Page last updated: 2024-09-03

benzo(g)chrysene-11,12-dihydrodiol-13,14-epoxide and dactinomycin

benzo(g)chrysene-11,12-dihydrodiol-13,14-epoxide has been researched along with dactinomycin in 3 studies

Compound Research Comparison

Studies
(benzo(g)chrysene-11,12-dihydrodiol-13,14-epoxide)
Trials
(benzo(g)chrysene-11,12-dihydrodiol-13,14-epoxide)
Recent Studies (post-2010)
(benzo(g)chrysene-11,12-dihydrodiol-13,14-epoxide)
Studies
(dactinomycin)
Trials
(dactinomycin)
Recent Studies (post-2010) (dactinomycin)
140019,045355969

Protein Interaction Comparison

ProteinTaxonomybenzo(g)chrysene-11,12-dihydrodiol-13,14-epoxide (IC50)dactinomycin (IC50)
RAD51Homo sapiens (human)32.1
Growth factor receptor-bound protein 2Homo sapiens (human)5
Discoidin domain-containing receptor 2Homo sapiens (human)9
Growth factor receptor-bound protein 2 Mus musculus (house mouse)5

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dipple, A; Khan, QA; Vousden, KH1
Anderson, LM; Khan, QA1
Anderson, LM; Dipple, A; Khan, QA1

Other Studies

3 other study(ies) available for benzo(g)chrysene-11,12-dihydrodiol-13,14-epoxide and dactinomycin

ArticleYear
Cellular response to DNA damage from a potent carcinogen involves stabilization of p53 without induction of p21(waf1/cip1).
    Carcinogenesis, 1997, Volume: 18, Issue:12

    Topics: Carcinogens; Cell Cycle; Chrysenes; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dactinomycin; DNA Damage; Female; Humans; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1997
Hydrocarbon carcinogens evade cellular defense mechanism of G1 arrest in nontransformed and malignant lung cell lines.
    Toxicology and applied pharmacology, 2001, Jun-01, Volume: 173, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Animals; Antineoplastic Agents; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chrysenes; Dactinomycin; DNA Damage; Epithelial Cells; Flow Cytometry; G1 Phase; Genes, p53; Humans; Lung; Lung Neoplasms; Mice; Mutagens; Mutation; Nocodazole; Nucleic Acid Synthesis Inhibitors; Tumor Cells, Cultured

2001
Protease inhibitor-induced stabilization of p21(waf1/cip1) and cell-cycle arrest in chemical carcinogen-exposed mammary and lung cells.
    Molecular carcinogenesis, 2002, Volume: 33, Issue:1

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Carcinogens; Cell Cycle; Chrysenes; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Dactinomycin; Epithelial Cells; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Lung; Mice; Nocodazole; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002