benzbromarone and probenecid

benzbromarone has been researched along with probenecid in 68 studies

Research

Studies (68)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (23.53)	18.7374
1990's	17 (25.00)	18.2507
2000's	13 (19.12)	29.6817
2010's	19 (27.94)	24.3611
2020's	3 (4.41)	2.80

Authors

Authors	Studies
Bröer, A; Bröer, S; Deitmer, JW; Halestrap, AP; Schneider, HP; Stegen, C	1
Beijnen, JH; Borst, P; Reid, G; Saeki, T; Zelcer, N	1
Boyd, CD; Iliás, A; Le Saux, O; Sarkadi, B; Seidl, TL; Sinkó, E; Urbán, Z; Váradi, A	1
Endou, H; Hosoya, T; Hosoyamada, M; Ichida, K; Kimura, H; Takeda, M; Utsunomiya, Y	1
Cheng, CH; Fong, WP; Yu, Z	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Anzai, N; Endou, H; Frick, MM; Iwen, TJ; Jutabha, P; Quade, B; Rice, PJ; Ross, IR; Wempe, MF	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Fu, P; Li, X; Liu, J; Ma, L	1
Fanelli, GM	1
Kleinschmidt, A; Schräpler, P; Schulz, E	1
Haese, E; Kleinschmidt, A; Schräpler, P	1
Yu, TF	1
Inagaki, H; Nakai, T; Shinosaki, T; Yamashita, T; Yonetani, Y	1
Higashino, K; Moriwaki, Y; Suda, M; Takahashi, S; Yamamoto, T	1
Hada, T; Higashino, K; Moriwaki, Y; Takahashi, S; Yamamoto, T	3
Cabo, J; Gómez-Ruiz, MD; Izquierdo, R; Rodilla, F; Sánchez-Beltrán, MJ	3
Goto, H; Ito, A; Mikami, T	1
Brasch, H; Iven, H	1
Schoeman, HS; Sommers, DK	1
Homma, Y; Kitamura, T; Nishimura, Y	1
Rodnan, GP	1
Schepers, GW	1
Akaoka, I; Fujimori, S; Kaneko, K; Yamanaka, H	1
Hiroshige, K; Kuroiwa, A; Takasugi, M; Yuu, K	1
Kawai, S; Osawa, G; Yamada, M	1
Fujimoto, Y; Hirata, N; Hisatome, I; Kosaka, H; Kotake, H; Mashiba, H; Sato, R; Shigemasa, C; Tanaka, Y; Yoshida, A	1
Fujimoto, Y; Hisatome, I; Igawa, O; Kosaka, H; Manabe, I; Ohtahara, A; Ohtahara, K; Sawaguchi, M; Shigemasa, C; Takeda, A; Tanaka, Y; Tsuboi, M; Yoshida, A	1
Diezi, J; Guisan, B; Roch-Ramel, F	1
Berger, W; Elbling, L; Hauptmann, E; Kokoschka, EM; Micksche, M; Vetterlein, M	1
Goriki, K; Ochiai, M; Okusaki, K; Takahashi, H; Toda, K; Tokunou, H; Uehara, S	1
Hirai, A; Saito, Y	1
Hamada, N; Hiroe, K; Hisatome, I; Kato, T; Kinugawa, T; Manabe, I; Ogino, K; Ohtahara, A; Sato, R; Shigemasa, C; Shimoyama, M; Takeda, A; Tanaka, Y; Tsuboi, M; Yamamoto, Y; Yoshida, A	1
Fend, F; Gruber, J; König, P; Lhotta, K; Sgonc, R	1
Bergmann, R; Center, MS; Couraud, PO; El Hafny, B; Koman, A; Piciotti, M; Regina, A; Roux, F	1
Decaux, G; Hannotier, P; Musch, W; Prospert, F; Soupart, A	1
Chazerain, P; Ziza, JM	1
Beijnen, J; Borst, P; de Haas, M; Evers, R; Lankelma, J; Sparidans, R; Wielinga, PR	1
Gröbner, W; Walter-Sack, I	1
Yamanaka, H	1
Hosoyamada, M; Ichida, K	1
Hosoyamada, M; Ichida, K; Shibasaki, T	1
Brouwers, JR; Houtman, PM; Jansen, TL; Reinders, MK; van Roon, EN	1
Caci, E; Diena, T; Galietta, LJ; Melani, R; Pedemonte, N; Sondo, E; Zegarra-Moran, O	1
Brouwers, JR; Delsing, J; Griep, EN; Hoekstra, M; Jansen, TL; Reinders, MK; van de Laar, MA; van Roon, EN	1
Hisatome, I	1
Taniguchi, A	1
Anzai, N; Endou, H; Enomoto, A; Fujimura, M; Miyazaki, H; Shin, HJ; Takeda, M	1
Kriegsmann, J; Lange, U; Müller-Ladner, U; Panzner, I; Tausche, AK	1
Bombardier, C; Buchbinder, R; Edwards, CJ; Kydd, AS; Seth, R	2
Dalbeth, N; Robinson, PC	1
Stamp, LK	1
Jansen, TL; Perez-Ruiz, F; Richette, P; Tausche, AK	1
Deng, X; Li, J; Liu, H; Qi, Y; Xiong, B; Zhang, Y	1
Cao, Y; Chen, Y; Jiang, Y; Li, L; Li, Y; Pang, J; Wu, T; Zhao, Z; Zhou, P	1
Borghi, C; Cicero, AFG; Fogacci, F; Kuwabara, M	1
Ashizawa, N; Chikamatsu, N; Iwanaga, T; Motoki, K; Sakai, M; Taniguchi, T; Yamano, K	1

