benzofuran has been researched along with benzofurans in 358 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (5.31) | 18.7374 |
| 1990's | 6 (1.68) | 18.2507 |
| 2000's | 88 (24.58) | 29.6817 |
| 2010's | 197 (55.03) | 24.3611 |
| 2020's | 48 (13.41) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, SK; Lee, SH; Yoo, SE | 1 |
| Dukhanin, AS; Galenko-Iaroshevskiĭ, PA; Khankoeva, AI | 1 |
| Djuric, SW; Hulme, C; McGarry, DG; Miller, BE; Moriarty, KJ; Regan, JR; Souness, JE; Sweeney, DM; Travis, JJ; Volz, FA | 1 |
| Colquhoun, IJ; Garcia-Conesa, MT; Kroon, PA; Mellon, FA; Ralph, J; Saulnier, L; Thibault, JF; Williamson, G | 1 |
| Knoll, B; Knoll, J; Miklya, I; Ohde, H; Yoneda, F | 1 |
| Kim, NJ; Kim, SK; Lee, DW; Lee, SH; Yoo, SE | 1 |
| Ando, T; Ishida, T; Knoll, J; Oka, T; Watanabe, M; Yasusa, T; Yoneda, F | 1 |
| Nakai, S; Yoneda, F | 1 |
| Carson, MW; Danishefsky, SJ; Frontier, AJ; Inoue, M | 1 |
| Balasubramanian, S | 1 |
| Huang, SJ; Sha, CK; Zhan, ZP | 1 |
| Bell, PD; Peti-Peterdi, J; Warnock, DG | 1 |
| Chang, CJ; Deng, Y; Lee, GH; Nocera, DG; Peng, SM; Yeh, CY | 1 |
| Fathi, R; Liao, Y; Reitman, M; Yang, Z; Zhang, Y | 1 |
| Bailey, NJ; Borgeaud, N; Connelly, JC; Connor, SC; Gavaghan, CL; Holmes, E; Monte, S; Nicholson, JK; Troke, J | 1 |
| Schneider, B | 1 |
| BEKAERT, J; BROEKHUYSEN, J; DELTOUR, G | 2 |
| CHARLIER, R | 1 |
| PAN, F; WIESE, GA | 1 |
| BUU-HOI, NP; SUU, VT; XUONG, ND | 1 |
| MOCK, A; REISCH, J; SCHULTE, KE | 1 |
| BINON, F; CHARLIER, R; DELTOUR, G; TONDEUR, R | 1 |
| BINON, F; CHARLIER, R; DELTOUR, G; HENAUX, F; HOSSLET, A; MARCOVICI, J | 1 |
| BINON, F; CHARLIER, R; DELTOUR, G; DERAY, E; GOLDENBERG, C; HENAUX, F; SION, R; TONDEUR, R | 1 |
| BINON, F; CHARLIER, R; DELTOUR, G | 2 |
| PERMUTTI, B; TODESCO, S | 1 |
| DEMARCHI, F; MISITI, D; ROSNATI, V | 1 |
| CHIAVARELLI, S; CIRIACI, E; GATTA, F; LANDIVITTORY, R | 1 |
| BROEKHUYSEN, J; DELTOUR, G; LISSITZKY, S | 1 |
| ANDREOLI, M; DELUCA, F | 1 |
| BETZ, E; HENSEL, H; SCHMAHL, FW | 1 |
| BORGES, AD; MALTEZ, JS | 1 |
| Ando, K; Kohno, S; Kunitomo, J; Ohishi, Y; Ohta, S; Tsuji, E; Yamashita, M | 1 |
| Ghorai, BK; Herndon, JW; Jiang, D | 1 |
| Agatsuma, T; Furukawa, H; Hayakawa, I; Naruto, S; Shioya, R; Sugano, Y | 1 |
| Choi, HD; Kang, BW; Seo, PJ; Son, BW | 1 |
| de la Fuente, JR; Gil, RR; Palermo, J; Sosa, VE; Uriburu, ML | 1 |
| Fukai, T; Hano, Y; Oku, Y; Terada, S | 1 |
| Baroni, D; Brambilla, G; Carrozzino, R; Mereto, E; Robbiano, L | 1 |
| Altenbach, R; Black, L; Cowart, M; Faghih, R; Hancock, AA; Zhao, C | 1 |
| Bae, K; Cai, XF; Dat, NT; Kim, YH; Shen, Q; Van Kiem, P | 1 |
| Brun, R; Lemière, G; Pieters, L; Schmidt, TJ; Van Dyck, S; Van Miert, S; Vlietinck, A | 1 |
| Bennani, YL; Cowart, MD; Curtis, MP; Esbenshade, TA; Faghih, R; Gfesser, GA; Hancock, AA | 1 |
| Bennani, Y; Cowart, M; Curtis, M; Drescher, K; Esbenshade, TA; Faghih, R; Fox, GB; Gfesser, G; Hancock, AA; Krueger, K; Marsh, K; Miller, TR; Pan, JB; Sun, M; Wetter, J; Zhao, C | 1 |
| Gray, AI; Rahman, MM | 1 |
| Gopal, M; Khan, IA; Kulkarni, MV; Shahabuddin, MS; Sun, CM | 1 |
| Saberi, MR; Shah, K; Simons, C | 1 |
| Collins, E; Du, X; Geck, M; Hotchandani, R; Levin, JI; Lovering, FE; Rush, TS; Skotnicki, J; Wu, J; Xu, ZB | 1 |
| Mataka, S; Thiemann, T; Watanabe, M | 1 |
| Brossi, A; Greig, NH; Holloway, HW; Luo, W; Parrish, D; Yu, QS | 1 |
| Caminati, W; Favero, LB; Giuliano, BM; Maris, A; Melandri, S; Ottaviani, P; Velino, B | 1 |
| Abe, K; Nakao, K; Nakayama, M; Ogawa, H; Saito, Y; Sakamoto, T; Shono, M; Suzuki, S; Yamamuro, M; Yasue, H; Yoshimura, M | 1 |
| Ahmad, G; Gupta, P; Maurya, R; Mishra, PK; Srivastava, AK; Tamrakar, AK; Tiwari, P; Yadav, PP | 1 |
| Abdel-Gawad, H; Dawood, KM; Ellithey, M; Mohamed, HA; Rageb, EA | 1 |
| Kara, H; Karatas, F; Koca, M; Servi, S | 1 |
| Benkli, K; Demirayak, S; Gündoğdu-Karaburun, N; Tunali, Y; Uçucu, U | 1 |
| Haratake, M; Kawai, T; Kawashima, H; Kung, HF; Kung, MP; Mori, H; Nakayama, M; Nonaka, A; Ono, M; Saji, H | 1 |
| Lazo, JS; Nunes, R; Queiroz de Oliveira, PE; Skoko, JJ; Vogt, A; Wipf, P | 1 |
| Bhatia, K; Cowart, M; Esbenshade, TA; Esser, R; Gfesser, GA; Hancock, AA; Krueger, K; Miller, TR; Sun, M; Witte, D | 1 |
| Ballesteros, A; Barluenga, J; González, JM; Merino, I; Vázquez-Villa, H | 1 |
| Boeckler, F; Gmeiner, P; Hübner, H; Schlotter, K | 1 |
| Collins, N; Fardis, M; Kirschberg, T; Mertzman, M; Polniaszek, R; Thomas, W; Watkins, WJ | 1 |
| Fennie, MW; Kozlowski, MC; Waters, SP | 1 |
| Lorberboym, M; Schachter, P | 1 |
| Baranowski, JL; Brioni, JD; Browman, KE; Buckley, MJ; Cowart, M; Deng, X; Diaz, GJ; Diehl, MS; Esbenshade, TA; Faghih, R; Fox, GB; Gagne, GD; Gfesser, GA; Hancock, AA; Komater, VA; Krueger, KM; Marsh, KC; Milicic, I; Miller, TR; Molesky, AL; Pan, L; Roberts, EM; Wetter, JM; Witte, DG; Zhou, D | 1 |
| de Koning, CB; Fernandes, MA; Govender, S; Pelly, SC; Schmalz, HG | 1 |
| Amani, A; Nematollahi, D; Tammari, E | 1 |
| Bratton, L; Cheng, XM; Erasga, N; Filzen, GF; Geyer, A; Lee, C; Lu, G; Pulaski, J; Sorenson, RJ; Trivedi, BK; Unangst, PC; Xu, X | 1 |
| Al-Amoudi, M; Al-Dirbashi, OY; Al-Qahtani, K; Rashed, MS; Santa, T | 1 |
| Canuti, E; Castro-Jiménez, J; Christoph, EH; Eisenreich, SJ; Hanke, G; Huber, T; Mariani, G; Mueller, A; Skejo, H; Umlauf, G; Vives, I; Wollgast, J | 1 |
| Bower, KS; Dougherty, DA; Kedrowski, SM | 1 |
| Fukai, T; Nomura, T; Shi, YQ | 1 |
| Cai, H; Edwards, JP; Gu, Y; Jiang, W; Karlsson, L; Meduna, SP; Pio, BA; Sun, S; Thurmond, RL; Wei, J | 1 |
| El Sous, M; Holloway, G; Khoo, ML; Owen, D; Rizzacasa, MA; Scammells, PJ | 1 |
| Biradar, SS; Jadhav, VB; Kulkarni, MV; Rasal, VP; Vinay, MD | 1 |
| Babini, E; Camerino, DC; Carbonara, G; Fracchiolla, G; Laghezza, A; Liantonio, A; Loiodice, F; Picollo, A; Pusch, M; Tortorella, P; Zifarelli, G | 1 |
| Anand, R; Christ, DD; Covington, MB; Duan, JJ; Liu, RQ; Lu, Z; Newton, RC; Ott, GR; Qian, M; Trzaskos, J; Vaddi, K | 1 |
| Arya, P; Babu, N; Daniel, K; Enright, GD; Leek, DM; Lefrance, M; Nandy, JP; Rakic, B; Sabourin, LA; Sarma, BV | 1 |
| Black, LA; Brioni, J; Browman, KE; Cowart, MD; Diaz, GJ; Esbenshade, TA; Fox, GB; Liu, H; Marsh, KC; Miller, TR; Wetter, J | 1 |
| Kidd, S; Marona-Lewicka, D; Monte, A; Nichols, DE; Prescher, JA; Schultz, DM | 1 |
| Guo, DA; Han, J; Kang, J; Sun, JH; Wang, BR; Ye, M; Zhou, L | 1 |
| Hobson, SJ; Marquez, R; Parkin, A | 1 |
| Ahmat, M; Huang, X; Yang, XW | 1 |
| Bard, J; Cheng, H; Chopra, R; Chunduru, SK; Howe, AY; Johann, S; Krishnamurthy, G; Mansour, T; Mullen, S; O'Connell, J; Young, DC | 1 |
| Hess, M; Lehr, M; Schulze Elfringhoff, A | 1 |
| Gao, K; Jiang, HX; Liu, Q | 1 |
| Gerstenberger, BS; Konopelski, JP; Lin, J; Stessman, NY | 1 |
| Burch, JD; Eidamshaus, C | 1 |
| Boonsombat, J; France, S; Leverett, CA; Padwa, A | 1 |
| Byun, JH; Kim, DJ; Kim, H; Kim, Y; Lee, WK; Mook-Jung, I; Yoo, KH | 1 |
| Echeverría, J; Rezende, MC; Urzúa, A; Wilkens, M | 1 |
| CAGNIANT, P; CHATELUS, G | 1 |
| Hashizume, D; Kakusawa, N; Kobayashi, N; Kurita, J; Liu, CY; Matsumoto, Y; Muranaka, A; Okuda, M; Tsuchiya, T; Uchiyama, M; Yasuike, S; Yoshida, K | 1 |
| dos Santos, AR; Falcão, CA; Férézou, JP; Kaiser, CR; Muzitano, MF; Rossi-Bergmann, B | 1 |
| Lautens, M; Tseng, NW | 1 |
| Adams, TE; El Sous, M; Hawkins, BC; Hirner, S; Holloway, G; Khoo, ML; Owen, DJ; Rizzacasa, MA; Savage, GP; Scammells, PJ | 1 |
| Abegaz, BM; Amadou, D; Bezabih, M; Donfack, JH; Fotso, GW; Fozing, CD; Kapche, GD; Moundipa, PF; Ngadjui, BT; Tchana, AN | 1 |
| Aoki, Y; Asoh, K; Ebiike, H; Fukami, TA; Hyoudoh, I; Ishii, N; Kawasaki, K; Kohchi, M; Kondoh, O; Masubuchi, M; Ohtsuka, T; Sakaitani, M; Shimma, N; Shiratori, Y; Tsukaguchi, T | 1 |
| Ao-Ieong, G; Cammack, N; Giannetti, AM; Hang, JQ; Harris, SF; Klumpp, K; Le Pogam, S; Leveque, V; McCown, MF; Nájera, I; Rajyaguru, S; Talamás, F; Whittington, HJ; Wong, A; Yang, Y | 1 |
| Ford, PC; Iretskii, AV; Johnson, CL; Lewis, RS; Macala, GS; Matson, TD | 1 |
| Abdel-Aziz, HA; Dawood, KM; Mekawey, AA | 1 |
| Magauer, T; Martin, HJ; Mulzer, J | 1 |
| Collette, P; de Lera, AR; Gronemeyer, H; Khanwalkar, H; Mauvais, P; Santín, EP; Voegel, J | 1 |
| Desai, UR; Hindle, M; Liang, A; Sidhu, PP; Verghese, J; Zhou, Q | 1 |
| de Fátima, A; Deavours, BE; Dixon, RA; Farag, MA; Naoumkina, M; Sumner, LW | 1 |
| Jiang, H; Li, W; Liu, G; Shen, J; Tang, Y | 1 |
| Arisawa, A; Fujita, N; Ikenaga, H; Kabumoto, H; Misawa, N; Shindo, K; Sumisa, F | 1 |
| Ando, M; Fukami, T; Gomori, A; Haga, Y; Ishihara, A; Ishii, Y; Ishikawa, M; Iwaasa, H; Kanatani, A; Kanesaka, M; Kitazawa, H; Mitobe, Y; Murai, T; Nonoshita, K; Oda, Z; Ohe, T; Sakamoto, T; Shibata, T; Suga, T; Takahashi, H; Takahashi, T | 1 |
| Bakunov, SA; Bakunova, SM; Barszcz, T; Bridges, AS; Brun, R; Tidwell, RR; Wenzler, T; Werbovetz, KA | 1 |
| Ono, M | 1 |
| Andree, TH; Dos Santos, O; Ellingboe, J; Evrard, DA; Harrison, BL; Hornby, GA; Scerni, R; Schechter, LE; Smith, DL; Venkatesan, AM | 1 |
| Deiters, A; Lusic, H; Uprety, R | 1 |
| Chen, RY; Gong, T; Liu, P; Wang, DX; Yang, Y; Yu, DQ | 1 |
| Ding, C; Hu, W; Li, F; Tu, S; Yao, Q; Zhang, A | 1 |
| Arzel, L; Escudier, JM; Lebreton, J; Len, C | 1 |
| Abd El-All, AS; El-Diwani, HI; Galal, SA; Hegab, KH; Magd-El-Din, AA; Youssef, NS | 1 |
| Chen, RY; Gong, T; Liu, C; Tan, YX; Yu, DQ | 1 |
| Babic, S; Calvin, W; Cui, J; Luedtke, RR; Mach, RH; Taylor, M; Vangveravong, S; Xu, J | 1 |
| Aiyar, N; Burns-Kurtis, CL; Davenport, EA; Erhardt, JA; Kallal, LA; Marino, JP; Morrow, DM; Senadhi, S; Thalji, RK | 1 |
| Agrawal, YK; Manna, K | 1 |
| Manabe, K; Wang, JR | 1 |
| Cheng, Y; Kagawa, S; Kimura, H; Nishii, R; Ono, M; Saji, H | 1 |
| Braun, M; Fischer, A; Frank, W; Grittner, D; Lachenicht, S; Lemoine, H; Rood, A; Schmidt, C; Winkler, M; Wrobel, T | 1 |
| Cacchi, S; Fabrizi, G; Goggiamani, A | 1 |
| Chun, YS; Kim, JH; Lee, SG; Ryu, KY; Shin, H | 1 |
| Hajra, A; Kundu, D; Majee, A; Samim, M | 1 |
| Amann, R; Beifuss, U; Conrad, J; Greiner, G; Leutbecher, H; Stolz, A | 1 |
| Fernandes, PA; Moorthy, NS; Ramos, MJ; Sousa, SF | 1 |
| Rosenberg, ML; Sen Gupta, N; Tilset, M; Vlašaná, K; Wragg, D | 1 |
| Fan, R; Ye, Y | 1 |
| Li, C; Li, P; Wang, L; Zhang, Y | 1 |
| Hashmi, AS; Rominger, F; Yang, W | 1 |
| Cahard, D; Ma, JA; Meng, W; Nie, J; Zhang, FG; Zhu, CL | 1 |
| Cui, M; Kimura, H; Liu, B; Ono, M; Saji, H | 1 |
| Allan, AC; Billinton, A; Brown, SH; Chowdhury, A; Eatherton, AJ; Fieldhouse, C; Giblin, GM; Goldsmith, P; Hall, A; Hurst, DN; Naylor, A; Rawlings, DA; Scoccitti, T; Sime, M; Theobald, PJ | 1 |
| Fennie, MW; Kozlowski, MC; Lowell, AN | 1 |
| Antczak, C; Bassit, B; de Stanchina, E; Djaballah, H; Frattini, MG; Li, Y; Scheinberg, DA; Shum, D | 1 |
| Bao, X; Chen, P; Ding, M; Fan, CA; Han, XJ; Li, J; Tu, YQ; Zhang, GB; Zhang, LF | 1 |
| Bollig, R; Götz, C; Gratz, A; Jose, J; Kuckländer, U | 1 |
| Kitanaka, S; Matsuzaki, K; Takamatsu, S; Yang, ZG | 1 |
| Balzarini, J; Baraldi, PG; Bermejo, J; Brancale, A; Carrion, MD; Chen, L; Cruz-Lopez, O; Estévez, F; Estévez, S; Hamel, E; Kim, JG; Kimatrai Salvador, M; Lopez-Cara, C; Ricci, A; Romagnoli, R | 1 |
| Ji, ZQ; Lu, LN; Luan, JY; Wei, SP; Wu, WJ | 1 |
| Kong, X; Li, C; Liu, X; Shi, Z; Tu, L; Wang, Y; Zeng, Q; Zhang, H; Zhang, Y | 1 |
| Cromer, BA; Dixon, CL; Lynagh, T; Lynch, JW; Webb, TI | 1 |
| Liu, G; Pu, S; Wu, J; Ye, S | 1 |
| Arimitsu, K; Hasegawa, K; Iwasaki, H; Kakimoto, Y; Kawasaki, I; Komai, T; Kosuga, Y; Kurume, A; Miyoshi, T; Nakanishi, A; Nomura, S; Ohta, S; Ozeki, M; Yamaguchi, S; Yamashita, M | 1 |
| Güney, O; Kandaz, M; Salih, B; Yarasir, MN | 1 |
| Liu, ZQ; Zhao, C | 1 |
| Harini, ST; Kumar, HV; Naik, N; Rangaswamy, J | 1 |
| Li, H; Li, X; Ma, X; Wang, P; Yang, M; Zhai, F | 1 |
| Kumar, S; Namkung, W; Sharma, PK; Verkman, AS | 1 |
| Albini, A; Fagnoni, M; Protti, S | 1 |
| Ananthan, S; Arasappan, A; Bennett, F; Chase, R; Clark, JL; Curry, S; Fowler, AT; Geng, F; George Njoroge, F; Girijavallabhan, V; Huang, HC; Huang, Y; Huelgas, R; Kezar, HS; Kwong, CD; Li, C; MacCoss, M; Maddry, JA; Piwinski, JJ; Reynolds, RC; Rossman, R; Roychowdhury, A; Secrist, JA; Shih, NY; Tong, X | 1 |
| Allen, CC; Boyd, DR; Brannigan, IN; Evans, TA; Haughey, SA; Malone, JF; McIntyre, PB; McMurray, BT; Sharma, ND; Stevenson, PJ | 1 |
| Brorström-Lundén, E; Haglund, P; Kylin, H; Olofsson, U | 1 |
| Abdayem, R; Barret, R; Colomb, E; Dubois, J; Guillaume, J; Haftek, M; Lomberget, T; Nachtergaele, L; Nguyen, TT; Thoret, S; Tran, NC | 1 |
| Charalampou, D; Hadjiarapoglou, L; Hadjikakou, SK; Kalpogiannaki, D; Kourkoumelis, N; Kubicki, M; Lazarou, K; Manos, MJ; Paizanos, K; Spanopoulou, A; Tasiopoulos, AJ | 1 |
| Dong, X; Xiao, T; Zhou, L | 1 |
| Blevitt, JM; Booker, JN; Chrovian, CC; Crawford, S; de Leon, AR; Deng, X; Eccles, W; Fourie, AM; Grice, CA; Herman, K; Karlsson, L; Kearney, AM; Lee-Dutra, A; Liang, J; Luna, R; Pippel, D; Rao, N; Riley, JP; Santillán, A; Savall, B; Tanis, VM; Xue, X; Young, AL | 1 |
| Guan, X; Guo, X; Hu, W; Jiang, J; Liu, S; Lv, F; Ma, X; Ren, B; Wu, X | 1 |
| Davies, L; Marais, R; Ménard, D; Niculescu-Duvaz, D; Niculescu-Duvaz, I; Pons, JF; Springer, CJ; Suijkerbuijk, BM; Whittaker, S; Zambon, A | 1 |
| Altomare, C; Barletta, M; Carotti, A; Catto, M; Cellamare, S; Introcaso, A; Mendez-Alvarez, E; Nicolotti, O; Pisani, L; Soto-Otero, R; Stefanachi, A | 1 |
| Bethell, RC; Cordingley, MG; DeRoy, P; Duan, J; Duplessis, M; Edwards, PJ; Faucher, AM; Halmos, T; James, CA; Kuhn, C; Lacoste, JÉ; Lamorte, L; LaPlante, SR; Malenfant, E; Minville, J; Morency, L; Morin, S; Rajotte, D; Salois, P; Simoneau, B; Sturino, CF; Tremblay, M; Tremblay, S | 1 |
