benzene and nadp

benzene has been researched along with nadp in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199016 (61.54)18.7374
1990's3 (11.54)18.2507
2000's3 (11.54)29.6817
2010's4 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jergil, B; Schelin, C; Tunek, A1
Khan, S; Krishnamurthy, R; Pandya, KP1
Brownlee, LJ; Hollebone, BR1
Kitson, FG; Sariaslani, FS; Trower, MK1
Goldstein, BD; Latriano, L; Witz, G1
Blumer, JL; Pellack-Walker, P1
Gonasun, LM; Kocsis, JJ; Snyder, R; Witmer, C1
Sloane, NH1
Heinemann, M; Sloane, NH2
Glende, EA; Recknagel, RO1
Williams, RT1
Kalf, GF; Rushmore, T; Snyder, R1
Kissinger, PT; Lunte, SM1
Smart, RC; Zannoni, VG1
Bus, JS; Greenlee, WF; Sun, JD1
Goldstein, BD; Witz, G; Zhang, Z1
Filipcova, B; Gut, I; Soucek, P1
Gut, I; Soucek, P1
Chen, Y; Li, G; Yin, S1
HATANAKA, M; HAYAISHI, O; KUNO, S; KURIHARA, N; NAKAJIMA, M; TANIUCHI, H1
Kondrová, E; Soucek, P; Stopka, P1
Holden, HM; Kubiak, RL1
Barilleau, L; Fosse, C; Haquette, P; Madern, N; Salmain, M; Talbi, B1
Gerlovina, I; Hubbard, AE; Loguinov, A; North, M; Smith, MT; Tandon, VJ; Thomas, R; Vulpe, CD; Zhang, L1
Kawakami, N; Kunimatsu, T; Shoji, O; Watanabe, Y1

Reviews

2 review(s) available for benzene and nadp

ArticleYear
Hepatic metabolism of drugs.
    Gut, 1972, Volume: 13, Issue:7

    Topics: Animals; Benzene; Biotransformation; Codeine; Cytochromes; Endoplasmic Reticulum; Humans; Kidney; Liver; Mitochondria, Liver; NADP; Pharmaceutical Preparations; Phenacetin; Phenobarbital; Phenols; Serotonin; Thalidomide; Thiopental

1972
[Individual susceptibility to hematotoxicity from benzene exposure and the genetic polymorphism of metabolic enzymes].
    Wei sheng yan jiu = Journal of hygiene research, 2002, Volume: 31, Issue:2

    Topics: Air Pollutants, Occupational; Benzene; Cytochrome P-450 CYP2E1; Genetic Predisposition to Disease; Glutathione Transferase; Humans; Leukemia; NADP; Poisoning; Polymorphism, Genetic

2002

Other Studies

24 other study(ies) available for benzene and nadp

ArticleYear
Microsomal target proteins of metabolically activated aromatic hydrocarbons.
    Chemico-biological interactions, 1979, Volume: 27, Issue:2-3

    Topics: Animals; Benzene; Benzopyrenes; Hydrocarbons; Male; Methylcholanthrene; Microsomes, Liver; NADP; Phenols; Protein Binding; Proteins; Rats; Time Factors; Uridine Diphosphate Glucuronic Acid

1979
Generation of hydroxyl radicals during benzene toxicity.
    Biochemical pharmacology, 1990, Apr-15, Volume: 39, Issue:8

    Topics: Animals; Antioxidants; Benzene; Bone Marrow; Deoxyribose; Dimethyl Sulfoxide; Electron Transport; Female; Formaldehyde; Free Radicals; Hydroxides; Hydroxyl Radical; NADP; Rats; Rats, Inbred Strains

1990
A correlation of induced mixed-function oxidase specific activity to C-H bond strengths in partially chlorinated monocyclic hydrocarbons.
    Journal of applied toxicology : JAT, 1986, Volume: 6, Issue:1

    Topics: Animals; Benzene; Chemical Phenomena; Chemistry, Physical; Chlorobenzenes; Columbidae; Cyclohexanes; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Hexachlorocyclohexane; Hydrocarbons, Chlorinated; Liver; Male; Mixed Function Oxygenases; NADP; Oxidoreductases; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1986
Xenobiotic oxidation by cytochrome P-450-enriched extracts of Streptomyces griseus.
    Biochemical and biophysical research communications, 1988, Dec-30, Volume: 157, Issue:3

