benzocaine and dibucaine

benzocaine has been researched along with dibucaine in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199021 (58.33)18.7374
1990's5 (13.89)18.2507
2000's3 (8.33)29.6817
2010's7 (19.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Batts, TW; Brown, ML; Jones, PJ; Landry, V; Patel, MK; Wang, Y1
Gozalbes, R; Pineda-Lucena, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Brouillette, WJ; Brown, GB; Zha, C1
Koblin, DD; Lester, HA1
DeStefano, MJ; Rabinovitch, M1
Janecke, JB1
Lee, AG1
Arenz, F; Pfeifer, H1
de Meis, L; Pacheco, AG; Wolosker, H1
Williams, AR1
Enyeart, JJ; Hinkle, PM; Phillips, WJ1
Hansen, J; Kreilgård, B1
Ivanov, II; Semin, BK; Tshudinovskich, MN1
Fischer, T; Hansen, J; Kreilgård, B1
Abe, K; Mashimo, T; Yoshiya, I1
Beck, MH; Holden, A1
Amano, Y; Kakinuma, T; Kobayashi, K; Koike, S; Nikura, M; Sagiya, T; Saito, Y; Suda, M; Yamaguchi, N; Yarita, M1
Bohn, E; Kunze, H; Vogt, W1
Forester, J; Kutscher, AH; Miya, C; Ruiz, L; Zegarelli, EV1
Bianchi, CP; Krupp, P; Suarez-Kurtz, G1
Ritchie, BR; Ritchie, JM1
Bell, FP1
Stadler, JK; Vaughan, VL1
Jain, MK; Singer, MA1
Bircher, AJ; Messmer, SL; Rufli, T; Surber, C1
Amano, K1
Mutlu, Z; Tulga, F1
Bauer, A; Elsner, P; Geier, J1
ADRIANI, J; ZEPERNICK, R1
Brinkmeier, T; Frosch, PJ; Kügler, K; Uter, W1
Baird, JA; Rinaldi, C; Santiago-Quinonez, D; Taylor, LS1
Brinca, A; Cabral, R; Gonçalo, M1
Deepika, A; Rao, CR; Rao, VV; Uloopi, KS; Vinay, C1
Schmutz, JL1

Trials

3 trial(s) available for benzocaine and dibucaine

ArticleYear
The local anaesthetic effects of cepacaine in post-tonsillectomy cases, pharyngitis and minor infections of the mouth.
    Current therapeutic research, clinical and experimental, 1976, Volume: 20, Issue:1

    Topics: Adult; Anesthetics, Local; Benzocaine; Cetylpyridinium; Clinical Trials as Topic; Dibucaine; Drug Combinations; Female; Humans; Male; Pain, Postoperative; Pharyngitis; Pyridinium Compounds; Stomatitis, Aphthous; Tonsillectomy; Ulcer

1976
[Clinical evaluation of new toothache drug "LTA"].
    Josai Shika Daigaku kiyo. The Bulletin of the Josai Dental University, 1986, Volume: 15, Issue:3

    Topics: Adult; Anesthetics, Local; Benzocaine; Child; Clinical Trials as Topic; Dibucaine; Ethanolamines; Eugenol; Female; Humans; Male; Middle Aged; Toothache

1986
Effectiveness of two flavored topical anesthetic agents in reducing injection pain in children: a comparative study.
    The Journal of clinical pediatric dentistry, 2012,Fall, Volume: 37, Issue:1

    Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Benzocaine; Child; Dibucaine; Female; Flavoring Agents; Humans; Injections; Lidocaine; Male; Mandibular Nerve; Needles; Nerve Block; Pain; Pain Measurement; Palate; Tooth Extraction; Tooth Mobility; Tooth, Deciduous; Treatment Outcome

2012

Other Studies

33 other study(ies) available for benzocaine and dibucaine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Ligand-based design and synthesis of novel sodium channel blockers from a combined phenytoin-lidocaine pharmacophore.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Drug Design; Expert Systems; Inhibitory Concentration 50; Lidocaine; Ligands; Models, Molecular; Phenytoin; Sodium Channel Blockers; Structure-Activity Relationship

2009
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
    Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1

    Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels

2014
Voltage-dependent and voltage-independent blockade of acetylcholine receptors by local anesthetics in Electrophorus electroplaques.
    Molecular pharmacology, 1979, Volume: 15, Issue:3

