benzocaine and butamben

benzocaine has been researched along with butamben in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199011 (21.15)18.7374
1990's15 (28.85)18.2507
2000's14 (26.92)29.6817
2010's9 (17.31)24.3611
2020's3 (5.77)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Arita, T; Juni, K; Nakano, M1
Ackerman, EW; Bal, F; Boon, WF; Crommelin, MA; Grouls, RJ; Hoefsloot, F; Korsten, HH; Ribot, JG; Slooff, JL; van Zundert, AA1
Bruynzeel, DP; van Ketel, WG1
Faulder, GC; Mazumdar, B; Tomlinson, AA1
Ackerman, EW; Grouls, RJ; Korsten, HH; Machielsen, EJ1
Ackerman, EW; Grouls, RJ; Gruys, E; Hellebrekers, LJ; Korsten, HH; van Herpen, H; van Zundert, AA1
Glickman, R; Greenfield, W; Hittelman, EL1
Amano, Y; Kakinuma, T; Kobayashi, K; Koike, S; Nikura, M; Sagiya, T; Saito, Y; Suda, M; Yamaguchi, N; Yarita, M1
Lue, RY; Zatz, JL1
Adriani, J; Beuttler, WA; Brihmadesam, L; Naraghi, M1
McEvoy, GK; Olson, ML1
Flynn, GL; Lalor, CB; Weiner, N1
Grouls, RJ; Korsten, HH; Van den Berg, RJ; Van Soest, PF; Wang, Z1
Armstrong, DG; Kanat, IO1
Kragh-Hansen, U; Maruyama, T; Otagiri, M; Yamasaki, K1
Ackerman, EW; Breimer, DD; Grouls, RJ; Hellebrekers, LJ; Korsten, HH; Machielsen, E1
Grouls, RJ; Korsten, HH; Van den Berg, RJ; Wang, Z1
Breimer, DD; Grouls, RJ; Hellebrekers, LJ; Korsten, HH; Meert, TF1
Ackerman, EW; Breimer, DD; Grouls, RJ; Hellebrekers, LJ; Korsten, HH1
Bommireddi, A; Ginsburg, E; Li, LC; Robinson, D; Stephens, D1
Cousins, MJ; Mitchell, VA; White, DM1
Bommireddi, AR; Buko, AM; Ginsburg, EJ; Li, LC; Robinson, DH; Stephens, DA; West, PR1
Fujiwara, Y; Kuroda, Y; Nakagawa, T; Nasu, H1
Ackerman, E; Breimer, D; Grouls, R; Hellebrekers, L; Korsten, E; van Zundert, A1
Harris, JE; Ivankovich, AD; Lubenow, TR; Nath, HA; Shulman, M1
Ivankovich, AD; Kerns, JM; McCarthy, RJ; Nath, HA; Shulman, M1
Blumberg, B; Cao, J; Grün, F; Hemmati, D; Tabb, MM; Venkatesan, RN; Zhou, C1
Beekwilder, JP; O'Leary, ME; van den Berg, RJ; van den Broek, LP; van Kempen, GT; Ypey, DL1
BAUMANN, J; PICARD-LEROY, G1
Cristea, M; Kolesnikov, YA; Pasternak, GW1
RONCHESE, F1
Beekwilder, JP; van den Berg, RJ; van Kempen, GTH; Winkelman, DLB; Ypey, DL1
Beck, CL; O'Leary, ME; Winkelman, DL; Ypey, DL1
Schmidt, AC1
Beekwilder, JP; van den Berg, RJ; van Kempen, GT; Ypey, DL1
Beekwilder, JP; Rampaart, LJ; van den Berg, RJ; van Kempen, GT; Ypey, DL1
LADEN, EL; RUBIN, L2
Ghelardini, C; González-Rodríguez, ML; Maestrelli, F; Mura, P; Rabasco, AM1
Han, YM; Kim, HJ; Kim, SH; Kwon, BM; Park, M1
Bang, S; Heo, TH; Hwang, SW; Yang, TJ; Yoo, S1
Casadei, BR; Cereda, CM; da Silva, CM; de Araujo, DR; de Paula, E; Domingues, CC; Franz-Montan, M; Tofoli, GR1
Chahine, M; de Groat, WC; O'Leary, ME; Poulin, H; Sculptoreanu, A; Thériault, O1
Berka, K; DeVane, RH; Murch, BP; Otyepka, M; Paloncýová, M1
Alkschbirs, MI; Cereda, CM; de Araujo, DR; de Brito Junior, RB; de Paula, E; Franz-Montan, M; Guilherme, VA; Tofoli, GR1
Krishna, GR; Rasmuson, ÅC; Svärd, M; Valavi, M; Zeng, L1
Breitkreitz, MC; Carvalho Dos Santos, A; Carvalho, NS; de Moura, LD; de Paula, E; Freitas de Lima, F; Geronimo, G; Lemes, JBP; Malange, KF; Parada, CA; Rodrigues da Silva, GH1
Beaudry, P; Bizat, N; Brandel, JP; Gougerot, A; Haïk, S; Laoues, S; Laplanche, JL; Levavasseur, E; Normant, S; Parrales, V; Privat, N; Ravassard, P; Roussel, J1
Breitkreitz, MC; de Paula, E; Mitsutake, H; Rodrigues da Silva, GH1

