benzo(c)phenanthrene has been researched along with phenanthrenes in 44 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 13 (29.55) | 18.7374 |
1990's | 12 (27.27) | 18.2507 |
2000's | 18 (40.91) | 29.6817 |
2010's | 1 (2.27) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Jerina, DM; Kollman, PA; Lybrand, T; Michaud, D; Rao, SN | 1 |
Mushtaq, M; Yang, SK | 1 |
Balani, SK; Boyd, DR; Jerina, DM; Levin, W; Ryan, DE; Sayer, JM; Thakker, DR; Thomas, PE; van Bladeren, PJ | 1 |
Boehlert, C; Byrd, RA; Mirsadeghi, S; Prasad, GK; Thakker, DR | 1 |
Mushtaq, M; Weems, HB; Yang, SK | 1 |
Baird, WM; Dipple, A; Jerina, DM; Pigott, MA; Pruess-Schwartz, D; Yagi, H | 1 |
Grimmer, G; Hamann, M; Jacob, J; Raab, G; Schmoldt, A | 1 |
Chang, RL; Conney, AH; Croisy-Delcey, M; Ittah, Y; Jerina, DM; Levin, W; Ryan, DE; Thomas, PE; Wood, AW; Yagi, H | 1 |
Chang, RL; Conney, AH; Croisy-Delcey, M; Ittah, Y; Jerina, DM; Levin, W; Sayer, JM; Thakker, DR; Wood, AW; Yagi, H | 1 |
Silverman, BD | 1 |
Abu-Shqara, E; Blum, J; Glatt, H; Harvey, RG | 1 |
Lewis-Bevan, L; Little, SB; Rabinowitz, JR | 1 |
Giles, AS; Phillips, DH; Seidel, A | 1 |
Amin, S; Broyde, S; Cosman, M; Fiala, R; Geacintov, NE; Hingerty, BE; Laryea, A; Patel, DJ | 1 |
Funk, M; Gath, I; Oesch, F; Platt, KL; Seidel, A; Zeller, HD | 1 |
Amin, S; Desai, D; Hecht, SS | 1 |
Amin, S; Broyde, S; Cosman, M; Fiala, R; Geacintov, NE; Harvey, RG; Hingerty, BE; Laryea, A; Lee, H; Patel, D | 1 |
Amin, S; el-Bayoumy, K; Hecht, SS; Rivenson, A | 1 |
Osborne, MR; Seidel, A; Tinker, MH; Windsor, SA | 1 |
Amin, S; Baird, WM; Einolf, HJ; Jerina, DM; Yagi, H | 1 |
Amin, S; Baird, WM; Einolf, HJ; Gelboin, HV; Greenlee, WF; Jefcoate, CR; Jerina, DM; Larsen, MC; Marcus, CB; Park, SS; Story, WT; Yagi, H | 1 |
Möller, L; Zeisig, M | 1 |
Jerina, DM; Sayer, JM; Vepachedu, SR; Ya, N; Yagi, H | 1 |
Dipple, A; Jerina, DM; Pilcher, AS; Pontén, I; Sayer, JM; Waters, LS | 1 |
Amin, S; Geacintov, NE; Roth, RB; Scicchitano, DA | 1 |
Gu, Y; Ji, X; Pal, A; Pan, SS; Singh, SV | 1 |
Amin, S; Baum, M; Eisenbrand, G; Guengerich, FP; Hecht, SS; Köhl, W | 1 |
Galembeck, SE; Kumar, S; Laali, KK; Okazaki, T | 1 |
Broyde, S; Geacintov, NE; Patel, DJ; Wu, M; Yan, S | 1 |
Chang, RL; Conney, AH; Cui, XX; Jerina, DM; Schiltz, M; Wei, SJ; Yagi, H | 1 |
Blankenship, LR; Chang, HF; Chiarelli, MP; Cho, BP; Culp, SJ; Huffer, DM | 1 |
Brown, KW; Little, SB; Rabinowitz, JR | 1 |
HATEM, S | 2 |
Gu, L; Kindy, MS; Li, GM; Qiu, L; Seidel, A; Wu, J; Yu, J; Zhu, BB; Zhu, H | 1 |
Handy, CJ; Jerina, DM; Pirrung, M; Sayer, JM; Shuman, S; Yakovleva, L | 1 |
Broyde, S; Geacintov, NE; Patel, DJ; Tan, J; Wu, M; Yan, SF | 1 |
Broyde, S; Geacintov, NE; Patel, DJ; Wang, L; Wu, M; Yan, SF | 1 |
Brulé, C; Laali, KK; Lakshman, MK; Okazaki, T | 1 |
Jerina, DM; Kroth, H; Kumar, S; Sayer, JM; Schnetz-Boutaud, NC; Stone, MP; Wang, Y; Yagi, H | 1 |
