benzocaine and lidocaine

benzocaine has been researched along with lidocaine in 170 studies

Research

Studies (170)

Timeframe	Studies, this research(%)	All Research%
pre-1990	60 (35.29)	18.7374
1990's	25 (14.71)	18.2507
2000's	43 (25.29)	29.6817
2010's	34 (20.00)	24.3611
2020's	8 (4.71)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Duffy, EM; Jorgensen, WL	1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M	1
Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM	1
Ahman, M; Holmén, AG; Wan, H	1
Batts, TW; Brown, ML; Jones, PJ; Landry, V; Patel, MK; Wang, Y	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Brouillette, WJ; Brown, GB; Zha, C	1
Chłoń-Rzepa, G; Dąbrowska, M; Jankowska, A; Komsta, Ł; Pawłowski, M; Ślusarczyk, M; Starek, M; Zagórska, A	1
Hille, B	1
Hille, B; Palade, PT; Schwarz, W	1
Bisby, MA	1
Jeppsson, R	1
Ritchie, JM	2
Gill, CJ; Orr, DL	1
Koblin, DD; Lester, HA	1
Mrose, HE; Ritchie, JM	1
DeStefano, MJ; Rabinovitch, M	1
Cohen, EN; Kendig, JJ	1
Bassett, LW; Canalis, RF; Hanafee, WN	1
Coate, RA; Kralemann, H	1
Johnson, HL; Maibach, HI	1
Takman, BH	1
Punnia-Moorthy, A; Vickers, ER	1
Ikemoto, Y; Oda, M; Yoshida, A	1
Guertler, AT; Lagutchik, MS; Martin, DG	1
Williams, AR	1
Abuzeid, M; Aksel, S; Alexander, SE; Lorino, CO; Prough, SG; Wiebe, RH	1
Ohishi, K; Suzuki, T; Uchida, MK	1
Chapula, JS	1
Keynes, RD	1
Charbonneau, M	1
Oehring, H; Walther, D; Welker, D; Wolf, D	1
Enyeart, JJ; Hinkle, PM; Phillips, WJ	1
Casey, MP; Hansen-Flaschen, J; Kotler, RL	1
Carr, HS; Czinn, SJ; Speck, WT	1
Abe, K; Mashimo, T; Yoshiya, I	1
Applebee, K; Cooper, JE; Mahaffey, P	1
Danilo, P; Rosen, MR; Spinelli, W	1
Foxworth, JW; Mahmoud, SF; Roberts, JA	1
Gallová, J; Ondrias, K; Stolc, S; Szöcsová, H	1
Nae, C; Sahini, VE; Tripşa, M; Vasilescu, V	1
Graham, DY; Opekun, A; Smith, JL	1
Hoffman, BF	1
Adriani, J; Beuttler, WA; Brihmadesam, L; Naraghi, M	1
Bohn, E; Kunze, H; Vogt, W	1
Campbell, AH; Lord, GH; Suskevich, J	1
Büchi, J; Koller, RJ; Perlia, X	1
Demetrescu, M; Julien, RM	2
Arhem, P; Frankenhaeuser, B	1
Furkert, K	1
Baron, JH; Thambugala, RL	1
Ritchie, BR; Ritchie, JM	1
Campbell, AH; Lord, GH; Stasse, JA; Willson, JE	1
Büchi, J; Doulakas, J; Perlia, X	1
Bekkers, JM; Greeff, NG; Keynes, RD; Neumcke, B	1
Schmidtmayer, J; Ulbricht, W	1
Ehrenstein, G; Huang, LM	1
Josephson, IR; Sanchez-Chapula, J; Tsuda, Y	1
Gintant, GA; Hoffman, BF; Naylor, RE	1
Hiramatsu, M; Ichikawa, M; Kashimata, M; Maruyama, S; Minami, N; O, K; Sato, N; Shimada, M; Tajima, M; Ueta, Y	1
Gardner, AF	1
Akutagawa, T; Collins, JG; Katz, JD; Kitahata, LM; Saito, H	1
West, HH	1
Anderson, ER; Foulks, JG; Godin, DV	1
Bell, FP	1
Frömming, KH; Ghaly, GM	1
Fisher, AA	1
Angelillo, VA; Moss, LM; O'Donohue, WJ	1
Andresen, MC; Brodwick, M; Yang, M	1
Dinneen, SF; Fairbanks, VF; Mohr, DN	1
Hanck, DA; Makielski, JC; Sheets, MF	1
Chebabo, SR; do Carmo, RJ; Martins-Ferreira, H	1
Langton, JA; Raphael, JH; Stanley, GD	1
Bircher, AJ; Messmer, SL; Rufli, T; Surber, C	1
Ackerman, EW; Breimer, DD; Grouls, RJ; Hellebrekers, LJ; Korsten, HH; Machielsen, E	1
Colella, G; Grimaldi, PL; Tartaro, GP	1
Amano, K	1
Quan, C; Wang, GK; Wang, S	1
Quan, C; Wang, GK; Wang, SY	1
Backx, PH; Sah, RL; Tsushima, RG	1
Lilley, SJ; Robbins, J	1
Arledge, JA; Durieux, ME; Hönemann, CW; Sullivan, LM	1
Backx, PH; Dime, DS; Himmeldirk, K; Li, RA; Tsushima, RG	1
Armbruster, SC; Tongier, WK; White, PF; Wong, JK	1
Gimbel, HV; Hamilton, RC; Sun, R	1
Mutlu, Z; Tulga, F	1
Helfman, M	1
Baker, MD	1
Dunn, BM; Kern, K; Langevin, PB	1
Byford, AM; Durieux, ME; Fischer, LG; Hollmann, MW	1
Ackerman, E; Breimer, D; Grouls, R; Hellebrekers, L; Korsten, E; van Zundert, A	1
Atlas, G; Mort, T	1
Lewis, JW; Lorelli, DR; Morris, DE	1
de Klaver, M; Durieux, ME; Henle, P; Hollmann, MW; Kamatchi, GL; Ritter, CH	1
Carr, MP; Horton, JE	1
Lavrador, MA; Rosa, AL; Sverzut, CE; Xavier, SP	1
Brown, L; Hinson, RM; Voelker, CA	1
Fukayama, H; Suzuki, N; Umino, M	1
Meechan, JG	1
Picton, P; Wilkins, AN	1
Erickson, PR; Hodges, JS; Stecker, SS; Swift, JQ	1
Johnson, J; Primosch, RE	1
ADRIANI, J; ZEPERNICK, R	1
MAGGIORELLI, E	1
Cristea, M; Kolesnikov, YA; Pasternak, GW	1
Amin, AS; el-Didamony, AM	1
Chan, TC; Davis, DP; Jin, A; Vilke, GM	1
de Nucci, G; de Paula, E; Donato, JL; Pereira, R; Pinto, LM; Santana, MH	1
Mitchell, J; Moczydlowski, E; Wang, GK; Wang, SY	1
Günay, I; Güven, M; Mert, T	1
Abu Al-Melh, M; Andersson, L; Behbehani, E	1
Paparella, S	1
Benz, C; Hickel, R; Huth, KC; Paschos, E; Reeka-Bardschmidt, A	1
Weiser, T	1
Brkić, S; Jovanović, M; Karadaglić, D	1
Glick, N; Jacka, MJ; Kruger, M	1
de Paula, E; Fraceto, LF; Nakaie, CR; Oyama, S; Pertinhez, TA; Spisni, A	1
Bruhova, I; Tikhonov, DB; Zhorov, BS	1
Al-Melh, MA; Andersson, L	1
Keceli, MB; Purali, N	1
Darczuk, D; Gończowski, K; Kesek, B; Zapała, J; Zarzecka, J	1
Carlson, JF; Hodges, JS; Michalowicz, BS; Osborn, JB; Stoltenberg, JL	1
Ahern, CA; Dougherty, DA; Eastwood, AL; Horn, R	1
Konrádsdóttir, F; Loftsson, T; Sigfússon, SD	1
Guay, J	1
Damiano, DB; Fenton, OS; Frederick, KA; Noonan, KY; Tonge, LA	1
Fozzard, HA; Hanck, DA; Lipkind, GM; McNulty, MM; Nikitina, E; Sheets, MF	1
Chen, JW; English, J; Jeske, AH; Reznik, DS	1
Ganzberg, S; Kramer, KJ	1
Trapp, L; Will, J	1
Engkilde, K; Johansen, JD; Menné, T; Thyssen, JP	1
Bonina, F; Castelli, F; Chiechio, S; Puglia, C; Sarpietro, MG; Zammataro, M	1
Beck, M; Drum, M; Reader, A	1
Baird, JA; Rinaldi, C; Santiago-Quinonez, D; Taylor, LS	1
Paphangkorakit, J; Priprem, A; Sangsirinakagul, C	1
Ahern, CA; Goodchild, SJ; Lee, S	1
Ahern, CA; Pless, SA; Rivera-Acevedo, RE; Schwarz, SK	1
Deepika, A; Rao, CR; Rao, VV; Uloopi, KS; Vinay, C	1
Beavers, N; Brackett, R; Guelmann, M; Primosch, RE	1
Kenkel, J; Oni, G; Rasko, Y	1
Ichinohe, T; Matsuura, N; Nakamura, S	1
Arnabat-Domínguez, J; Berini-Aytés, L; Gay-Escoda, C; Mayor-Subirana, G; Valmaseda-Castellón, E; Yagüe-García, J	1
Beck, M; Drum, M; Fullmer, S; Nusstein, J; Reader, A	1
Gangnes, RA; Garg, R; Liaw, LH; Sanderson, AR; Wu, EC	1
Hersh, EV; Saraghi, M	1
Boyne, MT; Colatsky, T; Hartman, NR; Mao, JJ; Patel, V; Racoosin, JA; Taylor, K; Wasserman, AM; Zhou, H	1
Casavant, MJ; Gerona, RR; Ho, RY; Russell, JL; Spiller, HA	1
de Gannes, G; Kossintseva, I; To, D	1
Doyle, DJ	1
Blaya, DS; de Freiras, GC; Moreira, CH; Pozzobon, RT	1
Duggi, V; Jyostna, P; Kumar, M; Sandeep, V	1
Augusti, R; De Carvalho, TC; Filgueiras, PR; França, HS; Merlo, BB; Ortiz, RS; Rodrigues, RR; Romão, W; Santos, H; Souza, LM; Tosato, F; Vaz, BG	1
DiMarco, AC; Wetmore, AO	1
Boyne, M; Colatsky, T; Hartman, N; Mans, D; Mao, J; Patel, V; Zhou, H	1
Cheng, C; Gaydarova, R; Ivanoff, CS; Kevorkyan, S; Mirzajani, H; Tomlekova, D; Wu, JJ; Yuan, Q	1
Abdollahi, AA; Froughreyhani, M; Jafarabadi, MA; Milani, AS; Zakeri-Milani, P; Zand, V	1
Misell, LM; Palm, MD	1
Qazi, SR; Rehman, N	1
Di Martino, A; Drannikov, A; Marina, TE; Ozaltin, K; Postnikov, PS; Sedlarik, V; Surgutskaia, NS	1
Dubenska, L; Plotycya, S; Pysarevska, S	1
Bui, N; Park, L; Tanbonliong, T; Tom, J; Wilson, M	1
Brignardello-Petersen, R	1
Amini, S; Biria, M; Chiniforush, N; Haeri Boroojeni, HS; Mohaghegh, S; Nokhbatolfoghahaei, H; Shekarchi, F	1
Dick, JE; Kong, EF; Krushinski, LE; Vannoy, KJ	1
Azab, M; Brignardello-Petersen, R; Carrasco-Labra, A; Diaz Martinez, JP; He, L; Hersh, EV; Ibrahim, S; Miroshnychenko, A; Moore, PA; Polk, DE; Roldan, Y; Tamilselvan, D; Tampi, M; Urquhart, O	1
Daftari, G; Jelodar, MR; Khajavirad, N	1

Reviews

12 review(s) available for benzocaine and lidocaine

Article	Year
A pharmacological approach to the structure of sodium channels in myelinated axons. Annual review of neuroscience, 1979, Volume: 2 Topics: Aconitine; Action Potentials; Anesthetics, Local; Animals; Anura; Batrachotoxins; Benzocaine; Binding Sites; Chemical Phenomena; Chemistry; Decapodiformes; Ion Channels; Lidocaine; Molecular Conformation; Nerve Fibers, Myelinated; Ranvier's Nodes; Saxitoxin; Tetrodotoxin; Veratridine	1979
Modification of the electrophysiologic matrix by antiarrhythmic drugs. Journal of the American College of Cardiology, 1985, Volume: 5, Issue:6 Suppl Topics: Action Potentials; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzocaine; Electrophysiology; Heart Conduction System; Heart Rate; Humans; Lidocaine; Time Factors; Tocainide; Ventricular Fibrillation	1985
[Otologic agents. 13]. Pharmazeutische Praxis, 1967, Volume: 9 Topics: Adrenal Cortex Hormones; Aminopyrine; Anesthetics, Local; Anti-Bacterial Agents; Anti-Infective Agents, Local; Anti-Inflammatory Agents; Antipyrine; Benzocaine; Chloramphenicol; Disinfectants; Ear Diseases; Formaldehyde; Humans; Hydrocortisone; Lidocaine; Neomycin; Nitrofurazone; Prednisolone; Procaine; Tetracaine; Toluene	1967