Reviews

17 review(s) available for benzbromarone and probenecid

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Pharmacological urate-lowering approaches in chronic kidney disease. European journal of medicinal chemistry, 2019, Mar-15, Volume: 166 Topics: Biological Products; Drug Discovery; Flavonoids; Humans; Renal Insufficiency, Chronic; Uric Acid	2019
Urate excretion. Annual review of medicine, 1977, Volume: 28 Topics: Acetohexamide; Animals; Benzbromarone; Benzofurans; Diuretics; Ethambutol; Halofenate; Humans; Mersalyl; Pan troglodytes; Probenecid; Salicylates; Sulfinpyrazone; Uric Acid; Zoxazolamine	1977
Treatment of the gout and other forms of crystal-induced arthritis. Bulletin on the rheumatic diseases, 1982, Volume: 32, Issue:5 Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Benzbromarone; Colchicine; Gout; Gout Suppressants; Humans; Indomethacin; Kidney; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric Acid	1982
[Management of hyperuricemia in diabetes]. Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55 Suppl Topics: Allopurinol; Benzbromarone; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Humans; Insulin Resistance; Probenecid; Uric Acid; Uricosuric Agents	1997
[Drug therapy for idiopathic hyperuricemia--introduction, dose, and side effects]. Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 1 Topics: Allopurinol; Arteriosclerosis; Benzbromarone; Enzyme Inhibitors; Gout; Humans; Hyperuricemia; Kidney Diseases; Probenecid; Prognosis; Risk; Uricosuric Agents; Urinary Calculi; Xanthine Oxidase	2003
[Molecular mechanism for urinary excretion of hypoxanthine and xanthine]. Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 1 Topics: Animals; Benzbromarone; Biological Transport; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Kidney; Membrane Transport Proteins; Probenecid; Pyrazinamide; Uricosuric Agents; Xanthine	2003
[Molecular mechanism in biological transport in the kidney: Urate transporter URAT1]. Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 2 Topics: Animals; Benzbromarone; Carrier Proteins; Humans; Hyperuricemia; Kidney Tubules; Organic Anion Transporters; Organic Cation Transport Proteins; Probenecid; RNA, Messenger; Transcription, Genetic; Uric Acid; Uricosuric Agents	2006
[Impact of serum uric acid level on the cardiovascular system as a risk factor]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2010, Volume: 136, Issue:6 Topics: Adipokines; Benzbromarone; Cardiovascular Diseases; Hyperuricemia; Kidney; Organic Anion Transporters; Organic Cation Transport Proteins; Oxidation-Reduction; Probenecid; Renal Tubular Transport, Inborn Errors; Risk Factors; Uric Acid; Uricosuric Agents; Urinary Calculi	2010
[Treatment of hyperuricemia and gout based on the guideline for the management of hyperuricemia and gout]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2010, Volume: 136, Issue:6 Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Colchicine; Glucocorticoids; Gout; Gout Suppressants; Humans; Hyperuricemia; Life Style; Metabolic Syndrome; Practice Guidelines as Topic; Probenecid; Uricosuric Agents	2010
[Gout - regardless of therapeutic options a "forgotten" disease]. Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:33 Topics: Allopurinol; Arthritis, Gouty; Benzbromarone; Combined Modality Therapy; Cytokines; Europe; Febuxostat; Gout; Gout Suppressants; Guideline Adherence; Humans; Inflammasomes; Interleukin-1; Long-Term Care; Probenecid; Signal Transduction; Thiazoles; Uric Acid	2011
Allopurinol for chronic gout. The Cochrane database of systematic reviews, 2014, Oct-14, Issue:10 Topics: Allopurinol; Benzbromarone; Chronic Disease; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Probenecid; Randomized Controlled Trials as Topic; Thiazoles; Uric Acid	2014
Uricosuric medications for chronic gout. The Cochrane database of systematic reviews, 2014, Nov-14, Issue:11 Topics: Adult; Aged; Allopurinol; Benzbromarone; Chronic Disease; Controlled Clinical Trials as Topic; Female; Gout; Humans; Male; Middle Aged; Probenecid; Randomized Controlled Trials as Topic; Uric Acid; Uricosuric Agents	2014
Advances in pharmacotherapy for the treatment of gout. Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:4 Topics: Adrenal Cortex Hormones; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzbromarone; Clinical Trials, Phase III as Topic; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Polyethylene Glycols; Probenecid; Thiazoles; Urate Oxidase; Uric Acid	2015
Major unanswered questions in the clinical gout field. Current opinion in rheumatology, 2017, Volume: 29, Issue:2 Topics: Allopurinol; Benzbromarone; Colchicine; Disease Progression; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Patient Care Planning; Probenecid; Renal Insufficiency, Chronic; Uric Acid; Uricosuric Agents	2017
International position paper on the appropriate use of uricosurics with the introduction of lesinurad. Clinical rheumatology, 2018, Volume: 37, Issue:12 Topics: Benzbromarone; Europe; Febuxostat; Gout; Humans; International Cooperation; Practice Guidelines as Topic; Probenecid; Rheumatology; Thioglycolates; Triazoles; Uricosuric Agents; Xanthine Oxidase	2018
Therapeutic Strategies for the Treatment of Chronic Hyperuricemia: An Evidence-Based Update. Medicina (Kaunas, Lithuania), 2021, Jan-10, Volume: 57, Issue:1 Topics: Acetamides; Allopurinol; Benzbromarone; Chronic Disease; Evidence-Based Medicine; Febuxostat; Gout Suppressants; Humans; Hyperuricemia; Naphthalenes; Nitriles; Phenylacetates; Polyethylene Glycols; Probenecid; Propionates; Pyridines; Thioglycolates; Triazoles; Urate Oxidase; Uricosuric Agents; Xanthine Oxidase	2021

