benzofurans has been researched along with angucyclinone* in 1 studies
1 other study(ies) available for benzofurans and angucyclinone
| Article | Year |
|---|---|
Isolation, stereochemical study, and racemization of (±)-pratenone A, the first naturally occurring 3-(1-naphthyl)-2-benzofuran-1(3H)-one polyketide from a marine-derived actinobacterium.
(±)-Pratenone A (1), the first representative of natural 3-(1-naphthyl)-2-benzofuran-1(3H)-one polyketides, was isolated from a marine-derived Streptomyces pratensis strain KCB-132 together with three other new analogues (2-4). Its structure was assigned by spectroscopic analysis, and the absolute configurations of the two enantiomers separated by high-performance liquid chromatography were determined by single-crystal X-ray diffraction and electronic circular dichroism calculations. The solvent-induced racemization of 1 and a proposed biogenetic pathway to 1-4 from the co-isolated angucyclinone precursor, as well as their biological activity, are also discussed. Topics: Anthraquinones; Anti-Infective Agents; Aquatic Organisms; Benzofurans; Chromatography, High Pressure Liquid; Circular Dichroism; Crystallography, X-Ray; Hep G2 Cells; HL-60 Cells; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Polyketides; Staphylococcus aureus; Stereoisomerism; Streptomyces | 2020 |