    Topics: Acetylcholine; Anesthetics, Local; Animals; Benzocaine; Chlorpromazine; Dibucaine; Electric Conductivity; Electric Organ; Electrophorus; In Vitro Techniques; Kinetics; Lidocaine; Membrane Potentials; Procaine; Receptors, Cholinergic; Receptors, Nicotinic; Tetracaine

1979
Cell shape changes induced by cationic anesthetics.
    The Journal of experimental medicine, 1976, Feb-01, Volume: 143, Issue:2

    Topics: Anesthetics, Local; Animals; Benzocaine; Cell Adhesion; Cell Fusion; Cell Membrane; Cell Movement; Chlorpromazine; Culture Media; Dibucaine; Edetic Acid; Egtazic Acid; Female; HEPES; Lidocaine; Macrophages; Mice; Prilocaine; Pseudopodia; Structure-Activity Relationship; Tetracaine; Tetrodotoxin; Tromethamine

1976
Interactions between anaesthetics and lipid mixtures. Amines.
    Biochimica et biophysica acta, 1976, Sep-21, Volume: 448, Issue:1

    Topics: Anesthetics, Local; Benzocaine; Binding Sites; Calcium; Chlorophyll; Dibucaine; Lipids; Membranes, Artificial; Myristic Acids; Neural Conduction; Palmitic Acids; Procaine; Sodium; Temperature; Tetracaine

1976
[Clinical study on the anesthesizing effect of the dentifrice Cepacain].
    ZWR, 1976, May-25, Volume: 85, Issue:10

    Topics: Anesthetics, Local; Benzocaine; Cetylpyridinium; Dentifrices; Dibucaine; Humans; Pyridinium Compounds

1976
Local anesthetics induce fast Ca2+ efflux through a nonenergized state of the sarcoplasmic reticulum Ca(2+)-ATPase.
    The Journal of biological chemistry, 1992, Mar-25, Volume: 267, Issue:9

    Topics: Anesthetics, Local; Animals; Benzocaine; Calcium; Calcium-Transporting ATPases; Dibucaine; Dose-Response Relationship, Drug; Heparin; Kinetics; Muscles; Polyamines; Proadifen; Procaine; Rabbits; Ruthenium Red; Sarcoplasmic Reticulum; Tetracaine

1992
Phonophoresis: an in vivo evaluation using three topical anaesthetic preparations.
    Ultrasonics, 1990, Volume: 28, Issue:3

    Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Benzocaine; Dibucaine; Drug Combinations; Electric Conductivity; Electric Stimulation; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Nociceptors; Phonophoresis; Prilocaine; Sensory Thresholds; Skin

1990
Pituitary thyrotropin-releasing hormone receptors: local anesthetic effects on binding and responses.
    Molecular endocrinology (Baltimore, Md.), 1989, Volume: 3, Issue:9

    Topics: Anesthetics, Local; Animals; Benzocaine; Chlordiazepoxide; Chlorpromazine; Dibucaine; Hydrogen-Ion Concentration; Imipramine; Lidocaine; Pituitary Gland; Procaine; Prolactin; Propranolol; Rats; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Tetracaine; Thyrotropin-Releasing Hormone; Trifluoperazine; Verapamil

1989
Aspects of pharmaceutical and chemical standardization of patch test materials.
    Journal of the American Academy of Dermatology, 1989, Volume: 21, Issue:4 Pt 2

    Topics: Acrolein; Acyclic Monoterpenes; Allergens; Benzocaine; Cellulose; Dermatitis, Contact; Dibucaine; Eugenol; Humans; Patch Tests; Pharmaceutical Vehicles; Povidone; Propanols; Quality Control; Skin Tests; Terpenes; Tetracaine; Thiazoles

1989
Local anesthetics-induced inhibition of chloroplast electron transport.
    General physiology and biophysics, 1989, Volume: 8, Issue:3

    Topics: Anesthetics, Local; Benzocaine; Chlorophyll; Chloroplasts; Dibucaine; Electron Transport; Hydrogen-Ion Concentration; Light; Light-Harvesting Protein Complexes; Mitochondria; Osmolar Concentration; Photosynthesis; Photosynthetic Reaction Center Complex Proteins; Plant Proteins; Tetracaine; Trimecaine

1989
Chemical, pharmaceutical and clinical standardization of the TRUE Test caine mix.
    Contact dermatitis, 1989, Volume: 21, Issue:1