Trials

3 trial(s) available for benzocaine and butamben

ArticleYear
[Clinical evaluation of new toothache drug "LTA"].
    Josai Shika Daigaku kiyo. The Bulletin of the Josai Dental University, 1986, Volume: 15, Issue:3

    Topics: Adult; Anesthetics, Local; Benzocaine; Child; Clinical Trials as Topic; Dibucaine; Ethanolamines; Eugenol; Female; Humans; Male; Middle Aged; Toothache

1986
Analgesic efficacy of topical butamben picrate.
    Journal of the American Podiatric Medical Association, 1995, Volume: 85, Issue:12

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Benzocaine; Child; Female; Humans; Male; Middle Aged; Pain, Postoperative

1995
Comparison of epidural butamben to celiac plexus neurolytic block for the treatment of the pain of pancreatic cancer.
    The Clinical journal of pain, 2000, Volume: 16, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthetics, Local; Benzocaine; Celiac Plexus; Female; Humans; Male; Middle Aged; Nerve Block; Pain; Pancreatic Neoplasms; Treatment Outcome

2000

Other Studies

49 other study(ies) available for benzocaine and butamben

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship

2009
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Controlled drug permeation. II. Comparative permeability and stability of butamben and benzocaine.
    Chemical & pharmaceutical bulletin, 1977, Volume: 25, Issue:5

    Topics: Benzocaine; Drug Stability; Membranes, Artificial; Permeability

1977
Long-lasting epidural sensory blockade by n-butyl-p-aminobenzoate in the terminally ill intractable cancer pain patient.
    Anesthesiology, 1991, Volume: 75, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Benzocaine; Female; Humans; Male; Middle Aged; Neoplasms; Nerve Block; Pain, Intractable; Spinal Cord; Spinal Nerve Roots

1991
A 'forgotten' topical anaesthetic sensitizer: butyl aminobenzoate.
    Contact dermatitis, 1991, Volume: 25, Issue:2

    Topics: Anesthetics, Local; Benzocaine; Drug Eruptions; Eczema; Female; Humans; Male; Middle Aged

1991
Preliminary study to assay plasma amethocaine concentrations after topical application of a new local anaesthetic cream containing amethocaine.
    British journal of anaesthesia, 1991, Volume: 67, Issue:4

    Topics: Administration, Cutaneous; Adult; Anesthesia, Local; Anesthetics, Local; Benzocaine; Chromatography, High Pressure Liquid; Humans; Skin Absorption; Tetracaine; Time Factors

1991
Butyl-p-aminobenzoate. Preparation, characterization and quality control of a suspension injection for epidural analgesia.
    Pharmaceutisch weekblad. Scientific edition, 1991, Feb-22, Volume: 13, Issue:1

    Topics: Analgesics; Benzocaine; Drug Stability; Hydrogen-Ion Concentration; Injections, Epidural; Particle Size; Polyethylene Glycols; Polysorbates; Quality Control; Suspensions