[Aphthosis of the oral cavity: therapeutic prospectives]. Minerva stomatologica, 1996, Volume: 45, Issue:6 Topics: Adrenal Cortex Hormones; Anesthetics, Local; Anti-Bacterial Agents; Benzocaine; Humans; Lidocaine; Plants, Toxic; Stomatitis, Aphthous; Tobacco, Smokeless	1996
Effective topical anesthetic agents and techniques. Dental clinics of North America, 2002, Volume: 46, Issue:4 Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Benzocaine; Humans; Injections; Lidocaine; Mouth Mucosa; Needles; Nerve Block; Placebos; Prilocaine; Tetracaine	2002
Topical anesthetic sprays directly associated with a serious, sometimes fatal adverse drug reaction: methemoglobinemia. Journal of emergency nursing, 2005, Volume: 31, Issue:5 Topics: Administration, Topical; Aerosols; Anesthetics, Local; Benzocaine; Dose-Response Relationship, Drug; Emergency Nursing; Humans; Lidocaine; Methemoglobinemia; Tetracaine	2005
Methemoglobinemia related to local anesthetics: a summary of 242 episodes. Anesthesia and analgesia, 2009, Volume: 108, Issue:3 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anemia; Anesthetics, Local; Benzocaine; Child; Child, Preschool; Cocaine; Female; Hemoglobins; Humans; Infant; Lidocaine; Male; Methemoglobinemia; Middle Aged; Pregnancy; Prilocaine; Tetracaine; Young Adult	2009
The use of local anesthetic agents in medicine. Dental clinics of North America, 2010, Volume: 54, Issue:4 Topics: Administration, Topical; Amides; Anesthesia; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Benzocaine; Bupivacaine; Esters; Humans; Lidocaine; Mepivacaine; Nerve Block; Pain, Postoperative; Surgical Procedures, Operative	2010
Acquired methemoglobinemia revisited. Dental clinics of North America, 2010, Volume: 54, Issue:4 Topics: Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Local; Benzocaine; Enzyme Inhibitors; Hemoglobins; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Methemoglobin; Methemoglobinemia; Methylene Blue; Nitrous Oxide; Oxidation-Reduction; Oximetry; Prilocaine	2010
Airway anesthesia: theory and practice. Anesthesiology clinics, 2015, Volume: 33, Issue:2 Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Local; Benzocaine; Fiber Optic Technology; Humans; Intubation, Intratracheal; Laryngeal Nerves; Lidocaine; Nerve Block	2015
Voltammetry of local anesthetics: theoretical and practical aspects. Critical reviews in analytical chemistry, 2021, Volume: 51, Issue:4 Topics: Anesthetics, Local; Benzocaine; Drug Compounding; Electrochemical Techniques; Electrodes; Fluorocarbon Polymers; Hemoglobins; Humans; Lidocaine; Limit of Detection; Metal Nanoparticles; Molecularly Imprinted Polymers; Nanotubes, Carbon; Oxidation-Reduction; Procaine; Reproducibility of Results; Sensitivity and Specificity; Surface Properties	2021
Injectable and topical local anesthetics for acute dental pain: 2 systematic reviews. Journal of the American Dental Association (1939), 2023, Volume: 154, Issue:1 Topics: Acute Pain; Anesthesia, Local; Anesthetics, Local; Benzocaine; Bupivacaine; Epinephrine; Humans; Lidocaine; Mepivacaine; Pulpitis	2023

Trials

31 trial(s) available for benzocaine and lidocaine

Article	Year
A double-blind crossover comparison of topical anesthetics. Journal of the American Dental Association (1939), 1979, Volume: 98, Issue:2 Topics: Administration, Topical; Adult; Anesthetics, Local; Benzocaine; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Lidocaine; Male; Pain; Placebos; Tetracaine	1979
A clinical evaluation of three topical anaesthetic agents. Australian dental journal, 1992, Volume: 37, Issue:4 Topics: Adult; Anesthetics, Local; Benzocaine; Double-Blind Method; Drug Combinations; Female; Humans; Injections; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Mouth Mucosa; Needles; Pain; Placebos; Prilocaine; Tetracaine	1992
Controlled comparison of topical anesthetic agents in flexible upper gastrointestinal endoscopy. Gastrointestinal endoscopy, 1985, Volume: 31, Issue:4 Topics: Adult; Aerosols; Anesthetics, Local; Benzalkonium Compounds; Benzocaine; Cetrimonium Compounds; Drug Combinations; Fiber Optic Technology; Gastroscopes; Gastroscopy; Humans; Lidocaine; Male; Mouthwashes; para-Aminobenzoates; Premedication; Random Allocation; Solutions; Taste; Tetracaine	1985
Effects of topical benzocaine and lignocaine on upper airway reflex sensitivity. Anaesthesia, 1996, Volume: 51, Issue:2 Topics: Administration, Oral; Adult; Ammonia; Anesthetics, Local; Benzocaine; Humans; Larynx; Lidocaine; Male; Nebulizers and Vaporizers; Reflex; Tablets	1996
Clinical evaluation and comparison of 2 topical anesthetics for pain caused by needle sticks and scaling and root planing. Journal of periodontology, 2001, Volume: 72, Issue:4 Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Benzocaine; Bicuspid; Dental Arch; Dental Scaling; Double-Blind Method; Drug Carriers; Female; Gels; Humans; Injections; Lidocaine; Male; Mandible; Maxilla; Middle Aged; Molar; Needles; Pain; Pain Measurement; Placebos; Root Planing; Statistics, Nonparametric	2001
Clinical effectiveness of lidocaine and benzocaine for topical anesthesia. Anesthesia progress, 1999,Summer, Volume: 46, Issue:3 Topics: Adolescent; Adult; Analysis of Variance; Anesthesia, Local; Anesthetics, Local; Benzocaine; Double-Blind Method; Female; Humans; Injections; Lidocaine; Male; Needles; Pain; Pain Measurement; Palate; Placebos; Sex Factors; Treatment Outcome	1999
Comparison of topical anesthesia of 20% benzocaine and 60% lidocaine gel. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2002, Volume: 94, Issue:2 Topics: Adult; Alveolar Process; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Benzocaine; Gels; Humans; Incisor; Lidocaine; Male; Mouth Mucosa; Occlusive Dressings; Pain Measurement; Pain Threshold; Pharmaceutical Vehicles; Placebos; Statistics, Nonparametric	2002
Should a mucoadhesive patch (DentiPatch) be used for gingival anesthesia in children? Anesthesia progress, 2002,Winter, Volume: 49, Issue:1 Topics: Adhesiveness; Adolescent; Age Factors; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Benzocaine; Child; Child, Preschool; Cooperative Behavior; Female; Gingiva; Humans; Lidocaine; Linear Models; Male; Pain Measurement; Pit and Fissure Sealants; Rubber Dams; Sex Factors; Time Factors	2002
Influence of site preparation methods on the pain reported during palatal infiltration using the Wand Local Anesthetic System. American journal of dentistry, 2003, Volume: 16, Issue:3 Topics: Administration, Topical; Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Benzocaine; Female; Humans; Injections; Lidocaine; Male; Needles; Pain; Pain Measurement; Palate; Time Factors	2003
Prospective randomized study of viscous lidocaine versus benzocaine in a GI cocktail for dyspepsia. The Journal of emergency medicine, 2004, Volume: 27, Issue:1 Topics: Adult; Aluminum Hydroxide; Anesthetics, Local; Antacids; Atropine; Benzocaine; Drug Combinations; Drug Therapy, Combination; Dyspepsia; Female; Humans; Lidocaine; Magnesium Hydroxide; Male; Phenobarbital; Prospective Studies; Scopolamine; Simethicone; Single-Blind Method; Treatment Outcome	2004
Reduction of pain from needle stick in the oral mucosa by topical anesthetics: a comparative study between lidocaine/prilocaine and benzocaine. The Journal of clinical dentistry, 2005, Volume: 16, Issue:2 Topics: Adult; Anesthetics, Combined; Anesthetics, Local; Benzocaine; Cuspid; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Mouth Mucosa; Needles; Pain; Pain Measurement; Patient Satisfaction; Prilocaine; Time Factors	2005
Efficacy of intraoral topical anesthetics in children. Journal of dentistry, 2006, Volume: 34, Issue:6 Topics: Administration, Topical; Aerosols; Anesthetics, Combined; Anesthetics, Local; Benzocaine; Child; Child, Preschool; Dental Caries; Dimethyl Sulfoxide; Double-Blind Method; Female; Gels; Heart Rate; Humans; Injections; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Molar; Ointments; Pain Measurement; Pharmaceutic Aids; Placebos; Prilocaine; Tetracaine; Tooth, Deciduous	2006
Comparison of topical anesthetics (EMLA/Oraqix vs. benzocaine) on pain experienced during palatal needle injection. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2007, Volume: 103, Issue:5 Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Benzocaine; Gels; Humans; Injections; Lidocaine; Lidocaine, Prilocaine Drug Combination; Mouth Mucosa; Needles; Ointments; Pain; Pain Measurement; Palate, Hard; Prilocaine; Single-Blind Method	2007