    Topics: Ammonium Sulfate; Aniline Compounds; Benzene; Benzopyrans; Chemical Phenomena; Chemistry; Coumarins; Cyclohexanes; Cytochrome P-450 Enzyme System; Estradiol; Ferredoxin-NADP Reductase; Ferredoxins; Fractional Precipitation; Kinetics; NADP; Oxidation-Reduction; Pyridines; Streptomyces griseus; Substrate Specificity; Toluene; Xenobiotics

1988
Formation of muconaldehyde, an open-ring metabolite of benzene, in mouse liver microsomes: an additional pathway for toxic metabolites.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:21

    Topics: Aldehydes; Animals; Benzene; Biotransformation; Chromatography, High Pressure Liquid; Male; Mass Spectrometry; Mice; Mice, Inbred Strains; Microsomes, Liver; NADP; Thiobarbiturates

1986
DNA damage in L5178YS cells following exposure to benzene metabolites.
    Molecular pharmacology, 1986, Volume: 30, Issue:1

    Topics: Animals; Benzene; Benzoquinones; Catechols; DNA, Neoplasm; Dose-Response Relationship, Drug; Hydroquinones; Leukemia L5178; Leukemia, Experimental; NADP; Phenol; Phenols; Quinones

1986
Benzene metabolism in mouse liver microsomes.
    Toxicology and applied pharmacology, 1973, Volume: 26, Issue:3

    Topics: Animals; Benzene; Carbon Monoxide; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Hydroxylation; In Vitro Techniques; Kinetics; Male; Mice; Mice, Inbred ICR; Microsomes, Liver; NADP; Oxidoreductases; Phenobarbital; Tritium

1973
Hydroxymethylation of the benzene ring. 1. Microsomal formation of phenol via prior hydroxymethylation of benzene.
    Biochimica et biophysica acta, 1965, Oct-18, Volume: 107, Issue:3

    Topics: Animals; Benzene; Guinea Pigs; In Vitro Techniques; Liver; Microsomes; NADP; Phenols

1965
Hydroxymethylation of the benzene ring. II. Sequential formation of p-hydroxyaniline via hydroxymethylation of aniline by microsomes.
    Biochimica et biophysica acta, 1967, Jun-13, Volume: 141, Issue:1

    Topics: Aminobenzoates; Aniline Compounds; Animals; Benzene; Carbon Isotopes; Guinea Pigs; Hydrogen-Ion Concentration; Hydroxides; Liver; Methylation; Microsomes; NADP; Tritium

1967
Biochemical basis for the in vitro pro-oxidant action of carbon tetrachloride.
    Experimental and molecular pathology, 1969, Volume: 11, Issue:2

    Topics: Aldehydes; Animals; Antimetabolites; Benzene; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochromes; Edetic Acid; Electron Transport; Ferricyanides; Glutathione; Lipid Metabolism; Male; Malonates; Methane; Microsomes, Liver; NADP; Oxidation-Reduction; Rats

1969
Hydroxymethylation of the benzene ring. V. NADPH requirement for aryl hydroxymethylation by a C-1 donor bound to a macromolecule.
    Biochimica et biophysica acta, 1970, Feb-24, Volume: 201, Issue:2

    Topics: Animals; Ascorbic Acid; Benzene; Cell-Free System; Folic Acid; Guinea Pigs; Leucovorin; Microsomes, Liver; NADP; Phenols; Resins, Plant; Serine; Tritium; Vibration

1970
Benzene inhibits RNA synthesis in mitochondria from liver and bone marrow.
    Chemico-biological interactions, 1982, Volume: 42, Issue:3

    Topics: Animals; Benzene; Bone Marrow; Cats; DNA; In Vitro Techniques; Liver Regeneration; Male; Mitochondria; Mitochondria, Liver; NADP; Protein Biosynthesis; Rabbits; Rats; Rats, Inbred Strains; RNA; Toluene

1982
The use of liquid chromatography with dual-electrode electrochemical detection in the investigation of glutathione oxidation during benzene metabolism.
    Journal of chromatography, 1984, Dec-28, Volume: 317

    Topics: Animals; Benzene; Chromatography, Liquid; Electrochemistry; Glutathione; Hydroquinones; In Vitro Techniques; Mice; Microsomes, Liver; NADP; Oxidation-Reduction; Proteins

1984
DT-diaphorase and peroxidase influence the covalent binding of the metabolites of phenol, the major metabolite of benzene.
    Molecular pharmacology, 1984, Volume: 26, Issue:1

    Topics: Animals; Benzene; Guinea Pigs; Kinetics; Male; Microsomes, Liver; NAD; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Peroxidases; Phenol; Phenols; Quinone Reductases

