Compounds > benzo(c)phenanthrene 3,4-dihydrodiol
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benzo(c)phenanthrene 3,4-dihydrodiol and phenanthrenes

benzo(c)phenanthrene 3,4-dihydrodiol has been researched along with phenanthrenes in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mushtaq, M; Yang, SK1
Conney, AH; Jerina, DM; Levin, W; Ryan, DE; Thakker, DR; Thomas, PE; Yagi, H; Yeh, HJ1
Conney, AH; Croisy-Delcey, M; Ittah, Y; Jerina, DM; Levin, W; Ryan, DE; Thakker, DR; Thomas, PE1
Chang, RL; Conney, AH; Croisy-Delcey, M; Ittah, Y; Jerina, DM; Levin, W; Ryan, DE; Thomas, PE; Wood, AW; Yagi, H1
Chang, RL; Conney, AH; Croisy-Delcey, M; Ittah, Y; Jerina, DM; Levin, W; Sayer, JM; Thakker, DR; Wood, AW; Yagi, H1
Silverman, BD1
Brosh, RM; Driscoll, HC; Jerina, DM; Kroth, H; Matson, SW; Sayer, JM1
Blair, IA; Harvey, RG; Mangal, D; Palackal, NT; Penning, TM; Shultz, CA1

Other Studies

8 other study(ies) available for benzo(c)phenanthrene 3,4-dihydrodiol and phenanthrenes

ArticleYear
Stereoselective metabolism of benzo[c]phenanthrene to the procarcinogenic trans-3,4-dihydrodiol.
    Carcinogenesis, 1987, Volume: 8, Issue:5

    Topics: Animals; Carcinogens; Circular Dichroism; Cytochrome P-450 Enzyme System; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Mutagens; Phenanthrenes; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred Strains; Stereoisomerism

1987
Stereoselective metabolism of the (+)-(S,S)- and (-)-(R,R)-enantiomers of trans-3,4-dihydroxy-3,4-dihydrobenzo[c]-phenanthrene by rat and mouse liver microsomes and by a purified and reconstituted cytochrome P-450 system.
    The Journal of biological chemistry, 1986, Apr-25, Volume: 261, Issue:12

    Topics: Animals; Circular Dichroism; Cytochrome P-450 Enzyme System; Female; Isoenzymes; Magnetic Resonance Spectroscopy; Male; Mice; Microsomes, Liver; Phenanthrenes; Rats; Spectrophotometry, Ultraviolet; Stereoisomerism

1986
Metabolism of benzo[c]phenanthrene by rat liver microsomes and by a purified monooxygenase system reconstituted with different isozymes of cytochrome P-450.
    Chemico-biological interactions, 1983, Jul-01, Volume: 45, Issue:1

    Topics: Animals; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Phenanthrenes; Phenobarbital; Phenols; Rats; Stereoisomerism

1983
Mutagenicity of the dihydrodiols and bay-region diol-epoxides of benzo(c)phenanthrene in bacterial and mammalian cells.
    Cancer research, 1980, Volume: 40, Issue:8 Pt 1

    Topics: Animals; Biotransformation; Cell Line; Cell Survival; Cells, Cultured; Cricetinae; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Microsomes, Liver; Mutagens; Phenanthrenes; Rats; Salmonella typhimurium; Structure-Activity Relationship

1980
Highly tumorigenic bay-region diol epoxides from the weak carcinogen benzo[c]phenanthrene.
    Advances in experimental medicine and biology, 1981, Volume: 136 Pt A

    Topics: Animals; Biotransformation; Carcinogens; Chemical Phenomena; Chemistry; Epoxy Compounds; Ethers, Cyclic; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Phenanthrenes; Rats; Salmonella typhimurium; Structure-Activity Relationship

1981
Steric crowding and conformer stability of the diol-epoxides of benzo(c)phenanthrene.
    Cancer biochemistry biophysics, 1982, Volume: 6, Issue:1

    Topics: Epoxy Compounds; Models, Molecular; Molecular Conformation; Phenanthrenes; Structure-Activity Relationship

1982
Inhibition of Werner syndrome helicase activity by benzo[c]phenanthrene diol epoxide dA adducts in DNA is both strand-and stereoisomer-dependent.
    The Journal of biological chemistry, 2003, Oct-17, Volume: 278, Issue:42

    Topics: Adenosine Triphosphatases; Animals; Baculoviridae; Binding, Competitive; DNA; DNA Adducts; DNA Helicases; Dose-Response Relationship, Drug; Escherichia coli; Exodeoxyribonucleases; Humans; Hydrolysis; Insecta; Kinetics; Models, Chemical; Oligonucleotides; Phenanthrenes; Protein Transport; Recombinant Proteins; RecQ Helicases; Stereoisomerism; Werner Syndrome Helicase

2003
Fjord-region benzo[g]chrysene-11,12-dihydrodiol and benzo[c]phenanthrene-3,4-dihydrodiol as substrates for rat liver dihydrodiol dehydrogenase (AKR1C9): structural basis for stereochemical preference.
    Chemical research in toxicology, 2008, Volume: 21, Issue:3

    Topics: Alanine; Alcohol Oxidoreductases; Animals; Chromatography, High Pressure Liquid; Chrysenes; Circular Dichroism; Humans; In Vitro Techniques; Indicators and Reagents; Kinetics; Liver; Mass Spectrometry; Mercaptoethanol; Models, Molecular; Mutation; Oxidoreductases; Phenanthrenes; Rats; Rats, Inbred F344; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity

2008