Page last updated: 2024-08-17

benzimidazole and benzoxazoles

benzimidazole has been researched along with benzoxazoles in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (13.64)29.6817
2010's16 (72.73)24.3611
2020's3 (13.64)2.80

Authors

AuthorsStudies
Das, J; Iqbal, J; Khadeer, A; Kumar, MS; Mallik, A; Rao, CV; Roshaiah, M; Sankar, PG; Sastry, TV; Selvakumar, N; Trehan, S1
Kumar, A; Lozach, O; Meijer, L; Singh, N; Sondhi, SM1
Ahmad, P; Kumar, A; Maurya, RA1
Cellier, M; Fabrega, OJ; Fazackerley, E; James, AL; Orenga, S; Perry, JD; Salwatura, VL; Stanforth, SP1
Gupta, VD; Padalkar, VS; Patil, VS; Phatangare, K; Sekar, N; Tathe, A1
Liu, G; Yan, Y; Zhao, N; Zhong, Q1
Chibale, K; Gut, J; Masimirembwa, CM; Ongarora, DS; Rosenthal, PJ1
Gophane, DB; Sigurdsson, ST1
Chen, CH; Liao, JY; Selvaraju, M; Sun, CM1
Adepu, R; Chintala, S; Kapavarapu, R; Meda, CL; Pal, M; Parsa, KV; Sunke, R1
Krishna, NS; Padmaja, A; Padmavathi, V; Reddy, GM; Reddy, PR; Seenaiah, D1
Carato, P; Donnier-Maréchal, M; Furman, C; Le Broc, D; Melnyk, P1
Abdelgawad, MA; Bakr, RB; Omar, HA1
Augustynowicz-Kopeć, E; Foks, H; Gobis, K; Krause, M; Napiórkowska, A; Szczesio, M1
Chaudhari, HK; Ghanavatkar, CW; Mali, SN; Mishra, VR; Qureshi, SI; Sekar, N1
Jin, Y; Li, K; Li, L; Lin, J; Liu, F; Wu, D; Xie, M; Zhang, C; Zhang, D; Zhang, J; Zhang, Z; Zhu, C; Zi, M1
Jin, Y; Li, K; Li, L; Lin, J; Liu, T; Liu, Y; Xie, M; Yang, Q; Yuan, X; Zhang, C; Zhang, J; Zhang, Z; Zhu, C1
Dadashpour, S; Ercan, A; Hosseinimehr, SJ; Irannejad, H; Küçükkılınç, TT; Naderi, N1
Abdelgawad, MA; Ahmad, W; Al-Sanea, MM; Bakr, RB; Elshemy, HAH1
Ha, EH; Hu, Q; Li, H; Li, Z; Pang, J; Tian, S; Wang, W; Zhou, M1
Baker-Agha, A; Franz, KJ; Jackson, AC; Patel, D; Pinter, TBJ; Smith, PJ; Talley, DC1
Fery-Forgues, S; Vanucci-Bacqué, C1

Reviews

1 review(s) available for benzimidazole and benzoxazoles

ArticleYear
Recent Trends in the Design, Synthesis, Spectroscopic Behavior, and Applications of Benzazole-Based Molecules with Solid-State Luminescence Enhancement Properties.
    Topics in current chemistry (Cham), 2021, Aug-03, Volume: 379, Issue:5

    Topics: Azoles; Benzimidazoles; Benzothiazoles; Benzoxazoles; Luminescent Measurements; Phenothiazines; Schiff Bases; Stilbenes

2021

Other Studies

21 other study(ies) available for benzimidazole and benzoxazoles

ArticleYear
Effects of positional and geometrical isomerism on the biological activity of some novel oxazolidinones.
    Bioorganic & medicinal chemistry letters, 2005, Jan-17, Volume: 15, Issue:2

    Topics: Acetamides; Anti-Infective Agents; Bacteria; Benzimidazoles; Benzoxazoles; Isomerism; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Structure-Activity Relationship; Thioacetamide; Triazoles

2005
Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff's bases.
    Bioorganic & medicinal chemistry, 2006, Jun-01, Volume: 14, Issue:11

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; Benzoxazoles; CDC2 Protein Kinase; Cyclin-Dependent Kinase 5; Drug Evaluation, Preclinical; Enzyme Activation; Female; Glycogen Synthase Kinase 3; Mice; Protein Kinases; Rats; Rats, Wistar; Schiff Bases; Structure-Activity Relationship