[Comparison of the systems used for providing local anesthesia in dentistry--the Wand (Milestone Scientific) and Injex (Rosch)]. Przeglad lekarski, 2006, Volume: 63, Issue:12 Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Benzocaine; Dental Anxiety; Equipment Design; Facial Pain; Female; Humans; Injections, Intradermal; Injections, Jet; Lidocaine; Male; Needles; Pain Measurement; Patient Satisfaction	2006
A preliminary study of intra-pocket topical versus injected anaesthetic for scaling and root planing. Journal of clinical periodontology, 2007, Volume: 34, Issue:10 Topics: Adult; Aged; Anesthetics, Local; Benzocaine; Dental Scaling; Epidemiologic Methods; Female; Gels; Humans; Injections; Lidocaine; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Periodontal Pocket; Root Planing; Toothache	2007
Comparative efficacy of 2 topical anesthetics for the placement of orthodontic temporary anchorage devices. Anesthesia progress, 2009,Autumn, Volume: 56, Issue:3 Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Local; Benzocaine; Child; Cross-Over Studies; Double-Blind Method; Female; Heart Rate; Humans; Lidocaine; Male; Middle Aged; Orthodontic Anchorage Procedures; Orthodontic Appliances; Oximetry; Pain; Pain Measurement; Phenylephrine; Tetracaine; Time Factors; Vasoconstrictor Agents; Young Adult	2009
Effectiveness of two flavored topical anesthetic agents in reducing injection pain in children: a comparative study. The Journal of clinical pediatric dentistry, 2012,Fall, Volume: 37, Issue:1 Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Benzocaine; Child; Dibucaine; Female; Flavoring Agents; Humans; Injections; Lidocaine; Male; Mandibular Nerve; Needles; Nerve Block; Pain; Pain Measurement; Palate; Tooth Extraction; Tooth Mobility; Tooth, Deciduous; Treatment Outcome	2012
Effect of continuous versus interrupted administration of nitrous oxide-oxygen inhalation on behavior of anxious pediatric dental patients: a pilot study. The Journal of clinical pediatric dentistry, 2012,Fall, Volume: 37, Issue:1 Topics: Anesthesia, Dental; Anesthetics, Inhalation; Anesthetics, Local; Benzocaine; Child; Child Behavior; Child, Preschool; Conscious Sedation; Cooperative Behavior; Crying; Dental Anxiety; Dental Restoration, Permanent; Hemoglobins; Humans; Lidocaine; Movement; Nerve Block; Nitrous Oxide; Oximetry; Oxygen; Pilot Projects; Single-Blind Method; Time Factors	2012
Topical lidocaine enhanced by laser pretreatment: a safe and effective method of analgesia for facial rejuvenation. Aesthetic surgery journal, 2013, Aug-01, Volume: 33, Issue:6 Topics: Administration, Cutaneous; Analgesia; Analysis of Variance; Anesthetics, Combined; Anesthetics, Local; Benzocaine; Biotransformation; Cosmetic Techniques; Equipment Design; Facial Pain; Humans; Laser Therapy; Lasers, Gas; Lasers, Solid-State; Lidocaine; Ointments; Pain Measurement; Rejuvenation; Skin Absorption; Skin Aging; Surveys and Questionnaires; Tetracaine; Texas; Treatment Outcome	2013
A new method of topical anesthesia by using anesthetic solution in a patch. Journal of endodontics, 2013, Volume: 39, Issue:11 Topics: Administration, Mucosal; Adult; Analgesia; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Benzocaine; Cross-Over Studies; Cuspid; Double-Blind Method; Epinephrine; Female; Gingiva; Humans; Lidocaine; Male; Mouth Mucosa; Needles; Pain Measurement; Vasoconstrictor Agents	2013
Anesthetic efficacy of Oraqix® versus Hurricaine® and placebo for pain control during non-surgical periodontal treatment. Medicina oral, patologia oral y cirugia bucal, 2014, Mar-01, Volume: 19, Issue:2 Topics: Adult; Aged; Anesthesia; Anesthetics, Local; Benzocaine; Dental Scaling; Double-Blind Method; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Middle Aged; Pain Management; Prilocaine; Root Planing; Treatment Outcome	2014
Effect of preoperative acetaminophen/hydrocodone on the efficacy of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, randomized, double-blind, placebo-controlled study. Journal of endodontics, 2014, Volume: 40, Issue:1 Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Opioid; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Benzocaine; Double-Blind Method; Drug Combinations; Female; Humans; Hydrocodone; Lidocaine; Lip; Male; Mandibular Nerve; Middle Aged; Nerve Block; Pain Measurement; Patient Satisfaction; Placebos; Premedication; Prospective Studies; Pulpitis; Root Canal Preparation; Treatment Outcome; Young Adult	2014
The effect of topical anesthetic hydration on the depth of thermal injury from the plasma skin regeneration device. Lasers in surgery and medicine, 2014, Volume: 46, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Benzocaine; Burns; Drug Combinations; Female; Hot Temperature; Humans; Lidocaine; Male; Middle Aged; Pilot Projects; Plasma Skin Regeneration; Rhytidoplasty; Single-Blind Method; Skin; Tetracaine; Time Factors; Young Adult	2014
Efficacy of Benzocaine 20% Topical Anesthetic Compared to Placebo Prior to Administration of Local Anesthesia in the Oral Cavity: A Randomized Controlled Trial. Anesthesia progress, 2015,Summer, Volume: 62, Issue:2 Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Local; Benzocaine; Double-Blind Method; Female; Humans; Injections; Lidocaine; Male; Maxillary Nerve; Middle Aged; Needles; Nerve Block; Pain Measurement; Pain Perception; Palate; Placebos; Young Adult	2015
Evaluation of 2-Stage Injection Technique in Children. Anesthesia progress, 2016,Spring, Volume: 63, Issue:1 Topics: Administration, Buccal; Adolescent; Anesthesia, Dental; Anesthetics, Local; Benzocaine; Child; Child Behavior; Cross-Over Studies; Humans; Injections; Lidocaine; Mandibular Nerve; Maxillary Nerve; Needles; Nerve Block; Pain; Pain Measurement; Pain Perception	2016
Clinical Comparison: Fast-Acting and Traditional Topical Dental Anesthetic. Anesthesia progress, 2016,Summer, Volume: 63, Issue:2 Topics: Adult; Aged; Anesthesia, Dental; Anesthetics; Anesthetics, Local; Benzocaine; Cross-Over Studies; Cryoanesthesia; Drug Combinations; Female; Gels; Humans; Hydrocarbons, Fluorinated; Injections; Lidocaine; Male; Middle Aged; Pain Measurement; Time Factors; Young Adult	2016
Effect of Topical Anesthesia with Lidocaine-prilocaine (EMLA) Cream and Local Pressure on Pain during Infiltration Injection for Maxillary Canines: A Randomized Double-blind clinical trial. The journal of contemporary dental practice, 2016, Jul-01, Volume: 17, Issue:7 Topics: Administration, Topical; Adult; Anesthesia, Local; Anesthetics, Local; Benzocaine; Cuspid; Double-Blind Method; Female; Healthy Volunteers; Humans; Injections; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Maxilla; Pain Management; Pain Measurement; Pressure; Prilocaine; Treatment Outcome	2016
Topical Transdermally Delivered Lidocaine and Benzocaine Compared to Compounded Lidocaine/Tetracaine During Microfocused Ultrasound With Visualization Treatment. Journal of drugs in dermatology : JDD, 2018, Jul-01, Volume: 17, Issue:7 Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Benzocaine; Double-Blind Method; Drug Combinations; Female; Humans; Lidocaine; Male; Middle Aged; Pain Measurement; Pain, Procedural; Patient Satisfaction; Rhytidoplasty; Skin Aging; Tetracaine; Treatment Outcome; Ultrasonic Therapy; Young Adult	2018
Efficacy of Topical Benzocaine in Maxilla: A Randomized Controlled Trial. Anesthesia progress, 2019,Spring, Volume: 66, Issue:1 Topics: Administration, Topical; Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Benzocaine; Female; Humans; Injections; Lidocaine; Male; Maxilla; Pain Measurement	2019
Comparing the Efficacy of a Compound Topical Anesthetic Versus Benzocaine: A Pilot Study. Anesthesia progress, 2020,Spring, Volume: 67, Issue:1 Topics: Anesthetics, Local; Benzocaine; Double-Blind Method; Humans; Lidocaine; Pain Measurement; Pilot Projects; Prilocaine; Prospective Studies	2020
Evaluating the Preemptive Analgesic Effect of Photo-biomodulation Therapy on Pain Perception During Local Anesthesia Injection in Children: A Split-mouth Triple-blind Randomized Controlled Clinical Trial. Photochemistry and photobiology, 2022, Volume: 98, Issue:5 Topics: Analgesics; Anesthesia, Local; Anesthetics, Local; Benzocaine; Child; Gels; Humans; Lidocaine; Mouth; Pain; Pain Measurement; Pain Perception	2022

Other Studies

127 other study(ies) available for benzocaine and lidocaine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4 Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity	2004
