Compounds > benzimidazole
Page last updated: 2024-08-17

benzimidazole and pyrimidine

benzimidazole has been researched along with pyrimidine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brugel, TA; De, B; Easwaran, V; Evdokimov, A; Golebiowski, A; Hsieh, LC; Janusz, MJ; Laufersweiler, MJ; Maier, J; Mekel, MJ; Sabat, M; VanRens, JC; Walter, RL1
El-Gendy, Bel-D; Ghiviriga, I; Katritzky, AR; Steel, PJ1
Abdel-Mohsen, HT; El Diwani, HI; Ragab, FA; Ramla, MM1
Dhamanage, A; Kulkarni, S; Singh, A; Singh, RK; Yadav, D; Yadav, M1
Attia, YM; El Abd, YS; El Diwani, HI; El-Rashedy, AA; El-Shenawy, R; Galal, SA; Kandil, OM; Khattab, M; Ramadan, R; Shouman, SA; Tabll, A1
Abdelgawad, MA; Ahmad, W; Al-Sanea, MM; Bakr, RB; Elshemy, HAH1

Other Studies

6 other study(ies) available for benzimidazole and pyrimidine

ArticleYear
The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck).
    Bioorganic & medicinal chemistry letters, 2006, Dec-01, Volume: 16, Issue:23

    Topics: Benzimidazoles; Hydrogen Bonding; Inhibitory Concentration 50; Interleukin-2; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-hck; Pyrimidines; Structure-Activity Relationship

2006
Tautomerism of guanidines studied by (15)N NMR: 2-hydrazono-3-phenylquinazolin-4(3H)-ones and related compounds.
    Organic & biomolecular chemistry, 2009, Oct-07, Volume: 7, Issue:19

    Topics: Analgesics; Anti-Inflammatory Agents; Benzimidazoles; Crystallography, X-Ray; Drug Discovery; Guanine; Hydrazines; Isomerism; Magnetic Resonance Spectroscopy; Pyrimidines; Quinazolinones

2009
Novel benzimidazole-pyrimidine conjugates as potent antitumor agents.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:6

    Topics: Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Humans; Lethal Dose 50; Pyrimidines

2010
Molecular modeling, synthesis and biological evaluation of N-heteroaryl compounds as reverse transcriptase inhibitors against HIV-1.
    Chemical biology & drug design, 2015, Volume: 85, Issue:3

    Topics: Benzimidazoles; Binding Sites; Catalytic Domain; Cell Line; Cell Survival; Drug Design; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication

2015
Part III: Novel checkpoint kinase 2 (Chk2) inhibitors; design, synthesis and biological evaluation of pyrimidine-benzimidazole conjugates.
    European journal of medicinal chemistry, 2018, Feb-25, Volume: 146

    Topics: Benzimidazoles; Cell Cycle; Cell Proliferation; Checkpoint Kinase 2; Dose-Response Relationship, Drug; Drug Design; Humans; MCF-7 Cells; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Pyrimidines; Structure-Activity Relationship

2018
New pyrimidine-benzoxazole/benzimidazole hybrids: Synthesis, antioxidant, cytotoxic activity, in vitro cyclooxygenase and phospholipase A2-V inhibition.
    Bioorganic chemistry, 2019, Volume: 92

    Topics: Antineoplastic Agents; Antioxidants; Benzimidazoles; Benzoxazoles; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Group V Phospholipases A2; Humans; Molecular Docking Simulation; Molecular Structure; Phospholipase A2 Inhibitors; Picrates; Pyrimidines; Structure-Activity Relationship

2019