| Daicho, S; Nibu, Y; Sasaki, H; Yamada, Y | 1 |
| Bethell, R; Cordingley, M; DeRoy, P; Duan, J; Duplessis, M; Edwards, PJ; Halmos, T; James, CA; Lamorte, L; Minville, J; Morency, L; Morin, S; Pelletier, A; Rajotte, D; Salois, P; Simoneau, B; Sturino, CF; Tremblay, M; Tremblay, S | 1 |
| Chen, J; Ding, J; Liu, M; Wang, Q; Wang, X; Wu, H; Xu, L | 1 |
| Abdel Aziz, MH; Desai, UR; Mehta, AY; Sarkar, A; Sidhu, PS; Zhou, Q | 1 |
| Burstein, ES; Gustavsson, AL; Hansen, LK; Ma, JN; Olsson, R; Sundén, H | 1 |
| Gao, M; Miller, KD; Wang, M; Zheng, QH | 1 |
| Chen, W; Deng, XY; Li, Y; Wan, WC; Wang, XQ; Yang, LJ; Yang, XD; Zhang, HB | 1 |
| Deng, WQ; He, BF; Huang, NY; Li, XY; Luo, HJ | 1 |
| Davis, TZ; Green, BT; Hall, JO; Lee, ST; Stegelmeier, BL | 1 |
| Rawal, VH; Türkmen, YE | 1 |
| Dubois, J; Grellier, P; Thévenin, M; Thoret, S | 1 |
| Akimoto, I; Motegi, K; Nishizono, N; Oda, K; Wada, K; Yamaguchi, Y; Yoshimura, T | 1 |
| Esrafili, MD; Fereyduni, E; Shabrendi, H; Vessally, E | 1 |
| Balintová, J; Fojta, M; Havran, L; Hocek, M; Plucnara, M; Pohl, R; Vidláková, P | 1 |
| Katsumata, H; Manabe, K; Yamaguchi, M | 1 |
| Kantevari, S; Sridevi, JP; Sriram, D; Yempala, T; Yogeeswari, P | 1 |
| Bhatia, G; Modukuri, RK; Rao, KB; Sashidhara, KV; Sonkar, R | 1 |
| Karthiga, A; Reddy, KK; Selvaraj, C; Singh, SK; Suryanarayanan, V; Tripathi, SK | 1 |
| Asano, S; Igarashi, J; Isobe, Y; Koga, E; Koike, N; Komiya, M; Nakatani, S | 1 |
| Bazin, MA; Bodero, L; Marchand, P; Roussakis, C; Rousseau, B; Tomasoni, C | 1 |
| Bandholtz, S; Goebel, M; Gust, R; Herbst, L; Kintscher, U | 1 |
| Li, M; Li, Z; Song, J; Tang, C; Wu, F; Xiao, H; Xie, Y; Zhao, J; Zheng, P | 1 |
| Kamal, A; Nayak, VL; Nimbarte, VD; Prasad, B; Reddy, CS; Reddy, NV; Reddy, VS; Srinivasulu, V; Vishnuvardhan, MV | 1 |
| Kong, LY; Luo, JG; Pan, K; Shan, SM; Zhang, W; Zhou, ZB | 1 |
| Ma, S; Yuan, W | 1 |
| Banwell, MG; Lan, P; Willis, AC | 1 |
| Ichii, Y; Ito, Y; Kakiuchi, M; Miyata, O; Shono, H; Ueda, M | 1 |
| Feng, J; Feng, X; Kang, T; Lin, L; Liu, X; Wang, Z; Yao, Q | 1 |
| Ihalainen, JA; Lehtivuori, H; Nissinen, M; Salorinne, K; Tero, TR | 1 |
| Choi, SJ; Jin, G; Nho, JH; Oh, SY; Ryu, CK | 1 |
| Geng, L; Huang, W; Li, S; Lu, S; Shen, Q; Zhang, J | 1 |
| Chavagnan, T; de Gramont, A; Désaubry, L; Faivre, S; Raymond, E; Ribeiro, N; Salomé, C; Serova, M; Thuaud, F | 1 |
| Montoya, LA; Pluth, MD | 1 |
| Camerino, DC; Gradogna, A; Imbrici, P; Liantonio, A; Pusch, M | 1 |
| Antoniou, A; Bantzi, M; Chatzopoulou, M; Giannis, A; Haroutounian, SA; Koulocheri, SD; Pitsinos, EN | 1 |
| Liu, ZQ; Xi, GL | 1 |
| Ai, N; Chong, CM; Hoi, PM; Hou, T; Lee, SM; Li, CW; Li, S; Liang, W; Pan, P; Shen, M; Yu, H; Zhang, LQ; Zhou, ZY | 1 |
| George, JT; Sabale, PM; Srivatsan, SG | 1 |
| Blum, TR; Nordeen, SA; Yoon, TP; Zhu, Y | 1 |
| Iikuni, S; Kimura, H; Matsumura, K; Ono, M; Saji, H; Watanabe, H; Yoshimura, M | 1 |
| Dodda, RP; Haque, R; Jadiya, P; Kumar, M; Kumar, V; Modukuri, RK; Nazir, A; Sashidhara, KV; Siddiqi, MI; Sridhar, B | 1 |
| Agasti, S; Maiti, D; Naveen, T; Sharma, U | 1 |
| Alcázar, V; Fuentes de Arriba, AL; Herrero, AG; Monleón, LM; Morán, JR; Rubio, OH; Sanz, F; Simón Rubio, L | 1 |
| Davies, HM; Gu, Z; Guptill, DM; Lu, P; Mailyan, A; Wang, H; Zakarian, A | 1 |
| Babu, KS; Chuppala, A; Jeankumar, VU; Reddy, KI; Renuka, J; Sree, KS; Sridevi, JP; Srihari, K; Sriram, D; Yogeeswari, P | 1 |
| Harmalkar, DS; Jang, K; Lee, K; Naik, R; Xu, X | 1 |
| Ahn, HC; Chae, HS; Chin, YW; Kang, M; Kim, J; Kim, YM; Ryu, KH; Yoo, H; Yoon, KD | 1 |
| Ito, T; Kanamori, T; Kuwasako, K; Masaki, Y; Muto, Y; Ohkubo, A; Ohzeki, H; Seio, K; Sekine, M; Shirouzu, M; Takahashi, M; Tsuda, K | 1 |
| Kavanagh, P; Maurer, HH; Meyer, MR; Welter, J | 1 |
| Khanam, H | 1 |
| Cieslak, M; Kazmierczak-Baranska, J; Kossakowski, J; Krawiecka, M; Krolewska, K; Kuran, B; Nawrot, B | 1 |
| Batel, A; Braunbeck, T; Kais, B; Stengel, D | 1 |
| Liu, X; Sun, X; Wang, M; Zhou, L; Zhu, J | 1 |
| Radadiya, A; Shah, A | 1 |
| Don, MJ; Hsieh, JF; Huang, KF; Li, WT; Liao, JH; Lin, WJ; Shen, CC; Shiao, YJ | 1 |
| Balcazar, DE; Bellera, CL; Carrillo, C; Casassa, AF; Fraccaroli, L; Labriola, CA; Romano, PS; Sbaraglini, ML; Talevi, A; Vanrell, MC | 1 |
| Bhadbhade, M; Black, DS; Griffith, R; Kandemir, H; Kumar, N; Lewis, PJ; Ma, C; Mielczarek, M; Thomas, RV; Yang, X | 1 |
| Chen, W; Ma, X; Wang, H; Wu, F; Yi, X | 1 |
| Veeraiah, A | 1 |
| Guo, HF; Jin, J; Ju, DH; Li, ZR; Liu, MJ; Liu, ZY; Xue, ST | 1 |
| Ben Ammar, H; Ben Hassine, B; Doucet, H; Hfaiedh, A; Soulé, JF; Yuan, K | 1 |
| Asadi, J; Gharaei, R; Rostami-Charati, F; Soleimani, A | 1 |
| Cho, J; Choi, M; Han, SB; Jo, H; Jung, JK; Kim, Y; Kwak, JH; Lee, H; Lee, J; Lee, K; Park, HJ; Sateesh Kumar, A; Yun, J | 1 |
| Dighe, SN; Nevagi, RJ | 1 |
| Crooks, PA; Penthala, NR; Thakkar, S | 1 |
| Covaci, A; Erratico, C; Kinyua, J; Lai, FY; Mueller, JF; van Nuijs, AL | 1 |
| de Vries, P; Foekema, EM; Kotterman, M; Murk, AJ | 1 |
| Chen, JJ; Geng, CA; Huang, XY; Liang, WJ; Ma, YB; Xu, HB; Zhang, XM | 1 |
| Alinezhad, H; Emami, S; Foroumadi, A; Mahdavi, M; Mohammadi Ziarani, G; Moradi, A; Mostofi, M; Nadri, H; Shafiee, A | 1 |
| Das, AK; Fukui, H; Itou, T; Karmakar, S; Kashiwada, Y; Mizuguchi, H; Mukherjee, PK; Nemoto, H; Shill, MC | 1 |
| Eda, S; Hamura, T | 1 |
| Aviyente, V; Bozkurt, E; Gilmour, R; Holland, MC; Holmes, AB; Hooper, JF; Houk, KN; James, NC; White, JM | 1 |
| Fujiwara, N; Hasegawa, F; Inoue, Y; Isobe, M; Isobe, Y; Tobe, M; Tsuboi, K | 1 |
| More, AA; Ramana, CV | 1 |
| Gupta, P; Manna, SK; Mokhamatam, RB; Raviprakash, N; Zaidi, AH | 1 |
| Crump, D; Farmahin, R; Giesy, JP; Kennedy, SW; Letcher, RJ; Su, G | 1 |
| Buchet, R; Lemaire, M; Marquès, S; Mebarek, S; Popowycz, F | 1 |
| Hosono, S; Motegi, M; Oh, K; Ohtsuka, N; Pan, Y; Qian, G; Wu, S; Yonemochi, S; Zhang, J; Zhang, L; Zhou, J | 1 |
| Gangwar, MK; Ghosh, P; Kalita, ACh; Kumar, A; Mhatre, D; Prakasham, AP | 1 |
| Chao, H; Chen, LM; Liang, JX; Liu, YY; Xie, YY; Xu, L | 1 |
| Delogu, GL; Era, B; Fais, A; Fanti, M; Kumar, A; Matos, MJ; Medda, R; Pieroni, E; Pintus, F | 1 |
| Chen, F; Di, H; Lan, L; Li, J; Lu, Y; Sheng, C; Wang, X; Wang, Y; Wei, H; Xiao, Q; Xu, Y; Zhang, L; Zhu, J | 1 |
| Mo, XF; Sun, HP; Wang, JL; Wei, JL; Xie, YY; Yang, YR; You, QD; Yuan, ZW; Zhang, C | 1 |
| Bokach, NA; Boyarskiy, VP; Ryabukhin, DS; Vasilyev, AV | 1 |
| Kamal, A; Lakshma Nayak, V; Nagesh, N; Subba Reddy, NV; Vishnuvardhan, MV | 1 |
| Abumansour, H; Gravell, S; Irfan, J; Kashtl, G; Khot, M; Patterson, LH; Pors, K; Sellars, JD; Skipsey, M; Sutton, CW | 1 |
| Hayashi, S; Inui, Y; Koyama, N; Ohra, T; Shirasaki, M; Tokumaru, K; Tokunaga, N; Tsukamoto, T; Wakabayashi, T; Yamada, R | 1 |
| Kimura, H; Ono, M; Saji, H; Watanabe, H; Yoshimura, M | 1 |
| Buck, S; Collett, MG; Davis, TZ; Evans, TJ; Green, BT; Grum, DS; Lee, ST; Pfister, JA; Stegelmeier, BL | 1 |
| Cai, T; Li, J; Ming, P; Ning, Y; Tang, F; Tao, T; Xie, S | 1 |
| Guo, C; Guo, M; Liang, Z; Su, X; Tian, Y; Xu, H | 1 |
| Hu, CY; Lin, YP; Mao, ZW; Rao, GX; Wan, CP; Wang, XL; Zheng, X | 1 |
| Guo, YX; Liu, EH; Lu, L; Shi, CZ; Zhang, L | 1 |
| Oberoi, AS; Philip, L | 1 |
| Baroncelli, R; Boari, A; Cimmino, A; Evidente, A; Masi, M; Tuzi, A; Vurro, M; Zonno, MC | 1 |
| Bist, G; Kadayat, TM; Kwon, Y; Lee, ES; Lee, HJ; Park, S; Shrestha, A; Thapa Magar, TB | 1 |
| Chand, K; Hiremathad, A; Keri, RS; Santos, MA; Singh, M | 1 |
| Dong, ZZ; Huang, Q; Kang, TS; Leung, CH; Ma, DL; Mok, SW; Wang, W; Wong, VK; Zhong, HJ | 1 |
| Bao, JK; Bao, MY; Li, JZ; Li, YY; Liang, DF; Lu, KM; Luo, H; Sun, R; Wang, X | 1 |
| El-Hawash, SAM; El-Messmary, H; El-Miligy, MMM; Hazzaa, AA; Nassra, RA | 1 |
| Mo, XF; Wei, JL; Xu, XL; Yang, YR; You, QD; Zhang, XJ | 1 |
| Bartolotta, R; Buscemi, S; Delisi, R; Gentile, C; Lauria, A; Martorana, A; Mingoia, F; Palumbo Piccionello, A | 1 |
| Barceló, B; Busardò, FP; Elorza, MÁ; Gomila, I; Kyriakou, C; Marchei, E; Pichini, S; Roset, C; Rotolo, MC | 1 |
| Afifi, M; Chigurupati, S; Imran, S; Rahim, F; Selvaraj, M; Shah, SAA; Taha, M; Ullah, H; Vijayabalan, S; Zaman, K | 1 |
| Yamaguchi, Y | 1 |
| Feng, XY; Fu, YH; Guo, W; Huang, ZH; Jiang, ZH; Liu, YP; Wang, TT; Yue, H | 1 |
| Abd El-Karim, SS; Al-Omar, MA; Khalifa, NM; Saleh, DO; Srour, AM | 1 |
| Adhikary, S; Choudhary, D; Gupta, S; Modukuri, RK; Rao, KB; Sashidhara, KV; Sharma, T; Siddiqi, MI; Trivedi, R | 1 |
| Asrondkar, A; Bobade, AS; Bollikonda, S; Patil, RH; Patil, SR; Reddy, PP; Sangshetti, JN; Shinde, DB | 1 |
| Cao, J; Hu, Q; Huang, S; Lu, B; Shen, R; Tao, W; Wan, H; Wang, D; Yuan, J; Zhang, J; Zhang, L; Zhang, M | 1 |
| Fan, J; Gao, H; Jian, J; Lan, P; Li, M; Liu, P; Sun, P; Yang, H | 1 |
| Colonno, R; Huang, N; Huang, Q; Huq, A; Lau, M; Li, L; Peng, E; Zhong, M | 1 |
| Jin, X; Li, G; Sun, J; Wei, CX; Zhang, Z; Zhou, W | 1 |
| Feroci, M; Gasperi, T; Loreto, MA; Miceli, M; Roma, E; Rosa, P; Tofani, D | 1 |
| Davis, TZ; Green, BT; Lee, ST; Pfister, JA; Stegelmeier, BL | 1 |
| Chand, K; Hiremathad, A; Keri, RS | 1 |
| Adhikary, S; Choudhary, D; Gupta, S; Modukuri, RK; Sashidhara, KV; Trivedi, R | 1 |
| Graczyk, PP; Nerdinger, S; Piotrkowska, B; Schreiner, E; Selič, L | 1 |
| Bassanini, I; Colombo, G; Costa, M; D'Annessa, I; Monti, D; Riva, S | 1 |
| Marimuthu, P; Singaravelu, K | 1 |
| Lashgari, N; Mohammadi Ziarani, G; Mostofi, M | 1 |
| Guo, R; Huang, XX; Lin, B; Song, SJ; Wang, J; Wang, XB; Zhou, L | 1 |
| Airinei, A; Isac, DL; Mangalagiu, I; Moldoveanu, C; Zbancioc, G | 1 |
| Guan, L; Huang, M; Li, B; Li, D; Liu, B; Liu, D; Wang, S; Zang, J; Zhao, L | 1 |
| Fang, L; Han, L; Hu, S; Hu, X; Sun, Q; Wang, M; Wu, H; Zhao, F | 1 |
| Ahmed, SA; Hinz, DJ; Hossain, MM; Jellen, MJ | 1 |
| Chen, Q; Guo, M; Jiang, P; Yang, J | 1 |
| Carella, A; Diana, R; Iannitti, R; La Manna, S; Marasco, D; Palumbo, R; Roviello, GN; Roviello, V; Trifuoggi, M | 1 |
| Aro, A; Choong, YS; Maluleka, MM; McGaw, LJ; Mphahlele, MJ | 1 |
| Aierken, A; Xu, P | 1 |
| Baghel, T; Bhagwati, S; Fatima, S; Gupta, S; Kushwaha, P; Nazir, A; Sashidhara, KV; Siddiqi, MI; Upadhyay, A | 1 |
| Cieślak, MJ; Dolot, R; Królewska-Golińska, K; Napiórkowska, M; Nawrot, B; Radzikowska-Cieciura, E; Sobczak, M; Wybrańska, I | 1 |
| Delogu, F; Delogu, GL; Era, B; Fais, A; Kumar, A; Matos, MJ; Medda, R; Pintus, F | 1 |
| Ahn, KS; Harmalkar, DS; Jeong, HG; Kwon, OK; Lee, G; Lee, K; Lim, Y; Lu, Q; Mali, JR; Oh, SR; Shin, IS; Xu, X | 1 |
| Benaim, G; Hejchman, E; Martinez-Sotillo, N; Pinto-Martínez, A | 1 |
| Cao, JQ; Cheng, MJ; Li, CC; Liu, C; Wang, L; Wang, Y; Yang, XY; Ye, WC; You, XF; Zhong, LP | 1 |
| Khan, ZA; Naqvi, SAR; Sajid, MA; Shahzad, SA; Usman, M | 1 |
| Chen, Y; Gao, X; Guo, H; Huang, Z; Li, H; Li, S; Liu, H; Liu, Z; Tan, H; Xu, J; Zhang, W | 1 |
| Chen, LY; Lin, S; Liu, RH; Ma, GQ; Mei, DY; Shao, F | 1 |
| Cieślak, M; Kaźmierczak-Barańska, J; Królewska-Golińska, K; Napiórkowska, M; Nawrot, B | 1 |
| Bai, LP; Fu, J; Jiang, ZH; Liu, L; Liu, X; Yang, J; Yang, X; Yao, XJ; Zhu, GY | 1 |
| Abbas, HS; Abd El-Karim, SS | 1 |
| Alves, AJS; Cravo, S; Dethoup, T; Kijjoa, A; Mistry, S; Pereira, JA; Pinto, MMM; Silva, AMS | 1 |
| Afridi, S; Amjad, ST; Anbar, HS; El-Gamal, MI; El-Gamal, R; Iqbal, J; Shafique, Z; Zaib, S; Zaraei, SO | 1 |
| Hollert, H; Keiter, SH; Larsson, M; Meyer-Alert, H | 1 |
| Barker, G; Beck, EM; Cowley, A; Gillespie, J; Hamon, V; Jones, P; Luchowska-Stańska, U; Mahajan, P; McElroy, S; Morgan, D; Morrison, A; Pannifer, AD; Parnell, E; Porter, A; Rehmann, H; Robinson, J; Robinson, L; Rutjes, H; Timmerman, M; Wiejak, J; Yarwood, SJ | 1 |
| Cardoso, SM; Chand, K; Chaves, S; Fancellu, G; Orlandini, E; Piemontese, L; Santos, MA; Silva, DF; Tomás, D | 1 |
| Choi, JS; Jung, HA; Min, BS; Paudel, P; Seong, SH; Wagle, A | 1 |
| Abdel-Aziz, HA; Abdelrahman, MA; Abou-Seri, SM; Almahli, H; Eldehna, WM; Ibrahim, HS; Nocentini, A; Supuran, CT | 1 |
| Johansson Holm, L; Oschmann, M; Pourghasemi-Lati, M; Verho, O | 1 |
| Fu, L; Liu, Y; Lu, Y; Sheng, L; Wang, B; Zhang, D; Zhao, H; Zhao, W | 1 |
| Brkljača, R; Elofsson, M; Sundin, C; Urban, S; Vo, DD; Zetterström, CE | 1 |
| Abdolmohammadi, S; Hossaini, Z; Najar, AH; Zareyee, D | 1 |
| Gao, Y; He, X; Hui, Z; Shen, G; Wang, S; Xie, T; Ye, XY | 1 |
| Dong, M; Gao, Q; Hu, QF; Li, J; Li, JG; Li, XM; Li, YK; Liao, LM; Liu, X; Yang, GY; Ye, YQ | 1 |
| Chitneni, PR; Gorityala, N; Irlapati, VK; Mokenapelli, S; Sagurthi, SR; Thalari, G; Vadiyaala, N; Yerrabelli, JR | 1 |
| Bhukya, B; Chaturvedi, V; Khan, F; Kumar, S; Negi, AS; Shukla, A; Srivastava, SK; Trivedi, P | 1 |
| Bhatti, A; Grabovyi, GA; Mohr, JT | 1 |
| Gildenhuys, S; Mphahlele, MJ; Olomola, TO | 1 |
| Guo, HF; Jin, J; Li, ZR; Liu, ZY; Xie, ZS; Xue, ST; Yi, H; Zhang, L | 1 |
| Chen, Y; Guo, ZY; Liu, CX; Liu, ZX; Zhang, QQ; Zhang, ZM; Zhou, JH; Zou, K | 1 |
| Farooq, RK; Nawaz, M; Rahim, F; Shah, SAA; Taha, M; Ullah, H; Wadood, A; Zakaria, ZA | 1 |
| Mekky, AEM; Sanad, SMH | 1 |
| Abugrain, ME; Carpenter, EL; Hadi, S; Indra, A; Indra, G; Mahmud, T; Noviany, N; Purwitasari, N; Samadi, A | 1 |
| Krawczyk, P | 1 |
| Al-Rashida, M; Anbar, HS; El-Gamal, MI; El-Gamal, R; Iqbal, J; Pelletier, J; Sévigny, J; Ullah, S; Zaib, S; Zaraei, SO | 1 |
| Feng, KR; Gao, D; Lin, GQ; Shi, XW; Tian, P; Wang, F; Zhang, JW; Zhao, JY; Zhou, J | 1 |
| Olotu, FA; Soliman, MES; Soremekun, OS; Subair, TI | 1 |
| El-Khouly, OA; El-Messery, SM; El-Sayed, MA; Henen, MA; Shabaan, MI | 1 |
| Bustelo, F; Delogu, GL; Gatto, G; Kumar, A; Laguna, R; Rodríguez-Franco, MI; Saavedra, LM; Viña, D | 1 |
| Bertrand, B; Chang, L; Dechoux, L; Fischer-Durand, N; Gontard, G; Thorimbert, S | 1 |