1991
Long-lasting epidural sensory blockade by n-butyl p-aminobenzoate in the dog: neurotoxic or local anesthetic effect?
    Anesthesiology, 1990, Volume: 73, Issue:3

    Topics: Analgesia, Epidural; Anesthetics, Local; Animals; Benzocaine; Dogs; Female; Injections, Epidural; Male; Nervous System; Sensation; Time Factors

1990
Evaluation of anesthetic agents on human mucous membrane: an illustration of experimental protocol using computers.
    The New York state dental journal, 1986, Volume: 52, Issue:8

    Topics: Adult; Anesthetics, Local; Benzocaine; Computers; Female; Humans; Male; Mouth Mucosa; Random Allocation; Tetracaine; Time Factors

1986
Flocculation of suspensions containing nonionic surfactants by sorbitol.
    Journal of pharmaceutical sciences, 1987, Volume: 76, Issue:2

    Topics: Benzocaine; Flocculation; Polysorbates; Salicylamides; Sorbitol; Sulfamerazine; Surface-Active Agents; Suspensions; Temperature

1987
Topical anesthetics: use and misuse.
    Southern medical journal, 1985, Volume: 78, Issue:10

    Topics: Aerosols; Anesthetics, Local; Benzocaine; Humans; Lidocaine; Mouthwashes; Ointments; Powders; Propiophenones; Propoxycaine; Suppositories; Tablets; Tetracaine; Tripelennamine

1985
Methemoglobinemia induced by local anesthetics.
    American journal of hospital pharmacy, 1981, Volume: 38, Issue:1

    Topics: 4-Aminobenzoic Acid; Adult; Aminobenzoates; Anesthetics, Local; Benzocaine; Cyanosis; Humans; Intubation, Intratracheal; Male; Methemoglobinemia; Tetracaine

1981
Formulation factors affecting release of drug from topical vehicles. II. Effect of solubility on in vitro delivery of a series of n-alkyl p-aminobenzoates.
    Journal of pharmaceutical sciences, 1995, Volume: 84, Issue:6

    Topics: 4-Aminobenzoic Acid; Administration, Topical; Benzocaine; Chemical Phenomena; Chemistry, Physical; Diffusion; Drug Compounding; Drug Delivery Systems; Emulsions; Micelles; para-Aminobenzoates; Pharmaceutical Vehicles; Solubility; Spectrophotometry, Ultraviolet; Thermodynamics

1995
The local anesthetic n-butyl-p-aminobenzoate selectively affects inactivation of fast sodium currents in cultured rat sensory neurons.
    Anesthesiology, 1995, Volume: 82, Issue:6

    Topics: Action Potentials; Anesthetics, Local; Animals; Benzocaine; Cells, Cultured; Ganglia, Spinal; Rats; Sodium Channels; Tetrodotoxin

1995
Characterization of site I on human serum albumin: concept about the structure of a drug binding site.
    Biochimica et biophysica acta, 1996, Jul-18, Volume: 1295, Issue:2

    Topics: Acenocoumarol; Anticoagulants; Asparagine; Benzocaine; Binding Sites; Binding, Competitive; Dansyl Compounds; Fluorescent Dyes; Humans; Iodipamide; Phenylbutazone; Serum Albumin; Warfarin

1996
Capillary gas chromatographic method for the determination of n-butyl-p-aminobenzoate and lidocaine in plasma samples.
    Journal of chromatography. B, Biomedical applications, 1995, Nov-03, Volume: 673, Issue:1

    Topics: Anesthetics, Local; Animals; Benzocaine; Blood Specimen Collection; Calibration; Cholinesterase Inhibitors; Chromatography, Gas; Dogs; Drug Stability; Humans; Injections, Epidural; Isoflurophate; Lidocaine; Reproducibility of Results; Sensitivity and Specificity

1995
The local anesthetic, n-butyl-p-aminobenzoate, reduces rat sensory neuron excitability by differential actions on fast and slow Na+ current components.
    European journal of pharmacology, 1996, Nov-28, Volume: 316, Issue:1

    Topics: Action Potentials; Anesthetics, Local; Animals; Benzocaine; Ganglia, Spinal; Membrane Potentials; Neurons, Afferent; Rats; Sensitivity and Specificity; Sodium; Sodium Channels; Solutions; Tetrodotoxin