2006
Diversity oriented synthesis of benzimidazole and benzoxa/(thia)zole libraries through polymer-supported hypervalent iodine reagent.
    Journal of combinatorial chemistry, 2009, Mar-09, Volume: 11, Issue:2

    Topics: Benzimidazoles; Benzoxazoles; Iodine; Polymers; Small Molecule Libraries

2009
2-Arylbenzothiazole, benzoxazole and benzimidazole derivatives as fluorogenic substrates for the detection of nitroreductase and aminopeptidase activity in clinically important bacteria.
    Bioorganic & medicinal chemistry, 2011, May-01, Volume: 19, Issue:9

    Topics: Aminopeptidases; Bacteria; Benzimidazoles; Benzothiazoles; Benzoxazoles; Fluorescent Dyes; Nitroreductases; Substrate Specificity

2011
Synthesis and photo-physical characteristics of ESIPT inspired 2-substituted benzimidazole, benzoxazole and benzothiazole fluorescent derivatives.
    Journal of fluorescence, 2012, Volume: 22, Issue:1

    Topics: Absorption; Benzimidazoles; Benzothiazoles; Benzoxazoles; Fluorescent Dyes; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Quantum Theory; Solvents; Temperature; Viscosity

2012
First cascade Mitsunobu reactions for the synthesis of 2-benzoxazole-N-phenyl and 2-benzimidazole-N-phenyl derivatives.
    Molecular diversity, 2012, Volume: 16, Issue:1

    Topics: Benzimidazoles; Benzoxazoles; Chemistry, Organic; Crystallography, X-Ray; Dabigatran; Indicators and Reagents; Isomerism; Models, Chemical; Pyridines

2012
Benzoheterocyclic amodiaquine analogues with potent antiplasmodial activity: synthesis and pharmacological evaluation.
    Bioorganic & medicinal chemistry letters, 2012, Aug-01, Volume: 22, Issue:15

    Topics: Amodiaquine; Animals; Antimalarials; Benzimidazoles; Benzothiazoles; Benzoxazoles; Cell Line; Drug Resistance, Microbial; Heterocyclic Compounds; Plasmodium falciparum; Pyridines; Rats; Structure-Activity Relationship

2012
Hydrogen-bonding controlled rigidity of an isoindoline-derived nitroxide spin label for nucleic acids.
    Chemical communications (Cambridge, England), 2013, Feb-01, Volume: 49, Issue:10

    Topics: Benzimidazoles; Benzoxazoles; DNA; Hydrogen Bonding; Isoindoles; Molecular Structure; Spin Labels

2013
Multistep divergent synthesis of benzimidazole linked benzoxazole/benzothiazole via copper catalyzed domino annulation.
    Organic & biomolecular chemistry, 2013, Apr-21, Volume: 11, Issue:15

    Topics: Benzimidazoles; Benzothiazoles; Benzoxazoles; Catalysis; Chemistry Techniques, Synthetic; Copper

2013
Vinylic amino group activation: a new and general strategy leading to functionalized fused heteroaromatics.
    Chemical communications (Cambridge, England), 2013, May-04, Volume: 49, Issue:34

    Topics: Benzimidazoles; Benzoxazoles; Cyclization; Ion Exchange Resins; Isoquinolines; Phosphodiesterase 4 Inhibitors; Styrenes

2013
Synthesis, antimicrobial and cytotoxic activities of pyrimidinyl benzoxazole, benzothiazole and benzimidazole.
    European journal of medicinal chemistry, 2014, Apr-22, Volume: 77

    Topics: Anti-Bacterial Agents; Antifungal Agents; Benzimidazoles; Benzothiazoles; Benzoxazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Penicillium chrysogenum; Staphylococcus aureus; Structure-Activity Relationship

2014
Synthesis and pharmacological evaluation of benzannulated derivatives as potent and selective sigma-1 protein ligands.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Benzimidazoles; Benzothiazoles; Benzoxazoles; Cell Line, Tumor; Dose-Response Relationship, Drug; Heterocyclic Compounds; Humans; Hydrocarbons, Brominated; Ligands; Molecular Structure; Receptors, sigma; Structure-Activity Relationship