| BasavanaGowda, MK; Chae, HS; Choi, WJ; Masagalli, JN | 1 |
| Beteck, RM; Legoabe, LJ; Moolman, C; van der Sluis, R | 1 |
| Chan, ECY; Chin, SY; Tan, HL; Tang, LWT | 1 |
| Cheng, M; Gu, Y; Huang, H; Sun, Y; Wang, X; Wu, T; Yan, J; Yin, W; Zhang, X; Zhang, Z; Zhao, D | 1 |
| Abdel-Aziz, MM; Abdelgawad, MA; Al-Ansary, GH; Al-Sanea, MM; Bukhari, SNA; Eldehna, WM; Elkaeed, EB; Elsayed, ZM; Maklad, RM; Suliman, H | 1 |
| Chowdhury, SR; Fu, L; Gu, J; Hu, Y; Jiang, F; Lam, C; Lei, S; Lu, D; Tavallaie, MS; Wang, J | 1 |
| Kaur, N; Kaur, P; Kumar, V; Nayak, SK; Sahu, SK; Wadhwa, P | 1 |
| Abdel-Aziz, HA; Abdulla, MH; Ahmad, R; Al-Warhi, T; Ayyad, RR; El-Haggar, R; Eldehna, WM; Elsayed, ZM; Knany, HR; Salem, R; Traiki, TB | 1 |
| Duan, Y; Wang, Y | 1 |
| Abbott, BM; Dhouib, R; Duncan, LF; Heras, B; Ilyichova, OV; Scanlon, MJ; Totsika, M; Wang, G | 1 |
| Casapullo, A; Cassiano, C; Colombo, G; Costantini, M; Fassi, EMA; Morretta, E; Sattin, S | 1 |
| Amit, I; Bercovich, A; Chen, LYY; David, E; Hoekstra, ME; Li, H; Lubling, Y; Reinalda, L; Scheele, CLGJ; Schumacher, TN; Tanay, A; Thommen, DS; Toebes, M; van de Graaff, MJ; van der Leun, AM; van Kasteren, SI; van Rheenen, J | 1 |
| Anh Thu, P; Hai Dang, N; Thanh Huong, L; Thi Dao, P; Thi Mai Huong, D; Van Cuong, P | 1 |
| Xu, D; Xu, Z; Zhang, X; Zhou, W | 1 |
| Fu, L; Hu, Y; Jiang, F; Lei, S; Lu, D; Sun, R; Wang, J; Yuan, C; Zhang, Y | 1 |
| Basilico, N; Butini, S; Campiani, G; D'Alessandro, S; Gemma, S; Ibba, R; Parapini, S; Pozzetti, L; Rossi, S; Taglialatela-Scafati, O; Taramelli, D | 1 |
| De Stefano, C; Fontanella, F; Palumbo, R; Roviello, GN; Scognamiglio, PL; Vicidomini, C | 1 |
| Coskun, D; Coskun, MF; Gunduz, B | 1 |
| Abdel-Aziz, HA; Abourehab, MAS; Al-Warhi, T; Almahli, H; El Kerdawy, AM; Eldehna, WM; Elkaeed, EB; Maklad, RM | 1 |
| Ameta, KL; Chundawat, RS; Devi, AP; Dhingra, N | 1 |
| Abbas, AA; Dawood, KM | 1 |
17 review(s) available for benzofuran and benzofurans
| Article | Year |
|---|---|
Benzofuran.
Topics: Animals; Benzofurans; Carcinogenicity Tests; Carcinogens; Humans | 1995 |
Solid phase chemical technologies for combinatorial chemistry.
Topics: Benzofurans; Combinatorial Chemistry Techniques; Cyclization; Free Radicals; Furans; Indoles; Molecular Conformation; Piperazines | 2001 |
Medicinal chemistry and biological properties of non-imidazole histamine H3 antagonists.
Topics: Animals; Benzofurans; Histamine Antagonists; Humans; Imidazoles; Receptors, Histamine H3; Structure-Activity Relationship | 2004 |
Development of positron-emission tomography/single-photon emission computed tomography imaging probes for in vivo detection of beta-amyloid plaques in Alzheimer's brains.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzofurans; Brain; Flavonoids; Humans; Positron-Emission Tomography; Radiopharmaceuticals; Stilbenes; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2009 |
Synthesis of bicyclonucleosides having a C-C bridge.
Topics: Benzofurans; Bridged Bicyclo Compounds; Carbon; Cyclobutanes; Cyclohexanes; Cyclopentanes; Cyclopropanes; Nucleosides; Spiro Compounds | 2010 |
Bioactive benzofuran derivatives: moracins A-Z in medicinal chemistry.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antioxidants; Benzofurans; Chemistry, Pharmaceutical; Humans; Immunologic Factors | 2015 |
Bioactive Benzofuran derivatives: A review.
Topics: Animals; Benzofurans; Drug Design; Drug Discovery; Humans; Molecular Structure; Structure-Activity Relationship | 2015 |
Bioactive benzofuran derivatives: An insight on lead developments, radioligands and advances of the last decade.
Topics: Animals; Benzofurans; Biological Products; Drug Design; Drug Discovery; Humans; Radiopharmaceuticals | 2015 |
High-throughput drug repositioning for the discovery of new treatments for Chagas disease.
Topics: Benzofurans; Chagas Disease; Computational Biology; Drug Repositioning; High-Throughput Screening Assays; Humans; Trypanocidal Agents; Trypanosoma cruzi | 2015 |
Biological and medicinal significance of benzofuran.
Topics: Animals; Benzofurans; Drug Discovery; Humans | 2015 |
Alkenylation of Arenes and Heteroarenes with Alkynes.
Topics: Alkynes; Benzofurans; Catalysis; Heterocyclic Compounds; Indoles; Metals, Heavy; Quinolines; Transition Elements | 2016 |
A review on antioxidant potential of bioactive heterocycle benzofuran: Natural and synthetic derivatives.
Topics: Antioxidants; Benzofurans; Drug Design; Drug Discovery; Heterocyclic Compounds; Humans; Structure-Activity Relationship | 2017 |
Synthesis of Furanocoumarin, Benzofuran and Coumarin Derivatives Possessing an Inhibitory Effect on Human CYP, and Elucidation of the Inhibitory Mechanism.
Topics: Benzofurans; Citrus paradisi; Coumarins; Cytochrome P-450 CYP3A Inhibitors; Fruit and Vegetable Juices; Furocoumarins; Humans; Structure-Activity Relationship | 2017 |
5-Endo-dig cyclizations in organic syntheses.
Topics: Benzofurans; Catalysis; Chemistry Techniques, Synthetic; Coumarins; Cyclization; Indoles; Molecular Structure | 2020 |
Alpha-amylase as molecular target for treatment of diabetes mellitus: A comprehensive review.
Topics: 1-Deoxynojirimycin; Acarbose; alpha-Amylases; Benzofurans; Blood Glucose; Diabetes Mellitus; Drug Discovery; Flavonoids; Glycoside Hydrolase Inhibitors; Humans; Hydrazones; Hypoglycemic Agents; Indoles; Inositol; Oxadiazoles; Structure-Activity Relationship | 2021 |
Therapeutic Potential of Naturally Occurring Benzofuran Derivatives and Hybrids of Benzofurans with other Pharmacophores as Antibacterial Agents.
Topics: Anti-Bacterial Agents; Benzofurans; Humans; Structure-Activity Relationship | 2022 |
Benzofuran as a promising scaffold for the synthesis of novel antimicrobial agents.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Benzofurans; Drug Design; Humans; Staphylococcus aureus; Structure-Activity Relationship | 2022 |
1 trial(s) available for benzofuran and benzofurans
| Article | Year |
|---|---|
Transmammary transfer of toxicity to nursing kids from Isocoma pluriflora (rayless goldenrod) dosed to lactating goats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Asteraceae; Benzofurans; Creatine Kinase; Female; Goat Diseases; Goats; Ketones; Lactation; Milk; Muscular Diseases; Necrosis; Plant Poisoning; Plants, Toxic | 2018 |
340 other study(ies) available for benzofuran and benzofurans
| Article | Year |
|---|---|
The conformation and activity relationship of benzofuran derivatives as angiotensin II receptor antagonists.
Topics: Angiotensin Receptor Antagonists; Benzofurans; Magnetic Resonance Spectroscopy; Molecular Structure | 1997 |
[A study of the mechanism of lidocaine and befol effects on Na-exchange in normal cardiomyocytes and in the experimental model of hypoxia in vitro].
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Benzamides; Benzofurans; Cell Hypoxia; Cells, Cultured; Enzyme Inhibitors; Heart; Lidocaine; Morpholines; Myocardium; Ouabain; Rats; Sodium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence | 1996 |
Benzofuran based PDE4 inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Benzofurans; Cyclic Nucleotide Phosphodiesterases, Type 4; Endotoxemia; Enzyme Inhibitors; Male; Mice; Mice, Inbred BALB C; Structure-Activity Relationship | 1999 |
A cinnamoyl esterase from Aspergillus niger can break plant cell wall cross-links without release of free diferulic acids.
Topics: Absorption; Aspergillus niger; Benzofurans; Carboxylic Ester Hydrolases; Catalysis; Cell Wall; Chromatography, High Pressure Liquid; Cinnamates; Cross-Linking Reagents; Dimerization; Esterases; Hydrogen-Ion Concentration; Hydrolysis; Ions; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Oligosaccharides; Plants; Substrate Specificity; Time Factors; Zea mays | 1999 |
(-)1-(Benzofuran-2-yl)-2-propylaminopentane, [(-)BPAP], a selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain.
Topics: Animals; Benzofurans; Brain; Cells, Cultured; Dopamine; Electric Stimulation; Mice; Norepinephrine; Phenethylamines; Psychotropic Drugs; Rabbits; Rats; Receptors, Catecholamine; Receptors, Serotonin; Serotonin; Tryptamines | 1999 |
The conformation and activity relationship of benzofuran type of angiotensin II receptor antagonists.
Topics: Algorithms; Angiotensin Receptor Antagonists; Benzofurans; Binding, Competitive; Drug Design; Humans; Imidazoles; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Protein Binding; Quantitative Structure-Activity Relationship; Tetrazoles | 2000 |
Enantioselective synthesis and absolute configuration of (-)-1-(benzofuran-2-yl)-2-propylaminopentane, ((-)-BPAP), a highly potent and selective catecholaminergic activity enhancer.
Topics: Azirines; Benzofurans; Catecholamines; Crystallography, X-Ray; Molecular Conformation; Molecular Structure; Stereoisomerism | 2001 |
Theoretical investigation of (-)1-(benzofuran-2-yl)-2-propylaminopentane[(-)-BPAP] as a hydroxyl radical scavenger.
Topics: Benzofurans; Carbon; Computational Biology; Energy Metabolism; Free Radical Scavengers; Hydroxyl Radical; Models, Molecular; Molecular Conformation; Spin Labels | 2001 |
Total synthesis and determination of the absolute configuration of frondosin B.
Topics: Aldehydes; Benzofurans; Heterocyclic Compounds, 4 or More Rings; Molecular Conformation; Receptors, Interleukin-8A; Stereoisomerism | 2001 |
Anionic cyclization approach toward perhydrobenzofuranone: stereocontrolled synthesis of the hexahydrobenzofuran subunit of avermectin.
Topics: Anions; Anthelmintics; Benzofurans; Ivermectin; Molecular Structure; Spectrum Analysis | 2002 |
Angiotensin II directly stimulates ENaC activity in the cortical collecting duct via AT(1) receptors.
Topics: Amiloride; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Benzofurans; Biphenyl Compounds; Hydrogen-Ion Concentration; Intracellular Membranes; Ionophores; Kidney Tubules, Collecting; Losartan; Mice; Microscopy, Fluorescence; Monensin; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Signal Transduction; Sodium Chloride; Tetrazoles | 2002 |
A convergent synthetic approach using sterically demanding aryldipyrrylmethanes for tuning the pocket sizes of cofacial bisporphyrins.
Topics: Benzofurans; Catalysis; Crystallography, X-Ray; Cyclization; Iron; Magnetic Resonance Spectroscopy; Manganese; Metalloporphyrins; Methane; Molecular Conformation; Molecular Structure; Stereoisomerism; Xanthenes; Zinc | 2002 |
Palladium(II)-mediated cascade carbonylative annulation of o-alkynyl-phenols on silyl linker-based macrobeads: a combinatorial synthesis of a 2,3-disubstituted benzo[b]furan library.
Topics: Alkynes; Benzofurans; Biological Factors; Carbon Monoxide; Catalysis; Combinatorial Chemistry Techniques; Palladium; Phenols; Resins, Synthetic | 2002 |
Application of directly coupled high performance liquid chromatography-NMR-mass spectometry and 1H NMR spectroscopic studies to the investigation of 2,3-benzofuran metabolism in Sprague-Dawley rats.
Topics: Animals; Benzofurans; Chromatography, High Pressure Liquid; Male; Mass Spectrometry; Nuclear Magnetic Resonance, Biomolecular; Rats; Rats, Sprague-Dawley | 2002 |
Differentiation-dependent levels of benzofuran-type resveratrol dimers in root cultures of Anigozanthos preissii.
Topics: Benzofurans; Dimerization; Magnetic Resonance Spectroscopy; Magnoliopsida; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Resveratrol; Stilbenes | 2003 |
[Research on the benzofuran series. III. Study of the thyroid function in man during the administration of an iodized bensofuran derivative (Benziodarone)].
Topics: Benzofurans; Furans; Iodides; Iodine; Research; Thyroid Gland | 1961 |
[Studies on the coronary vasodilator properties of 2-ethyl-3-(3, 5-diiodo-4-hydroxybenzoyl)-coumarone].
Topics: Benzofurans; Coumarins; Vasodilator Agents | 1960 |
The synthesis and antifungal studies of some benzofuran compounds.
Topics: Antifungal Agents; Benzofurans; Furans | 1960 |
[Research on the benzofuran series. IV. Transport and metabolism of 2-ethyl-3-(4-hydroxy-3,5-diiodobenzoyl)-benzofuran in animal and man].
Topics: Animals; Benzofurans; Biological Transport; Coumarins; Humans; Male | 1961 |
[Spasmolytic ketones derived from benzofuran].
Topics: Benzofurans; Furans; Ketones; Muscle Relaxants, Central; Parasympatholytics | 1961 |
[Furans and pyrans. 2. The preparation of 2-monthyl-4-oxo-4,5,6,7-tetrahydro-benzofuran and 2-phenlyl-5-oxo-5,6,7,8-tetrahydrobenzopyran].
Topics: Benzofurans; Furans; Oxotremorine; Pyrans | 1962 |
[Studies in the benzofuran series. VII. Preliminary pharmacological study of 2-butyl-3-(3,5-diiodo-4-beta-N-diethylaminoethoxybenzoyl)-benzofuran].
Topics: Benzofurans; Blood Circulation; Coronary Vessels; Furans; Heart; Muscle, Smooth; Muscles | 1962 |
[Studies in the benzofuran series. V. Alkyl-hydroxybenzoyl-benzofurans with analgesic activity].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Benzofurans; Furans | 1962 |
[Studies in the benzofuran series. VI. Coronary-dilating activity of alkylated and aminoalkylated derivatives of 3-benzoylbenzofuran].
Topics: Alkylation; Benzofurans; Coronary Vessels; Furans; Heart; Humans; Vasodilator Agents | 1962 |
[RESEARCH IN THE BENZOFURAN SERIES. VIII. EFFECTS OF CERTAIN BENZOFURAN DERIVATIVES ON CAPILLARY FRAGILITY AND PERMEABILITY].
Topics: Benzofurans; Capillary Fragility; Capillary Permeability; Capillary Resistance; Furans; Permeability; Pharmacology; Rats; Research | 1963 |
[CLINICAL EVALUATION OF THE ACTION OF 2-ETHYL-3-(4-HYDROXY-3-6 DIIODOBENZOYL) BENZOFURAN (BENZIODARONE) IN CORONARY INSUFFICIENCY].