1996
Epidural and intrathecal n-butyl-p-aminobenzoate solution in the rat. Comparison with bupivacaine.
    Anesthesiology, 1997, Volume: 86, Issue:1

    Topics: Anesthesia, Epidural; Anesthetics, Local; Animals; Benzocaine; Bupivacaine; Dose-Response Relationship, Drug; Injections, Spinal; Rats; Rats, Wistar; Solutions

1997
Partition coefficients (n-octanol/water) of N-butyl-p-aminobenzoate and other local anesthetics measured by reversed-phase high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Jul-04, Volume: 694, Issue:2

    Topics: 1-Octanol; Anesthetics, Local; Benzocaine; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Octanols; Solubility; Water

1997
Particle size determination of a flocculated suspension using a light-scattering particle size analyzer.
    Drug development and industrial pharmacy, 1998, Volume: 24, Issue:11

    Topics: Benzocaine; Chemistry, Pharmaceutical; Flocculation; Humans; Light; Microscopy, Polarization; Particle Size; Scattering, Radiation; Suspensions

1998
The long-term effect of epidural administration of butamben suspension on nerve injury-induced allodynia in rats.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:4

    Topics: Analgesia, Epidural; Anesthetics, Local; Animals; Benzocaine; Disease Models, Animal; Locomotion; Longitudinal Studies; Male; Motor Activity; Neuralgia; Nociceptors; Pain Threshold; Pharmaceutical Vehicles; Physical Stimulation; Rats; Rats, Wistar; Sciatic Nerve; Time Factors

1999
Identification of a yellow impurity in aged samples of aqueous butamben suspension: evidence for the oxidative degradation of poly(ethylene glycol).
    Journal of pharmaceutical sciences, 2000, Volume: 89, Issue:6

    Topics: Benzocaine; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Polyethylene Glycols; Spectrometry, Mass, Fast Atom Bombardment; Water

2000
Orientations and locations of local anesthetics benzocaine and butamben in phospholipid membranes as studied by 2H NMR spectroscopy.
    The Journal of membrane biology, 2000, Sep-15, Volume: 177, Issue:2

    Topics: Anesthetics, Local; Benzocaine; Cholesterol; Deuterium; Magnetic Resonance Spectroscopy; Membranes, Artificial; Models, Biological; Molecular Conformation; Palmitic Acid; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Structure-Activity Relationship

2000
Diffusion of n-butyl-p-aminobenzoate (BAB), lidocaine and bupivacaine through the human dura-arachnoid mater in vitro.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2000, Volume: 12, Issue:2

    Topics: Anesthetics, Local; Arachnoid; Benzocaine; Bupivacaine; Diffusion; Dura Mater; Humans; In Vitro Techniques; Kinetics; Lidocaine; Spinal Cord

2000
The antinociceptive and histologic effect of sciatic nerve blocks with 5% butamben suspension in rats.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:3

    Topics: Anesthetics, Local; Animals; Benzocaine; Male; Nerve Block; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Suspensions; Time Factors

2002
Benzoate X receptors alpha and beta are pharmacologically distinct and do not function as xenobiotic receptors.
    The Journal of biological chemistry, 2002, Nov-15, Volume: 277, Issue:46

    Topics: Animals; Benzoates; Benzocaine; Chlorpyrifos; COS Cells; DNA, Complementary; Dose-Response Relationship, Drug; Female; Intestinal Mucosa; Ligands; Liver; Male; Parabens; Protein Binding; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; RNA; Tissue Distribution; Transfection; Trifluralin; Two-Hybrid System Techniques; Xenobiotics; Xenopus; Xenopus Proteins

2002
Kv1.1 channels of dorsal root ganglion neurons are inhibited by n-butyl-p-aminobenzoate, a promising anesthetic for the treatment of chronic pain.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:2

    Topics: Action Potentials; Anesthetics, Local; Animals; Benzocaine; Cells, Cultured; Chronic Disease; Ganglia, Spinal; Humans; In Vitro Techniques; Kv1.1 Potassium Channel; Mice; Neurons; Pain; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated

