Page last updated: 2024-08-17

benzimidazole and thiophenes

benzimidazole has been researched along with thiophenes in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (87.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Herling, AW; Kohlmann, M; Matter, H; Namane, C; Pfenninger, A; Philippo, C; Sanchez-Arias, JA; Voss, MD; Zoller, G1
Famulok, M; Halls, V; Hannam, JS; Hoerauf, A; Lentz, CS; Mayer, G; Niebel, B; Pfarr, KM; Strübing, U1
Bandholtz, S; Goebel, M; Gust, R; Herbst, L; Kintscher, U1
Baltaş, N; Bekircan, O; Kahveci, B; Menteşe, E; Yılmaz, F1
Chung, H; David Pessoa-Mahana, C; Di Marzo, V; Faúndez, M; Lagos, CF; Lorca, M; Mella, J; Morales-Verdejo, C; Romero-Parra, J; Tapia, RA1
Boykin, DW; Farahat, AA; Guo, P; Harika, NK; Kumar, A; Paul, A; Wang, S; Wilson, WD1
Abdallah, AEM; Mohamed, AA; Mohareb, RM1
Boykin, DW; Farahat, AA; Guo, P; Kumar, A; Paul, A; Wilson, WD1

Other Studies

8 other study(ies) available for benzimidazole and thiophenes

ArticleYear
Benzimidazole-carboxamides as potent and bioavailable stearoyl-CoA desaturase (SCD1) inhibitors from ligand-based virtual screening and chemical optimization.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Amides; Animals; Benzimidazoles; Biological Availability; Caco-2 Cells; Enzyme Inhibitors; Half-Life; Humans; Ligands; Male; Mice; Protein Binding; Rats; Rats, Zucker; Stearoyl-CoA Desaturase; Structure-Activity Relationship; Thiophenes

2013
A selective inhibitor of heme biosynthesis in endosymbiotic bacteria elicits antifilarial activity in vitro.
    Chemistry & biology, 2013, Feb-21, Volume: 20, Issue:2

    Topics: Animals; Antiprotozoal Agents; Benzimidazoles; Drug Design; Elephantiasis, Filarial; Filarioidea; Heme; High-Throughput Screening Assays; Humans; Kinetics; Magnesium; Porphobilinogen Synthase; Symbiosis; Thiophenes; Wolbachia

2013
Characterization of telmisartan-derived PPARγ agonists: importance of moiety shift from position 6 to 5 on potency, efficacy and cofactor recruitment.
    ChemMedChem, 2012, Volume: 7, Issue:11

    Topics: 3T3-L1 Cells; Animals; Benzimidazoles; Benzoates; Benzofurans; Chlorocebus aethiops; COS Cells; Diabetes Mellitus, Type 2; Humans; Ligands; Mice; PPAR gamma; Structure-Activity Relationship; Telmisartan; Thiophenes

2012
Synthesis and antioxidant activities of some new triheterocyclic compounds containing benzimidazole, thiophene, and 1,2,4-triazole rings.
    Journal of enzyme inhibition and medicinal chemistry, 2015, Volume: 30, Issue:3

    Topics: Antioxidants; Benzimidazoles; Dose-Response Relationship, Drug; Heterocyclic Compounds; Molecular Structure; Structure-Activity Relationship; Thiophenes; Triazoles

2015
Combined CoMFA and CoMSIA 3D-QSAR study of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Apr-01, Volume: 101

    Topics: Benzimidazoles; Cannabinoids; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Static Electricity; Thiophenes

2017
A modular design for minor groove binding and recognition of mixed base pair sequences of DNA.
    Chemical communications (Cambridge, England), 2017, Sep-25, Volume: 53, Issue:75

    Topics: Base Pairing; Base Sequence; Benzimidazoles; Binding Sites; DNA; Molecular Structure; Thiophenes

2017
Synthesis of Novel Thiophene, Thiazole and Coumarin Derivatives Based on Benzimidazole Nucleus and Their Cytotoxicity and Toxicity Evaluations.
    Chemical & pharmaceutical bulletin, 2018, Volume: 66, Issue:3

    Topics: Anilides; Animals; Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Coumarins; Decapoda; Drug Screening Assays, Antitumor; Humans; Larva; Quinolines; Structure-Activity Relationship; Thiazoles; Thiophenes

2018
Extending the σ-Hole Motif for Sequence-Specific Recognition of the DNA Minor Groove.
    Biochemistry, 2020, 05-12, Volume: 59, Issue:18

    Topics: Amidines; Base Pairing; Benzimidazoles; DNA; Humans; Molecular Structure; Thiophenes

2020