Topics: Benzofurans; Coronary Artery Disease; Coronary Disease; Furans; Humans; Vasodilator Agents | 1963 |
[ON 2-FORMYL-1,4-BENZODIOXANE AND ON 2-FORMYL-2,3-DIHYDRO-BENZOFURAN].
Topics: Benzofurans; Chemistry, Pharmaceutical; Dioxins; Furans; Pharmacy; Piperoxan | 1964 |
[DERIVATIVES OF BENZOFURAN AND COUMARIN. III. BETA-ALANINAMIDES OF THE 2-ETHYL-3-METHYLBENZOFURAN AND 2-ETHYL-3-METHYLCOUMARIN SERIES].
Topics: Antihypertensive Agents; Benzofurans; Chemistry, Pharmaceutical; Coumarins; Furans; Mice; Pharmacology; Research | 1964 |
[RESEARCH IN THE BENZOFURAN SERIES. XII. EFFECT OF MUSCLE THYROXINE-DESIODASE ON IODINATED DERIVATIVES OF 4'-HYDROXY-3-BENZOYLFURAN].
Topics: Benzofurans; Biochemical Phenomena; Biochemistry; Diiodotyrosine; Enzymes; Furans; Muscle Relaxants, Central; Muscles; Research; Thyroxine; Vasodilator Agents | 1964 |
[EFFECTS OF 2-ETHYL-(3,5-DIIODO-4-HYDROXYBENZOYL)-3-BENZOFURAN ON THYROID UPTAKE OF RADIOACTIVE IODINE AND ON SERUM PROTEIN-BOUND IODINE].
Topics: Benzofurans; Blood Proteins; Furans; Iodine; Iodine Isotopes; Pharmacology; Thyroid Function Tests; Thyroid Gland; Vasodilator Agents | 1964 |
[THE EFFECTS OF 2-ETHYL-3-(3',5'-DIIODO-4'-HYDROXYBENZOYL)-BENZOFURAN ON THE BLOOD CIRCULATION OF VARIOUS ORGANS IN THE CAT].
Topics: Benzofurans; Blood Circulation; Brain; Cats; Heart; Liver Circulation; Muscles; Pharmacology; Research; Vasodilator Agents | 1964 |
[RESEARCH IN THE BENZOFURAN SERIES. X. PHARMACOLOGIC AND TOXICOLOGIC STUDY OF 2-ETHYL-3-(4-HYDROXYBENZOYL)-BENZOFURAN].
Topics: Benzofurans; Capillary Permeability; Capillary Resistance; Dogs; Furans; Injections; Injections, Intraperitoneal; Pharmacology; Rabbits; Rats; Research; Toxicology | 1965 |
[Treatment of coronary insufficiency with ethyl(diiodohydroxybenzoyl) benzofuran].
Topics: Benzofurans; Coronary Artery Disease; Coumarins; Heart Failure; Humans | 1961 |
Preparation of 3-acetoacetylaminobenzo[b]furan derivatives with cysteinyl leukotriene receptor 2 antagonistic activity.
Topics: Asthma; Benzofurans; Chemistry, Organic; Crystallography, X-Ray; Humans; Leukotriene Antagonists; Membrane Proteins; Models, Chemical; Models, Molecular; Receptors, Leukotriene | 2003 |
Novel synthesis of isoquinolines using isobenzofuran-nitrile Diels-Alder reactions.
Topics: Benzofurans; Isoquinolines; Nitriles | 2003 |
4-Hydroxy-3-methyl-6-phenylbenzofuran-2-carboxylic acid ethyl ester derivatives as potent anti-tumor agents.
Topics: Antineoplastic Agents; Benzofurans; Carboxylic Acids; Cell Line, Tumor; Esters; Humans | 2004 |
Synthesis of 5-chloro-3-[4-(3-diethylaminopropoxy)benzoyl]-2-(4-methoxyphenyl)benzofuran as a beta-amyloid aggregation inhibitor.
Topics: Amyloid beta-Peptides; Benzofurans; Structure-Activity Relationship | 2003 |
Constituents of two Flourensia species.
Topics: Asteraceae; Benzofurans; Flavonoids; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Plant Components, Aerial; Plant Extracts | 2004 |
Antimicrobial activities of hydrophobic 2-arylbenzofurans and an isoflavone against vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Benzofurans; Enterococcus; Glycyrrhiza uralensis; Humans; Isoflavones; Methicillin Resistance; Microbial Sensitivity Tests; Phytotherapy; Plant Extracts; Staphylococcus aureus; Vancomycin Resistance | 2004 |
DNA damage and micronuclei induced in rat and human kidney cells by six chemicals carcinogenic to the rat kidney.
Topics: Animals; Benzofurans; Captan; Carcinogenicity Tests; Carcinogens; Cells, Cultured; Cyclohexenes; DNA Damage; Dose-Response Relationship, Drug; Female; Humans; Kidney; Male; Micronuclei, Chromosome-Defective; Nitrobenzenes; Ochratoxins; Rats; Rats, Sprague-Dawley; Species Specificity; Trichloroethylene; Trihalomethanes | 2004 |
Gymnastone, a new benzofuran derivative from Gymnaster koraiensis.
Topics: Acetylene; Asteraceae; Benzofurans; Chromatography; Glycosides; Plant Extracts; Plant Stems | 2004 |
Antileishmanial activity, cytotoxicity and QSAR analysis of synthetic dihydrobenzofuran lignans and related benzofurans.
Topics: Animals; Antiprotozoal Agents; Benzofurans; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Leishmania; Lignans; Quantitative Structure-Activity Relationship | 2005 |
Structure-activity relationships of arylbenzofuran H3 receptor antagonists.
Topics: Benzofurans; Histamine H1 Antagonists; Pyrrolidines; Receptors, Histamine H3; Structure-Activity Relationship | 2005 |
Achievement of behavioral efficacy and improved potency in new heterocyclic analogs of benzofuran H3 antagonists.
Topics: Animals; Behavior, Animal; Benzofurans; Cyclization; Histamine Antagonists; Humans; Molecular Structure; Rats; Receptors, Histamine H3 | 2005 |
A benzoisofuranone derivative and carbazole alkaloids from Murraya koenigii and their antimicrobial activity.
Topics: Alkaloids; Anti-Infective Agents; Benzofurans; Carbazoles; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Murraya; Plant Stems | 2005 |
Synthesis and biological evaluation of novel angularly fused polycyclic coumarins.
Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Benzofurans; Colony Count, Microbial; Coumarins; Heterocyclic Compounds, 4 or More Rings; Pain Measurement; Pyridines; Structure-Activity Relationship | 2005 |
Benzofuran- and furan-2-yl-(phenyl)-3-pyridylmethanols: synthesis and inhibition of P450 aromatase.
Topics: Aromatase; Aromatase Inhibitors; Benzofurans; Enzyme Inhibitors; Furans; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Methanol; Microsomes; Models, Chemical; Models, Molecular; Placenta; Protein Binding; Protons; Software; Temperature | 2005 |
Identification of potent and selective MMP-13 inhibitors.
Topics: Administration, Oral; Amino Acids; Animals; Benzofurans; Cartilage; Cattle; Chelating Agents; Collagenases; Crystallography, X-Ray; Drug Design; In Vitro Techniques; Inhibitory Concentration 50; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Models, Molecular; Protease Inhibitors; Protein Structure, Tertiary; Rats; Sensitivity and Specificity; Structure-Activity Relationship; Substrate Specificity; Zinc | 2005 |
Benzothieno and benzofurano annelated estranes.
Topics: Azo Compounds; Benzofurans; Catalysis; Cyclization; Estranes; Molecular Structure | 2005 |
Syntheses of tetrahydrofurobenzofurans and dihydromethanobenzodioxepines from 5-hydroxy-3-methyl-3H-benzofuran-2-one. Rearrangement and ring expansion under reductive conditions on treatment with hydrides.
Topics: Benzofurans; Cholinesterase Inhibitors; Cholinesterases; Hot Temperature; Magnetic Resonance Spectroscopy; Molecular Structure; Oxepins | 2005 |
Structure, dipole moment and large amplitude motions of 1-benzofuran.
Topics: Benzofurans; Models, Chemical; Spectroscopy, Fourier Transform Infrared | 2005 |
Direct effects of aldosterone on cardiomyocytes in the presence of normal and elevated extracellular sodium.
Topics: Aldosterone; Amides; Animals; Benzofurans; Cells, Cultured; Eplerenone; Hemodynamics; Hypertrophy; Indoles; Leucine; Mineralocorticoid Receptor Antagonists; Myocytes, Cardiac; Phthalic Acids; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sodium; Sodium-Hydrogen Exchangers; Spironolactone; Time Factors | 2006 |
Synthesis of novel benzofuran isoxazolines as protein tyrosine phosphatase 1B inhibitors.
Topics: Benzofurans; Benzopyrans; Drug Design; Enzyme Inhibitors; Hypoglycemic Agents; Isoxazoles; Millettia; Models, Chemical; Oxazolone; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases | 2006 |
Synthesis, anticonvulsant, and anti-inflammatory evaluation of some new benzotriazole and benzofuran-based heterocycles.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Benzofurans; Cyclooxygenase 2 Inhibitors; Drug Evaluation, Preclinical; Heterocyclic Compounds; Mice; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2006 |
Synthesis and oxidant properties of novel (5-bromobenzofuran-2-yl)(3-methyl-3-mesitylcyclobutyl)ketonethiosemicarbazone.
Topics: Animals; Antioxidants; Benzofurans; Male; Molecular Structure; Oxidants; Rats; Rats, Wistar; Thiosemicarbazones | 2006 |
Synthesis and antifungal activities of some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl) benzofuran-2-yl] ketoximes.
Topics: Antifungal Agents; Azoles; Benzofurans; Candida; Imidazoles; Methylation; Molecular Structure; Oximes; Structure-Activity Relationship | 2006 |
Novel benzofuran derivatives for PET imaging of beta-amyloid plaques in Alzheimer's disease brains.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzofurans; Mice; Mice, Transgenic; Molecular Structure; Positron-Emission Tomography | 2006 |
Novel benzofuran inhibitors of human mitogen-activated protein kinase phosphatase-1.
Topics: Benzofurans; cdc25 Phosphatases; Cell Cycle Proteins; Dual Specificity Phosphatase 3; Dual Specificity Phosphatase 6; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Inhibitory Concentration 50; Kinetics; Mitogen-Activated Protein Kinase 1; Phosphorylation; Protein Phosphatase 1; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Substrate Specificity | 2006 |
Fluorescent benzofuran histamine H(3) receptor antagonists with sub-nanomolar potency.
Topics: Benzofurans; Fluorescence; Histamine Antagonists; Ligands; Receptors, Histamine H3 | 2006 |
The reaction of o-alkynylarene and heteroarene carboxaldehyde derivatives with iodonium ions and nucleophiles: a versatile and regioselective synthesis of 1H-isochromene, naphthalene, indole, benzofuran, and benzothiophene compounds.
Topics: Aldehydes; Alkynes; Benzofurans; Benzopyrans; Heterocyclic Compounds; Indoles; Ions; Naphthalenes; Onium Compounds; Pyridines; Thiophenes | 2006 |
Fancy bioisosteres: novel paracyclophane derivatives as super-affinity dopamine D3 receptor antagonists.
Topics: Amides; Animals; Benzene Derivatives; Benzofurans; Binding Sites; Bridged-Ring Compounds; Central Nervous System Agents; CHO Cells; Corpus Striatum; Cricetinae; Cricetulus; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Mutation; Radioligand Assay; Receptors, Dopamine D3; Stereoisomerism; Structure-Activity Relationship; Swine; Thymidine | 2006 |
Use of benzofuran for concomitant protection of aldehyde and phenol groups in the preparation of mycophenolic acid analogues.
Topics: Aldehydes; Benzofurans; Molecular Structure; Mycophenolic Acid; Phenols; Stereoisomerism | 2006 |
Investigation of a convergent route to purpuromycin: benzofuran formation vs spiroketalization.
Topics: Benzofurans; Molecular Structure; Naphthoquinones; Spiro Compounds | 2006 |
Drug-induced thyrotoxicosis: the surgical option.
Topics: Aged; Aged, 80 and over; Amiodarone; Angiogenesis Inhibitors; Anti-Arrhythmia Agents; Benzofurans; Female; Humans; Interferon-alpha; Male; Middle Aged; Risk Factors; Thyroidectomy; Thyrotoxicosis | 2007 |
Novel heterocyclic-substituted benzofuran histamine H3 receptor antagonists: in vitro properties, drug-likeness, and behavioral activity.
Topics: Animals; Behavior, Animal; Benzofurans; Dogs; Haplorhini; Histamine Antagonists; Humans; Rats; Receptors, Histamine H3 | 2007 |
Stereoselective syntheses of the 2-Isopropenyl-2,3-dihydrobenzofuran nucleus: potential chiral building blocks for the syntheses of tremetone, hydroxytremetone, and rotenone.
Topics: Benzofurans; Molecular Structure; Plant Extracts; Rotenone; Stereoisomerism; Triamterene | 2007 |
Electrosynthesis of symmetric and highly conjugated benzofuran via a unique ECECCC electrochemical mechanism: evidence for predominance of electrochemical oxidation versus intramolecular cyclization.
Topics: Benzofurans; Cyclization; Electrochemistry; Molecular Structure; Oxidation-Reduction; Stereoisomerism | 2007 |
Synthesis and SAR of selective benzothiophene, benzofuran, and indole-based peroxisome proliferator-activated receptor delta agonists.
Topics: Animals; Benzofurans; Chemistry, Pharmaceutical; Drug Design; Drug Evaluation, Preclinical; Humans; Indoles; Inhibitory Concentration 50; Ligands; Models, Chemical; PPAR delta; Structure-Activity Relationship; Thiazoles; Thiophenes | 2007 |
Analysis of organic acid markers relevant to inherited metabolic diseases by ultra-performance liquid chromatography/tandem mass spectrometry as benzofurazan derivatives.
Topics: Acids; Benzofurans; Biomarkers; Case-Control Studies; Chromatography, Liquid; Humans; Metabolism, Inborn Errors; Organic Chemicals; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Temperature; Time Factors | 2007 |
Occurrence of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in Lake Maggiore (Italy and Switzerland).
Topics: Benzofurans; Dioxins; Ecosystem; Environmental Monitoring; Fresh Water; Geologic Sediments; Italy; Polybrominated Biphenyls; Polychlorinated Biphenyls; Switzerland; Water; Water Pollutants, Chemical; Water Pollution, Chemical | 2007 |
1-Oxo-5-hydroxytryptamine: a surprisingly potent agonist of the 5-HT3 (serotonin) receptor.
Topics: Benzofurans; Humans; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists | 2007 |
A new 2-arylbenzofuran from the root bark of Chinese Morus cathayana.
Topics: Benzofurans; Humans; Medicine, Chinese Traditional; Morus; Phytotherapy; Plant Bark; Plant Roots | 2007 |
Pyrazole-based cathepsin S inhibitors with improved cellular potency.
Topics: Animals; Aza Compounds; Benzofurans; Carboxylic Acids; Cathepsins; Humans; Indoles; Molecular Structure; Protease Inhibitors; Pyrazoles; Structure-Activity Relationship; Thiophenes | 2007 |
Total synthesis of (-)-episilvestrol and (-)-silvestrol.
Topics: Benzofurans; Macrocyclic Compounds; Models, Chemical; Molecular Structure; Triterpenes | 2007 |
Synthesis and anti-inflammatory evaluation of methylene bridged benzofuranyl imidazo[2,1-b][1,3,4]thiadiazoles.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzofurans; Cross-Linking Reagents; Female; Imidazoles; Male; Methylation; Mice; Models, Molecular; Molecular Structure; Rats; Structure-Activity Relationship; Thiadiazoles | 2008 |
Molecular switch for CLC-K Cl- channel block/activation: optimal pharmacophoric requirements towards high-affinity ligands.
Topics: Animals; Benzofurans; Binding, Competitive; Chloride Channels; CLC-2 Chloride Channels; Humans; Ligands; Niflumic Acid; Patch-Clamp Techniques; Protein Isoforms; Rats; Xenopus laevis | 2008 |
Potent, selective, orally bioavailable inhibitors of tumor necrosis factor-alpha converting enzyme (TACE): discovery of indole, benzofuran, imidazopyridine and pyrazolopyridine P1' substituents.
Topics: ADAM Proteins; ADAM17 Protein; Administration, Oral; Animals; Benzofurans; Biological Availability; Humans; Hydroxamic Acids; Imidazoles; Indoles; Lipopolysaccharides; Matrix Metalloproteinase Inhibitors; Molecular Structure; Protease Inhibitors; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2008 |
Benzofuran-derived cyclic beta-amino acid scaffold for building a diverse set of flavonoid-like probes and the discovery of a cell motility inhibitor.
Topics: Amino Acids, Cyclic; Animals; Benzofurans; Cell Movement; Flavonoids; Mice; Molecular Probes; NIH 3T3 Cells | 2008 |
Minimization of potential hERG liability in histamine H3 receptor antagonists.
Topics: Animals; Behavior, Animal; Benzofurans; Cyclobutanes; Histamine H3 Antagonists; Humans; Male; Molecular Structure; Naphthalenes; Radioligand Assay; Rats; Receptors, Histamine H3; Trans-Activators; Transcriptional Regulator ERG | 2008 |
'Hybrid' benzofuran-benzopyran congeners as rigid analogs of hallucinogenic phenethylamines.
Topics: Animals; Benzofurans; Benzopyrans; DOM 2,5-Dimethoxy-4-Methylamphetamine; Hallucinogens; Ligands; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Stereoisomerism | 2008 |
Characterization of compounds from the roots of Saposhnikovia divaricata by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
Topics: Amino Acid Sequence; Amino Acids; Apiaceae; Benzofurans; Chromatography, High Pressure Liquid; Chromones; Coumarins; Glycosides; Molecular Structure; Plant Roots; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors | 2008 |
Oxidative rearrangements of isobenzofurans: studies toward the synthesis of the ajudazols.
Topics: Ascomycota; Benzofurans; Biological Products; Coumarins; Crystallography, X-Ray; Models, Molecular; Molecular Structure; Oxidation-Reduction | 2008 |
[New neolignan from seed of Myristica fragrans].
Topics: Allylbenzene Derivatives; Benzofurans; Benzyl Compounds; Dioxolanes; Eugenol; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Myristica; Pyrogallol; Safrole; Seeds | 2008 |
Molecular mechanism of hepatitis C virus replicon variants with reduced susceptibility to a benzofuran inhibitor, HCV-796.
Topics: Antiviral Agents; Benzofurans; Cell Line, Tumor; Cloning, Molecular; Drug Resistance, Viral; Enzyme Inhibitors; Genetic Variation; Genotype; Hepacivirus; Humans; Models, Molecular; Mutation; Replicon; RNA-Dependent RNA Polymerase; Viral Nonstructural Proteins | 2008 |
Design and synthesis of 3-pyrrol-3-yl-3H-isobenzofuran-1-ones as inhibitors of human cytosolic phospholipase A2alpha.
Topics: Benzofurans; Blood Platelets; Drug Design; Enzyme Inhibitors; Group IV Phospholipases A2; Humans; Molecular Structure; Pyrroles; Structure-Activity Relationship | 2008 |
Benzofuran derivatives from Eupatorium fortunei.
Topics: Benzofurans; Eupatorium; Glucosides; Magnetic Resonance Spectroscopy; Medicine, Chinese Traditional; Molecular Structure; Plants, Medicinal | 2008 |
Diazonamide support studies: stereoselective formation of the C10 chiral center in both the CDEFG and AEFG fragments.
Topics: Benzofurans; Heterocyclic Compounds, 4 or More Rings; Indoles; Oxazoles; Oxindoles; Stereoisomerism; Substrate Specificity; Tyrosine | 2008 |
One-pot synthesis of benzofurans via palladium-catalyzed enolate arylation with o-bromophenols.
Topics: Benzofurans; Catalysis; Ketones; Palladium; Phenols | 2008 |
Cycloaddition across the benzofuran ring as an approach to the morphine alkaloids.
Topics: Benzofurans; Morphine | 2008 |
Aminostyrylbenzofuran derivatives as potent inhibitors for Abeta fibril formation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzofurans; Benzothiazoles; Benzoxazoles; Chemistry, Pharmaceutical; Curcumin; Drug Design; Electrons; Humans; Inhibitory Concentration 50; Models, Chemical; Peptide Fragments; Structure-Activity Relationship; Styrenes; Thiazoles | 2008 |
Antibacterial properties of 3 H-spiro[1-benzofuran-2,1'-cyclohexane] derivatives from Heliotropium filifolium.