2003
[Danger in the use of procaine with butyl aminobenzoate in thoracic surgery].
    Le Poumon, 1954, Volume: 10, Issue:2

    Topics: Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Benzocaine; Pain; Pain Management; Procaine; Thoracic Surgery; Thorax

1954
Analgesic synergy between topical morphine and butamben in mice.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:4

    Topics: Administration, Topical; Analgesics, Opioid; Anesthetics, Local; Animals; Benzocaine; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Lidocaine; Male; Mice; Mice, Inbred ICR; Morphine; Pain Measurement; Reaction Time

2003
Dermatitis venenata from butesin picrate ointment.
    Industrial medicine & surgery, 1951, Volume: 20, Issue:12

    Topics: Benzocaine; Burns; Dermatitis, Contact; Drug Eruptions; Picrates

1951
The block of total and N-type calcium conductance in mouse sensory neurons by the local anesthetic n-butyl-p-aminobenzoate.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:6

    Topics: Action Potentials; Algorithms; Anesthetics, Local; Animals; Animals, Newborn; Barium; Benzocaine; Calcium Channel Blockers; Calcium Channels, N-Type; Ganglia, Spinal; Membrane Potentials; Mice; Neurons, Afferent; Patch-Clamp Techniques

2005
Inhibition of the A-type K+ channels of dorsal root ganglion neurons by the long-duration anesthetic butamben.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Amino Acid Sequence; Anesthetics, Local; Animals; Benzocaine; Ganglia, Spinal; Ion Channel Gating; Molecular Sequence Data; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Rats; Shal Potassium Channels; Tetraethylammonium

2005
Structural characteristics and crystal polymorphism of three local anaesthetic bases crystal polymorphism of local anaesthetic drugs: part VII.
    International journal of pharmaceutics, 2005, Jul-14, Volume: 298, Issue:1

    Topics: Anesthetics, Local; Benzocaine; Calorimetry, Differential Scanning; Crystallization; Drug Stability; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thermodynamics; X-Ray Diffraction

2005
The local anesthetic butamben inhibits and accelerates low-voltage activated T-type currents in small sensory neurons.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:1

    Topics: Action Potentials; Anesthetics, Local; Animals; Animals, Newborn; Benzocaine; Calcium Channel Blockers; Calcium Channels, T-Type; Cells, Cultured; Dose-Response Relationship, Drug; Mice; Neurons, Afferent

2006
The local anesthetic butamben inhibits total and L-type barium currents in PC12 cells.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:6

    Topics: Analgesics; Anesthetics, Local; Animals; Barium; Benzocaine; Calcium Channel Blockers; Calcium Channels, L-Type; Neurons; Nifedipine; Patch-Clamp Techniques; PC12 Cells; Rats

2008
Epidermal sensitization to butesin, an experimental study on the range of specificity.
    The Journal of investigative dermatology, 1948, Volume: 11, Issue:2

    Topics: Anesthesia, Local; Benzocaine; Epidermis; Sensitivity and Specificity

1948
Specificity of eczematous hypersensitivity to p-aminobenzoic acid butyl ester (butesin).
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1947, Volume: 66, Issue:2

    Topics: 4-Aminobenzoic Acid; Acids; Benzocaine; Eczema; Esters; Hypersensitivity

1947
New "drug-in cyclodextrin-in deformable liposomes" formulations to improve the therapeutic efficacy of local anaesthetics.
    International journal of pharmaceutics, 2010, Aug-16, Volume: 395, Issue:1-2

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Amines; Anesthetics, Local; Animals; Benzocaine; beta-Cyclodextrins; Chemistry, Pharmaceutical; Cholesterol; Conjunctiva; Dialysis; Drug Carriers; Drug Compounding; Kinetics; Light; Liposomes; Male; Microscopy, Confocal; Particle Size; Permeability; Phosphatidylcholines; Rabbits; Reflex; Scattering, Radiation; Sensory Thresholds; Solubility; Surface Properties; Surface-Active Agents; Technology, Pharmaceutical

2010
Butamben derivatives enhance BMP-2-stimulated commitment of C2C12 cells into osteoblasts with induction of voltage-gated potassium channel expression.
    Bioorganic & medicinal chemistry letters, 2011, Dec-15, Volume: 21, Issue:24

