benzofurans and irofulven

benzofurans has been researched along with irofulven* in 1 studies

Reviews

1 review(s) available for benzofurans and irofulven

ArticleYear
Promising new agents for treatment of patients with colorectal cancer.
    Seminars in oncology, 1998, Volume: 25, Issue:5 Suppl 11

    Colorectal cancer continues to be a major problem. There are a number of new agents with promising clinical activity, including the multitargeted antifolate LY 231514 and the thymidylate synthesis inhibitor capecitabine. In addition, other agents have shown promising preclinical activity against the disease: 6-hydroxymethylacylfulvene (HMAF; MGI 114), LY 295501, bizelesin (U-7779; NSC615291), and ONYX-015. Finally, several agents may prevent colorectal cancer through prevention of the formation of colorectal polyps (eg, cyclooxygenase inhibitors).

    Topics: Adenoviridae; Antineoplastic Agents; Benzofurans; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Duocarmycins; Enzyme Inhibitors; Humans; Indoles; Phenylurea Compounds; Sesquiterpenes; Thymidylate Synthase; Tumor Cells, Cultured; Urea

1998