Topics: Anti-Infective Agents; Benzofurans; Cyclohexanes; Gram-Negative Bacteria; Gram-Positive Bacteria; Heliotropium; Hydrophobic and Hydrophilic Interactions; Microbial Sensitivity Tests; Molecular Structure; Plant Extracts; Spiro Compounds; Structure-Activity Relationship | 2008 |
On a few new derivatives of the coumarane.
Topics: Benzofurans | 1947 |
Effect of periodic replacement of the heteroatom on the spectroscopic properties of indole and benzofuran derivatives.
Topics: Absorption; Benzofurans; Circular Dichroism; Crystallography, X-Ray; Electrons; Indoles; Magnetics; Quantum Theory; Time Factors | 2009 |
Ivermectin-derived leishmanicidal compounds.
Topics: Animals; Benzofurans; Disaccharides; Ivermectin; Leishmania mexicana; Macrophages; Mice; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents | 2009 |
Application of a rhodium-catalyzed addition/cyclization sequence toward the synthesis of polycyclic heteroaromatics.
Topics: Alkenes; Benzofurans; Boronic Acids; Catalysis; Cyclization; Esters; Heterocyclic Compounds; Indoles; Polycyclic Compounds; Rhodium; Thiophenes | 2009 |
Total synthesis of the potent anticancer Aglaia metabolites (-)-silvestrol and (-)-episilvestrol and the active analogue (-)-4'-desmethoxyepisilvestrol.
Topics: Aglaia; Antineoplastic Agents, Phytogenic; Benzofurans; Cell Line, Tumor; Cell Proliferation; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Triterpenes | 2009 |
Prenylated arylbenzofuran derivatives from Morus mesozygia with antioxidant activity.
Topics: Antioxidants; Benzofurans; Free Radicals; Magnetic Resonance Spectroscopy; Molecular Structure; Morus; Neoprene | 2009 |
Synthesis and structure-activity relationships of novel benzofuran farnesyltransferase inhibitors.
Topics: Animals; Antineoplastic Agents; Benzofurans; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Inhibitory Concentration 50; Mice; Neoplasm Transplantation; Quinolones; Structure-Activity Relationship | 2009 |
Slow binding inhibition and mechanism of resistance of non-nucleoside polymerase inhibitors of hepatitis C virus.
Topics: Antiviral Agents; Base Sequence; Benzimidazoles; Benzofurans; Crystallography, X-Ray; DNA, Viral; Hepacivirus; Kinetics; Models, Molecular; Oligoribonucleotides; Protein Conformation; Recombinant Proteins; RNA, Viral; Viral Nonstructural Proteins | 2009 |
Hydrogen transfer from supercritical methanol over a solid base catalyst: a model for lignin depolymerization.
Topics: Benzofurans; Catalysis; Hydrogen; Lignin; Methanol | 2009 |
Convenient synthesis and antimicrobial evaluation of some novel 2-substituted-3-methylbenzofuran derivatives.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Bacteria; Benzofurans; Crystallography, X-Ray; Fungi; Microbial Sensitivity Tests; Models, Molecular; Pyrazoles | 2009 |
Total synthesis of the antibiotic kendomycin by macrocyclization using photo-Fries rearrangement and ring-closing metathesis.
Topics: Aldehydes; Anti-Bacterial Agents; Benzofurans; Carboxylic Acids; Cyclization; Rifabutin | 2009 |
Highly potent naphthofuran-based retinoic acid receptor agonists.
Topics: Benzofurans; Cell Line, Tumor; HeLa Cells; Humans; Protein Isoforms; Receptors, Retinoic Acid; Transcription, Genetic | 2009 |
First steps in the direction of synthetic, allosteric, direct inhibitors of thrombin and factor Xa.
Topics: Allosteric Site; Anticoagulants; Benzofurans; Binding Sites; Chemistry, Pharmaceutical; Drug Design; Factor Xa; Heparin; Humans; Kinetics; Models, Chemical; Polymers; Thrombin | 2009 |
Integrated metabolite and transcript profiling identify a biosynthetic mechanism for hispidol in Medicago truncatula cell cultures.
Topics: Amino Acid Sequence; Benzofurans; Cells, Cultured; Chalcones; Chromatography, High Pressure Liquid; Cloning, Molecular; Gene Expression Profiling; Glucosides; Medicago truncatula; Metabolomics; Molecular Sequence Data; Molecular Structure; Oligonucleotide Array Sequence Analysis; Peroxidases; Recombinant Proteins; RNA, Plant; Substrate Specificity; Triterpenes | 2009 |
Computational insights into the mechanism of ligand unbinding and selectivity of estrogen receptors.
Topics: Benzofurans; Computer Simulation; Estrogen Receptor alpha; Estrogen Receptor beta; Genistein; Ligands; Models, Molecular; Molecular Conformation; Protein Binding; Receptors, Estrogen; Substrate Specificity | 2009 |
Comparison of two vectors for functional expression of a bacterial cytochrome P450 gene in Escherichia coli using CYP153 genes.
Topics: Amino Acid Sequence; Benzofurans; Cell Survival; Cyclohexanes; Cytochrome P-450 Enzyme System; Escherichia coli; Gene Expression; Genes, Bacterial; Genetic Vectors; Molecular Sequence Data; Octanes | 2009 |
Discovery of trans-N-[1-(2-fluorophenyl)-3-pyrazolyl]-3-oxospiro[6-azaisobenzofuran-1(3H),1'-cyclohexane]-4'-carboxamide, a potent and orally active neuropeptide Y Y5 receptor antagonist.
Topics: Administration, Oral; Amides; Animals; ATP-Binding Cassette Transporters; Benzofurans; Brain; Cerebrospinal Fluid; Drug Stability; Eating; Rats; Receptors, Neuropeptide Y; Spiro Compounds | 2009 |
Synthesis and antiprotozoal properties of pentamidine congeners bearing the benzofuran motif.
Topics: Animals; Antiprotozoal Agents; Benzofurans; Cell Line; Leishmania donovani; Pentamidine; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense | 2009 |
Novel benzofuran derivatives with dual 5-HT1A receptor and serotonin transporter affinity.
Topics: Animals; Benzofurans; CHO Cells; Cricetinae; Cricetulus; Humans; Protein Binding; Receptor, Serotonin, 5-HT1A; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship | 2010 |
Improved synthesis of the two-photon caging group 3-nitro-2-ethyldibenzofuran and its application to a caged thymidine phosphoramidite.
Topics: Benzofurans; DNA; Organophosphorus Compounds; Photons; Thymidine Monophosphate | 2010 |
A novel 3-arylcoumarin and three new 2-arylbenzofurans from Mucuna birdwoodiana.
Topics: Benzofurans; Coumarins; Molecular Structure; Mucuna; Plant Stems | 2010 |
Facile synthesis of indole- or benzofuran-fused benzo[a]carbazole-1,4-diones using a tandem two-step reaction sequence.
Topics: Benzofurans; Carbazoles; Catalysis; Cyclization; Indoles | 2011 |
Novel antiviral benzofuran-transition metal complexes.
Topics: Antiviral Agents; Benzofurans; Drug Design; Hep G2 Cells; Hepacivirus; HIV; HIV Reverse Transcriptase; Humans; Hydroxides; Lethal Dose 50; Ligands; Models, Molecular; Nitrogen; Organometallic Compounds; Oxidation-Reduction; Protease Inhibitors; Protein Conformation; Reverse Transcriptase Inhibitors; Spectrum Analysis; Transition Elements | 2010 |
Five new 2-arylbenzofuran derivatives from Morus wittiorum.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Benzofurans; Glucuronidase; Leukocytes; Lipid Peroxidation; Microsomes, Liver; Molecular Structure; Morus; Plant Bark; Rats | 2010 |
Synthesis and characterization of selective dopamine D2 receptor antagonists. 2. Azaindole, benzofuran, and benzothiophene analogs of L-741,626.
Topics: Adenylyl Cyclases; Benzofurans; Cell Line; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Humans; Indoles; Protein Binding; Receptors, Dopamine D2; Thiophenes | 2010 |
Benzofuran-substituted urea derivatives as novel P2Y(1) receptor antagonists.
Topics: Benzofurans; Platelet Activation; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y1; Urea | 2010 |
Design, synthesis, and antitubercular evaluation of novel series of 3-benzofuran-5-aryl-1-pyrazolyl-pyridylmethanone and 3-benzofuran-5-aryl-1-pyrazolylcarbonyl-4-oxo-naphthyridin analogs.
Topics: Animals; Antitubercular Agents; Benzofurans; Chlorocebus aethiops; Drug Design; Drug Resistance, Multiple; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Structure-Activity Relationship; Vero Cells | 2010 |
Hydroxyterphenylphoshine-palladium catalyst for benzo[b]furan synthesis from 2-chlorophenols. bifunctional ligand strategy for cross-coupling of chloroarenes.
Topics: Benzofurans; Catalysis; Chlorophenols; Magnetic Resonance Spectroscopy; Palladium | 2010 |
A novel 18F-labeled pyridyl benzofuran derivative for imaging of β-amyloid plaques in Alzheimer's brains.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Autopsy; Autoradiography; Benzofurans; Brain; Fluorine Radioisotopes; Humans; Male; Mice; Mice, Transgenic; Plaque, Amyloid; Positron-Emission Tomography; Radiopharmaceuticals | 2010 |
Synthesis of benzofuran, benzothiophene, and benzothiazole-based thioamides and their evaluation as K(ATP) channel openers.
Topics: Animals; Benzofurans; Benzothiazoles; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; HEK293 Cells; Humans; KATP Channels; Molecular Conformation; Potassium Channels, Inwardly Rectifying; Structure-Activity Relationship; Thioamides; Thiophenes | 2010 |
Copper catalysis in the construction of indole and benzo[b]furan rings.
Topics: Benzofurans; Catalysis; Copper; Indoles; Ligands | 2011 |
Tandem Blaise-Nenitzescu reaction: one-pot synthesis of 5-hydroxy-α-(aminomethylene)benzofuran-2(3H)-ones from nitriles.
Topics: Amines; Benzofurans; Hydroxylation; Molecular Structure; Nitriles | 2011 |
Indium triflate-catalyzed coupling between nitroalkenes and phenol/naphthols: a simple and direct synthesis of arenofurans by a cyclization reaction.
Topics: Alkenes; Benzofurans; Catalysis; Cyclization; Furans; Mesylates; Naphthols; Phenol | 2011 |
Laccase-catalyzed phenol oxidation. Rapid assignment of ring-proton deficient polycyclic benzofuran regioisomers by experimental 1H-13C long-range coupling constants and DFT-predicted product formation.
Topics: Benzofurans; Biocatalysis; Fourier Analysis; Laccase; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction; Phenols; Protons; Stereoisomerism; Time Factors; Trametes | 2011 |
Structural feature study of benzofuran derivatives as farnesyltransferase inhibitors.
Topics: Benzofurans; Enzyme Inhibitors; Farnesyltranstransferase; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship | 2011 |
Highly cis-selective Rh(I)-catalyzed cyclopropanation reactions.
Topics: Alkenes; Anti-Infective Agents; Antineoplastic Agents; Benzofurans; Catalysis; Cyclization; Cyclopentanes; Cyclopropanes; Diazonium Compounds; Models, Molecular; Molecular Structure; Rhodium; Solvents; Stereoisomerism; Temperature | 2011 |
Silver-catalyzed synthesis of 4-substituted benzofurans via a cascade oxidative coupling-annulation protocol.
Topics: Benzofurans; Catalysis; Oxidation-Reduction; Phenols; Silver | 2011 |
Palladium-catalyzed oxidative cyclization of 3-phenoxyacrylates: an approach to construct substituted benzofurans from phenols.
Topics: Acrylates; Benzofurans; Catalysis; Cyclization; Oxidation-Reduction; Palladium; Phenols | 2011 |
Gold(I)-catalyzed formation of benzo[b]furans from 3-silyloxy-1,5-enynes.
Topics: Alkynes; Benzofurans; Catalysis; Crystallography, X-Ray; Cyclization; Gold; Methane; Molecular Conformation; Silanes | 2011 |
Enantioselective base-free electrophilic amination of benzofuran-2(3H)-ones: catalysis by binol-derived P-spiro quaternary phosphonium salts.
Topics: Amination; Benzofurans; Catalysis; Crystallography, X-Ray; Molecular Conformation; Naphthols; Organophosphorus Compounds; Stereoisomerism | 2011 |
Synthesis and evaluation of benzofuran-2-yl(phenyl)methanone derivatives as ligands for β-amyloid plaques.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Autoradiography; Benzofurans; Brain; Iodine Radioisotopes; Ligands; Mice; Peptide Fragments; Plaque, Amyloid; Protein Binding; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution | 2011 |
Discovery of a novel series of nonacidic benzofuran EP1 receptor antagonists.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Cell Line; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Pain; Rats; Receptors, Prostaglandin E, EP1 Subtype; Structure-Activity Relationship | 2011 |
Alternative spiroketalization methods toward purpuromycin: a diketone approach to prevent benzofuran formation.
Topics: Benzofurans; Cyclization; Furans; Ketones; Molecular Structure; Naphthoquinones; Oxidation-Reduction; Spiro Compounds | 2011 |
Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase.
Topics: Amidohydrolases; Animals; Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Hydroxamic Acids; Metalloproteases; Mice; Mice, Nude; Neoplasms; Structure-Activity Relationship; Transplantation, Heterologous | 2011 |
Asymmetric synthesis of bioactive hydrodibenzofuran alkaloids: (-)-lycoramine, (-)-galanthamine, and (+)-lunarine.
Topics: Alkaloids; Amaryllidaceae Alkaloids; Benzofurans; Brassicaceae; Carbon; Catalysis; Cyclization; Galantamine; Liliaceae; Spermidine; Stereoisomerism | 2011 |
Identification of novel CK2 inhibitors with a benzofuran scaffold by novel non-radiometric in vitro assays.
Topics: Amino Acid Sequence; Animals; Benzofurans; Biological Assay; Casein Kinase II; Drug Evaluation, Preclinical; Electrophoresis, Capillary; Fluorescence Resonance Energy Transfer; Holoenzymes; Humans; Molecular Sequence Data; Peptides; Protein Kinase Inhibitors; Radiometry; Recombinant Proteins; Substrate Specificity; Sus scrofa | 2011 |
Inhibitory effects of constituents from Morus alba var. multicaulis on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Benzofurans; Cell Differentiation; Cell Line; Flavonoids; Macrophages; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Morus; Nitric Oxide; Plant Extracts | 2011 |
Synthesis and antitumor molecular mechanism of agents based on amino 2-(3',4',5'-trimethoxybenzoyl)benzo[b]furan: inhibition of tubulin and induction of apoptosis.
Topics: Animals; Anisoles; Antineoplastic Agents; Apoptosis; Benzofurans; Binding Sites; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Colchicine; Humans; Mice; Neoplasms; Tubulin; Tubulin Modulators | 2011 |
A new benzofuran glucoside from Ficus tikoua Bur.
Topics: Antioxidants; Benzofurans; Ficus; Free Radicals; Glucosides; Nuclear Magnetic Resonance, Biomolecular; Plant Extracts | 2011 |
Breakthrough in concentration quenching threshold of upconversion luminescence via spatial separation of the emitter doping area for bio-applications.
Topics: Benzofurans; Erbium; Fluorescence Resonance Energy Transfer; Fluorides; Nanoparticles; Spectrometry, Fluorescence; Yttrium | 2011 |
Molecular determinants of ivermectin sensitivity at the glycine receptor chloride channel.
Topics: Animals; Antiparasitic Agents; Benzofurans; Caenorhabditis elegans; Chloride Channels; Crystallography, X-Ray; Cysteine; Electrophysiology; Glycine; Hydrogen Bonding; Ivermectin; Mutagenesis, Site-Directed; Mutation; Receptors, Glycine | 2011 |
Synthesis of 2-(polyfluoroaryl)benzofurans via a copper(I)-catalyzed reaction of 2-(2,2-dibromovinyl)phenol with polyfluoroarene.
Topics: Benzofurans; Bromine; Catalysis; Copper; Fluorine; Molecular Structure; Phenol; Vinyl Compounds | 2012 |
Synthesis of (±)-8-deisopropyladunctin B.
Topics: Benzofurans; Dicarboxylic Acids; Piper; Plant Leaves; Pyrans; Stereoisomerism; Sulfonium Compounds | 2012 |
Synthesis and photophysical properties of metallophthalocyanines substituted with a benzofuran based fluoroprobe.
Topics: Benzofurans; Cobalt; Copper; Fluorescent Dyes; Indoles; Isoindoles; Manganese; Metals; Spectrometry, Fluorescence; Zinc | 2012 |
Modification by ferrocene: An approach to enhance antioxidant ability of ailanthoidol to protect DNA.
Topics: Amidines; Antioxidants; Benzofurans; DNA; Ferrous Compounds; Free Radical Scavengers; Kinetics; Metallocenes; Oxidation-Reduction | 2012 |
Synthesis of benzofuran based 1,3,5-substituted pyrazole derivatives: as a new class of potent antioxidants and antimicrobials--a novel accost to amend biocompatibility.
Topics: Anti-Infective Agents; Antioxidants; Benzofurans; Biocompatible Materials; Microbial Viability; Molecular Structure; Pyrazoles; Structure-Activity Relationship | 2012 |
A new benzofuran derivative from Flemingia philippinensis Merr. et Rolfe.
Topics: Benzofurans; Fabaceae; Magnetic Resonance Spectroscopy | 2012 |
Novel 5-substituted benzyloxy-2-arylbenzofuran-3-carboxylic acids as calcium activated chloride channel inhibitors.
Topics: Animals; Anoctamin-1; Benzofurans; Calcium; Carboxylic Acids; Cell Line; Chloride Channels; Humans; Membrane Potentials; Neoplasm Proteins; Rats; Structure-Activity Relationship | 2012 |
A photochemical route to 2-substituted benzo[b]furans.
Topics: Benzofurans; Molecular Structure; Photochemical Processes; Quantum Theory | 2012 |
Pyridofuran substituted pyrimidine derivatives as HCV replication (replicase) inhibitors.
Topics: Animals; Antiviral Agents; Benzofurans; Enzyme Inhibitors; Furans; Half-Life; Hepacivirus; Liver; Pyrimidine Nucleosides; Pyrimidines; Rats; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Virus Replication | 2012 |
Toluene dioxygenase-catalyzed cis-dihydroxylation of benzo[b]thiophenes and benzo[b]furans: synthesis of benzo[b]thiophene 2,3-oxide.
Topics: Benzofurans; Biocatalysis; Crystallography, X-Ray; Hydroxylation; Models, Molecular; Molecular Structure; Oxygenases; Stereoisomerism; Thiophenes | 2012 |
Comprehensive mass flow analysis of Swedish sludge contaminants.
Topics: Benzofurans; Dioxins; Environmental Monitoring; Halogenated Diphenyl Ethers; Household Products; Metals; Pesticides; Sewage; Sweden; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Pollution, Chemical | 2013 |
Synthesis and biological evaluation of novel heterocyclic derivatives of combretastatin A-4.
Topics: Antimitotic Agents; Benzofurans; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colchicine; Heterocyclic Compounds; Humans; Indoles; Microscopy, Confocal; Microtubules; Stereoisomerism; Stilbenes; Thiophenes | 2012 |
Synthesis and structural characterization of new Cu(I) complexes with the antithyroid drug 6-n-propyl-thiouracil. study of the Cu(I)-catalyzed intermolecular cycloaddition of iodonium ylides toward benzo[b]furans with pharmaceutical implementations.
Topics: Antithyroid Agents; Benzofurans; Catalysis; Copper; Crystallography, X-Ray; Cyclization; Iodides; Iodine; Models, Molecular; Molecular Structure; Organometallic Compounds; Pharmaceutical Preparations; Quantum Theory; Thiourea | 2012 |
Benzofuran and indole synthesis via Cu(I)-catalyzed coupling of N-tosylhydrazone and o-hydroxy or o-amino phenylacetylene.
Topics: Acetylene; Benzofurans; Catalysis; Copper; Hydrazones; Indoles; Molecular Structure | 2013 |
Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase.
