benzofurans and beraprost

benzofurans has been researched along with beraprost* in 1 studies

Other Studies

1 other study(ies) available for benzofurans and beraprost

Article	Year
A practical synthesis of chiral tricyclic cyclopenta[b]benzofuran, a key intermediate of Beraprost. Organic & biomolecular chemistry, 2016, Aug-10, Volume: 14, Issue:32 A novel formal synthesis of Beraprost (1) is described. The tricyclic cyclopent[b]benzofuran core is efficiently prepared from (-)-Corey lactone diol in 12 steps with an overall yield of 37.4%. Key features of the strategy include a ring-closing metathesis reaction and aromatization to form the tricyclic cyclopenta[b]benzofuran framework, and selective halogenation/formylation to install the butyrate side-chain. Topics: Benzofurans; Cyclopentanes; Epoprostenol; Molecular Structure	2016

Article

Year

A practical synthesis of chiral tricyclic cyclopenta[b]benzofuran, a key intermediate of Beraprost.

Organic & biomolecular chemistry, 2016, Aug-10, Volume: 14, Issue:32

A novel formal synthesis of Beraprost (1) is described. The tricyclic cyclopent[b]benzofuran core is efficiently prepared from (-)-Corey lactone diol in 12 steps with an overall yield of 37.4%. Key features of the strategy include a ring-closing metathesis reaction and aromatization to form the tricyclic cyclopenta[b]benzofuran framework, and selective halogenation/formylation to install the butyrate side-chain.

Topics: Benzofurans; Cyclopentanes; Epoprostenol; Molecular Structure

2016