Substitution Treatment; Prescription Drug Diversion; Prevalence; Psychotropic Drugs; Substance Abuse, Intravenous; Syringes	2017
Regional variation in percutaneous absorption in the tree frog Litoria caerulea. Environmental toxicology and pharmacology, 2018, Volume: 60 Topics: Animals; Anura; Benzoic Acid; Caffeine; Ibuprofen; Models, Biological; Skin; Skin Absorption; Xenobiotics	2018
Effects of skin region and relative lipophilicity on percutaneous absorption in the toad Rhinella marina. Environmental toxicology and chemistry, 2019, Volume: 38, Issue:2 Topics: Animals; Benzoic Acid; Bufo marinus; Caffeine; Ecosystem; Ibuprofen; In Vitro Techniques; Kinetics; Male; Skin; Skin Absorption; Time Factors; Xenobiotics	2019
Percutaneous absorption between frog species: Variability in skin may influence delivery of therapeutics. Journal of veterinary pharmacology and therapeutics, 2020, Volume: 43, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Anura; Benzoic Acid; Caffeine; Central Nervous System Stimulants; Ibuprofen; Permeability; Skin; Skin Absorption; Species Specificity	2020
Can models of percutaneous absorption based on in vitro data in frogs predict in vivo absorption? PloS one, 2020, Volume: 15, Issue:7 Topics: Animals; Benzoic Acid; Bufo marinus; Caffeine; Cell Membrane Permeability; Diffusion; Ibuprofen; In Vitro Techniques; Male; Models, Biological; Skin; Skin Absorption	2020
Using Prenucleation Aggregation of Caffeine-Benzoic Acid as a Rapid Indication of Co-crystallization from Solutions. Molecular pharmaceutics, 2023, 04-03, Volume: 20, Issue:4 Topics: Acetone; Acetonitriles; Benzoic Acid; Caffeine; Crystallization; Methanol; Solutions; Solvents	2023