Topics: Animals; Benzofurans; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Inhibitory Concentration 50; Mice; Molecular Structure; Rats; Rats, Sprague-Dawley | 2013 |
Highly diastereoselective multicomponent cascade reactions: efficient synthesis of functionalized 1-indanols.
Topics: Alcohols; Aldehydes; Benzofurans; Catalysis; Crystallography, X-Ray; Molecular Conformation; Oxygen; Stereoisomerism | 2013 |
Potent BRAF kinase inhibitors based on 2,4,5-trisubstituted imidazole with naphthyl and benzothiophene 4-substituents.
Topics: Benzofurans; Cell Line, Tumor; Cell Survival; Humans; Imidazoles; Melanoma; Naphthols; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Structure-Activity Relationship; Thiophenes | 2013 |
Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6'-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors.
Topics: Benzofurans; Drug Discovery; Humans; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Conformation; Stereoisomerism; Structure-Activity Relationship | 2013 |
Identification of benzofurano[3,2-d]pyrimidin-2-ones, a new series of HIV-1 nucleotide-competing reverse transcriptase inhibitors.
Topics: Animals; Benzofurans; HIV Reverse Transcriptase; HIV-1; Humans; Microsomes, Liver; Nucleotides; Protein Binding; Pyrimidinones; Rats; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2013 |
Comparable strength of OH-O versus OH-π hydrogen bonds in hydrogen-bonded 2,3-benzofuran clusters with water and methanol.
Topics: Benzofurans; Electrons; Hydrogen Bonding; Methanol; Models, Molecular; Oxygen; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Water | 2013 |
Nucleotide competing reverse transcriptase inhibitors: discovery of a series of non-basic benzofurano[3,2-d]pyrimidin-2-one derived inhibitors.
Topics: Benzofurans; Caco-2 Cells; Cell Membrane Permeability; HIV Reverse Transcriptase; HIV-1; Humans; Microsomes, Liver; Nucleotides; Protein Binding; Pyrimidinones; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship | 2013 |
Palladium-catalyzed addition of potassium aryltrifluoroborates to aliphatic nitriles: synthesis of alkyl aryl ketones, diketone compounds, and 2-arylbenzo[b]furans.
Topics: Benzofurans; Borates; Catalysis; Ketones; Molecular Structure; Nitriles; Organometallic Compounds; Palladium; Potassium | 2013 |
Designing allosteric regulators of thrombin. Exosite 2 features multiple subsites that can be targeted by sulfated small molecules for inducing inhibition.
Topics: Allosteric Regulation; Benzofurans; Binding Sites; Blood Coagulation; Dimerization; Drug Design; Humans; Kinetics; Models, Molecular; Protein Conformation; Serine Proteinase Inhibitors; Substrate Specificity; Sulfates; Thrombin | 2013 |
Design of a highly selective and potent class of non-planar estrogen receptor β agonists.
Topics: Benzofurans; Crystallography, X-Ray; Cyclohexanes; Drug Design; Estrogen Receptor alpha; Estrogen Receptor beta; Heterocyclic Compounds, 3-Ring; Molecular Conformation; Phenols; Protein Binding; Stereoisomerism; Structure-Activity Relationship | 2013 |
Synthesis of (Z)-2-((1H-indazol-3-yl)methylene)-6-[¹¹C]methoxy-7-(piperazin-1-ylmethyl)benzofuran-3(2H)-one as a new potential PET probe for imaging of the enzyme PIM1.
Topics: Animals; Benzofurans; Carbon Isotopes; Fungal Proteins; Humans; Indazoles; Mice; Mitogen-Activated Protein Kinases; Neoplasms; Piperazines; Positron-Emission Tomography; Protein Kinase Inhibitors; Radiopharmaceuticals | 2013 |
Synthesis and cytotoxic activities of novel hybrid 2-phenyl-3-alkylbenzofuran and imidazole/triazole compounds.
Topics: Antineoplastic Agents; Benzofurans; Binding Sites; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Imidazoles; MCF-7 Cells; Molecular Docking Simulation; Phosphatidylinositol 3-Kinases; Protein Structure, Tertiary; Structure-Activity Relationship; Triazoles | 2013 |
3-Acyl-5-hydroxybenzofuran derivatives as potential anti-estrogen breast cancer agents: a combined experimental and theoretical investigation.
Topics: Antineoplastic Agents, Hormonal; Benzofurans; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Estrogen Receptor alpha; Female; Humans; Hydroxylation; MCF-7 Cells; Molecular Structure; Quantum Theory | 2013 |
Experimental rayless goldenrod (Isocoma pluriflora) toxicosis in horses.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Asteraceae; Benzofurans; Cardiomyopathies; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Histological Techniques; Horses; Ketones; Plant Poisoning; Southwestern United States; Troponin I | 2013 |
Exploring the potential of diarylacetylenediols as hydrogen bonding catalysts.
Topics: Acetylene; Benzofurans; Catalysis; Cyclization; Hydrogen Bonding; Molecular Structure; Phenols | 2013 |
Synthesis of polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.
Topics: Acylation; Antiprotozoal Agents; Benzofurans; Cyclization; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanosoma brucei brucei | 2013 |
Synthetic models related to methoxalen and menthofuran-cytochrome P450 (CYP) 2A6 interactions. benzofuran and coumarin derivatives as potent and selective inhibitors of CYP2A6.
Topics: Aryl Hydrocarbon Hydroxylases; Benzofurans; Coumarins; Cytochrome P-450 CYP2A6; Enzyme Inhibitors; Humans; Models, Chemical; Monoterpenes; Protein Binding | 2013 |
One-pot synthesis, FT-IR and density functional method (DFT) studies on N-benzyl-N-ethyl-N-[5-nitro-2-(1,1,3,3-Tetramethylbutylamino)-1-benzofuran-3-yl]amine.
Topics: Amines; Benzene Derivatives; Benzofurans; Magnetic Resonance Spectroscopy; Methylation; Models, Molecular; Nitro Compounds; Quantum Theory; Spectroscopy, Fourier Transform Infrared | 2013 |
Benzofurazane as a new redox label for electrochemical detection of DNA: towards multipotential redox coding of DNA bases.
Topics: Benzofurans; DNA; DNA-Directed DNA Polymerase; Electrochemical Techniques; Nucleosides; Oxidation-Reduction | 2013 |
One-pot synthesis of substituted benzo[b]furans from mono- and dichlorophenols using palladium catalysts bearing dihydroxyterphenylphosphine.
Topics: Benzofurans; Catalysis; Chlorophenols; Molecular Structure; Organometallic Compounds; Organophosphorus Compounds; Palladium | 2013 |
Design, synthesis and antitubercular evaluation of novel 2-substituted-3H-benzofuro benzofurans via palladium-copper catalysed Sonagashira coupling reaction.
Topics: Animals; Antitubercular Agents; Benzofurans; Catalysis; Copper; Drug Design; Heterocyclic Compounds, 4 or More Rings; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Palladium; Structure-Activity Relationship | 2013 |
Hybrid benzofuran-bisindole derivatives: new prototypes with promising anti-hyperlipidemic activities.
Topics: Animals; Antioxidants; Benzofurans; Cholesterol; Enzyme Activation; Hypolipidemic Agents; Indoles; Lipolysis; Male; Molecular Structure; Phosphatidylcholine-Sterol O-Acyltransferase; Phospholipids; Rats; Triglycerides | 2013 |
A three-dimensional chemical phase pharmacophore mapping, QSAR modelling and electronic feature analysis of benzofuran salicylic acid derivatives as LYP inhibitors.
Topics: Benzofurans; Enzyme Inhibitors; Humans; Hydrogen Bonding; Models, Molecular; Protein Tyrosine Phosphatase, Non-Receptor Type 22; Quantitative Structure-Activity Relationship; Reproducibility of Results; Salicylic Acid; Static Electricity | 2013 |
Synthesis of novel benzo-fused heteroaryl derivatives as Ca²⁺/calmodulin-dependent protein kinase II inhibitors.
Topics: Benzofurans; Benzothiazoles; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Indoles; Protein Binding; Protein Kinase Inhibitors; Structure-Activity Relationship | 2013 |
Synthesis and antiproliferative activity of benzofuran-based analogs of cercosporamide against non-small cell lung cancer cell lines.
Topics: Antineoplastic Agents; Benzofurans; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Molecular Structure; Structure-Activity Relationship | 2013 |
Characterization of telmisartan-derived PPARγ agonists: importance of moiety shift from position 6 to 5 on potency, efficacy and cofactor recruitment.
Topics: 3T3-L1 Cells; Animals; Benzimidazoles; Benzoates; Benzofurans; Chlorocebus aethiops; COS Cells; Diabetes Mellitus, Type 2; Humans; Ligands; Mice; PPAR gamma; Structure-Activity Relationship; Telmisartan; Thiophenes | 2012 |
Synthesis and anti-TMV activity of dialkyl/dibenzyl 2-((6-substituted-benzo[d]thiazol-2-ylamino)(benzofuran-2-yl)methyl) malonates.
Topics: Antiviral Agents; Benzofurans; Benzothiazoles; Malonates; Microbial Sensitivity Tests; Molecular Structure; Tobacco Mosaic Virus | 2013 |
Synthesis and biological evaluation of benzo[b]furans as inhibitors of tubulin polymerization and inducers of apoptosis.
Topics: Apoptosis; bcl-2-Associated X Protein; Benzofurans; Binding Sites; Caspase 3; Cell Line, Tumor; DNA Fragmentation; Humans; Molecular Docking Simulation; Polymerization; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2014 |
Bioactive benzofuran neolignans from Aristolochia fordiana.
Topics: Animals; Aristolochia; Benzofurans; Cell Line; Cell Line, Tumor; Cell Survival; Humans; Inhibitory Concentration 50; Lignans; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; Nitric Oxide; Plant Extracts; Plants, Medicinal | 2013 |
Benzofuran derivatives from alkynyl-substituted benzynes and aryl halides.
Topics: Alkynes; Benzene Derivatives; Benzofurans; Catalysis; Hydrocarbons, Halogenated; Models, Molecular; Molecular Structure; Organometallic Compounds; Palladium | 2014 |
Chemoenzymatic total syntheses of ribisins A, B, and D, polyoxygenated benzofuran derivatives displaying NGF-potentiating properties.
Topics: Benzofurans; Biological Products; Catechols; Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Molecular Structure; Nerve Growth Factor; Stereoisomerism | 2014 |
Direct synthesis of benzofuro[2,3-b]pyrroles through a radical addition/[3,3]-sigmatropic rearrangement/cyclization/lactamization cascade.
Topics: Benzofurans; Cyclization; Free Radicals; Oximes; Pyrroles; Pyrrolidines; Stereoisomerism | 2014 |
Highly diastereo- and enantioselective Michael addition of 3-substituted benzofuran-2(3H)-ones to 4-oxo-enoates catalyzed by lanthanide(III) complexes.
Topics: Benzofurans; Catalysis; Coordination Complexes; Lanthanum; Stereoisomerism | 2014 |
The structural diversity of benzofuran resorcinarene leads to enhanced fluorescence.
Topics: Benzofurans; Calixarenes; Chemistry Techniques, Synthetic; Crystallography, X-Ray; Fluorescence; Molecular Conformation; Molecular Structure; Phenylalanine; Spectrometry, Fluorescence; Structure-Activity Relationship | 2014 |
Synthesis of benzofuro[6,7-d]thiazoles, benzofuro[7,6-d]thiazoles and 6-arylaminobenzo[d]thiazole-4,7-diones as antifungal agent.
Topics: Antifungal Agents; Aspergillus; Benzofurans; Candida; Cryptococcus neoformans; Microbial Sensitivity Tests; Thiazoles | 2014 |
The mechanism of allosteric inhibition of protein tyrosine phosphatase 1B.
Topics: Allosteric Site; Benzofurans; Catalytic Domain; Drug Design; Molecular Dynamics Simulation; Mutation; Principal Component Analysis; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Signal Transduction | 2014 |
Benzofuran derivatives as anticancer inhibitors of mTOR signaling.
Topics: Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HCT116 Cells; HT29 Cells; Humans; Molecular Structure; Signal Transduction; Structure-Activity Relationship; TOR Serine-Threonine Kinases | 2014 |
Hydrogen sulfide deactivates common nitrobenzofurazan-based fluorescent thiol labeling reagents.
Topics: Benzofurans; Fluorescent Dyes; Hydrogen Sulfide; Indicators and Reagents; Sulfhydryl Compounds | 2014 |
Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Chloride Channels; Drug Delivery Systems; HEK293 Cells; Humans; Kidney; Niflumic Acid; Oocytes; Species Specificity; Xenopus laevis | 2014 |
A fast entry to furanoditerpenoid-based Hedgehog signaling inhibitors: identifying essential structural features.
Topics: Acacia; Benzofurans; Hedgehog Proteins; Molecular Structure; Signal Transduction; Structure-Activity Relationship; Terpenes | 2014 |
Coumestan inhibits radical-induced oxidation of DNA: is hydroxyl a necessary functional group?
Topics: Amidines; Antioxidants; Benzofurans; Biphenyl Compounds; Coumarins; DNA; Glutathione; Hydroxyl Radical; Oxidation-Reduction; Picrates | 2014 |
Discovery of a benzofuran derivative (MBPTA) as a novel ROCK inhibitor that protects against MPP⁺-induced oxidative stress and cell death in SH-SY5Y cells.
Topics: Acetamides; Alkanesulfonic Acids; Antioxidants; Benzofurans; Cell Death; Cell Line, Tumor; Cytoprotection; Drug Discovery; Humans; Membrane Potential, Mitochondrial; Molecular Targeted Therapy; Oncogene Protein v-akt; Oxidants; Oxidative Stress; Parkinson Disease; Phosphatidylinositol 3-Kinases; Pyridinium Compounds; rho-Associated Kinases; Signal Transduction; Thiadiazoles | 2014 |
A base-modified PNA-graphene oxide platform as a turn-on fluorescence sensor for the detection of human telomeric repeats.
Topics: Base Sequence; Benzofurans; Graphite; Humans; Nucleic Acid Hybridization; Oxides; Peptide Nucleic Acids; Spectrometry, Fluorescence; Telomere; Uracil | 2014 |
Photocatalytic synthesis of dihydrobenzofurans by oxidative [3+2] cycloaddition of phenols.
Topics: Alkenes; Benzofurans; Biological Products; Catalysis; Cycloaddition Reaction; Light; Oxidation-Reduction; Phenols; Ruthenium | 2014 |
A (68)Ga complex based on benzofuran scaffold for the detection of β-amyloid plaques.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzofurans; Disease Models, Animal; Gallium Radioisotopes; Mice; Mice, Transgenic; Molecular Imaging; Organometallic Compounds; Peptide Fragments; Plaque, Amyloid; Positron-Emission Tomography; Radiopharmaceuticals | 2014 |
Benzofuran-chalcone hybrids as potential multifunctional agents against Alzheimer's disease: synthesis and in vivo studies with transgenic Caenorhabditis elegans.
Topics: Acetylcholine; Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Antioxidants; Benzofurans; Binding Sites; Caenorhabditis elegans; Chalcone; Chalcones; Crystallography, X-Ray; Disease Models, Animal; Humans; Microscopy, Fluorescence; Molecular Conformation; Molecular Docking Simulation; Oxidative Stress; Protein Structure, Tertiary; Structure-Activity Relationship; Thiophenes | 2014 |
Orthogonal selectivity with cinnamic acids in 3-substituted benzofuran synthesis through C-H olefination of phenols.
Topics: Alkenes; Benzofurans; Catalysis; Cinnamates; Kinetics; Molecular Structure; Organometallic Compounds; Palladium; Phenols | 2015 |
Chiral recognition with a benzofuran receptor that mimics an oxyanion hole.
Topics: Anions; Benzofurans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Stereoisomerism | 2015 |
Enantioselective synthesis of (-)-maoecrystal V by enantiodetermining C-H functionalization.
Topics: Antineoplastic Agents; Benzofurans; Carbon; Catalysis; Cell Line, Tumor; Cell Proliferation; Cycloaddition Reaction; Diterpenes; Humans; Hydrogen; Rhodium; Stereoisomerism; Substrate Specificity | 2014 |
An efficient synthesis and biological screening of benzofuran and benzo[d]isothiazole derivatives for Mycobacterium tuberculosis DNA GyrB inhibition.
Topics: Animals; Antitubercular Agents; Benzofurans; Benzothiazoles; Cell Line; DNA Gyrase; Dose-Response Relationship, Drug; Humans; Macrophages; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Piperazines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2014 |
Flavonoids and arylbenzofurans from the rhizomes and roots of Sophora tonkinensis with IL-6 production inhibitory activity.
Topics: Benzofurans; Calcimycin; Cell Line; Flavanones; Flavonoids; Humans; Interleukin-6; Magnetic Resonance Spectroscopy; Mast Cells; Molecular Conformation; Plant Extracts; Plant Roots; Rhizome; Sophora; Terpenes; Tetradecanoylphorbol Acetate | 2014 |
Controlling the fluorescence of benzofuran-modified uracil residues in oligonucleotides by triple-helix formation.
Topics: Base Sequence; Benzofurans; Deoxyuridine; DNA; DNA, Single-Stranded; Fluorescent Dyes; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; RNA; Spectrometry, Fluorescence; Uracil | 2015 |
Benzofuran analogues of amphetamine and methamphetamine: studies on the metabolism and toxicological analysis of 5-APB and 5-MAPB in urine and plasma using GC-MS and LC-(HR)-MS(n) techniques.
Topics: Amphetamine; Animals; Benzofurans; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Humans; Male; Mass Spectrometry; Methamphetamine; Rats; Rats, Wistar | 2015 |
Synthesis and cytotoxic properties of halogen and aryl-/heteroarylpiperazinyl derivatives of benzofurans.
Topics: Apoptosis; Benzofurans; Cell Line; Cell Line, Tumor; Halogens; HeLa Cells; HL-60 Cells; Human Umbilical Vein Endothelial Cells; Humans; K562 Cells; Structure-Activity Relationship | 2015 |
Acetylcholinesterase in zebrafish embryos as a tool to identify neurotoxic effects in sediments.
Topics: Acetylcholinesterase; Animals; Benzofurans; Chlorpyrifos; Cholinesterase Inhibitors; Embryo, Nonmammalian; Geologic Sediments; Inhibitory Concentration 50; Paraoxon; Polycyclic Aromatic Hydrocarbons; Toxicity Tests, Acute; Water Pollutants, Chemical; Zebrafish; Zebrafish Proteins | 2015 |
Fluorination of 2-substituted benzo[b]furans with Selectfluor™.
Topics: Benzofurans; Diazonium Compounds; Hydrocarbons, Fluorinated; Molecular Structure | 2015 |
Antioxidant activity and inhibition of α-glucosidase by hydroxyl-functionalized 2-arylbenzo[b]furans.
Topics: alpha-Glucosidases; Antioxidants; Benzofurans; Catalytic Domain; Glycoside Hydrolase Inhibitors; Hydroxides; Molecular Docking Simulation; Saccharomyces cerevisiae; Structure-Activity Relationship | 2015 |
Synthesis and biological activity of novel mono-indole and mono-benzofuran inhibitors of bacterial transcription initiation complex formation.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Benzofurans; DNA-Directed RNA Polymerases; Humans; Indoles; Models, Molecular; Structure-Activity Relationship; Transcriptional Activation | 2015 |
One-pot synthesis of 2,3-disubstituted dihydrobenzofurans and benzofurans via rhodium-catalyzed intramolecular C-H insertion reaction.
Topics: Benzofurans; Carbon; Catalysis; Chemistry Techniques, Synthetic; Hydrogen; Rhodium | 2015 |
FT-IR, FT-Raman, UV/Vis spectra and fluorescence imaging studies on 2-(bromoacetyl)benzo(b)furan by ab initio DFT calculations.
Topics: Acetylation; Benzofurans; Halogenation; Models, Molecular; Optical Imaging; Quantum Theory; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2015 |
Synthesis of a novel class of substituted benzothiophene or benzofuran derivatives as BMP-2 up-regulators and evaluation of the BMP-2-up-regulating effects in vitro and the effects on glucocorticoid-induced osteoporosis in rats.
Topics: Animals; Benzofurans; Bone Morphogenetic Protein 2; Cell Line; Female; Glucocorticoids; Male; Mice; Mice, Inbred Strains; Osteoporosis; Rats; Rats, Wistar; Thiophenes; Up-Regulation | 2015 |
Eco-friendly solvents for palladium-catalyzed desulfitative C-H bond arylation of heteroarenes.