Molecular characteristics for solid-state limited solubility. Journal of medicinal chemistry, 2008, May-22, Volume: 51, Issue:10 Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Ligand-based design and synthesis of novel sodium channel blockers from a combined phenytoin-lidocaine pharmacophore. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Drug Design; Expert Systems; Inhibitory Concentration 50; Lidocaine; Ligands; Models, Molecular; Phenytoin; Sodium Channel Blockers; Structure-Activity Relationship	2009
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands. Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1 Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels	2014
Estimation of the lipophilicity of purine-2,6-dione-based TRPA1 antagonists and PDE4/7 inhibitors with analgesic activity. Bioorganic & medicinal chemistry letters, 2021, 10-01, Volume: 49 Topics: Analgesics; Benzeneacetamides; Cyclic Nucleotide Phosphodiesterases, Type 7; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Phenylbutyrates; Phosphodiesterase 4 Inhibitors; Principal Component Analysis; Quantitative Structure-Activity Relationship; TRPA1 Cation Channel; Xanthines	2021
The pH-dependent rate of action of local anesthetics on the node of Ranvier. The Journal of general physiology, 1977, Volume: 69, Issue:4 Topics: Anesthetics, Local; Animals; Anura; Benzocaine; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; In Vitro Techniques; Lidocaine; Potassium; Procaine; Rana pipiens; Ranvier's Nodes; Receptors, Drug; Sodium; Tetracaine	1977
Local anesthetics. Effect of pH on use-dependent block of sodium channels in frog muscle. Biophysical journal, 1977, Volume: 20, Issue:3 Topics: Anesthetics, Local; Animals; Anura; Benzocaine; Biological Transport, Active; Hydrogen-Ion Concentration; Kinetics; Lidocaine; Muscles; Procaine; Rana pipiens; Rana temporaria; Sodium	1977
Inhibition of axonal transport in nerves chronically treated with local anesthetics. Experimental neurology, 1975, Volume: 47, Issue:3 Topics: Anesthetics, Local; Animals; Axonal Transport; Benzocaine; Bupivacaine; Catecholamines; Cholinesterases; Depression, Chemical; Female; Leucine; Lidocaine; Male; Motor Neurons; Nerve Block; Neural Conduction; Neurons; Procaine; Rats; Sciatic Nerve; Tritium	1975
Comparison of pharmacological effects of some local anaesthetic agents when using water and lipid emulsion as injection vehicles. Acta pharmacologica et toxicologica, 1975, Volume: 36, Issue:4 Topics: 4-Aminobenzoic Acid; Anesthetics, Local; Anilides; Animals; Benzocaine; Depression, Chemical; Emulsions; Heart; Lidocaine; Male; Mice; Muscle Contraction; Pharmaceutical Vehicles; Rats; Water	1975
Mechanism of action of local anaesthetic agents and biotoxins. British journal of anaesthesia, 1975, Volume: 47 suppl Topics: Acetylcholine; Action Potentials; Anesthetics, Local; Animals; Benzocaine; Binding Sites; Binding, Competitive; Calcium; Cell Membrane; Fishes; Humans; Hydrogen-Ion Concentration; Lidocaine; Membrane Potentials; Neural Conduction; Potassium; Procaine; Rabbits; Saxitoxin; Sodium; Structure-Activity Relationship; Surface Properties; Tetrodotoxin; Toxins, Biological	1975
Voltage-dependent and voltage-independent blockade of acetylcholine receptors by local anesthetics in Electrophorus electroplaques. Molecular pharmacology, 1979, Volume: 15, Issue:3 Topics: Acetylcholine; Anesthetics, Local; Animals; Benzocaine; Chlorpromazine; Dibucaine; Electric Conductivity; Electric Organ; Electrophorus; In Vitro Techniques; Kinetics; Lidocaine; Membrane Potentials; Procaine; Receptors, Cholinergic; Receptors, Nicotinic; Tetracaine	1979
Local Anesthetics: do benzocaine and lidocaine act at the same single site? The Journal of general physiology, 1978, Volume: 71, Issue:2 Topics: Animals; Anura; Benzocaine; Lidocaine; Peripheral Nerves; Receptors, Drug	1978
Cell shape changes induced by cationic anesthetics. The Journal of experimental medicine, 1976, Feb-01, Volume: 143, Issue:2 Topics: Anesthetics, Local; Animals; Benzocaine; Cell Adhesion; Cell Fusion; Cell Membrane; Cell Movement; Chlorpromazine; Culture Media; Dibucaine; Edetic Acid; Egtazic Acid; Female; HEPES; Lidocaine; Macrophages; Mice; Prilocaine; Pseudopodia; Structure-Activity Relationship; Tetracaine; Tetrodotoxin; Tromethamine	1976
Pressure antagonism to nerve conduction block by anesthetic agents. Anesthesiology, 1977, Volume: 47, Issue:1 Topics: Anesthetics; Anesthetics, Local; Animals; Atmospheric Pressure; Benzocaine; Cell Membrane; Halothane; Lidocaine; Male; Methoxyflurane; Neural Conduction; Procaine; Rats; Sympathetic Nervous System; Tetrodotoxin	1977
The appendix of the ventricle of the larynx. Radiology, 1976, Volume: 120, Issue:3 Topics: Anesthesia, Local; Benzocaine; Fluoroscopy; Humans; Laryngeal Diseases; Laryngeal Neoplasms; Larynx; Lidocaine; Vocal Cords	1976
Utilizing local spray intubation. AANA journal, 1975, Volume: 43, Issue:2 Topics: Anesthetics, Local; Benzocaine; Drug Combinations; Intubation, Intratracheal; Lidocaine	1975
Contact urticaria syndrome. Contact urticaria to diethyltoluamide (immediate-type hypersensitivity). Archives of dermatology, 1975, Volume: 111, Issue:6 Topics: Adult; Ammonium Sulfate; Atropine; Benzamides; Benzocaine; Chlorpheniramine; DEET; Dermatitis, Contact; Diphenhydramine; Female; Histamine; Humans; Hypersensitivity, Immediate; Insect Repellents; Lidocaine; p-Methoxy-N-methylphenethylamine; Patch Tests; Urticaria	1975
The chemistry of local anaesthetic agents: classification of blocking agents. British journal of anaesthesia, 1975, Volume: 47 suppl Topics: Anesthetics, Local; Benzocaine; Benzyl Compounds; Binding Sites; Binding, Competitive; Cell Membrane; Lidocaine; Models, Molecular; Neural Conduction; Neurilemma; Phenobarbital; Phenols; Saxitoxin; Sodium; Structure-Activity Relationship; Succinimides; Tetrodotoxin	1975
Blockade by local anaesthetics of the single Ca(2+)-activated K+ channel in rat hippocampal neurones. British journal of pharmacology, 1992, Volume: 105, Issue:1 Topics: Anesthetics, Local; Animals; Benzocaine; Calcium; Female; Hippocampus; In Vitro Techniques; Lidocaine; Male; Neurons; Potassium Channels; Rats; Rats, Inbred Strains	1992
Topical anesthetic-induced methemoglobinemia in sheep: a comparison of benzocaine and lidocaine. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 18, Issue:2 Topics: Administration, Topical; Anesthesia; Animals; Benzocaine; Dose-Response Relationship, Drug; Female; Hemoglobins; Lidocaine; Methemoglobin; Methemoglobinemia; Propiophenones; Radiation-Protective Agents; Sheep	1992
Phonophoresis: an in vivo evaluation using three topical anaesthetic preparations. Ultrasonics, 1990, Volume: 28, Issue:3 Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Benzocaine; Dibucaine; Drug Combinations; Electric Conductivity; Electric Stimulation; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Nociceptors; Phonophoresis; Prilocaine; Sensory Thresholds; Skin	1990
Pain relief in hysterosalpingography. A comparison of analgesics. The Journal of reproductive medicine, 1990, Volume: 35, Issue:5 Topics: Analgesics; Benzocaine; Dose-Response Relationship, Drug; Drug Combinations; Female; Gels; Humans; Hysterosalpingography; Lidocaine; Naproxen; Pain	1990
Different effects of local anesthetics on calcium influx into rat mast cells. General pharmacology, 1985, Volume: 16, Issue:3 Topics: Anesthetics, Local; Animals; Benzocaine; Biological Transport; Calcium; Histamine Release; In Vitro Techniques; Lidocaine; Male; Mast Cells; Membranes, Artificial; Procaine; Rats; Rats, Inbred Strains	1985
Interaction of lidocaine and benzocaine in depressing Vmax of ventricular action potentials. Journal of molecular and cellular cardiology, 1985, Volume: 17, Issue:5 Topics: Action Potentials; Animals; Benzocaine; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Guinea Pigs; In Vitro Techniques; Ion Channels; Lidocaine; Osmolar Concentration; Papillary Muscles; Temperature	1985
Properties of the sodium gating current in the squid giant axon. Annals of the New York Academy of Sciences, 1986, Volume: 479 Topics: Anesthetics, Local; Animals; Axons; Benzocaine; Ion Channels; Lidocaine; Membrane Potentials; Neural Conduction; Sodium; Tetrodotoxin	1986
Weak bases mimic the fertilization-associated chloride conductance increase and induce morphological changes in the cortex of Xenopus laevis eggs. Cell differentiation and development : the official journal of the International Society of Developmental Biologists, 1989, Volume: 26, Issue:1 Topics: Ammonia; Animals; Benzocaine; Calcium; Cell Membrane Permeability; Chlorides; Female; Fertilization; Hydrogen-Ion Concentration; Ion Channels; Lidocaine; Male; Membrane Potentials; Methylamines; Microscopy, Electron; Microscopy, Electron, Scanning; Microvilli; Oocytes; Procaine; Xenopus laevis	1989