Gupta, VP; Mishra, S; Pratap, R; Ram, VJ; Thul, P | 1 |
Demarini, DM; King, LC; Kumar, S; Nesnow, S; Sikka, H; Swartz, CD; Umbach, DM | 1 |
Chen, K; Hano, T; Hashiguchi, Y; Hayakawa, K; Honda, M; Nakayama, K; Oshima, Y; Qiu, X; Shimasaki, Y; Suzuki, N; Tashiro, K; Tsutsumi, Y; Xu, H; Yoshitake, S | 1 |
1 review(s) available for benzo(c)phenanthrene and phenanthrenes
Article | Year |
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Dose-dependent differences in the profile of mutations induced by carcinogenic (R,S,S,R) bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons.
Topics: Acridines; Amino Acid Substitution; Animals; Base Sequence; Bay-Region, Polycyclic Aromatic Hydrocarbon; Benzo(a)pyrene; Carcinogens; Dose-Response Relationship, Drug; Epoxy Compounds; Genes, ras; Humans; Hypoxanthine Phosphoribosyltransferase; Molecular Sequence Data; Mutagenesis; Phenanthrenes; Polycyclic Aromatic Hydrocarbons; Proto-Oncogene Mas; Skin Neoplasms | 2001 |
43 other study(ies) available for benzo(c)phenanthrene and phenanthrenes
Article | Year |
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Molecular mechanics simulations on covalent complexes between polycyclic carcinogens and B-DNA.
Topics: Benzo(a)pyrene; Benzopyrenes; Chemical Phenomena; Chemistry; DNA; DNA Damage; Epoxy Compounds; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Phenanthrenes; Structure-Activity Relationship; Thermodynamics | 1989 |
Stereoselective metabolism of benzo[c]phenanthrene to the procarcinogenic trans-3,4-dihydrodiol.
Topics: Animals; Carcinogens; Circular Dichroism; Cytochrome P-450 Enzyme System; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Mutagens; Phenanthrenes; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred Strains; Stereoisomerism | 1987 |
Stereoselective formation of benzo(c)phenanthrene (+)-(3S,4R) and (+)-(5S,6R)-oxides by cytochrome P450c in a highly purified and reconstituted system.
Topics: Animals; Cytochrome P-450 Enzyme System; Kinetics; Microsomes, Liver; Mutagens; NADPH-Ferrihemoprotein Reductase; Phenanthrenes; Rats; Stereoisomerism | 1987 |
Oxidative metabolism of the carcinogen 6-fluorobenzo[c]phenanthrene. Effect of a K-region fluoro substituent on the regioselectivity of cytochromes P-450 in liver microsomes from control and induced rats.
Topics: Animals; Binding Sites; Carcinogens; Cytochrome P-450 Enzyme System; Hydrocarbons, Fluorinated; Magnetic Resonance Spectroscopy; Male; Methylcholanthrene; Microsomes, Liver; Molecular Conformation; Oxidation-Reduction; Phenanthrenes; Phenobarbital; Protein Binding; Rats; Reference Values; Structure-Activity Relationship | 1988 |
Stereoselective formation and hydration of benzo[c]phenanthrene 3,4- and 5,6-epoxide enantiomers by rat liver microsomal enzymes.
