Page last updated: 2024-08-17

benzimidazole and indole

benzimidazole has been researched along with indole in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's3 (25.00)29.6817
2010's7 (58.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Bernstein, PR; Brown, FJ; Cronk, LA; Krell, RD; Maduskuie, TP; Matassa, VG; Shapiro, HS; Snyder, DW; Vacek, EP; Yee, YK1
Bánhegyi, P; Erös, D; Hafenbradl, D; Hegymegi-Barakonyi, B; Hollósy, F; Kéri, G; Klebl, B; Mészáros, G; Obert, S; Orfi, L; Pató, J; Székelyhidi, Z; Wáczek, F1
Borges, F; Chavarria, D; Fernandes, C; Gil-Martins, E; Oliveira, PJ; Remião, F; Silva, C; Silva, R; Silva, T; Silva, V; Soares, P1
Dunn, MF; Ferrari, D; Miles, EW; Yang, LH1
Algul, O; Apcin, Y; Jose, J; Kaessler, A; Yilmaz, A1
Baker, L; Bryant, CJ; Davis, B; Dokurno, P; Gueritz, L; Matassova, N; Moore, JD; Murray, JB; Nunns, CL; Potter, AJ; Ray, S; Richardson, CM; Robinson, DA; Scrace, SF; Surgenor, AE1
Cesarini, S; Cichero, E; Fossa, P; Mosti, L1
Baker, J; Cowley, P; Edwards, D; Ho, KK; Jokiel, P; Letourneau, JJ; McAleer, L; Ohlmeyer, MH; Olson, J; Riviello, CM; Swanson, RN; Ward, N; Webb, ML; Yang, J1
Jiang, Y; Li, H; Ni, J; Xing, X; Zhu, X1
Angerer, V; Auwärter, V; Bisel, P; Hess, C; Huppertz, LM; Mogler, L; Müller, CE; Schäper, J; Schoeder, CT; Steitz, JP; Westphal, F1
Boykin, DW; Brun, R; Farahat, AA; Ismail, MA; Kumar, A; Paul, A; Wenzler, T; Wilson, WD1
Dhiman, M; Gupta, KB; Jaitak, V; Singla, R; Upadhyay, S1

Other Studies

12 other study(ies) available for benzimidazole and indole

ArticleYear
Synthesis and in vitro LTD4 antagonist activity of bicyclic and monocyclic cyclopentylurethane and cyclopentylacetamide N-arylsulfonyl amides.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:9

    Topics: Animals; Benzimidazoles; Chemical Phenomena; Chemistry; Guinea Pigs; Indoles; Muscle, Smooth; Phenylcarbamates; Receptors, Immunologic; Receptors, Leukotriene; SRS-A; Structure-Activity Relationship; Sulfonamides; Thiophenes; Tosyl Compounds

1990
Synthesis of selective SRPK-1 inhibitors: novel tricyclic quinoxaline derivatives.
    Bioorganic & medicinal chemistry letters, 2005, Jul-01, Volume: 15, Issue:13

    Topics: Antiviral Agents; Enzyme Inhibitors; Hepatitis B; Hepatitis B virus; Humans; Inhibitory Concentration 50; Protein Serine-Threonine Kinases; Quinoxalines; Structure-Activity Relationship

2005
Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies.
    European journal of medicinal chemistry, 2020, Jan-01, Volume: 185

    Topics: Alkaloids; Benzodioxoles; Caco-2 Cells; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Humans; Ligands; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Oxidative Stress; Piperidines; Polyunsaturated Alkamides; Structure-Activity Relationship; Tumor Cells, Cultured

2020
Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity.
    Biochemistry, 2001, Jun-26, Volume: 40, Issue:25

    Topics: Alanine; Allosteric Regulation; Aniline Compounds; Aspartic Acid; Benzimidazoles; beta-Alanine; Catalysis; Deuterium; Enzyme Activation; Hydroxylamines; Indoles; Kinetics; Multienzyme Complexes; Mutagenesis, Site-Directed; Pyruvic Acid; Salmonella typhimurium; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity; Titrimetry; Tryptophan Synthase

2001
Comparative studies on conventional and microwave synthesis of some benzimidazole, benzothiazole and indole derivatives and testing on inhibition of hyaluronidase.
    Molecules (Basel, Switzerland), 2008, Mar-27, Volume: 13, Issue:4

    Topics: Animals; Benzimidazoles; Benzothiazoles; Cattle; Enzyme Inhibitors; Hyaluronoglucosaminidase; Hydrogen-Ion Concentration; Indoles; Microwaves

2008
Structure-guided design of alpha-amino acid-derived Pin1 inhibitors.
    Bioorganic & medicinal chemistry letters, 2010, Jan-15, Volume: 20, Issue:2

    Topics: Amino Acids; Antineoplastic Agents; Benzimidazoles; Binding Sites; Cell Line, Tumor; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Hydrogen Bonding; Indoles; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Structure-Activity Relationship

2010
CoMFA and CoMSIA analyses on 1,2,3,4-tetrahydropyrrolo[3,4-b]indole and benzimidazole derivatives as selective CB2 receptor agonists.
    Journal of molecular modeling, 2010, Volume: 16, Issue:9

    Topics: Benzimidazoles; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Indoles; Models, Molecular; Pyrazoles; Quantitative Structure-Activity Relationship; Receptor, Cannabinoid, CB2; Static Electricity; Thermodynamics

2010
Identification and hit-to-lead optimization of a novel class of CB1 antagonists.
    Bioorganic & medicinal chemistry letters, 2010, Sep-15, Volume: 20, Issue:18

    Topics: Animals; Benzimidazoles; Humans; Hypothermia; Indoles; Male; Mice; Microsomes, Liver; Obesity; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Solubility; Structure-Activity Relationship

2010
Electrochemical oxidation of nitrogen-heterocyclic compounds at boron-doped diamond electrode.
    Chemosphere, 2012, Volume: 86, Issue:4

    Topics: Benzimidazoles; Boron; Diamond; Electrochemical Techniques; Electrodes; Heterocyclic Compounds; Hydroxyl Radical; Indoles; Isoquinolines; Nitrogen; Oxidation-Reduction; Quinolines; Triazoles; Waste Disposal, Fluid; Water Pollutants, Chemical

2012
Structural characterization and pharmacological evaluation of the new synthetic cannabinoid CUMYL-PEGACLONE.
    Drug testing and analysis, 2018, Volume: 10, Issue:3

    Topics: Animals; Benzimidazoles; Cannabinoids; CHO Cells; Cricetulus; Designer Drugs; Humans; Illicit Drugs; Indazoles; Indoles; Psychotropic Drugs; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2

2018
Indole and Benzimidazole Bichalcophenes: Synthesis, DNA Binding and Antiparasitic Activity.
    European journal of medicinal chemistry, 2018, Jan-01, Volume: 143

    Topics: Animals; Benzimidazoles; Cell Survival; Disease Models, Animal; Indoles; Mice; Parasitic Sensitivity Tests; Pentamidine; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2018
Design, synthesis and biological evaluation of novel indole-benzimidazole hybrids targeting estrogen receptor alpha (ER-α).
    European journal of medicinal chemistry, 2018, Feb-25, Volume: 146

    Topics: Antineoplastic Agents; Benzimidazoles; Cell Proliferation; Cell Survival; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Estrogen Receptor alpha; Humans; Indoles; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured

2018