[In vitro microbiological research on oral ointments]. Zahn-, Mund-, und Kieferheilkunde mit Zentralblatt, 1989, Volume: 77, Issue:4 Topics: Administration, Topical; Anti-Infective Agents, Local; Bacteria; Benzocaine; Candida albicans; Drug Combinations; Humans; Lidocaine; Microbial Sensitivity Tests; Mouth; Ointments	1989
Pituitary thyrotropin-releasing hormone receptors: local anesthetic effects on binding and responses. Molecular endocrinology (Baltimore, Md.), 1989, Volume: 3, Issue:9 Topics: Anesthetics, Local; Animals; Benzocaine; Chlordiazepoxide; Chlorpromazine; Dibucaine; Hydrogen-Ion Concentration; Imipramine; Lidocaine; Pituitary Gland; Procaine; Prolactin; Propranolol; Rats; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Tetracaine; Thyrotropin-Releasing Hormone; Trifluoperazine; Verapamil	1989
Severe methaemoglobinaemia after flexible fibreoptic bronchoscopy. Thorax, 1989, Volume: 44, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Adult; Benzocaine; Bronchoscopy; Fiber Optic Technology; Humans; Lidocaine; Male; Methemoglobinemia; Methylene Blue	1989
Effects of topical anesthetic agents on Campylobacter pylori. Journal of pediatric gastroenterology and nutrition, 1989, Volume: 9, Issue:1 Topics: Administration, Topical; Anti-Bacterial Agents; Benzocaine; Campylobacter; Campylobacter Infections; Endoscopy; Gastrointestinal Diseases; Humans; Lidocaine	1989
Dual effect of local anesthetics on the function of excitable rod outer segment disk membrane. Anesthesiology, 1986, Volume: 64, Issue:4 Topics: Anesthetics, Local; Animals; Benzocaine; Bupivacaine; Calcium; Cattle; Dibucaine; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; In Vitro Techniques; Lidocaine; Light; Photoreceptor Cells; Protons; Rhodopsin; Rod Cell Outer Segment; Tetracaine	1986
Anaesthesia of the medicinal leech (Hirudo medicinalis). The Veterinary record, 1986, May-24, Volume: 118, Issue:21 Topics: Anesthesia; Animals; Benzocaine; Carbon Dioxide; Leeches; Lidocaine	1986
Reduction of Vmax by QX-314 and benzocaine in neonatal and adult canine cardiac Purkinje fibers. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1 Topics: Action Potentials; Animals; Animals, Newborn; Benzocaine; Dogs; Heart Conduction System; Kinetics; Lidocaine; Membrane Potentials; Purkinje Fibers	1988
Acquired methemoglobinemia. A case report. Missouri medicine, 1987, Volume: 84, Issue:4 Topics: Aged; Aged, 80 and over; Benzocaine; Female; Humans; Lidocaine; Methemoglobinemia	1987
pH-dependent effects of local anaesthetics in perturbing lipid membranes. General physiology and biophysics, 1987, Volume: 6, Issue:3 Topics: Anesthetics, Local; Animals; Benzocaine; Brain; Carbamates; Cattle; Hydrogen-Ion Concentration; In Vitro Techniques; Lidocaine; Membrane Lipids; Phosphatidylcholines	1987
Structure/nerve membrane effect relationships of some local anaesthetics. General physiology and biophysics, 1986, Volume: 5, Issue:4 Topics: Action Potentials; Anesthetics, Local; Animals; Benzocaine; Electrons; Lidocaine; Membrane Potentials; Procaine; Rana ridibunda; Sciatic Nerve; Structure-Activity Relationship; Tetracaine; Water	1986
Topical anesthetics: use and misuse. Southern medical journal, 1985, Volume: 78, Issue:10 Topics: Aerosols; Anesthetics, Local; Benzocaine; Humans; Lidocaine; Mouthwashes; Ointments; Powders; Propiophenones; Propoxycaine; Suppositories; Tablets; Tetracaine; Tripelennamine	1985
Effects of local anaesthetics on prostaglandin biosynthesis in vitro. Biochimica et biophysica acta, 1974, Sep-19, Volume: 360, Issue:3 Topics: 4-Aminobenzoic Acid; Anesthetics, Local; Animals; Benzocaine; Calcium; Carbon Radioisotopes; Cattle; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Dibucaine; Edetic Acid; Kinetics; Lidocaine; Linoleic Acids; Male; Mepivacaine; Oleic Acids; Phosphatidylethanolamines; Phospholipases; Procaine; Prostaglandins; Seminal Vesicles; Sheep; Snakes; Species Specificity; Tetracaine; Triglycerides	1974
A modification of a method for the evaluation of topical anaesthesia in the earthworm. The Journal of pharmacy and pharmacology, 1967, Volume: 19, Issue:7 Topics: Anesthesia, Local; Anesthetics, Local; Animals; Annelida; Benzocaine; Hydrochloric Acid; Lidocaine; Solutions	1967
[Relationship between chemical structure, physio-chemical properties, chemical reactivity and effect of various local anesthetics with position isomerism. 31. 1]. Arzneimittel-Forschung, 1974, Volume: 24, Issue:12 Topics: Acetanilides; Anesthesia, Conduction; Anesthesia, Local; Anesthetics, Local; Animals; Anthelmintics; Benzocaine; Binding Sites; Blood Pressure; Chemical Phenomena; Chemistry; Cocaine; Diphenhydramine; Ethylamines; Hydroxides; Isomerism; Lethal Dose 50; Lidocaine; Mice; Procaine; Propylamines; Quaternary Ammonium Compounds; Rabbits; Rats; Structure-Activity Relationship; Sulfanilamides	1974
Local anesthesia and experimental epilepsy. Epilepsia, 1974, Volume: 15, Issue:2 Topics: Animals; Benzocaine; Cats; Disease Models, Animal; Female; Lidocaine; Male; Procaine; Seizures; Time Factors	1974
A "neutral" local anesthetic for reasearch in experimental epilepsy. T.-I.-T. journal of life sciences, 1974, Volume: 4, Issue:1 Topics: Anesthetics, Local; Animals; Benzocaine; Cats; Cerebral Cortex; Electric Stimulation; Evoked Potentials; Lidocaine; Procaine; Seizures	1974
Local anesthetics: effects on permeability properties of nodal membrane in myelinated nerve fibres from xenopus. Potential clamp experiments. Acta physiologica Scandinavica, 1974, Volume: 91, Issue:1 Topics: Anesthetics, Local; Animals; Benzocaine; Calcium; Cell Membrane Permeability; Depression, Chemical; Hydrogen-Ion Concentration; Lidocaine; Membrane Potentials; Nerve Fibers, Myelinated; Potassium; Procaine; Sodium; Xenopus	1974
Pancreatic secretion after selective and truncal vagotomy in the dog. The British journal of surgery, 1971, Volume: 58, Issue:11 Topics: Benzocaine; Bicarbonates; Cholecystokinin; Eating; Hydrogen-Ion Concentration; Intubation, Gastrointestinal; Lidocaine; Pancreatic Juice; Proteins; Reflex; Secretin; Vagotomy	1971
Local anesthetics: effect of pH on activity. Science (New York, N.Y.), 1968, Dec-20, Volume: 162, Issue:3860 Topics: Action Potentials; Animals; Benzocaine; Chemical Phenomena; Chemistry, Physical; Depression, Chemical; Dibucaine; Hydrogen-Ion Concentration; In Vitro Techniques; Lidocaine; Neural Conduction; Neurons; Rabbits; Vagus Nerve	1968
In vivo evaluation of local anesthetics applied topically. Journal of pharmaceutical sciences, 1968, Volume: 57, Issue:12 Topics: Animals; Benzocaine; Burns; Eye; Guinea Pigs; Lidocaine; Propylene Glycols; Rabbits; Skin Diseases	1968
[Relations between chemical constitution, physico-chemical properties, chemical reactivity and local anesthetic effect in the iso-procaine series. 24]. Arzneimittel-Forschung, 1969, Volume: 19, Issue:4 Topics: Amino Alcohols; Aminobenzoates; Anesthetics, Local; Benzocaine; Chemical Phenomena; Chemistry, Physical; Esters; Infrared Rays; Lidocaine; Methylation; Oxidation-Reduction; Procaine; Spectrum Analysis; Tetracaine; Ultraviolet Rays	1969
The effect of local anaesthetics on the components of the asymmetry current in the squid giant axon. The Journal of physiology, 1984, Volume: 352 Topics: Action Potentials; Anesthetics, Local; Animals; Axons; Benzocaine; Decapodiformes; In Vitro Techniques; Ion Channels; Lidocaine; Membrane Potentials; Models, Neurological; Sodium; Time Factors	1984
Interaction of lidocaine and benzocaine in blocking sodium channels. Pflugers Archiv : European journal of physiology, 1980, Volume: 387, Issue:1 Topics: Animals; Benzocaine; Dose-Response Relationship, Drug; Drug Interactions; Ion Channels; Lidocaine; Membrane Potentials; Nerve Fibers, Myelinated; Rana esculenta; Ranvier's Nodes; Receptors, Drug	1980
Local anesthetics QX 572 and benzocaine act at separate sites on the batrachotoxin-activated sodium channel. The Journal of general physiology, 1981, Volume: 77, Issue:2 Topics: Anesthetics, Local; Animals; Batrachotoxins; Benzocaine; Binding Sites; Drug Interactions; Ion Channels; Kinetics; Lidocaine; Mice; Models, Biological; Sodium	1981
Voltage- and use-dependent effects of lidocaine on sodium current in rat single ventricular cells. Circulation research, 1983, Volume: 52, Issue:5 Topics: Animals; Benzocaine; Electrophysiology; Female; Heart Ventricles; Ion Channels; Lidocaine; Rats	1983