Topics: Animals; Catalysis; Chromatography, High Pressure Liquid; Circular Dichroism; Epoxy Compounds; Male; Microsomes, Liver; Molecular Conformation; Phenanthrenes; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Stereoisomerism | 1987 |
Stereochemical specificity in the metabolic activation of benzo(c)phenanthrene to metabolites that covalently bind to DNA in rodent embryo cell cultures.
Topics: Animals; Biotransformation; Cells, Cultured; Cricetinae; DNA; DNA Damage; Mesocricetus; Mice; Phenanthrenes; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship | 1987 |
Benzo[c]phenanthrene.
Topics: Animals; Carcinogens, Environmental; Chemical Phenomena; Chemistry; Female; Mice; Mutagenicity Tests; Neoplasms, Experimental; Phenanthrenes; Rats; Risk; Skin Neoplasms | 1983 |
Induction of specific monooxygenases by isosteric heterocyclic compounds of benz[a]anthracene, benzo[c]phenanthrene and chrysene.
Topics: Animals; Benz(a)Anthracenes; Chrysenes; Enzyme Induction; Male; Microsomes, Liver; Mutagens; Phenanthrenes; Polycyclic Compounds; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1983 |
Mutagenicity of the dihydrodiols and bay-region diol-epoxides of benzo(c)phenanthrene in bacterial and mammalian cells.
Topics: Animals; Biotransformation; Cell Line; Cell Survival; Cells, Cultured; Cricetinae; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Microsomes, Liver; Mutagens; Phenanthrenes; Rats; Salmonella typhimurium; Structure-Activity Relationship | 1980 |
Highly tumorigenic bay-region diol epoxides from the weak carcinogen benzo[c]phenanthrene.
Topics: Animals; Biotransformation; Carcinogens; Chemical Phenomena; Chemistry; Epoxy Compounds; Ethers, Cyclic; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Phenanthrenes; Rats; Salmonella typhimurium; Structure-Activity Relationship | 1981 |
Steric crowding and conformer stability of the diol-epoxides of benzo(c)phenanthrene.
Topics: Epoxy Compounds; Models, Molecular; Molecular Conformation; Phenanthrenes; Structure-Activity Relationship | 1982 |
Mutagenicity of K-region oxides and imines of chrysene, benzo[c]phenanthrene and benzo[g]chrysene in Salmonella typhimurium.
Topics: Aziridines; Chrysenes; Dose-Response Relationship, Drug; Epoxy Compounds; Imines; Mutagenesis; Mutagenicity Tests; Mutagens; Phenanthrenes; Salmonella typhimurium | 1994 |
Quantum mechanical studies of the structure and reactivities of the diol epoxides of benzo[c]phenanthrene.
Topics: Chemical Phenomena; Chemistry, Physical; Epoxy Compounds; Molecular Conformation; Mutagens; Phenanthrenes; Quantum Theory; Structure-Activity Relationship | 1995 |
In vitro reaction with DNA of the fjord-region diol epoxides of benzo[g]chrysene and benzo[c]phenanthrene as studied by 32P-postlabeling.
Topics: Autoradiography; Base Sequence; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Chrysenes; DNA; DNA Adducts; Epoxy Compounds; Isomerism; Isotope Labeling; Molecular Sequence Data; Mutagens; Phenanthrenes; Phosphorus Radioisotopes; Single-Strand Specific DNA and RNA Endonucleases | 1995 |
Solution conformation of the (-)-trans-anti-benzo[c]phenanthrene-dA ([BPh]dA) adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrenyl ring to the 3'-side of the adduct site and comparison with the (+)-trans-anti-
Topics: Base Sequence; Carcinogens; DNA; Hydrogen Bonding; Intercalating Agents; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Phenanthrenes | 1995 |
Different enzyme kinetics during the glutathione conjugation of the four stereoisomers of the fjord-region diolepoxides of benzo[c]phenanthrene by the mu-class rat liver glutathione S-transferase HTP II.
