benzofurans has been researched along with hypothemycin* in 2 studies
2 other study(ies) available for benzofurans and hypothemycin
| Article | Year |
|---|---|
An enantioselective total synthesis of (+)-aigialospirol.
A concise and enantioselective total synthesis of (+)-aigialospirol is described here, featuring the first complex natural product synthesis that employs a cyclic ketal-tethered ring-closing metathesis strategy and an unexpected stereoselective epimerization of a benzylic hydroxyl group. The 15-step synthetic sequence illustrates the proof-of-concept that such an approach can be competitive with the classical spiroketal formation in the natural product synthesis. Topics: Benzofurans; Crystallography, X-Ray; Models, Molecular; Molecular Structure; Stereoisomerism; Zearalenone | 2007 |
Ketene acetal and spiroacetal constituents of the marine fungus Aigialus parvus BCC 5311.
Aigialone (1) and aigialospirol (2), two structurally unique compounds, were isolated from the mangrove fungus Aigialus parvus BCC 5311. The structure of the new ketene acetal 1 was elucidated by spectral analysis, and its relative stereochemistry was determined by X-ray crystallography. The stereochemistry of aigialospirol (2), elucidated by NMR spectral analysis, suggested that this compound is possibly derived from hypothemycin (3), a metabolite previously isolated from this same fungus. Topics: Acetals; Ascomycota; Benzofurans; Crystallography, X-Ray; Ethylenes; Ketones; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism; Thailand; Zearalenone | 2004 |