1984
A proposed mechanism of benzene toxicity: formation of reactive intermediates from polyphenol metabolites.
    Toxicology and applied pharmacology, 1981, Jun-30, Volume: 59, Issue:2

    Topics: Animals; Aroclors; Benzene; Biotransformation; Catechols; Chemical Phenomena; Chemistry; Chlorodiphenyl (54% Chlorine); Hydroquinones; Male; NADP; Oxidation-Reduction; Rats; Rats, Inbred F344

1981
Iron-stimulated ring-opening of benzene in a mouse liver microsomal system. Mechanistic studies and formation of a new metabolite.
    Biochemical pharmacology, 1995, Nov-09, Volume: 50, Issue:10

    Topics: Aldehydes; Animals; Antioxidants; Azides; Benzene; Catalase; Copper; Cytochrome P-450 Enzyme System; Edetic Acid; Enzyme Inhibitors; Free Radical Scavengers; Hydroxylation; Iron; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; NADP; Reactive Oxygen Species; Stimulation, Chemical

1995
Cytochrome P450 destruction and radical scavenging by benzene and its metabolites. Evidence for the key role of quinones.
    Biochemical pharmacology, 1994, Jun-15, Volume: 47, Issue:12

    Topics: Animals; Benzene; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Free Radical Scavengers; Male; Microsomes, Liver; NADP; Oxidoreductases; Phenobarbital; Quinones; Rats; Rats, Wistar; Time Factors

1994
Effect of the microsomal system on quinone redox cycling, oxygen activation, and lipid peroxidation.
    Advances in experimental medicine and biology, 2001, Volume: 500

    Topics: Animals; Benzene; Benzoquinones; Cytochrome P-450 CYP2E1; Hydroquinones; Lipid Peroxidation; Microsomes; NADP; Oxidation-Reduction; Oxygen; Rats

2001
ENZYMATIC FORMATION OF CATECHOL FROM ANTHRANILIC ACID.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Benzene; Benzoates; Carbon Isotopes; Catechols; Glycols; Kynurenic Acid; Levulinic Acids; Metabolism; Mixed Function Oxygenases; NAD; NADP; ortho-Aminobenzoates; Oxidoreductases; Pseudomonas; Research; Salicylic Acid; Tryptophan

1964
Cytochrome P450 destruction by benzene metabolites 1,4-benzoquinone and 1,4-hydroquinone and the formation of hydroxyl radicals in minipig liver microsomes.
    Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:4

    Topics: Algorithms; Animals; Antimetabolites, Antineoplastic; Benzene; Benzoquinones; Catechols; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Doxorubicin; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Hydroquinones; Hydroxyl Radical; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Orchiectomy; Oxidative Stress; Structure-Activity Relationship; Swine; Swine, Miniature

2007
Combined structural and functional investigation of a C-3''-ketoreductase involved in the biosynthesis of dTDP-L-digitoxose.
    Biochemistry, 2011, Jul-05, Volume: 50, Issue:26

    Topics: Actinomycetales; Alcohol Oxidoreductases; Benzene; Binding Sites; Hexoses; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NADP; Nucleoside Diphosphate Sugars; Protein Conformation

2011
Chemically engineered papain as artificial formate dehydrogenase for NAD(P)H regeneration.
    Organic & biomolecular chemistry, 2011, Aug-21, Volume: 9, Issue:16

    Topics: 2,2'-Dipyridyl; Benzene; Cymenes; Ethylenediamines; Formate Dehydrogenases; Monoterpenes; NADP; Organometallic Compounds; Oxidation-Reduction; Papain; Phenanthrolines; Ruthenium

2011
Genome-wide functional profiling reveals genes required for tolerance to benzene metabolites in yeast.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Animals; Benzene; Cell Nucleus; Cluster Analysis; Cytoskeleton; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Fungal Proteins; Genes, Fungal; Genomics; Homeostasis; Humans; Iron; Membrane Lipids; Molecular Sequence Data; NAD(P)H Dehydrogenase (Quinone); NADP; Phenols; Saccharomyces cerevisiae; Species Specificity; Time Factors; Vacuolar Proton-Translocating ATPases; Vacuoles

2011
Highly selective hydroxylation of benzene to phenol by wild-type cytochrome P450BM3 assisted by decoy molecules.
    Angewandte Chemie (International ed. in English), 2013, Jun-24, Volume: 52, Issue:26

    Topics: Alkanes; Animals; Benzene; Catalytic Domain; Cytochrome P-450 Enzyme System; Drug Design; Enzymes; Fatty Acids, Monounsaturated; Fluorocarbons; Humans; Hydroxylation; Mutagenesis; NADP; Phenol; Rats

2013
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