Page last updated: 2024-08-17

benzimidazole and pyrazole

benzimidazole has been researched along with pyrazole in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's7 (63.64)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Kulys, J; Tetianec, L; Ziemys, A1
Abdullah, MM; Bakht, MA; Majeed, J; Shaharyar, M1
Cheng, HB; Guo, J; Li, WJ; Ren, TG; Yang, LR; Zhang, JL1
Huynh, HV; Sivaram, H; Tan, J1
Abdelgawad, MA; Bakr, RB; Omar, HA1
Abdel-Halim, AH; Ali, HI; Ali, MM; Attia, YM; El Abd, YS; El Diwani, HI; El-Shenawy, R; Fyiad, AA; Galal, SA; Khairat, SHM; Mahmoud, AE; Ramdan, R; Shouman, SA; Tabll, A1
Liu, CH; Shi, TQ; Wang, YT; Zhu, HL1
Akter, M; Debono, CO; Devine, SM; Drew, SC; Drinkwater, N; Krishnarjuna, B; MacRaild, CA; McGowan, S; Norton, RS; Scammells, PJ; Scanlon, MJ; Wang, G1
Ahmad, M; Ashfaq, UA; Aslam, S; Ibraheem, F; Khan, ZA; Sultan, S1
Dubiel, K; Dzwonek, K; Hucz-Kalitowska, J; Lamparska-Przybysz, M; Lipner, J; Magdycz, M; Olejkowska, P; Pieczykolan, J; Piórkowska, N; Popiel, D; Stańczak, A; Stańczak, PS; Wieczorek, M; Yamani, A; Zdżalik-Bielecka, D1
Carter, DM; Dudaniec, K; Gohlke, U; Heinemann, U; Małecki, PH; Nazaré, M; Przygodda, J; Specker, E; Weiss, MS1

Reviews

1 review(s) available for benzimidazole and pyrazole

ArticleYear
Discovery and optimization of novel pyrazole-benzimidazole CPL304110, as a potent and selective inhibitor of fibroblast growth factor receptors FGFR (1-3).
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Antineoplastic Agents; Benzimidazoles; Cell Proliferation; Drug Discovery; Humans; Protein Kinase Inhibitors; Pyrazoles; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 3

2021

Other Studies

10 other study(ies) available for benzimidazole and pyrazole

ArticleYear
Probing Aspergillus niger glucose oxidase with pentacyanoferrate(III) aza- and thia-complexes.
    Journal of inorganic biochemistry, 2006, Volume: 100, Issue:10

    Topics: Aspergillus niger; Benzimidazoles; Ferric Compounds; Glucose Oxidase; Histidine; Imidazoles; Models, Chemical; Models, Molecular; Oxidation-Reduction; Pyrazoles; Pyridines; Structure-Activity Relationship; Thiadiazoles; Triazoles

2006
Pyrazoline bearing benzimidazoles: search for anticancer agent.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:1

    Topics: Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Discovery; Humans; Pyrazoles

2010
Synthesis of benzimidazoles containing pyrazole group and quantum chemistry calculation of their spectroscopic properties and electronic structure.
    Journal of fluorescence, 2012, Volume: 22, Issue:1

    Topics: Absorption; Benzimidazoles; Electrons; Models, Molecular; Molecular Conformation; Pyrazoles; Quantum Theory; Spectrum Analysis

2012
Cationic gold(I) heteroleptic complexes bearing a pyrazole-derived N-heterocyclic carbene: syntheses, characterizations, and cytotoxic activities.
    Dalton transactions (Cambridge, England : 2003), 2013, Sep-14, Volume: 42, Issue:34

    Topics: Benzimidazoles; Cell Line, Tumor; Cell Survival; Coordination Complexes; Gold; Heterocyclic Compounds; Humans; Ligands; Methane; Molecular Conformation; Pyrazoles

2013
Design, synthesis and biological evaluation of some novel benzothiazole/benzoxazole and/or benzimidazole derivatives incorporating a pyrazole scaffold as antiproliferative agents.
    Bioorganic chemistry, 2017, Volume: 74

    Topics: Antineoplastic Agents; Benzimidazoles; Benzothiazoles; Benzoxazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Pyrazoles; Structure-Activity Relationship

2017
Part II: New candidates of pyrazole-benzimidazole conjugates as checkpoint kinase 2 (Chk2) inhibitors.
    European journal of medicinal chemistry, 2018, Jan-20, Volume: 144

    Topics: Animals; Antineoplastic Agents; Benzimidazoles; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 2; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Pyrazoles; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

2018
Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
    Bioorganic & medicinal chemistry, 2019, 02-01, Volume: 27, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzimidazoles; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HEK293 Cells; Hepatocytes; Humans; Mice; Molecular Docking Simulation; Molecular Structure; Polymerization; Pyrazoles; Structure-Activity Relationship; Sulfonamides; Tubulin; Tubulin Modulators

2019
Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe.
    ChemMedChem, 2019, 03-05, Volume: 14, Issue:5

    Topics: Amino Acid Sequence; Antigens, Protozoan; Benzimidazoles; Binding Sites; Cell Membrane; Crystallography, X-Ray; Furans; Hydrophobic and Hydrophilic Interactions; Ligands; Magnetic Resonance Spectroscopy; Membrane Proteins; Models, Molecular; Molecular Probes; Molecular Structure; Peptides; Protein Binding; Protozoan Proteins; Pyrazoles; Pyrimidines; Pyrroles; Quinazolinones; Structure-Activity Relationship; Sulfonamides

2019
Synthesis, molecular docking and anti-diabetic studies of novel benzimidazole-pyrazoline hybrid molecules.
    Pakistan journal of pharmaceutical sciences, 2020, Volume: 33, Issue:2(Suppleme

    Topics: Benzaldehydes; Benzimidazoles; Chalcones; Hydrazines; Hypoglycemic Agents; Molecular Docking Simulation; Pyrazoles; Structure-Activity Relationship

2020
Enhanced Properties of a Benzimidazole Benzylpyrazole Lysine Demethylase Inhibitor: Mechanism-of-Action, Binding Site Analysis, and Activity in Cellular Models of Prostate Cancer.
    Journal of medicinal chemistry, 2021, 10-14, Volume: 64, Issue:19

    Topics: Benzimidazoles; Binding Sites; Cell Survival; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Jumonji Domain-Containing Histone Demethylases; Models, Molecular; Molecular Structure; Pyrazoles; Structure-Activity Relationship; Tumor Cells, Cultured

2021