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benzo(a)pyrene-7,8-dione and deoxyguanosine

benzo(a)pyrene-7,8-dione has been researched along with deoxyguanosine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's5 (71.43)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harvey, RG; Penning, TM; Shou, M1
Blair, IA; McCoull, KD; Penning, TM; Rindgen, D1
Kawanishi, S; Ohnishi, S1
Gao, D; Goldwyn, B; Guevara, D; Lebwohl, M; Lu, Y; Luo, Y; Rui, M; Smith, EC; Wang, Y; Wei, H1
Harvey, RG; Park, JH; Penning, TM; Troxel, AB1
Blair, IA; Harvey, RG; Mangal, D; Park, JH; Penning, TM; Quinn, AM; Tacka, KA1
Blair, IA; Frey, AJ; Harvey, RG; Mangal, D; Park, JH; Penning, TM1

Other Studies

7 other study(ies) available for benzo(a)pyrene-7,8-dione and deoxyguanosine

ArticleYear
Reactivity of benzo[a]pyrene-7,8-dione with DNA. Evidence for the formation of deoxyguanosine adducts.
    Carcinogenesis, 1993, Volume: 14, Issue:3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Benzopyrenes; Cattle; Deoxyguanosine; DNA; DNA Adducts; Estrogens, Catechol

1993
Synthesis and characterization of polycyclic aromatic hydrocarbon o-quinone depurinating N7-guanine adducts.
    Chemical research in toxicology, 1999, Volume: 12, Issue:3

    Topics: Animals; Benzopyrenes; Cattle; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; Magnetic Resonance Spectroscopy; Mass Spectrometry; Naphthalenes; Phenanthrenes; Spectrophotometry, Ultraviolet

1999
Double base lesions of DNA by a metabolite of carcinogenic benzo[a]pyrene.
    Biochemical and biophysical research communications, 2002, Jan-18, Volume: 290, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Benzopyrenes; Binding Sites; Carcinogens; Cattle; Copper; Cyclin-Dependent Kinase Inhibitor p16; Deoxyguanosine; DNA; DNA Damage; DNA-Formamidopyrimidine Glycosylase; Free Radical Scavengers; Genes, p53; Genes, ras; Humans; N-Glycosyl Hydrolases; NAD; Oxidation-Reduction; Piperidines

2002
Benzo[a]pyrene and its metabolites combined with ultraviolet A synergistically induce 8-hydroxy-2'-deoxyguanosine via reactive oxygen species.
    Free radical biology & medicine, 2005, Nov-01, Volume: 39, Issue:9

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; 8-Hydroxy-2'-Deoxyguanosine; Animals; Benzo(a)pyrene; Benzopyrenes; Deoxyguanosine; DNA; DNA Damage; Female; Mice; Mice, Inbred Strains; Microsomes; Reactive Oxygen Species; Singlet Oxygen; Superoxides; Ultraviolet Rays

2005
Polycyclic aromatic hydrocarbon (PAH) o-quinones produced by the aldo-keto-reductases (AKRs) generate abasic sites, oxidized pyrimidines, and 8-oxo-dGuo via reactive oxygen species.
    Chemical research in toxicology, 2006, Volume: 19, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Benz(a)Anthracenes; Benzopyrenes; Copper; Deoxyguanosine; DNA; DNA Adducts; Iron; Oxidation-Reduction; Pyrimidines; Reactive Oxygen Species

2006
Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, May-13, Volume: 105, Issue:19

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Benzopyrenes; Biotransformation; Catechol O-Methyltransferase Inhibitors; Cell Line, Tumor; Comet Assay; Deoxyguanosine; Dihydroxydihydrobenzopyrenes; DNA Breaks, Double-Stranded; DNA Glycosylases; Enzyme Inhibitors; Fluoresceins; Fluorescence; Humans; Isoenzymes; Lung; Oxidation-Reduction; Reactive Oxygen Species; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2008
Aryl hydrocarbon receptor facilitates DNA strand breaks and 8-oxo-2'-deoxyguanosine formation by the aldo-keto reductase product benzo[a]pyrene-7,8-dione.
    The Journal of biological chemistry, 2009, Oct-23, Volume: 284, Issue:43

    Topics: 8-Hydroxy-2'-Deoxyguanosine; alpha-Tocopherol; Animals; Antioxidants; Basic Helix-Loop-Helix Transcription Factors; Benzopyrenes; Cell Line; Cell Line, Tumor; Deferoxamine; Deoxyguanosine; DNA Breaks; DNA Glycosylases; Humans; Mice; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Siderophores

2009