benzofurans and menisdaurilide

benzofurans has been researched along with menisdaurilide* in 4 studies

Other Studies

4 other study(ies) available for benzofurans and menisdaurilide

ArticleYear
Four New Cyclohexylideneacetonitrile Derivatives from the Hypocotyl of Mangrove (Bruguiera gymnorrhiza).
    Molecules (Basel, Switzerland), 2015, Aug-12, Volume: 20, Issue:8

    Four new cyclohexylideneacetonitrile derivatives 1-4, named menisdaurins B-E, as well as three known cyclohexylideneacetonitrile derivatives--menisdaurin (5), coclauril (6), and menisdaurilide (7)--were isolated from the hypocotyl of a mangrove (Bruguiera gymnorrhiza). The structures of the isolates were elucidated on the basis of extensive spectroscopic analysis. Compounds 1-7 showed anti-Hepatitis B virus (HBV) activities, with EC50 values ranging from 5.1 ± 0.2 μg/mL to 87.7 ± 5.8 μg/mL.

    Topics: Acetonitriles; Benzofurans; Cell Line, Tumor; Glycosides; Hepatitis B virus; Humans; Hypocotyl; Plant Extracts; Rhizophoraceae; Wetlands

2015
Diastereoselective synthesis of allosecurinine and viroallosecurinine from menisdaurilide.
    The Journal of organic chemistry, 2008, Oct-03, Volume: 73, Issue:19

    A new and versatile synthetic route to Securinega alkaloids is reported. The first synthesis of allosecurinine has been accomplished in seven steps and 40% yield, starting from (+)-menisdaurilide, using a vinylogous Mannich reaction as the key transformation. Similarly, viroallosecurinine has been synthesized from (-)-menisdaurilide.

    Topics: Alkaloids; Azepines; Benzofurans; Euphorbiaceae; Heterocyclic Compounds, Bridged-Ring; Lactones; Piperidines; Stereoisomerism

2008
Discovery of the apoptosis-inducing activity and high accumulation of the butenolides, menisdaurilide and aquilegiolide in Dicentra spectabilis.
    Planta medica, 2007, Volume: 73, Issue:15

    The occurrence of two butenolides, menisdaurilide and aquilegiolide, in commercial specimens of Dicentra spectabilis is reported for the first time; a rapid and direct isolation protocol is described. The ability of these lactones to induce apoptosis in human tumour cell lines at 10 microM concentration is also described. The high abundance and apoptosis-inducing activity reported here indicates that these constituents play a more significant role than the hormonal action previously attributed to them.

    Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Apoptosis; Benzofurans; Cell Line, Tumor; Fumariaceae; HT29 Cells; Humans; Jurkat Cells; Phytotherapy; Plant Extracts; Plant Leaves; Plant Stems

2007
7,8-Dihydrobenzofuranones from Ouratea reticulata.
    Fitoterapia, 2001, Volume: 72, Issue:6

    Two known 7,8-dihydrobenzofuranones, aquilegiolide (1) and menisdaurilide (2), were isolated from Ouratea reticulata root bark.

    Topics: Benzofurans; Humans; Magnetic Resonance Spectroscopy; Magnoliopsida; Plant Bark; Plant Extracts; Plant Roots

2001