benzofurans has been researched along with amentoflavone* in 1 studies
1 other study(ies) available for benzofurans and amentoflavone
| Article | Year |
|---|---|
Anti-inflammatory phenolics isolated from Juniperus rigida leaves and twigs in lipopolysaccharide-stimulated RAW264.7 macrophage cells.
Inflammation is an essential host defense system particularly in response to infection and injury; however, excessive or undesirable inflammatory responses contribute to acute and chronic human diseases. A high-throughput screening effort searching for anti-inflammatory compounds from medicinal plants deduced that the methanolic extract of Juniperus rigida S. et L. (Cupressaceae) inhibited significantly nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells. Activity-guided fractionation and isolation yielded 13 phenolic compounds, including one new phenylpropanoid glycosides, 3,4-dimethoxycinnamyl 9-O-β-D-glucopyranoside (1). Among the isolated compounds, phenylpropanoid glycosides with p-hydroxy group (2, 4) and massoniaside A (7), (+)-catechin (10), amentoflavone (11) effectively inhibited LPS-induced NO production in RAW264.7 cells. Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Biflavonoids; Catechin; Cell Line; Cell Survival; Cinnamates; Glucosides; Glycosides; Juniperus; Lipopolysaccharides; Macrophage Activation; Macrophages; Methanol; Mice; Nitric Oxide; Phenols; Plant Extracts; Plant Leaves; Solvents | 2012 |