    Topics: Adult; Aged; Benzocaine; Cellulose; Chromatography, High Pressure Liquid; Dibucaine; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Patch Tests; Pharmaceutical Vehicles; Povidone; Reference Standards; Skin Tests; Tetracaine

1989
Dual effect of local anesthetics on the function of excitable rod outer segment disk membrane.
    Anesthesiology, 1986, Volume: 64, Issue:4

    Topics: Anesthetics, Local; Animals; Benzocaine; Bupivacaine; Calcium; Cattle; Dibucaine; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; In Vitro Techniques; Lidocaine; Light; Photoreceptor Cells; Protons; Rhodopsin; Rod Cell Outer Segment; Tetracaine

1986
Benzocaine--an unsatisfactory indicator of topical local anaesthetic sensitization for the U.K.
    The British journal of dermatology, 1988, Volume: 118, Issue:1

    Topics: Benzocaine; Dibucaine; Drug Hypersensitivity; Humans; Patch Tests; Retrospective Studies; Tetracaine

1988
Effects of local anaesthetics on prostaglandin biosynthesis in vitro.
    Biochimica et biophysica acta, 1974, Sep-19, Volume: 360, Issue:3

    Topics: 4-Aminobenzoic Acid; Anesthetics, Local; Animals; Benzocaine; Calcium; Carbon Radioisotopes; Cattle; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Dibucaine; Edetic Acid; Kinetics; Lidocaine; Linoleic Acids; Male; Mepivacaine; Oleic Acids; Phosphatidylethanolamines; Phospholipases; Procaine; Prostaglandins; Seminal Vesicles; Sheep; Snakes; Species Specificity; Tetracaine; Triglycerides

1974
Long-lasting lozenges CU 701-1: dissolution duration time at home in patients with oral mucosal lesions.
    The Quarterly of the National Dental Association, Inc, 1969, Volume: 27, Issue:3

    Topics: Benzocaine; Delayed-Action Preparations; Dibucaine; Mouth Diseases; Solubility; Tablets; Triamcinolone Acetonide

1969
Effect of local anesthetics on radiocalcium binding in nerve.
    European journal of pharmacology, 1970, Volume: 10, Issue:1

    Topics: Achilles Tendon; Anesthetics, Local; Animals; Anura; Benzocaine; Binding Sites; Calcium; Calcium Isotopes; Dibucaine; Sciatic Nerve

1970
Local anesthetics: effect of pH on activity.
    Science (New York, N.Y.), 1968, Dec-20, Volume: 162, Issue:3860

    Topics: Action Potentials; Animals; Benzocaine; Chemical Phenomena; Chemistry, Physical; Depression, Chemical; Dibucaine; Hydrogen-Ion Concentration; In Vitro Techniques; Lidocaine; Neural Conduction; Neurons; Rabbits; Vagus Nerve

1968
Cholesterol esterification by rat adrenal gland. Inhibition by local anesthetics in vitro.
    Biochimica et biophysica acta, 1981, Oct-23, Volume: 666, Issue:1

    Topics: Acyl Coenzyme A; Acyltransferases; Adrenal Glands; Anesthetics, Local; Animals; Benzocaine; Cholesterol Esters; Dibucaine; Lidocaine; Male; Oleic Acids; Rats; Sterol O-Acyltransferase; Tetracaine

1981
Isolation and genetic characterization of dibucaine-resistant variants of a mouse lymphocytic cell line.
    Experimental cell research, 1980, Volume: 130, Issue:1

    Topics: Animals; Benzocaine; Cell Division; Cell Line; Dibucaine; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Hybrid Cells; Leukemia L5178; Lymphocytes; Mice; Mutation; Procaine; Tetracaine

1980
Interaction of four local anesthetics with phospholipid bilayer membranes: permeability effects and possible mechanisms.
    Canadian journal of biochemistry, 1980, Volume: 58, Issue:10

    Topics: Anesthetics, Local; Benzocaine; Chemical Phenomena; Chemistry; Dibucaine; Kinetics; Lipid Bilayers; Phosphatidylcholines; Procaine; Sodium; Structure-Activity Relationship; Temperature; Tetracaine

1980
Delayed-type hypersensitivity to subcutaneous lidocaine with tolerance to articaine: confirmation by in vivo and in vitro tests.
    Contact dermatitis, 1996, Volume: 34, Issue:6