2015
Design, synthesis and biological evaluation of some novel benzothiazole/benzoxazole and/or benzimidazole derivatives incorporating a pyrazole scaffold as antiproliferative agents.
    Bioorganic chemistry, 2017, Volume: 74

    Topics: Antineoplastic Agents; Benzimidazoles; Benzothiazoles; Benzoxazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Pyrazoles; Structure-Activity Relationship

2017
Synthesis and Tuberculostatic Activity Evaluation of Novel Benzazoles with Alkyl, Cycloalkyl or Pyridine Moiety.
    Molecules (Basel, Switzerland), 2018, Apr-23, Volume: 23, Issue:4

    Topics: Antitubercular Agents; Benzimidazoles; Benzothiazoles; Benzoxazoles; Molecular Structure; Mycobacterium tuberculosis; Pyridines; Structure-Activity Relationship

2018
Design, synthesis, antimicrobial activity and computational studies of novel azo linked substituted benzimidazole, benzoxazole and benzothiazole derivatives.
    Computational biology and chemistry, 2019, Volume: 78

    Topics: Anti-Bacterial Agents; Azo Compounds; Benzimidazoles; Benzothiazoles; Benzoxazoles; Drug Design; Escherichia coli; Microbial Sensitivity Tests; Molecular Docking Simulation; Staphylococcus aureus

2019
Discovery of 6-Arylurea-2-arylbenzoxazole and 6-Arylurea-2-arylbenzimidazole Derivatives as Angiogenesis Inhibitors: Design, Synthesis and in vitro Biological Evaluation.
    ChemMedChem, 2019, 07-03, Volume: 14, Issue:13

    Topics: Angiogenesis Inhibitors; Animals; Benzimidazoles; Benzoxazoles; Binding Sites; Cell Line; Cell Proliferation; Cell Survival; Chickens; Drug Design; Humans; Molecular Docking Simulation; Neovascularization, Physiologic; Protein Structure, Tertiary; Structure-Activity Relationship; Vascular Endothelial Growth Factor Receptor-2

2019
Design, synthesis and in vitro evaluation of 6-amide-2-aryl benzoxazole/benzimidazole derivatives against tumor cells by inhibiting VEGFR-2 kinase.
    European journal of medicinal chemistry, 2019, Oct-01, Volume: 179

    Topics: A549 Cells; Antineoplastic Agents; Benzimidazoles; Benzoxazoles; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Molecular Structure; Protein Kinase Inhibitors; Structure-Activity Relationship; Vascular Endothelial Growth Factor Receptor-2

2019
Synthesis and Anticancer Activity of Benzimidazole/Benzoxazole Substituted Triazolotriazines in Hepatocellular Carcinoma.
    Anti-cancer agents in medicinal chemistry, 2019, Volume: 19, Issue:17

    Topics: Antineoplastic Agents; Benzimidazoles; Benzoxazoles; Carcinoma, Hepatocellular; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Triazines

2019
New pyrimidine-benzoxazole/benzimidazole hybrids: Synthesis, antioxidant, cytotoxic activity, in vitro cyclooxygenase and phospholipase A2-V inhibition.
    Bioorganic chemistry, 2019, Volume: 92

    Topics: Antineoplastic Agents; Antioxidants; Benzimidazoles; Benzoxazoles; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Group V Phospholipases A2; Humans; Molecular Docking Simulation; Molecular Structure; Phospholipase A2 Inhibitors; Picrates; Pyrimidines; Structure-Activity Relationship

2019
Development of novel NLRP3-XOD dual inhibitors for the treatment of gout.
    Bioorganic & medicinal chemistry letters, 2020, 02-15, Volume: 30, Issue:4

    Topics: Animals; Benzimidazoles; Benzoxazoles; Cell Line; Disease Models, Animal; Gout; Humans; Hyperuricemia; Interleukin-1beta; Liver; Mice; Monocytes; NLR Family, Pyrin Domain-Containing 3 Protein; Oxonic Acid; Rats; Structure-Activity Relationship; Synovial Membrane; Uric Acid; Xanthine Oxidase

2020
Benzimidazole and Benzoxazole Zinc Chelators as Inhibitors of Metallo-β-Lactamase NDM-1.
    ChemMedChem, 2021, 02-17, Volume: 16, Issue:4

    Topics: Anti-Bacterial Agents; Benzimidazoles; Benzoxazoles; beta-Lactamases; Chelating Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Zinc

2021