Topics: Animals; Benz(a)Anthracenes; Glutathione; Glutathione Transferase; Inactivation, Metabolic; Kinetics; Liver; Phenanthrenes; Rats; Stereoisomerism | 1994 |
Tumor-initiating activity on mouse skin of bay region diol-epoxides of 5,6-dimethylchrysene and benzo[c]phenanthrene.
Topics: Animals; Biotransformation; Carcinogens; Chrysenes; Female; Mice; Phenanthrenes; Skin | 1993 |
Solution conformation of the (+)-trans-anti-[BPh]dA adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrene to the 5'-side of the adduct site without disruption of the modified base pair.
Topics: Base Sequence; Carcinogens; DNA; DNA Damage; Intercalating Agents; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutagens; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Phenanthrenes; Solutions; Stereoisomerism | 1993 |
Potent mammary carcinogenicity in female CD rats of a fjord region diol-epoxide of benzo[c]phenanthrene compared to a bay region diol-epoxide of benzo[a]pyrene.
Topics: Adenocarcinoma; Animals; Benzo(a)pyrene; Epoxy Compounds; Female; Fibroadenoma; Mammary Neoplasms, Experimental; Phenanthrenes; Rats; Rats, Inbred Strains | 1994 |
Studies of the binding of diolepoxide metabolites of polycyclic aromatic hydrocarbons to DNA using electrofluorescence polarization spectroscopy.
Topics: Bay-Region, Polycyclic Aromatic Hydrocarbon; Benzo(a)pyrene; DNA Adducts; Phenanthrenes; Polycyclic Aromatic Hydrocarbons; Spectrometry, Fluorescence; Stereoisomerism | 1996 |
Benzo[c]phenanthrene is activated to DNA-binding diol epoxides in the human mammary carcinoma cell line MCF-7 but only limited activation occurs in mouse skin.
Topics: Animals; Biotransformation; Breast Neoplasms; Carcinogenicity Tests; Carcinoma; DNA Adducts; DNA, Neoplasm; Epoxy Compounds; Female; Humans; Mice; Phenanthrenes; Skin; Species Specificity; Tumor Cells, Cultured | 1996 |
Role of cytochrome P450 enzyme induction in the metabolic activation of benzo[c]phenanthrene in human cell lines and mouse epidermis.
Topics: Animals; Biotransformation; Breast Neoplasms; Carcinogens; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; Enzyme Induction; Epidermal Cells; Epidermis; Female; Humans; Liver Neoplasms; Mice; Mice, Inbred SENCAR; Phenanthrenes; Tumor Cells, Cultured | 1997 |
32P-Postlabeling high-performance liquid chromatographic improvements to characterize DNA adduct stereoisomers from benzo[a]pyrene and benzo[c]phenanthrene, and to separate DNA adducts from 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cattle; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxyguanosine; DNA Adducts; Mutagens; Phenanthrenes; Phosphorus Radioisotopes; Reproducibility of Results; Stereoisomerism | 1997 |
Marked differences in base selectivity between DNA and the free nucleotides upon adduct formation from Bay- and Fjord-region diol epoxides.
Topics: Animals; Bay-Region, Polycyclic Aromatic Hydrocarbon; Benzo(a)pyrene; Cattle; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; DNA; DNA Adducts; Epoxy Compounds; Phenanthrenes | 2000 |
Influence of adduct position and sequence length on the ligation of oligonucleotides containing benzo[c]phenanthrene diol epoxide-deoxyadenosine adducts into M13mp7L2.