Topics: Benzofurans; Catalysis; Diethyl Pyrocarbonate; Ethers; Indoles; Palladium; Pyrroles; Solvents; Sulfones; Thiophenes | 2015 |
High Cytotoxicity and Apoptotic Effects of Natural Bioactive Benzofuran Derivative on the MCF-7 Breast Cancer Cell Line.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzofurans; Biological Products; Breast Neoplasms; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Molecular Structure; Petasites; Plant Roots; Structure-Activity Relationship | 2015 |
Design, synthesis, and biological evaluation of benzofuran- and 2,3-dihydrobenzofuran-2-carboxylic acid N-(substituted)phenylamide derivatives as anticancer agents and inhibitors of NF-κB.
Topics: Amides; Animals; Antineoplastic Agents; Benzofurans; Carboxylic Acids; Cell Line; Cell Survival; Drug Design; Drug Screening Assays, Antitumor; Humans; Lipopolysaccharides; Mice; NF-kappa B; Protein Binding; Signal Transduction; Structure-Activity Relationship | 2015 |
Heteroaromatic analogs of the resveratrol analog DMU-212 as potent anti-cancer agents.
Topics: Antineoplastic Agents; Benzofurans; Benzothiazoles; Binding Sites; Cell Line, Tumor; Cell Survival; Colchicine; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Protein Structure, Tertiary; Resveratrol; Stilbenes; Thiophenes; Tubulin | 2015 |
Liquid chromatography-quadrupole time-of-flight mass spectrometry for screening in vitro drug metabolites in humans: investigation on seven phenethylamine-based designer drugs.
Topics: 3,4-Methylenedioxyamphetamine; Amines; Amphetamines; Benzodioxoles; Benzofurans; Butylamines; Catalysis; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Cytosol; Designer Drugs; Dose-Response Relationship, Drug; Female; Humans; Likelihood Functions; Liver; Male; Mass Spectrometry; Methamphetamine; Microsomes, Liver; Models, Chemical; Phenethylamines; Propylamines; Reproducibility of Results; Substance Abuse Detection; Wastewater; Water Purification | 2015 |
Maternally transferred dioxin-like compounds can affect the reproductive success of European eel.
Topics: Anguilla; Animal Migration; Animals; Benzofurans; Dioxins; Europe; Female; Fresh Water; Larva; Polychlorinated Dibenzodioxins; Reproduction; Risk Assessment; Water Pollutants, Chemical; Zygote | 2016 |
Paeoveitols A-E from Paeonia veitchii.
Topics: Benzofurans; Diterpenes; HEK293 Cells; Humans; Molecular Structure; Monoterpenes; Paeonia; Plant Roots | 2015 |
Synthesis and structure-activity relationship study of benzofuran-based chalconoids bearing benzylpyridinium moiety as potent acetylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Animals; Benzofurans; Chalcones; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Molecular Structure; Pyridinium Compounds; Structure-Activity Relationship | 2015 |
The isolation and synthesis of a novel benzofuran compound from Tephrosia purpurea, and the synthesis of several related derivatives, which suppress histamine H1 receptor gene expression.
Topics: Anti-Allergic Agents; Benzofurans; Gene Expression Regulation; HeLa Cells; Humans; Isomerism; Plant Components, Aerial; Receptors, Histamine H1; Tephrosia | 2015 |
Selective Halogen-Lithium Exchange of 1,2-Dihaloarenes for Successive [2+4] Cycloadditions of Arynes and Isobenzofurans.
Topics: Benzofurans; Bromides; Catalysis; Cycloaddition Reaction; Iodides; Lithium; Polycyclic Compounds | 2015 |
Medium-Ring Effects on the Endo/Exo Selectivity of the Organocatalytic Intramolecular Diels-Alder Reaction.
Topics: Benzofurans; Catalysis; Cycloaddition Reaction; Diterpenes; Molecular Structure; Stereoisomerism | 2015 |
Synthesis and biological evaluation of novel orally available 1-phenyl-6-aminouracils containing dimethyldihydrobenzofuranol structure for the treatment of allergic skin diseases.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Benzofurans; Cell Line, Tumor; Cell Membrane Permeability; Dermatitis, Atopic; Half-Life; Humans; Mice; Microsomes; Pruritus; Rats; Uracil | 2016 |
o-Quinone Methides via Oxone-Mediated Benzofuran Oxidative Dearomatization and Their Intramolecular Cycloaddition with Carbonyl Groups: An Expeditious Construction of the Central Tetracyclic Core of Integrastatins, Epicoccolide A, and Epicocconigrone A.
Topics: Benzofurans; Cycloaddition Reaction; Heterocyclic Compounds, Bridged-Ring; Indolequinones; Molecular Structure; Oxidation-Reduction; Stereoisomerism; Sulfuric Acids | 2016 |
Profilin potentiates chemotherapeutic agents mediated cell death via suppression of NF-κB and upregulation of p53.
Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Doxorubicin; Enzyme Activation; HCT116 Cells; Humans; Neoplasms; NF-KappaB Inhibitor alpha; Paclitaxel; Poly(ADP-ribose) Polymerases; Profilins; Proto-Oncogene Proteins c-mdm2; RNA Interference; RNA, Small Interfering; Transcription Factor RelA; Transcriptional Activation; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Up-Regulation; Vinblastine | 2016 |
Sunlight Irradiation of Highly Brominated Polyphenyl Ethers Generates Polybenzofuran Products That Alter Dioxin-responsive mRNA Expression in Chicken Hepatocytes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Avian Proteins; Benzofurans; Chick Embryo; Chickens; Chromatography, Liquid; Female; Gene Expression Regulation; Halogenated Diphenyl Ethers; Hepatocytes; Ions; Mass Spectrometry; Photolysis; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; RNA, Messenger; Sunlight; Transcription, Genetic | 2016 |
Synthesis of benzofuran derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase: effects on cell toxicity and osteoblast-induced mineralization.
Topics: Alkaline Phosphatase; Animals; Benzofurans; Calcification, Physiologic; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; Mice; Molecular Structure; Osteoclasts; Structure-Activity Relationship; Substrate Specificity | 2016 |
Dioxin distribution characteristics and health risk assessment in different size particles of fly ash from MSWIs in China.
Topics: Benzofurans; China; Coal Ash; Health Status Indicators; Humans; Particle Size; Polychlorinated Dibenzodioxins; Risk Assessment; Solid Waste | 2016 |
Accessing a Biologically Relevant Benzofuran Skeleton by a One-Pot Tandem Heck Alkynylation/Cyclization Reaction Using Well-Defined Palladium N-Heterocyclic Carbene Complexes.
Topics: Alkynes; Benzofurans; Cyclization; Heterocyclic Compounds; Magnetic Resonance Spectroscopy; Methane; Models, Molecular; Palladium; Spectrometry, Mass, Electrospray Ionization | 2016 |
Mitochondria-targeted ruthenium (II) polypyridyl complexes with benzofuran group for live cell imaging.
Topics: Benzofurans; Fluorescent Dyes; HEK293 Cells; HeLa Cells; Humans; Microscopy, Fluorescence; Mitochondria; Ruthenium | 2016 |
2-Phenylbenzofuran derivatives as butyrylcholinesterase inhibitors: Synthesis, biological activity and molecular modeling.
Topics: Benzofurans; Butyrylcholinesterase; Cholinesterase Inhibitors; Models, Molecular | 2016 |
Discovery of Potent Benzofuran-Derived Diapophytoene Desaturase (CrtN) Inhibitors with Enhanced Oral Bioavailability for the Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Bacterial Proteins; Benzofurans; Biological Availability; Drug Discovery; Enzyme Inhibitors; Female; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Oxidoreductases; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Tissue Distribution | 2016 |
Discovery and optimization of new benzofuran derivatives against p53-independent malignant cancer cells through inhibition of HIF-1 pathway.
Topics: Antineoplastic Agents; Benzofurans; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Hypoxia-Inducible Factor 1; MCF-7 Cells; Molecular Structure; Neoplasms; Structure-Activity Relationship; Tumor Suppressor Protein p53 | 2016 |
Benzo[b]furan derivatives induces apoptosis by targeting the PI3K/Akt/mTOR signaling pathway in human breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Breast Neoplasms; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; MCF-7 Cells; Molecular Structure; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Structure-Activity Relationship; TOR Serine-Threonine Kinases | 2016 |
Rational Development of Novel Activity Probes for the Analysis of Human Cytochromes P450.
Topics: Benzofurans; Cytochrome P-450 Enzyme System; Humans; Immunoblotting; Kinetics; Liver; Mass Spectrometry; Molecular Probes; NADP; Protein Binding; Protein Isoforms; Proteomics | 2016 |
Discovery of Benzofuran Derivatives that Collaborate with Insulin-Like Growth Factor 1 (IGF-1) to Promote Neuroprotection.
Topics: Animals; Benzofurans; Cells, Cultured; Dose-Response Relationship, Drug; Drug Discovery; Insulin-Like Growth Factor I; Molecular Structure; Neurons; Neuroprotection; Neuroprotective Agents; Rats; Structure-Activity Relationship | 2016 |
Development of (99m)Tc-Labeled Pyridyl Benzofuran Derivatives To Detect Pancreatic Amylin in Islet Amyloid Model Mice.
Topics: Animals; Benzofurans; Drug Stability; Humans; Islet Amyloid Polypeptide; Isotope Labeling; Male; Mice; Pancreas; Protein Aggregates; Pyridines; Technetium; Tissue Distribution | 2016 |
White snakeroot poisoning in goats: Variations in toxicity with different plant chemotypes.
Topics: Ageratina; Animals; Benzofurans; Dose-Response Relationship, Drug; Female; Goat Diseases; Goats; Plant Extracts; Plant Poisoning; Random Allocation | 2016 |
A novel arylbenzofuran induces cervical cancer cell apoptosis and G1/S arrest through ERK-mediated Cdk2/cyclin-A signaling pathway.
Topics: Animals; Apoptosis; Benzofurans; Cell Line, Tumor; Cyclin A2; Cyclin-Dependent Kinase 2; Female; G1 Phase Cell Cycle Checkpoints; HeLa Cells; Humans; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molecular Structure; Phytotherapy; Plant Extracts; Protein Kinases; Signal Transduction; Tumor Burden; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2016 |
Design, Synthesis and Antifungal Activity of Novel Benzofuran-Triazole Hybrids.
Topics: Benzofurans; Click Chemistry; Drug Design; Fungi; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Triazoles | 2016 |
Design, synthesis and anticancer activity of novel hybrid compounds between benzofuran and N-aryl piperazine.
Topics: Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Piperazine; Piperazines; Structure-Activity Relationship | 2016 |
Effects of ultrasonic processing on degradation of salvianolic acid B in aqueous solution.
Topics: Benzofurans; Chromatography, Liquid; Drug Stability; Hydrogen-Ion Concentration; Solutions; Spectrometry, Mass, Electrospray Ionization; Temperature; Ultrasonics; Water | 2016 |
Variation in toxicity during the biodegradation of various heterocyclic and homocyclic aromatic hydrocarbons in single and multi-substrate systems.
Topics: Benzofurans; Biodegradation, Environmental; Chryseobacterium; Environmental Pollutants; Escherichia coli; Hydrocarbons, Aromatic; Naphthalenes; Oxidoreductases; Pseudomonas fluorescens; Quinolones; Thiophenes | 2017 |
Colletochlorins E and F, New Phytotoxic Tetrasubstituted Pyran-2-one and Dihydrobenzofuran, Isolated from Colletotrichum higginsianum with Potential Herbicidal Activity.
Topics: Animals; Artemia; Benzofurans; Colletotrichum; Herbicides; Heterocyclic Compounds, 4 or More Rings; Molecular Structure; Pyrones; Secondary Metabolism; Solanum lycopersicum; Sonchus | 2017 |
Rational design, synthesis, and evaluation of novel 2,4-Chloro- and Hydroxy-Substituted diphenyl Benzofuro[3,2-b]Pyridines: Non-intercalative catalytic topoisomerase I and II dual inhibitor.
Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Biocatalysis; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Design; Humans; Pyridines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 2017 |
An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-κB.
Topics: Animals; Benzofurans; Cell Line, Tumor; HEK293 Cells; Humans; Iridium; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Prostatic Neoplasms; Random Allocation; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2017 |
In silico identification of potential inhibitors targeting Streptococcus mutans sortase A.
Topics: Aminoacyltransferases; Bacterial Adhesion; Bacterial Proteins; Benzofurans; Biofilms; Computer Simulation; Cysteine Endopeptidases; Dental Caries; Pyrroles; Streptococcus mutans; Thiadiazoles | 2017 |
New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Benzofurans; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Formaldehyde; Lipoxygenase Inhibitors; Male; Molecular Docking Simulation; Molecular Structure; Rats; Rats, Wistar; Rhodanine; Structure-Activity Relationship; Thiophenes | 2017 |
Design, synthesis, and evaluation of benzofuran derivatives as novel anti-pancreatic carcinoma agents via interfering the hypoxia environment by targeting HIF-1α pathway.
Topics: Animals; Antineoplastic Agents; Benzofurans; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Molecular Structure; Neoplasms, Experimental; Pancreatic Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2017 |
Design, synthesis, and biological evaluation of a new class of benzo[b]furan derivatives as antiproliferative agents, with in silico predicted antitubulin activity.
Topics: Antineoplastic Agents; Benzofurans; Binding Sites; Cell Cycle Checkpoints; Cell Proliferation; Colchicine; Drug Design; HeLa Cells; Humans; MCF-7 Cells; Molecular Docking Simulation; Protein Structure, Tertiary; Tubulin; Tubulin Modulators | 2018 |
Intoxication caused by new psychostimulants: analytical methods to disclose acute and chronic use of benzofurans and ethylphenidate.
Topics: Benzofurans; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Hair; Humans; Immunoassay; Male; Methylphenidate; Psychotropic Drugs; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry; Young Adult | 2017 |
Synthesis and in vitro study of benzofuran hydrazone derivatives as novel alpha-amylase inhibitor.
Topics: alpha-Amylases; Benzofurans; Binding Sites; Catalytic Domain; Enzyme Inhibitors; Hydrazones; Hydrogen Bonding; Inhibitory Concentration 50; Molecular Docking Simulation; Structure-Activity Relationship | 2017 |
Cytotoxic dihydrobenzofuran neolignans from Mappianthus iodoies.
Topics: Benzofurans; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Humans; Lignans; Magnetic Resonance Spectroscopy; Magnoliopsida; Molecular Conformation; Plant Leaves; Plant Stems | 2017 |
Synthesis and 2D-QSAR Study of Active Benzofuran-Based Vasodilators.
Topics: Animals; Aorta; Benzofurans; Chemistry Techniques, Synthetic; Inhibitory Concentration 50; Mice; Molecular Structure; Quantitative Structure-Activity Relationship; Rats; Vasodilator Agents | 2017 |
Benzofuran-dihydropyridine hybrids: A new class of potential bone anabolic agents.
Topics: Administration, Oral; Anabolic Agents; Animals; Benzofurans; Bone Morphogenetic Protein 2; Bone Regeneration; Dihydropyridines; Dose-Response Relationship, Drug; Female; Models, Molecular; Molecular Structure; Osteoblasts; Osteogenesis; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2017 |
Microwave-assisted synthesis of novel 5-substituted benzylidene amino-2-butyl benzofuran-3-yl-4-methoxyphenyl methanones as antileishmanial and antioxidant agents.
Topics: Antioxidants; Antiprotozoal Agents; Benzofurans; Benzylidene Compounds; Biological Availability; Cell Proliferation; Dose-Response Relationship, Drug; Leishmania donovani; Microbial Sensitivity Tests; Microwaves; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2018 |
Discovery of EBI-1051: A novel and orally efficacious MEK inhibitor with benzofuran scaffold.
Topics: Administration, Oral; Animals; Benzofurans; Cell Line, Tumor; Cell Survival; Drug Evaluation, Preclinical; Enzyme Activation; Humans; Mice; Mice, Nude; Mitogen-Activated Protein Kinase Kinases; Neoplasms; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Transplantation, Heterologous | 2018 |
Total Synthesis of the Flavonoid Natural Product Houttuynoid A.
Topics: Aldehydes; Antiviral Agents; Benzofurans; Biological Products; Catalysis; Chalcone; Flavonoids; Ketones | 2018 |
Discovery of novel potent HCV NS5B polymerase non-nucleoside inhibitors bearing a fused benzofuran scaffold.
Topics: Animals; Antiviral Agents; Benzofurans; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; HIV; Humans; Microbial Sensitivity Tests; Molecular Structure; Rats; Structure-Activity Relationship; Viral Nonstructural Proteins | 2018 |
A new benzofuran from Artemisia halodendron Turcz. ex Bess.
Topics: Artemisia; Benzofurans; Ethanol; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; NF-kappa B; Plant Extracts | 2019 |
Synthesis of Benzofuran-2-One Derivatives and Evaluation of Their Antioxidant Capacity by Comparing DPPH Assay and Cyclic Voltammetry.
Topics: Acetonitriles; Alkylation; Antioxidants; Benzofurans; Biphenyl Compounds; Electrochemistry; Kinetics; Methanol; Oxidation-Reduction; Phenols; Picrates; Regression Analysis; Solvents | 2018 |
Development of coumarin-benzofuran hybrids as versatile multitargeted compounds for the treatment of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzofurans; Binding Sites; Cholinesterase Inhibitors; Coumarins; Donepezil; Drug Design; Humans; Molecular Docking Simulation; Peptide Fragments; Structure-Activity Relationship | 2018 |
Benzofuran-pyran hybrids: A new class of potential bone anabolic agents.
Topics: Anabolic Agents; Benzofurans; Bone and Bones; Bone Density; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Humans; Mesenchymal Stem Cells; Molecular Structure; Osteoblasts; Osteogenesis; Pyrans; RNA, Messenger; Structure-Activity Relationship | 2018 |
A short synthesis of Dronedarone.
Topics: Benzofurans; Dronedarone; Ketones; Molecular Structure; Quinones | 2018 |
Chemo-enzymatic synthesis of (E)-2,3-diaryl-5-styryl-trans-2,3-dihydrobenzofuran-based scaffolds and their in vitro and in silico evaluation as a novel sub-family of potential allosteric modulators of the 90 kDa heat shock protein (Hsp90).
Topics: Allosteric Regulation; Benzofurans; Chemistry Techniques, Synthetic; Computer Simulation; Enzymes; HSP90 Heat-Shock Proteins; Molecular Docking Simulation; Protein Conformation; Structure-Activity Relationship | 2018 |
Unraveling the molecular mechanism of benzothiophene and benzofuran scaffold-merged compounds binding to anti-apoptotic Myeloid cell leukemia 1.
Topics: Apoptosis; Benzofurans; Least-Squares Analysis; Molecular Docking Simulation; Molecular Dynamics Simulation; Myeloid Cell Leukemia Sequence 1 Protein; Quantitative Structure-Activity Relationship; Reproducibility of Results; Thiophenes | 2019 |
Design, synthesis and biological evaluation of benzofuran appended benzothiazepine derivatives as inhibitors of butyrylcholinesterase and antimicrobial agents.
Topics: Acetylcholinesterase; Anti-Infective Agents; Benzofurans; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Drug Design; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Inhibitory Concentration 50; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship; Thiazepines | 2018 |
Discovery of dihydrobenzofuran neolignans from Rubus ideaus L. with enantioselective anti-Aβ
Topics: Amyloid beta-Peptides; Benzofurans; Binding Sites; Circular Dichroism; Fruit; Lignans; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Docking Simulation; Peptide Fragments; Plant Extracts; Protein Structure, Tertiary; Rubus; Stereoisomerism | 2018 |
A New Pathway for the Synthesis of a New Class of Blue Fluorescent Benzofuran Derivatives.
Topics: Acetophenones; Benzofurans; Microwaves; Molecular Structure | 2018 |
Design and synthesis of novel 6-hydroxy-4-methoxy-3-methylbenzofuran-7-carboxamide derivatives as potent Mnks inhibitors by fragment-based drug design.
Topics: Amides; Antineoplastic Agents; Benzofurans; Binding Sites; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Drug Design; Humans; Intracellular Signaling Peptides and Proteins; Molecular Dynamics Simulation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Structure-Activity Relationship | 2018 |
Dynamic Kinetic Resolution for Construction of Three Transannular Stereocenters of Dihydrobenzofuranols.
