benzofurans has been researched along with phenyllithium* in 1 studies
1 other study(ies) available for benzofurans and phenyllithium
Article | Year |
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A general synthetic route to 6,6-substituted-6H-dibenzo[b,d]pyrans from dibenzofuran.
The reaction of dibenzofuran 1, lithium pieces (2.2 equiv), and TMEDA (2.2 equiv) in dry ether under reflux led to a solution of the corresponding C,O-dilithiated intermediate 2 which, upon treatment with different ketones or aldehydes (0.8 equiv) at -78 degrees C, afforded, after hydrolysis and dehydration, 6,6-substituted-6H-dibenzo[b,d]pyrans 3 in good yields. The reaction undergoes reductive ring opening and cyclization, and the intermediate diol 4e was isolated. Topics: Benzofurans; Lithium; Organometallic Compounds; Pyrans | 2006 |