Topics: Bacteriophage M13; Base Sequence; Blotting, Southern; Circular Dichroism; Deoxyadenosines; DNA Adducts; DNA, Bacterial; DNA, Circular; Escherichia coli; Genetic Vectors; Mutagens; Nucleic Acid Hybridization; Oligonucleotides; Phenanthrenes | 2001 |
Bacteriophage T7 RNA polymerase transcription elongation is inhibited by site-specific, stereospecific benzo[c]phenanthrene diol epoxide DNA lesions.
Topics: Bacteriophage T7; Base Composition; DNA Adducts; DNA-Directed RNA Polymerases; DNA, Single-Stranded; Environmental Pollutants; Oligodeoxyribonucleotides; Peptide Chain Elongation, Translational; Phenanthrenes; RNA, Viral; Sequence Analysis, RNA; Stereoisomerism; Templates, Genetic; Transcription, Genetic; Viral Proteins | 2001 |
C-terminal region amino acid substitutions contribute to catalytic differences between murine class alpha glutathione transferases mGSTA1-1 and mGSTA2-2 toward anti-diol epoxide isomers of benzo[c]phenanthrene.
Topics: Amino Acid Substitution; Animals; Carcinogens; Catalysis; Enzyme Activation; Glutathione; Glutathione Transferase; Isoenzymes; Mice; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments; Phenanthrenes; Recombinant Fusion Proteins; Stereoisomerism; Structure-Activity Relationship | 2001 |
Metabolic activation of benzo[c]phenanthrene by cytochrome P450 enzymes in human liver and lung.
Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme System; Escherichia coli; Humans; Lung; Microsomes, Liver; Mutagens; Phenanthrenes; Rats; Risk Assessment; Salmonella typhimurium | 2001 |
Substituent effects and charge delocalization mode in chrysenium, benzo[c]phenanthrenium, and benzo[g]chrysenium cations: a stable ion and electrophilic substitution study.
Topics: Chrysenes; Magnetic Resonance Spectroscopy; Phenanthrenes; Thermodynamics | 2001 |
Cyclohexene ring and Fjord region twist inversion in stereoisomeric DNA adducts of enantiomeric benzo[c]phenanthrene diol epoxides.
Topics: Cyclohexanes; Cyclohexenes; DNA; DNA Adducts; Epoxy Compounds; Models, Molecular; Molecular Conformation; Mutagens; Phenanthrenes; Stereoisomerism; Structure-Activity Relationship | 2001 |
Characterization of DNA adducts derived from syn-benzo[ghi]fluoranthene-3,4-dihydrodiol-5,5a-epoxide and comparative DNA binding studies with structurally-related anti-diolepoxides of benzo[ghi]fluoranthene and benzo[c]phenanthrene.
Topics: Animals; Binding Sites; Cattle; Chromatography, High Pressure Liquid; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Fluorenes; Isomerism; Molecular Conformation; Mutagenicity Tests; Mutagens; Phenanthrenes; Salmonella typhimurium | 2002 |
Benzo[a]pyrene and benz[c]phenanthrene: the effect of structure on the binding of water molecules to the diol epoxides.
Topics: Benzo(a)pyrene; Binding Sites; Computer Simulation; Epoxy Compounds; Molecular Conformation; Phenanthrenes; Structure-Activity Relationship; Water | 2002 |
[The affinity of histamine for carcinogenic stilbenes and for 3,4-benzophenanthrene; observation in vitro and verification in vivo].
Topics: Carcinogens; Histamine; In Vitro Techniques; Phenanthrenes; Stilbenes | 1958 |
[Fixation of histamine & nerve destruction by stilbenic carcinogenic substances & by 3,4-benzophenanthrene].