Topics: Benzofurans; Catalysis; Hydrogenation; Kinetics; Models, Molecular; Molecular Conformation; Stereoisomerism | 2018 |
A Concise Synthesis of Potential COX Inhibitor BRL-37959 and Analogs Involving Bismuth(III) Catalyzed Friedel-Crafts Acylation.
Topics: Acylation; Aldehydes; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Bismuth; Catalysis; Cyclooxygenase Inhibitors; Microwaves; Temperature | 2018 |
Synthesis of New 2-Arylbenzo[
Topics: Benzofurans; Carbonates; Catalysis; Ethanol; Molecular Structure; Palladium; Potassium; Water | 2018 |
Evaluating the biological properties of synthetic 4-nitrophenyl functionalized benzofuran derivatives with telomeric DNA binding and antiproliferative activities.
Topics: Antineoplastic Agents; Benzofurans; Cell Proliferation; Cell Survival; DNA; Drug Screening Assays, Antitumor; Humans; Nitrophenols; PC-3 Cells; S Phase Cell Cycle Checkpoints; Structure-Activity Relationship; Telomere | 2019 |
Benzofuran-appended 4-aminoquinazoline hybrids as epidermal growth factor receptor tyrosine kinase inhibitors: synthesis, biological evaluation and molecular docking studies.
Topics: Adenosine Triphosphate; Apoptosis; Benzofurans; Binding Sites; Cell Line, Tumor; Enzyme Inhibitors; ErbB Receptors; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Phosphorylation; Proton Magnetic Resonance Spectroscopy; Quinazolines; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship | 2018 |
Bacterial respiratory tract inflammation in neonatal rat model is attenuated by benzofuran through inhibition of GATA3.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Benzofurans; Bronchoconstrictor Agents; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; GATA3 Transcription Factor; Histocytochemistry; Inflammation; Lung; Methacholine Chloride; Rats; Serum; Treatment Outcome | 2018 |
Synthesis, biological evaluation and molecular dynamic simulations of novel Benzofuran-tetrazole derivatives as potential agents against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzofurans; Caenorhabditis elegans; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Molecular Dynamics Simulation; Molecular Structure; Protein Aggregates; Structure-Activity Relationship; Tetrazoles | 2019 |
Novel Benzo[B]Furans with Anti-Microtubule Activity Upregulate Expression of Apoptotic Genes and Arrest Leukemia Cells in G2/M Phase.
Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Cell Cycle Checkpoints; Cell Division; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; G2 Phase; Humans; Molecular Structure; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Up-Regulation | 2019 |
Synthesis, molecular docking and cholinesterase inhibitory activity of hydroxylated 2-phenylbenzofuran derivatives.
Topics: Acetylcholinesterase; Benzofurans; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Structure-Activity Relationship | 2019 |
Novel benzofuran derivative DK-1014 attenuates lung inflammation via blocking of MAPK/AP-1 and AKT/mTOR signaling in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Benzofurans; Cells, Cultured; Cytokines; Disease Models, Animal; Humans; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide; Pneumonia; Proto-Oncogene Proteins c-akt; Respiratory Mucosa; Signal Transduction; TOR Serine-Threonine Kinases; Transcription Factor AP-1 | 2019 |
Antiproliferative effect of a benzofuran derivate based on the structure of amiodarone on Leishmania donovani affecting mitochondria, acidocalcisomes and intracellular Ca
Topics: Amiodarone; Animals; Benzofurans; Calcium; Cell Line; Cell Survival; Cytoplasm; Drug Discovery; Homeostasis; Inhibitory Concentration 50; Leishmania donovani; Leishmaniasis, Visceral; Macrophages; Metabolic Networks and Pathways; Mice; Mitochondria; Trypanocidal Agents | 2019 |
Isolation, Structure Elucidation, and Total Synthesis of Myrtuspirone A from Myrtus communis.
Topics: Anti-Bacterial Agents; Benzofurans; Cyclohexanes; Gram-Positive Bacteria; Molecular Structure; Myrtus; Phloroglucinol; Plant Leaves; Stereoisomerism | 2019 |
Lithocarols A-F, six tenellone derivatives from the deep-sea derived fungus Phomopsis lithocarpus FS508.
Topics: Antineoplastic Agents; Ascomycota; Benzofurans; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship | 2019 |
Two new compounds from the heartwood of
Topics: Anti-Infective Agents; Benzofurans; Candida albicans; Dalbergia; Escherichia coli; Flavonoids; Microbial Sensitivity Tests; Molecular Structure; Salmonella enterica; Spectrum Analysis; Staphylococcus aureus | 2020 |
Synthesis of New Derivatives of Benzofuran as Potential Anticancer Agents.
Topics: Antineoplastic Agents; Benzofurans; Caspase 3; Caspase 7; Cell Death; Cell Line, Tumor; DNA; Human Umbilical Vein Endothelial Cells; Humans; Inhibitory Concentration 50 | 2019 |
Linderalides A-D, Disesquiterpenoid-Geranylbenzofuranone Conjugates from Lindera aggregata.
Topics: Benzofurans; Lindera; Plant Roots; Sesquiterpenes; Stereoisomerism | 2019 |
Design, synthesis and anticervical cancer activity of new benzofuran-pyrazol-hydrazono- thiazolidin-4-one hybrids as potential EGFR inhibitors and apoptosis inducing agents.
Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Cell Proliferation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; ErbB Receptors; Female; HeLa Cells; Humans; Hydrazones; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Pyrazoles; Structure-Activity Relationship; Thiazolidinediones; Uterine Cervical Neoplasms | 2019 |
A New Meroterpene, A New Benzofuran Derivative and Other Constituents from Cultures of the Marine Sponge-Associated Fungus
Topics: Acremonium; Animals; Benzofurans; Cholinesterase Inhibitors; Circular Dichroism; Ergosterol; Flavins; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Porifera; Terpenes | 2019 |
Sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as potent carbonic anhydrase II/IX/XII inhibitors.
Topics: Benzofurans; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Isoenzymes; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Sulfonic Acids; Thiophenes | 2019 |
Benzo[a]pyrene and 2,3-benzofuran induce divergent temporal patterns of AhR-regulated responses in zebrafish embryos (Danio rerio).
Topics: Animals; Benzo(a)pyrene; Benzofurans; Cytochrome P-450 CYP1A1; Embryo, Nonmammalian; Receptors, Aryl Hydrocarbon; Toxicity Tests; Transcription, Genetic; Water Pollutants, Chemical; Zebrafish; Zebrafish Proteins | 2019 |
Identification of A Novel Class of Benzofuran Oxoacetic Acid-Derived Ligands that Selectively Activate Cellular EPAC1.
Topics: Acetates; Benzofurans; Binding Sites; Cell Line; Cyclic AMP; Guanine Nucleotide Exchange Factors; High-Throughput Screening Assays; Humans; Ligands; Models, Molecular; Molecular Docking Simulation; Molecular Structure | 2019 |
Novel tacrine-benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Benzofurans; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Humans; Models, Molecular; Molecular Structure; Neuroprotective Agents; Structure-Activity Relationship; Tacrine | 2020 |
Antioxidant and anti-browning property of 2-arylbenzofuran derivatives from Morus alba Linn root bark.
Topics: Antioxidants; Benzofurans; Color; Molecular Docking Simulation; Morus; Oxidation-Reduction; Plant Bark; Plant Extracts; Plant Roots | 2020 |
Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and
Topics: Antigens, Neoplasm; Antineoplastic Agents; Benzofurans; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Sulfonamides | 2020 |
Synthesis of Elaborate Benzofuran-2-carboxamide Derivatives through a Combination of 8-Aminoquinoline Directed C-H Arylation and Transamidation Chemistry.
Topics: Amides; Aminoquinolines; Benzene Derivatives; Benzofurans; Catalysis; Molecular Structure | 2020 |
Design, synthesis, and biological evaluation of novel 4H-chromen-4-one derivatives as antituberculosis agents against multidrug-resistant tuberculosis.
Topics: Animals; Antitubercular Agents; Benzofurans; Benzopyrans; Drug Design; Humans; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Microsomes, Liver; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis, Multidrug-Resistant | 2020 |
Exploring resveratrol dimers as virulence blocking agents - Attenuation of type III secretion in Yersinia pseudotuberculosis and Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Benzofurans; Drug Discovery; Flavonoids; Genes, Reporter; Green Fluorescent Proteins; Phenols; Pseudomonas aeruginosa; Resveratrol; Stilbenes; Type III Secretion Systems; Virulence; Yersinia pseudotuberculosis | 2020 |
ZnO-nanorods Promoted Synthesis of α-amino Nitrile Benzofuran Derivatives using One-pot Multicomponent Reaction of Isocyanides.
Topics: Benzofurans; Catalysis; Cyanides; Molecular Structure; Nanotubes; Nitriles; Zinc Oxide | 2020 |
4-Hydroxy-3-methylbenzofuran-2-carbohydrazones as novel LSD1 inhibitors.
Topics: Benzofurans; Binding Sites; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Histone Demethylases; Humans; Hydrazones; Inhibitory Concentration 50; Molecular Docking Simulation; Structure-Activity Relationship | 2020 |
[A new antimicrobial isobenzoisofuran compound from Cassia pumila].
Topics: Anti-Bacterial Agents; Benzofurans; Cassia; Levofloxacin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Phytochemicals; Plants, Medicinal | 2020 |
Synthesis, cytotoxicity, and molecular docking of substituted 3-(2-methylbenzofuran-3-yl)-5-(phenoxymethyl)-1,2,4-oxadiazoles.
Topics: Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Molecular Docking Simulation; Molecular Structure; Oxadiazoles; Structure-Activity Relationship | 2020 |
Design, synthesis, in vitro and in silico studies of 2, 3-diaryl benzofuran derivatives as antitubercular agents.
Topics: Antitubercular Agents; Benzofurans; Cell Line; Dose-Response Relationship, Drug; Drug Design; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship | 2020 |
Total Synthesis of Benzofuran-Based Aspergillusene B via Halogenative Aromatization of Enones.
Topics: Benzofurans; Biological Products; Halogenation; Ketones; Molecular Structure; Stereoisomerism | 2020 |
Benzofuran-selenadiazole hybrids as novel α-glucosidase and cyclooxygenase-2 inhibitors with antioxidant and cytotoxic properties.
Topics: alpha-Glucosidases; Antioxidants; Azoles; Benzofurans; Binding Sites; Catalytic Domain; Cell Line; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Glycoside Hydrolase Inhibitors; Humans; Kinetics; Lipopolysaccharides; MCF-7 Cells; Molecular Conformation; Molecular Docking Simulation; Reactive Oxygen Species; Structure-Activity Relationship | 2020 |
Substituted benzothiophene and benzofuran derivatives as a novel class of bone morphogenetic Protein-2 upregulators: Synthesis, anti-osteoporosis efficacies in ovariectomized rats and a zebrafish model, and ADME properties.
Topics: Animals; Benzofurans; Bone Morphogenetic Protein 2; Caco-2 Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mice; Mice, Inbred BALB C; Molecular Structure; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiophenes; Zebrafish | 2020 |
Seven new chemical constituents from the underground parts of Eupatorium chinense.
Topics: Antineoplastic Agents, Phytogenic; Benzofurans; China; Eupatorium; Hep G2 Cells; Humans; Molecular Structure; Phytochemicals; Plant Roots; Sesquiterpenes | 2020 |
Synthesis, in vitro urease inhibitory potential and molecular docking study of benzofuran-based-thiazoldinone analogues.
Topics: Benzofurans; Dose-Response Relationship, Drug; Enzyme Inhibitors; Molecular Docking Simulation; Structure-Activity Relationship; Urease | 2020 |
Novel bis(pyrazole-benzofuran) hybrids possessing piperazine linker: Synthesis of potent bacterial biofilm and MurB inhibitors.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Benzofurans; Biofilms; Carbohydrate Dehydrogenases; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Drug Screening Assays, Antitumor; Enterococcus faecalis; Escherichia coli; Humans; Microbial Sensitivity Tests; Molecular Structure; Piperazine; Pyrazoles; Staphylococcus aureus; Structure-Activity Relationship | 2020 |
Structural revision of sesbagrandiflorains A and B, and synthesis and biological evaluation of 6-methoxy-2-arylbenzofuran derivatives.
Topics: Benzofurans; Humans; Molecular Structure | 2021 |
Modulation of benzofuran structure as a fluorescent probe to optimize linear and nonlinear optical properties and biological activities.
Topics: Algorithms; Benzofurans; Chemical Phenomena; Fluorescent Dyes; Models, Molecular; Molecular Conformation; Molecular Structure; Spectrum Analysis; Structure-Activity Relationship | 2020 |
Evaluation of sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as inhibitors of nucleotide pyrophosphatases/phosphodiesterases and anticancer agents.
Topics: Antineoplastic Agents; Benzofurans; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Molecular Docking Simulation; Molecular Structure; Phosphoric Diester Hydrolases; Pyrophosphatases; Structure-Activity Relationship; Sulfonic Acids; Thiophenes; Tumor Cells, Cultured | 2020 |
Identification of novel STAT3 inhibitors bearing 2-acetyl-7-phenylamino benzofuran scaffold for antitumour study.
Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Binding Sites; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Design; G2 Phase Cell Cycle Checkpoints; Humans; Molecular Docking Simulation; Phosphorylation; src Homology Domains; STAT3 Transcription Factor; Structure-Activity Relationship | 2020 |
Therapeutic Path to Double Knockout: Investigating the Selective Dual-Inhibitory Mechanisms of Adenosine Receptors A1 and A2 by a Novel Methoxy-Substituted Benzofuran Derivative in the Treatment of Parkinson's Disease.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Antiparkinson Agents; Benzofurans; Catalytic Domain; Computer Simulation; Drug Design; Humans; Ligands; Molecular Conformation; Parkinson Disease; Principal Component Analysis; Protein Binding; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Purinergic P1; Structure-Activity Relationship; Thermodynamics | 2021 |
Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Benzofurans; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Quorum Sensing; Structure-Activity Relationship; Tumor Cells, Cultured | 2021 |
Synthesis and in vitro study of nitro- and methoxy-2-phenylbenzofurans as human monoamine oxidase inhibitors.
Topics: Benzofurans; Binding Sites; Blood-Retinal Barrier; Cell Line, Tumor; Cell Survival; Humans; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Structure, Tertiary; Structure-Activity Relationship | 2021 |
A Solvent-free, Catalyst-free Formal [3+3] Cycloaddition Dearomatization Strategy: Towards New Fluorophores for Biomolecules Labelling.
Topics: Anisoles; Benzofurans; Catalysis; Cycloaddition Reaction; Fluorescent Dyes; Heterocyclic Compounds; Hydrocarbons, Aromatic; Immunoglobulin G; Indoles; Molecular Structure; Optical Imaging; Pyrones; Pyrroles; Serum Albumin, Bovine; Solvents | 2021 |
Synthesis of Moracin C and Its Derivatives with a 2-arylbenzofuran Motif and Evaluation of Their PCSK9 Inhibitory Effects in HepG2 Cells.
Topics: Benzofurans; Cell Proliferation; Enzyme Inhibitors; Hep G2 Cells; Humans; PCSK9 Inhibitors; Stilbenes | 2021 |
Exploration of benzofuran-based compounds as potent and selective Plasmodium falciparum glycogen synthase kinase-3 (PfGSK-3) inhibitors.
Topics: Benzofurans; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3; Humans; Molecular Structure; Plasmodium falciparum; Protein Kinases; Structure-Activity Relationship | 2021 |
Investigation of the arcane inhibition of human organic anion transporter 3 by benzofuran antiarrhythmic agents.
Topics: Amiodarone; Anti-Arrhythmia Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Atrial Fibrillation; Benzofurans; Cell Line; Dronedarone; Drug Interactions; HEK293 Cells; Humans; Organic Anion Transporters, Sodium-Independent; Rivaroxaban | 2021 |
Design, synthesis and biological evaluation of novel benzofuran derivatives as potent LSD1 inhibitors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzofurans; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Histone Demethylases; Humans; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship | 2021 |
Development of 3-methyl/3-(morpholinomethyl)benzofuran derivatives as novel antitumor agents towards non-small cell lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Development; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Molecular Structure; Structure-Activity Relationship | 2021 |
Synthesis, biological evaluation and molecular modeling of benzofuran piperidine derivatives as Aβ antiaggregant.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Benzofurans; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Neuroprotective Agents; Piperidines; Protein Aggregates; Protein Aggregation, Pathological; Structure-Activity Relationship | 2021 |
Development of novel benzofuran-isatin conjugates as potential antiproliferative agents with apoptosis inducing mechanism in Colon cancer.
Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Development; Drug Screening Assays, Antitumor; Humans; Isatin; Molecular Structure; Proto-Oncogene Proteins c-bcl-2 | 2021 |
P2Y14R for inflammation therapy: is it a promising target?
Topics: Anti-Inflammatory Agents; Benzofurans; Benzoic Acid; Biomarkers; Drug Evaluation, Preclinical; Humans; Inflammation; Naphthalenes; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Structure-Activity Relationship; Triazoles | 2021 |
Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds.
Topics: Benzofurans; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Escherichia coli Proteins; Models, Molecular; Molecular Structure; Protein Disulfide-Isomerases; Structure-Activity Relationship | 2021 |
Analysis of Hsp90 allosteric modulators interactome reveals a potential dual action mode involving mitochondrial MDH2.
Topics: Allosteric Regulation; Antineoplastic Agents; Benzofurans; Dose-Response Relationship, Drug; HSP90 Heat-Shock Proteins; Humans; Malate Dehydrogenase; Models, Molecular; Molecular Structure; Structure-Activity Relationship | 2021 |
Single-cell analysis of regions of interest (SCARI) using a photosensitive tag.
Topics: Benzofurans; CD8-Positive T-Lymphocytes; Humans; Nitrophenols; Single-Cell Analysis | 2021 |
Anti-Inflammatory Properties of Longifuran A, a New Benzofuran from the Stems of Amomum longiligulare.
Topics: Amomum; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Dose-Response Relationship, Drug; Lipopolysaccharides; Mice; Molecular Structure; Nitric Oxide; Plant Stems; RAW 264.7 Cells | 2021 |
Discovery of Sortase A covalent inhibitors with benzofuranene cyanide structures as potential antibacterial agents against Staphylococcus aureus.
Topics: Aminoacyltransferases; Anti-Bacterial Agents; Bacterial Proteins; Benzofurans; Binding Sites; Biofilms; Cyanides; Cysteine Endopeptidases; Drug Design; Enzyme Inhibitors; HEK293 Cells; Humans; Molecular Docking Simulation; Staphylococcus aureus; Structure-Activity Relationship | 2022 |
Total Synthesis of the Natural Chalcone Lophirone E, Synthetic Studies toward Benzofuran and Indole-Based Analogues, and Investigation of Anti-Leishmanial Activity.
Topics: Antiparasitic Agents; Benzofurans; Biflavonoids; Chalcones; Chemical Phenomena; Chemistry Techniques, Synthetic; Humans; Indoles; Leishmania infantum; Molecular Structure; Structure-Activity Relationship | 2022 |
Protein Binding of Benzofuran Derivatives: A CD Spectroscopic and In Silico Comparative Study of the Effects of 4-Nitrophenyl Functionalized Benzofurans and Benzodifurans on BSA Protein Structure.
Topics: Benzofurans; Binding Sites; Circular Dichroism; Molecular Docking Simulation; Nitrophenols; Protein Binding; Serum Albumin, Bovine; Spectrometry, Fluorescence; Thermodynamics | 2022 |
Synthesis of the New 1-(7-Methoxy-1-benzofuran-2-yl)-3-(4-methylphenyl)prop-2-en-1-one and Controlling of Spectroscopic, Optical and Conductivity Properties by Concentration.
Topics: Benzofurans; Carbon-13 Magnetic Resonance Spectroscopy; Chalcone; Proton Magnetic Resonance Spectroscopy; Spectroscopy, Fourier Transform Infrared | 2022 |
Identification of 3-(piperazinylmethyl)benzofuran derivatives as novel type II CDK2 inhibitors: design, synthesis, biological evaluation, and
Topics: Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Structure-Activity Relationship | 2022 |
Green synthesis of 2-benzylidene-1-benzofuran-3-ones and in vitro neuraminidase study using molecular docking.
Topics: Antiviral Agents; Benzofurans; Binding Sites; Enzyme Inhibitors; Molecular Docking Simulation; Neuraminidase; Quantitative Structure-Activity Relationship | 2022 |