benzofurans and alantolactone

benzofurans has been researched along with alantolactone* in 2 studies

Other Studies

2 other study(ies) available for benzofurans and alantolactone

Article	Year
Contact dermatitis to sesquiterpene lactones in Inula viscosa Aiton. Contact dermatitis, 1987, Volume: 17, Issue:5 Topics: Adult; Benzofurans; Dermatitis, Contact; Female; Flavonoids; Hand Dermatoses; Humans; Inula; Lactones; Patch Tests; Plant Extracts; Sesquiterpenes; Sesquiterpenes, Eudesmane; Skin Diseases, Vesiculobullous	1987
Toxic effect of alantolactone and dihydroalantolactone in in vitro cultures of leukocytes. Chemico-biological interactions, 1976, Volume: 15, Issue:3 Alantolactone, an allergenic sesquiterpene lactone, is toxic to leukocytes in in vitro cultures. Cell (1 X 10(6) cells/ml of culture) stimulation by pokeweed mitogen (PWM) decreases with increasing amounts of terpene. A concentration of 1 mug/ml of culture decreases stimulation by 50%. The reduced terpene, dihydro-11,13-alantolactone (DHA) is also toxic. A concentration of 1.7 mug/ml of culture of DHA brings about a 50% decrease in stimulation. Both compounds affect cell viability as measured by dye exclusion. It is suggested that the toxicity of alantolactone is not due to the presence of the alpha-methylene group conjugated to the carbonyl function of the gamma-lactone system. Topics: Benzofurans; Cells, Cultured; DNA Replication; Kinetics; Lactones; Lectins; Lymphocyte Activation; Lymphocytes; Sesquiterpenes; Sesquiterpenes, Eudesmane; Thymidine	1976

Article

Year

Contact dermatitis to sesquiterpene lactones in Inula viscosa Aiton.

Contact dermatitis, 1987, Volume: 17, Issue:5

Topics: Adult; Benzofurans; Dermatitis, Contact; Female; Flavonoids; Hand Dermatoses; Humans; Inula; Lactones; Patch Tests; Plant Extracts; Sesquiterpenes; Sesquiterpenes, Eudesmane; Skin Diseases, Vesiculobullous

1987

Toxic effect of alantolactone and dihydroalantolactone in in vitro cultures of leukocytes.

Chemico-biological interactions, 1976, Volume: 15, Issue:3

Alantolactone, an allergenic sesquiterpene lactone, is toxic to leukocytes in in vitro cultures. Cell (1 X 10(6) cells/ml of culture) stimulation by pokeweed mitogen (PWM) decreases with increasing amounts of terpene. A concentration of 1 mug/ml of culture decreases stimulation by 50%. The reduced terpene, dihydro-11,13-alantolactone (DHA) is also toxic. A concentration of 1.7 mug/ml of culture of DHA brings about a 50% decrease in stimulation. Both compounds affect cell viability as measured by dye exclusion. It is suggested that the toxicity of alantolactone is not due to the presence of the alpha-methylene group conjugated to the carbonyl function of the gamma-lactone system.

Topics: Benzofurans; Cells, Cultured; DNA Replication; Kinetics; Lactones; Lectins; Lymphocyte Activation; Lymphocytes; Sesquiterpenes; Sesquiterpenes, Eudesmane; Thymidine

1976