    Topics: Adult; Anesthetics, Local; Benzocaine; Bupivacaine; Carticaine; Cross Reactions; Dermatitis, Allergic Contact; Dibucaine; Drug Eruptions; Drug Tolerance; Eczema; Edema; Female; Humans; Hypersensitivity, Delayed; Injections, Subcutaneous; Lidocaine; Lymphocyte Activation; Mepivacaine; Parabens; Patch Tests; Preservatives, Pharmaceutical; Prilocaine; Procaine; Quinolines; Recurrence; Skin Tests; Sulfites; Tetracaine

1996
[Clinical study of patients with positive reactions in patch tests with local anesthetics].
    Nihon Ika Daigaku zasshi, 1997, Volume: 64, Issue:2

    Topics: Anesthetics, Local; Benzocaine; Cross Reactions; Dermatitis, Allergic Contact; Dibucaine; Humans; Lidocaine; Patch Tests; Procaine

1997
Four types of topical anaesthetic agents: evaluation of clinical effectiveness.
    The Journal of clinical pediatric dentistry, 1999,Spring, Volume: 23, Issue:3

    Topics: Administration, Topical; Adolescent; Anesthesia, Dental; Anesthetics, Local; Benzocaine; Child; Dibucaine; Evaluation Studies as Topic; Facial Pain; Female; Gels; Humans; Injections; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Pain Measurement; Prilocaine; Tetracaine

1999
Allergic contact dermatitis in patients with anogenital complaints.
    The Journal of reproductive medicine, 2000, Volume: 45, Issue:8

    Topics: Adult; Anesthetics, Local; Anus Diseases; Benzocaine; Dermatitis, Allergic Contact; Dibucaine; Female; Genital Diseases, Female; Humans; Male; Ointment Bases; Patch Tests; Preservatives, Pharmaceutical; Thiazoles

2000
CLINICAL EFFECTIVENESS OF DRUGS USED FOR TOPICAL ANESTHESIA.
    JAMA, 1964, May-25, Volume: 188

    Topics: Anesthesia, Local; Anesthetics; Anesthetics, Local; Benzocaine; Cocaine; Dibucaine; Electric Stimulation; Humans; Lidocaine; Lip; Mepivacaine; Mucous Membrane; Palate; Pharmacology; Procaine; Sympathomimetics; Tetracaine; Tongue; Treatment Outcome; Tripelennamine

1964
[Anogenital dermatoses--allergic and irritative causative factors. Analysis of IVDK data and review of the literature].
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2005, Volume: 3, Issue:12

    Topics: Adult; Anesthetics, Local; Anus Diseases; Benzocaine; Bufexamac; Causality; Clinical Trials as Topic; Comorbidity; Databases, Factual; Dermatitis, Allergic Contact; Dermatology; Dibucaine; Female; Genital Diseases, Female; Genital Diseases, Male; Germany; Humans; Male; Middle Aged; Patch Tests; Prevalence; Risk Assessment; Risk Factors; Skin Diseases

2005
Role of viscosity in influencing the glass-forming ability of organic molecules from the undercooled melt state.
    Pharmaceutical research, 2012, Volume: 29, Issue:1

    Topics: Benzocaine; Calorimetry, Differential Scanning; Crystallization; Dibucaine; Lidocaine; Miconazole; Organic Chemicals; Procaine; Rheology; Thermodynamics; Tolbutamide; Transition Temperature; Viscosity

2012
Contact allergy to local anaesthetics-value of patch testing with a caine mix in the baseline series.
    Contact dermatitis, 2013, Volume: 68, Issue:3

    Topics: Adult; Anesthetics, Local; Benzocaine; Cross Reactions; Dermatitis, Allergic Contact; Dibucaine; Female; Humans; Male; Middle Aged; Patch Tests; Tetracaine; Young Adult

2013
[Generalised contact eczema: Care is needed in selecting a lubricant for digital rectal examination].
    Annales de dermatologie et de venereologie, 2015, Volume: 142, Issue:10

    Topics: Aged, 80 and over; Anesthetics, Local; Benzocaine; Conjunctivitis; Dermatitis, Allergic Contact; Dibucaine; Digital Rectal Examination; Eczema; Humans; Lubricants; Male; Ophthalmic Solutions; Patch Tests; Recurrence; Tetracaine

2015