Topics: Carcinogens; Histamine; Histological Techniques; Neurosurgical Procedures; Phenanthrenes; Stilbenes | 1958 |
In vitro and in vivo modulations of benzo[c]phenanthrene-DNA adducts by DNA mismatch repair system.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Animals; Apoptosis; Bacterial Proteins; Base Pair Mismatch; Carrier Proteins; Cell Line; Cell Line, Tumor; Cell Survival; DNA; DNA Adducts; DNA Repair; DNA-Binding Proteins; HeLa Cells; Humans; In Situ Nick-End Labeling; Intestine, Small; Mice; Mice, Knockout; Mutagens; Mutation; MutL Protein Homolog 1; MutS DNA Mismatch-Binding Protein; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Oligonucleotides; Phenanthrenes; Protein Binding; Proto-Oncogene Proteins | 2003 |
Benzo[c]phenanthrene adducts and nogalamycin inhibit DNA transesterification by vaccinia topoisomerase.
Topics: Base Pairing; Base Sequence; DNA Adducts; DNA Topoisomerases, Type I; Hydrolysis; Intercalating Agents; Models, Molecular; Molecular Sequence Data; Nogalamycin; Nucleic Acid Conformation; Phenanthrenes; Vaccinia virus | 2004 |
Conformational searches elucidate effects of stereochemistry on structures of deoxyadenosine covalently bound to tumorigenic metabolites of benzo[C] phenanthrene.
Topics: Carcinogens; Deoxyadenosines; DNA; DNA Adducts; DNA Damage; Hydrocarbons; Magnetic Resonance Spectroscopy; Models, Statistical; Molecular Conformation; Neoplasms; Nucleic Acid Conformation; Phenanthrenes; Stereoisomerism; Thermodynamics | 2004 |
Accommodation of a 1S-(-)-benzo[c]phenanthrenyl-N6-dA adduct in the Y-family Dpo4 DNA polymerase active site: structural insights through molecular dynamics simulations.
Topics: Carcinogens; Computer Simulation; DNA Adducts; DNA Polymerase beta; Models, Molecular; Phenanthrenes | 2005 |
Structure/reactivity relationships in the benzo[c]phenanthrene skeleton: stable ion and electrophilic substitution (nitration, bromination) study of substituted analogues, novel carbocations and substituted derivatives.
Topics: Bromine Compounds; Chemistry, Organic; Crystallography, X-Ray; Ions; Magnetic Resonance Spectroscopy; Models, Molecular; Nitrates; Phenanthrenes; Structure-Activity Relationship | 2007 |
3'-Intercalation of a N2-dG 1R-trans-anti-benzo[c]phenanthrene DNA adduct in an iterated (CG)3 repeat.
Topics: CpG Islands; DNA; DNA Adducts; Genes, Bacterial; Intercalating Agents; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagens; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Phenanthrenes; Salmonella typhimurium; Sequence Deletion | 2008 |
Ab initio and experimental studies on structure and vibrational spectra of some partially reduced benzo[c]phenanthrenes.
Topics: Hydrogen Bonding; Models, Chemical; Models, Molecular; Oxidation-Reduction; Phenanthrenes; Spectrophotometry, Infrared; Static Electricity; Vibration | 2009 |
Mutagenicity, stable DNA adducts, and abasic sites induced in Salmonella by phenanthro[3,4-b]- and phenanthro[4,3-b]thiophenes, sulfur analogs of benzo[c]phenanthrene.
Topics: Base Sequence; Binding Sites; DNA Adducts; DNA, Bacterial; Frameshift Mutation; Mutagenicity Tests; Mutagens; Phenanthrenes; Salmonella; Thiophenes | 2009 |
Alteration of development and gene expression induced by in ovo-nanoinjection of 3-hydroxybenzo[c]phenanthrene into Japanese medaka (Oryzias latipes) embryos.
Topics: Animals; Embryo, Nonmammalian; Embryonic Development; Female; Gene Expression Profiling; Injections; Male; Oryzias; Phenanthrenes; Random Allocation; RNA, Messenger; Toxicity Tests; Transcriptome; Water Pollutants, Chemical | 2017 |