The influence of molecular form of local anesthetic-type antiarrhythmic agents on reduction of the maximum upstroke velocity of canine cardiac Purkinje fibers. Circulation research, 1983, Volume: 52, Issue:6 Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Benzocaine; Dogs; Heart Conduction System; Ion Channels; Lidocaine; Membrane Potentials; Molecular Conformation; Purkinje Fibers; Sodium; Tocainide	1983
[Topical anesthetic effects of ethylaminobenzoate on the blink reflex of the cornea of male guinea pigs and on human gingiva]. Josai Shika Daigaku kiyo. The Bulletin of the Josai Dental University, 1983, Volume: 12, Issue:1 Topics: Administration, Topical; Animals; Benzocaine; Blinking; Cornea; Gingiva; Guinea Pigs; Humans; Lidocaine	1983
Local anesthetics. Annals of dentistry, 1983,Summer, Volume: 42, Issue:1 Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Benzocaine; Child; Child, Preschool; Epinephrine; Humans; Lidocaine; Mepivacaine; Prilocaine; Procaine; Tetracaine	1983
Magnesium enhances local anesthetic nerve block of frog sciatic nerve. Anesthesia and analgesia, 1984, Volume: 63, Issue:2 Topics: Action Potentials; Anesthetics, Local; Animals; Benzocaine; Calcium; Drug Synergism; In Vitro Techniques; Lidocaine; Magnesium; Nerve Block; Rana pipiens; Sciatic Nerve	1984
Topical anesthesia for nasogastric tube placement. Annals of emergency medicine, 1982, Volume: 11, Issue:11 Topics: 4-Aminobenzoic Acid; Administration, Topical; Anesthesia, Local; Benzalkonium Compounds; Benzocaine; Cetrimonium Compounds; Drug Combinations; Humans; Intubation, Gastrointestinal; Lidocaine; Male; para-Aminobenzoates; Tetracaine	1982
The effect of local anaesthetics and antiarrhythmic agents on the responses of rabbit platelete to ADP and thrombin. Thrombosis and haemostasis, 1981, Feb-23, Volume: 45, Issue:1 Topics: Anesthetics, Local; Animals; Benzocaine; Blood Platelets; Calcium; Dose-Response Relationship, Drug; In Vitro Techniques; Lidocaine; Platelet Aggregation; Procaine; Propranolol; Quinidine; Rabbits; Tetracaine	1981
Cholesterol esterification by rat adrenal gland. Inhibition by local anesthetics in vitro. Biochimica et biophysica acta, 1981, Oct-23, Volume: 666, Issue:1 Topics: Acyl Coenzyme A; Acyltransferases; Adrenal Glands; Anesthetics, Local; Animals; Benzocaine; Cholesterol Esters; Dibucaine; Lidocaine; Male; Oleic Acids; Rats; Sterol O-Acyltransferase; Tetracaine	1981
[Influence of Pluronic F 68 on the absorption of benzocaine and lidocaine by fish (author's transl)]. Archiv der Pharmazie, 1981, Volume: 314, Issue:11 Topics: Absorption; Animals; Benzocaine; Fishes; Lidocaine; Poloxalene; Polyethylene Glycols	1981
Allergic reactions to topical (surface) anesthetics with reference to the safety of tronothane (pramoxine hydrochloride). Cutis, 1980, Volume: 25, Issue:6 Topics: Administration, Topical; Anesthetics; Anti-Inflammatory Agents; Benzocaine; Dermatitis; Dermatitis, Contact; Humans; Hydrocortisone; Hydroxybenzoates; Lidocaine; Morpholines; Ointments; Piperidines; Safety	1980
Acute methemoglobinemia induced by topical benzocaine and lidocaine. Archives of internal medicine, 1980, Volume: 140, Issue:11 Topics: Adult; Benzocaine; Humans; Lidocaine; Male; Methemoglobinemia	1980
Contrasting actions of cocaine, local anaesthetic and tetrodotoxin on discharge properties of rat aortic baroreceptors. The Journal of physiology, 1994, Jun-01, Volume: 477, Issue:Pt 2 Topics: Anesthetics, Local; Animals; Aorta, Thoracic; Benzocaine; Cocaine; Dose-Response Relationship, Drug; In Vitro Techniques; Lidocaine; Male; Pressoreceptors; Pressure; Rats; Rats, Sprague-Dawley; Sodium Channels; Tetrodotoxin	1994
Methemoglobinemia from topically applied anesthetic spray. Mayo Clinic proceedings, 1994, Volume: 69, Issue:9 Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Local; Benzocaine; Female; Humans; Lidocaine; Male; Methemoglobinemia; Middle Aged	1994
Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study. The Journal of general physiology, 1994, Volume: 103, Issue:1 Topics: Animals; Benzocaine; Dogs; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Kinetics; Lidocaine; Myocardium; Purkinje Fibers; Saxitoxin; Sodium Channels	1994
Effects of local anaesthetics on retinal spreading depression. Experimental brain research, 1993, Volume: 96, Issue:2 Topics: Animals; Benzocaine; Chickens; Dose-Response Relationship, Drug; Evoked Potentials; In Vitro Techniques; Lidocaine; Retina	1993
Delayed-type hypersensitivity to subcutaneous lidocaine with tolerance to articaine: confirmation by in vivo and in vitro tests. Contact dermatitis, 1996, Volume: 34, Issue:6 Topics: Adult; Anesthetics, Local; Benzocaine; Bupivacaine; Carticaine; Cross Reactions; Dermatitis, Allergic Contact; Dibucaine; Drug Eruptions; Drug Tolerance; Eczema; Edema; Female; Humans; Hypersensitivity, Delayed; Injections, Subcutaneous; Lidocaine; Lymphocyte Activation; Mepivacaine; Parabens; Patch Tests; Preservatives, Pharmaceutical; Prilocaine; Procaine; Quinolines; Recurrence; Skin Tests; Sulfites; Tetracaine	1996
Capillary gas chromatographic method for the determination of n-butyl-p-aminobenzoate and lidocaine in plasma samples. Journal of chromatography. B, Biomedical applications, 1995, Nov-03, Volume: 673, Issue:1 Topics: Anesthetics, Local; Animals; Benzocaine; Blood Specimen Collection; Calibration; Cholinesterase Inhibitors; Chromatography, Gas; Dogs; Drug Stability; Humans; Injections, Epidural; Isoflurophate; Lidocaine; Reproducibility of Results; Sensitivity and Specificity	1995
[Clinical study of patients with positive reactions in patch tests with local anesthetics]. Nihon Ika Daigaku zasshi, 1997, Volume: 64, Issue:2 Topics: Anesthetics, Local; Benzocaine; Cross Reactions; Dermatitis, Allergic Contact; Dibucaine; Humans; Lidocaine; Patch Tests; Procaine	1997
A common local anesthetic receptor for benzocaine and etidocaine in voltage-gated mu1 Na+ channels. Pflugers Archiv : European journal of physiology, 1998, Volume: 435, Issue:2 Topics: Amino Acid Sequence; Anesthetics, Local; Benzocaine; Cell Line; Electric Conductivity; Embryo, Mammalian; Etidocaine; Humans; Kidney; Lidocaine; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Drug; Sodium Channels	1998
Local anesthetic block of batrachotoxin-resistant muscle Na+ channels. Molecular pharmacology, 1998, Volume: 54, Issue:2 Topics: Anesthetics, Local; Batrachotoxins; Benzocaine; Cells, Cultured; Drug Resistance; Etidocaine; Humans; Lidocaine; Muscles; Sodium Channels	1998
Effects of local anesthetics on Na+ channels containing the equine hyperkalemic periodic paralysis mutation. The American journal of physiology, 1998, Volume: 275, Issue:2 Topics: Anesthetics, Local; Animals; Benzocaine; Electrophysiology; Female; Horse Diseases; Horses; Hyperkalemia; In Vitro Techniques; Lidocaine; Membrane Potentials; Mexiletine; Mutagenesis, Site-Directed; Oocytes; Paralyses, Familial Periodic; Point Mutation; Rats; Sodium Channels; Xenopus laevis	1998
The action of local anaesthetics on the compound action potential is altered by the nature of the permeant ion in frog nerve. Neuroscience letters, 1998, Aug-07, Volume: 252, Issue:1 Topics: Action Potentials; Anesthetics, Local; Animals; Benzocaine; Dose-Response Relationship, Drug; Lidocaine; Lithium; Procaine; Rana pipiens; Rana temporaria; Sciatic Nerve; Sodium; Sodium Channels; Tetrodotoxin	1998
Synergistic inhibition of lysophosphatidic acid signaling by charged and uncharged local anesthetics. Anesthesia and analgesia, 1999, Volume: 88, Issue:5 Topics: Anesthetics, Local; Animals; Benzocaine; Chloride Channels; Dose-Response Relationship, Drug; Female; Guanosine 5'-O-(3-Thiotriphosphate); Lidocaine; Lysophospholipids; Protein Kinase C; Signal Transduction; Xenopus	1999
Local anesthetic anchoring to cardiac sodium channels. Implications into tissue-selective drug targeting. Circulation research, 1999, Jul-09, Volume: 85, Issue:1 Topics: Anesthetics, Local; Animals; Benzocaine; Binding Sites; Drug Combinations; Female; Humans; Lidocaine; Male; Mesylates; Myocardium; Oocytes; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channels; Xenopus laevis	1999
Use of the intubating laryngeal mask airway to facilitate awake orotracheal intubation in patients with cervical spine disorders. Journal of clinical anesthesia, 1999, Volume: 11, Issue:4 Topics: Administration, Topical; Adult; Aerosols; Anesthetics, Local; Benzocaine; Bronchoscopes; Cervical Vertebrae; Female; Fiber Optic Technology; Humans; Intervertebral Disc Displacement; Intubation, Intratracheal; Laryngeal Masks; Lidocaine; Middle Aged; Neurologic Examination; Posture; Spinal Diseases; Spinal Fractures; Wakefulness	1999
