benzofurans and 3-4-dichloroaniline

Chloracne, an acneform eruption resulting from poisoning by halogenated aromatic compounds, has been a considerable problem over the last 40 years. The condition is always a symptom of systemic poisoning and should be familiar to all practitioners, particularly dermatologists. It is difficult to treat and can last for long periods without known additional exposure to chloracnegens. Some chloracnegens are capable of causing a variety of systemic signs and symptoms and may be oncogenic. Although there are probably fewer than 4,000 persons with chloracne worldwide, those found with the disorder should be evaluated medically on a regular basis and followed, if possible, throughout their lives.

Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Acne Vulgaris; Agent Orange; Aniline Compounds; Animals; Azo Compounds; Benzofurans; Biphenyl Compounds; Chemical Phenomena; Chemistry; Dibenzofurans, Polychlorinated; Dioxins; Drug Contamination; Halogens; Humans; Hydrocarbons, Chlorinated; Naphthalenes; Neoplasms; Polychlorinated Dibenzodioxins