    Topics: 4-Aminobenzoic Acid; Alkaline Phosphatase; Animals; Benzocaine; Bone Morphogenetic Protein 2; Cell Differentiation; Cell Line; Gene Expression Regulation; Mice; Osteoblasts; para-Aminobenzoates; Potassium Channels, Voltage-Gated; RNA, Messenger; Signal Transduction

2011
Inhibition of sensory neuronal TRPs contributes to anti-nociception by butamben.
    Neuroscience letters, 2012, Jan-11, Volume: 506, Issue:2

    Topics: Anesthetics, Local; Animals; Benzocaine; HEK293 Cells; Humans; Pain; Patch-Clamp Techniques; Sensory Receptor Cells; TRPC Cation Channels; TRPV Cation Channels

2012
Transdermal delivery of butamben using elastic and conventional liposomes.
    Journal of liposome research, 2013, Volume: 23, Issue:3

    Topics: Administration, Cutaneous; Anesthetics, Local; Animals; Benzocaine; Drug Compounding; Elasticity; Fluorescence Polarization; Gels; Liposomes; Particle Size; Reproducibility of Results; Skin Absorption; Swine

2013
Modulation of peripheral Na(+) channels and neuronal firing by n-butyl-p-aminobenzoate.
    European journal of pharmacology, 2014, Mar-15, Volume: 727

    Topics: Action Potentials; Anesthetics, Local; Animals; Benzocaine; Dose-Response Relationship, Drug; Ganglia, Spinal; HEK293 Cells; Humans; Male; NAV1.6 Voltage-Gated Sodium Channel; NAV1.7 Voltage-Gated Sodium Channel; NAV1.8 Voltage-Gated Sodium Channel; Neurons; Rats, Sprague-Dawley; Sodium Channel Blockers; Time Factors; Transfection; Voltage-Gated Sodium Channels

2014
Rationalization of reduced penetration of drugs through ceramide gel phase membrane.
    Langmuir : the ACS journal of surfaces and colloids, 2014, Nov-25, Volume: 30, Issue:46

    Topics: Anesthetics, Local; Benzocaine; Ceramides; Lipid Bilayers; Models, Chemical; Phosphatidylcholines

2014
Liposomal butamben gel formulations: toxicity assays and topical anesthesia in an animal model.
    Journal of liposome research, 2017, Volume: 27, Issue:1

    Topics: 3T3 Cells; Administration, Topical; Anesthesia, Local; Animals; Benzocaine; Cell Survival; Cells, Cultured; Disease Models, Animal; Gels; Injections, Intraperitoneal; Liposomes; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar

2017
Solid and Solution State Thermodynamics of Polymorphs of Butamben (Butyl 4-Aminobenzoate) in Pure Organic Solvents.
    Journal of pharmaceutical sciences, 2019, Volume: 108, Issue:7

    Topics: 2-Propanol; Benzocaine; Calorimetry, Differential Scanning; Crystallization; Hot Temperature; Methanol; Solubility; Solvents; Temperature; Thermodynamics; Transition Temperature; X-Ray Diffraction

2019
Lipid nanoparticles loaded with butamben and designed to improve anesthesia at inflamed tissues.
    Biomaterials science, 2021, May-04, Volume: 9, Issue:9

    Topics: Anesthesia; Animals; Benzocaine; Drug Carriers; Lipids; Nanoparticles; Nanostructures; Particle Size; Rats

2021
An in vivo Caenorhabditis elegans model for therapeutic research in human prion diseases.
    Brain : a journal of neurology, 2021, 10-22, Volume: 144, Issue:9

    Topics: Animals; Animals, Genetically Modified; Benzocaine; Brain; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Humans; Naloxone; Piroxicam; Prion Diseases; Prion Proteins; Protein Aggregation, Pathological; Tubulin

2021
When it is too much: Identifying butamben excess on the surface of pharmaceutical preformulation samples by Raman mapping.
    Journal of pharmaceutical and biomedical analysis, 2023, Oct-25, Volume: 235

    Topics: Benzocaine; Excipients; Lipids; Pharmaceutical Preparations

2023