Comparison of 4 topical anesthetic agents for effect and corneal toxicity in rabbits. Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:9 Topics: Anesthetics, Local; Animals; Benzocaine; Bupivacaine; Cornea; Epithelium, Corneal; Female; Hydrogen-Ion Concentration; Lidocaine; Male; Ophthalmic Solutions; Procaine; Rabbits; Random Allocation; Sensation; Wound Healing	1999
Four types of topical anaesthetic agents: evaluation of clinical effectiveness. The Journal of clinical pediatric dentistry, 1999,Spring, Volume: 23, Issue:3 Topics: Administration, Topical; Adolescent; Anesthesia, Dental; Anesthetics, Local; Benzocaine; Child; Dibucaine; Evaluation Studies as Topic; Facial Pain; Female; Gels; Humans; Injections; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Pain Measurement; Prilocaine; Tetracaine	1999
Acquired allergic reaction to topical anesthesia--a case report. The New York state dental journal, 1999, Volume: 65, Issue:10 Topics: Adult; Anesthetics, Local; Benzocaine; Diagnosis, Differential; Drug Eruptions; Exanthema; Female; Humans; Lidocaine; Lip Diseases; Mepivacaine; Mouth Diseases	1999
Selective block of late Na(+) current by local anaesthetics in rat large sensory neurones. British journal of pharmacology, 2000, Volume: 129, Issue:8 Topics: Anesthetics, Local; Animals; Benzocaine; Cells, Cultured; Electrophysiology; Lidocaine; Male; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium Channel Blockers	2000
Methemoglobinemia after topical anesthesia with lidocaine and benzocaine for a difficult intubation. Journal of clinical anesthesia, 2000, Volume: 12, Issue:2 Topics: Adult; Anesthesia, Local; Anesthetics, Local; Benzocaine; Carbon Dioxide; Enzyme Inhibitors; Female; Fiber Optic Technology; Humans; Intubation, Intratracheal; Lidocaine; Methemoglobinemia; Methylene Blue; Oxygen	2000
Local anesthetic inhibition of m1 muscarinic acetylcholine signaling. Anesthesiology, 2000, Volume: 93, Issue:2 Topics: Acetylcholine; Anesthetics, Local; Animals; Benzocaine; Binding Sites; Cells, Cultured; CHO Cells; Choline; Cricetinae; Electrophysiology; GTP-Binding Proteins; Lidocaine; Patch-Clamp Techniques; Quinuclidinyl Benzilate; Receptors, Muscarinic; Signal Transduction; Xenopus	2000
Diffusion of n-butyl-p-aminobenzoate (BAB), lidocaine and bupivacaine through the human dura-arachnoid mater in vitro. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2000, Volume: 12, Issue:2 Topics: Anesthetics, Local; Arachnoid; Benzocaine; Bupivacaine; Diffusion; Dura Mater; Humans; In Vitro Techniques; Kinetics; Lidocaine; Spinal Cord	2000
Placement of the esophageal Doppler ultrasound monitor probe in awake patients. Chest, 2001, Volume: 119, Issue:1 Topics: Anesthesia, Local; Benzocaine; Conscious Sedation; Echocardiography, Transesophageal; Humans; Lidocaine	2001
Drug-induced methemoglobinemia during thoracoscopic lung biopsy. The Annals of thoracic surgery, 2001, Volume: 71, Issue:2 Topics: Aerosols; Benzocaine; Bronchiolitis Obliterans; Gels; Humans; Intraoperative Complications; Lidocaine; Lung; Male; Methemoglobinemia; Middle Aged; Thoracoscopy	2001
Inhibition of m3 muscarinic acetylcholine receptors by local anaesthetics. British journal of pharmacology, 2001, Volume: 133, Issue:1 Topics: Anesthetics, Local; Animals; Benzocaine; CHO Cells; Cricetinae; Female; Heterotrimeric GTP-Binding Proteins; Inhibitory Concentration 50; Lidocaine; Models, Biological; Muscarinic Antagonists; Oocytes; Rats; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptors, Muscarinic; Signal Transduction; Xenopus laevis	2001
Perioperatively acquired methaemoglobinaemia in a preterm infant. Paediatric anaesthesia, 2002, Volume: 12, Issue:3 Topics: Anesthetics, Local; Benzocaine; Cyanosis; Diseases in Twins; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Lidocaine; Methemoglobinemia; Methylene Blue	2002
The use of lubricants to achieve tracheal intubation in neonates and infants. Paediatric anaesthesia, 2002, Volume: 12, Issue:8 Topics: Anesthetics, Local; Benzocaine; Cyanosis; Female; Humans; Infant, Newborn; Intubation, Intratracheal; Lidocaine; Lubrication; Methemoglobinemia	2002
CLINICAL EFFECTIVENESS OF DRUGS USED FOR TOPICAL ANESTHESIA. JAMA, 1964, May-25, Volume: 188 Topics: Anesthesia, Local; Anesthetics; Anesthetics, Local; Benzocaine; Cocaine; Dibucaine; Electric Stimulation; Humans; Lidocaine; Lip; Mepivacaine; Mucous Membrane; Palate; Pharmacology; Procaine; Sympathomimetics; Tetracaine; Tongue; Treatment Outcome; Tripelennamine	1964
[Identification and determination of lidocaine. Its differentiation from acetanilide, procaine, benzocaine, amylocaine]. Bollettino chimico farmaceutico, 1960, Volume: 99 Topics: Acetanilides; Anesthetics; Anesthetics, Local; Benzoates; Benzocaine; Humans; Lidocaine; Procaine	1960
Analgesic synergy between topical morphine and butamben in mice. Anesthesia and analgesia, 2003, Volume: 97, Issue:4 Topics: Administration, Topical; Analgesics, Opioid; Anesthetics, Local; Animals; Benzocaine; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Lidocaine; Male; Mice; Mice, Inbred ICR; Morphine; Pain Measurement; Reaction Time	2003
Colorimetric determination of benzocaine, lignocaine and procaine hydrochlorides in pure form and in pharmaceutical formulations using p-benzoquinone. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2003, Volume: 19, Issue:10 Topics: Anesthetics, Local; Benzocaine; Benzoquinones; Calorimetry; Chemistry, Pharmaceutical; Drug Compounding; Lidocaine; Pharmaceutical Preparations; Procaine	2003
Influence of liposomal local anesthetics on platelet aggregation in vitro. Journal of liposome research, 2004, Volume: 14, Issue:1-2 Topics: Adenosine Diphosphate; Anesthetics, Local; Benzocaine; Blood Platelets; Bupivacaine; Dose-Response Relationship, Drug; Drug Delivery Systems; Humans; Lidocaine; Liposomes; Platelet Aggregation	2004
Block of inactivation-deficient Na+ channels by local anesthetics in stably transfected mammalian cells: evidence for drug binding along the activation pathway. The Journal of general physiology, 2004, Volume: 124, Issue:6 Topics: Anesthetics, Local; Animals; Benzocaine; Cell Line; Dose-Response Relationship, Drug; Drug Delivery Systems; Humans; Ion Channel Gating; Kidney; Lidocaine; Membrane Potentials; Muscle Proteins; Rats; Sodium Channels; Structure-Activity Relationship; Transfection	2004
Effects of tramadol on nerve action potentials in rat: comparisons with benzocaine and lidocaine. The International journal of neuroscience, 2005, Volume: 115, Issue:3 Topics: Action Potentials; Analgesics, Opioid; Anesthetics, Local; Animals; Benzocaine; Female; Lidocaine; Neural Conduction; Potassium Channels; Rats; Rats, Wistar; Sciatic Nerve; Sodium Channels; Tramadol	2005
Comparison of the effects of four Na+ channel analgesics on TTX-resistant Na+ currents in rat sensory neurons and recombinant Nav1.2 channels. Neuroscience letters, 2006, Mar-13, Volume: 395, Issue:3 Topics: Ambroxol; Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Benzocaine; Drug Resistance; Lidocaine; Mexiletine; NAV1.2 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Neurons, Afferent; Patch-Clamp Techniques; Rats; Recombinant Proteins; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin	2006
Contact urticaria and allergic contact dermatitis to lidocaine in a patient sensitive to benzocaine and propolis. Contact dermatitis, 2006, Volume: 54, Issue:2 Topics: Allergens; Benzocaine; Dermatitis, Allergic Contact; Diagnosis, Differential; Female; Hemorrhoids; Humans; Lidocaine; Middle Aged; Patch Tests; Propolis; Urticaria	2006
Methemoglobinemia after transesophageal echocardiography: a life-threatening complication. Journal of clinical anesthesia, 2006, Volume: 18, Issue:1 Topics: Adult; Anesthetics, Local; Benzocaine; Echocardiography, Transesophageal; Female; Humans; Lidocaine; Male; Methemoglobinemia; Methylene Blue; Middle Aged; Oxidants; Staphylococcal Infections	2006
Interaction of local anesthetics with a peptide encompassing the IV/S4-S5 linker of the Na+ channel. Biophysical chemistry, 2006, Aug-20, Volume: 123, Issue:1 Topics: Amino Acid Sequence; Anesthetics, Local; Benzocaine; Circular Dichroism; Lidocaine; Models, Molecular; Molecular Sequence Data; Peptides; Sodium Channels	2006
Atomic determinants of state-dependent block of sodium channels by charged local anesthetics and benzocaine. FEBS letters, 2006, Nov-13, Volume: 580, Issue:26 Topics: Anesthetics, Local; Benzocaine; Binding Sites; Humans; Lidocaine; Models, Molecular; Molecular Structure; Muscle Proteins; NAV1.5 Voltage-Gated Sodium Channel; Protein Conformation; Sodium; Sodium Channels	2006
