benzofurans has been researched along with dysiherbaine* in 1 studies
1 other study(ies) available for benzofurans and dysiherbaine
Article | Year |
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Design, synthesis, and biological evaluation of a scaffold for iGluR ligands based on the structure of (-)-dysiherbaine.
The design and synthesis of four 2,2-disubstituted dihydrobenzofurans that are structurally related to several glutamate-containing natural products, including (-)-dysiherbaine, is described. Biological evaluation of these analogs shows that one is a KA receptor antagonist and another is an NMDA receptor agonist. Topics: Alanine; Animals; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Excitatory Amino Acid Antagonists; Ligands; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2006 |