Lidocaine alters the input resistance and evokes neural activity in crayfish sensory neurons. General physiology and biophysics, 2007, Volume: 26, Issue:1 Topics: Action Potentials; Animals; Astacoidea; Benzocaine; Dose-Response Relationship, Drug; Electrophysiology; Lidocaine; Mechanoreceptors; Neurons; Patch-Clamp Techniques; Prilocaine; Procaine	2007
Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels. Circulation research, 2008, Jan-04, Volume: 102, Issue:1 Topics: Amino Acids, Aromatic; Anesthetics, Local; Animals; Benzocaine; Binding Sites; Humans; Lidocaine; Muscle Proteins; NAV1.4 Voltage-Gated Sodium Channel; Oocytes; Sodium Channel Blockers; Sodium Channels; Static Electricity; Transfection; Xenopus	2008
Fish skin as a model membrane: structure and characteristics. The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:1 Topics: 2-Hydroxypropyl-beta-cyclodextrin; Algorithms; Animals; Benzocaine; beta-Cyclodextrins; Catfishes; Diethylstilbestrol; Diffusion; Hydrocortisone; In Vitro Techniques; Kinetics; Lidocaine; Membranes; Models, Biological; Naproxen; Nitrates; Permeability; Picrates; Skin; Skin Absorption	2009
Rapid classification of simulated street drug mixtures using Raman spectroscopy and principal component analysis. Applied spectroscopy, 2009, Volume: 63, Issue:7 Topics: Algorithms; Benzocaine; Complex Mixtures; Equipment Design; Illicit Drugs; Lidocaine; Principal Component Analysis; Procaine; Spectrum Analysis, Raman	2009
Using lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity. Circulation research, 2009, Aug-28, Volume: 105, Issue:5 Topics: Anti-Arrhythmia Agents; Benzocaine; Binding Sites; Cell Line; Dose-Response Relationship, Drug; Humans; Ion Channel Gating; Lidocaine; Membrane Potentials; Models, Molecular; Molecular Structure; Muscle Proteins; NAV1.5 Voltage-Gated Sodium Channel; Phenylalanine; Protein Conformation; Protein Structure, Tertiary; Sodium Channels; Transfection	2009
Prevalence of benzocaine and lidocaine patch test sensitivity in Denmark: temporal trends and relevance. Contact dermatitis, 2011, Volume: 65, Issue:2 Topics: Administration, Topical; Anesthetics, Local; Benzocaine; Causality; Denmark; Dermatitis, Allergic Contact; Forecasting; Humans; Lidocaine; Patch Tests; Prevalence; Risk Assessment; Severity of Illness Index	2011
Development, characterization, and in vitro and in vivo evaluation of benzocaine- and lidocaine-loaded nanostructrured lipid carriers. Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:5 Topics: Analgesics; Anesthetics, Local; Animals; Benzocaine; Drug Carriers; Humans; Lidocaine; Lipids; Male; Mice; Nanostructures; Pain; Skin	2011
Long buccal nerve block injection pain in patients with irreversible pulpitis. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2011, Volume: 112, Issue:1 Topics: Adolescent; Adult; Age Factors; Aged; Anesthetics, Local; Benzocaine; Cheek; Epinephrine; Female; Humans; Injections; Lidocaine; Male; Mandible; Mandibular Nerve; Middle Aged; Molar; Needles; Nerve Block; Pain; Pain Measurement; Pulpitis; Sex Factors; Vasoconstrictor Agents; Young Adult	2011
Role of viscosity in influencing the glass-forming ability of organic molecules from the undercooled melt state. Pharmaceutical research, 2012, Volume: 29, Issue:1 Topics: Benzocaine; Calorimetry, Differential Scanning; Crystallization; Dibucaine; Lidocaine; Miconazole; Organic Chemicals; Procaine; Rheology; Thermodynamics; Tolbutamide; Transition Temperature; Viscosity	2012
Relief of palatal injection pain by liposome-encapsulated 2% lignocaine prepared by ultrasonic dental scaler. The British journal of oral & maxillofacial surgery, 2012, Volume: 50, Issue:8 Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Benzocaine; Female; Humans; Injections; Lidocaine; Liposomes; Male; Pain; Pain Measurement; Palate; Tetracaine	2012
Local anesthetic inhibition of a bacterial sodium channel. The Journal of general physiology, 2012, Volume: 139, Issue:6 Topics: Acetanilides; Anesthetics, Local; Bacillus; Benzocaine; Binding Sites; Cell Line, Transformed; Cytoplasm; Eukaryota; HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Kinetics; Lidocaine; Piperazines; Ranolazine; Sodium; Sodium Channels	2012
Extracellular quaternary ammonium blockade of transient receptor potential vanilloid subtype 1 channels expressed in Xenopus laevis oocytes. Molecular pharmacology, 2012, Volume: 82, Issue:6 Topics: Anesthetics, Local; Animals; Benzocaine; Capsaicin; Lidocaine; Mutation; Oocytes; Quaternary Ammonium Compounds; Tetraethylammonium; TRPV Cation Channels; Xenopus laevis; Xenopus Proteins	2012
Potential diversion of local anesthetics from dental offices for use as cocaine adulterants. Journal of the American Dental Association (1939), 2014, Volume: 145, Issue:3 Topics: Anesthetics, Local; Benzocaine; Cocaine-Related Disorders; Dental Offices; Drug Contamination; Humans; Lidocaine; Prescription Drug Diversion	2014
More methemoglobin is produced by benzocaine treatment than lidocaine treatment in human in vitro systems. Regulatory toxicology and pharmacology : RTP, 2014, Volume: 70, Issue:1 Topics: Anesthetics, Local; Aniline Compounds; Benzocaine; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Lidocaine; Liver; Methemoglobin; Methemoglobinemia	2014
Identification of N-Hydroxy-para-aminobenzoic acid in a cyanotic child after benzocaine exposure. Clinical toxicology (Philadelphia, Pa.), 2014, Volume: 52, Issue:9 Topics: 4-Aminobenzoic Acid; Acetaminophen; Administration, Topical; Benzocaine; Bupivacaine; Child; Cyanosis; Dose-Response Relationship, Drug; Humans; Hydroxylamines; Lidocaine; Male; Methemoglobinemia; Methylene Blue; Midazolam; para-Aminobenzoates	2014
Lidocaine contact allergy is becoming more prevalent. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2014, Volume: 40, Issue:12 Topics: Anesthesia, Local; Benzocaine; British Columbia; Dermatitis, Allergic Contact; Drug Hypersensitivity; Female; Humans; Incidence; Lidocaine; Male; Patch Tests; Prevalence	2014
Thin layer chromatography coupled to paper spray ionization mass spectrometry for cocaine and its adulterants analysis. Forensic science international, 2016, Volume: 262 Topics: Benzocaine; Caffeine; Chromatography, Thin Layer; Cocaine; Drug Contamination; Humans; Lidocaine; Mass Spectrometry; Narcotics; Phenacetin	2016
Characterization of the methemoglobin forming metabolites of benzocaine and lidocaine. Xenobiotica; the fate of foreign compounds in biological systems, 2017, Volume: 47, Issue:5 Topics: Acetaminophen; Anesthetics, Local; Benzocaine; Humans; Lidocaine; Methemoglobin; Methemoglobinemia	2017
AC electrokinetic drug delivery in dentistry using an interdigitated electrode assembly powered by inductive coupling. Biomedical microdevices, 2016, Volume: 18, Issue:5 Topics: Acetaminophen; Benzocaine; Carbamide Peroxide; Carboxylic Acids; Dentistry; Drug Delivery Systems; Electricity; Electrodes; Kinetics; Lidocaine; Microspheres; Motion; Peroxides; Tetracycline; Urea	2016
Chitosan-collagen based film for controlled delivery of a combination of short life anesthetics. International journal of biological macromolecules, 2019, Nov-01, Volume: 140 Topics: Anesthetics, Local; Animals; Benzocaine; Cattle; Cell Death; Cell Proliferation; Cell Survival; Chitosan; Collagen; Delayed-Action Preparations; Diffusion; Drug Delivery Systems; Drug Liberation; Fibroblasts; Humans; Hydrogen-Ion Concentration; Kinetics; Lidocaine; Molecular Weight; Permeability; Steam; Surface Properties; Tetracaine	2019
Topical Cetacaine is probably more effective in preventing pain than benzocaine and an eutectic mixture of local anesthetic before palatal infiltration in children. Journal of the American Dental Association (1939), 2020, Volume: 151, Issue:10 Topics: Administration, Topical; Anesthetics, Local; Benzalkonium Compounds; Benzocaine; Cetrimonium Compounds; Child; Drug Combinations; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Pain; Tetracaine	2020
Reagentless Voltammetric Identification of Cocaine from Complex Powders. Analytical chemistry, 2022, 09-20, Volume: 94, Issue:37 Topics: Benzocaine; Caffeine; Carbon Fiber; Cocaine; Levamisole; Lidocaine; Powders; Procaine; Water	2022
Hemolysis and acquired methemoglobinemia associated with lidocaine and benzocaine topical application: a case report. Journal of medical case reports, 2023, Apr-20, Volume: 17, Issue:1 Topics: Adult; Anesthetics, Local; Benzocaine; Hemolysis; Humans; Lidocaine; Male; Methemoglobinemia; Methylene Blue	2023