Trials

7 trial(s) available for benzbromarone and probenecid

Article	Year
[The uricosuric effect of benzbromaron and probenecid under fasting conditions (author's transl)]. Medizinische Klinik, 1978, Feb-17, Volume: 73, Issue:7 Topics: Benzbromarone; Benzofurans; Dose-Response Relationship, Drug; Fasting; Female; Humans; Kidney Tubules; Male; p-Aminohippuric Acid; Probenecid; Uric Acid	1978
[The effect of benzbromarone on fasting-hyperuricemia as a model (author's transl)]. Medizinische Klinik, 1978, Jun-09, Volume: 73, Issue:23 Topics: Adolescent; Adult; Benzbromarone; Benzofurans; Fasting; Female; Humans; Male; Middle Aged; Obesity; Probenecid; Purines; Uric Acid	1978
Effects of pyrazinamide, probenecid, and benzbromarone on renal excretion of oxypurinol. Annals of the rheumatic diseases, 1991, Volume: 50, Issue:9 Topics: Adult; Benzbromarone; Biological Transport; Humans; Kidney; Male; Oxypurinol; Probenecid; Pyrazinamide	1991
Benzbromarone therapy in hyperuricaemia; comparison with allopurinol and probenecid. The Journal of international medical research, 1981, Volume: 9, Issue:6 Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Clinical Trials as Topic; Female; Humans; Male; Placebos; Probenecid; Uric Acid	1981
Effect of hypouricemic agents on serum carbohydrate-deficient transferrin in gouty patients. Advances in experimental medicine and biology, 1994, Volume: 370 Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Allopurinol; Benzbromarone; Chromatography, Ion Exchange; Drug Therapy, Combination; Gout; Humans; Isoelectric Focusing; Male; Middle Aged; Oxypurinol; Probenecid; Radioimmunoassay; Transferrin	1994
Biochemical effectiveness of allopurinol and allopurinol-probenecid in previously benzbromarone-treated gout patients. Clinical rheumatology, 2007, Volume: 26, Issue:9 Topics: Allopurinol; Benzbromarone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gout; Humans; Hyperuricemia; Male; Middle Aged; Probenecid; Uric Acid; Uricosuric Agents	2007
Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinol. Annals of the rheumatic diseases, 2009, Volume: 68, Issue:1 Topics: Aged; Allopurinol; Benzbromarone; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Hypersensitivity; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Probenecid; Prospective Studies; Treatment Failure; Uric Acid	2009

Other Studies

44 other study(ies) available for benzbromarone and probenecid

Article	Year
Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes. The Biochemical journal, 1999, Aug-01, Volume: 341 ( Pt 3) Topics: Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA Primers; Female; Hydrogen-Ion Concentration; Lactic Acid; Monocarboxylic Acid Transporters; Oocytes; Rats; Substrate Specificity; Xenopus laevis	1999
Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3). The Journal of biological chemistry, 2001, Dec-07, Volume: 276, Issue:49 Topics: Animals; Biological Transport; Cell Line; Chromatography, High Pressure Liquid; Cloning, Molecular; DNA, Complementary; Drug Resistance, Multiple; Etoposide; Glutathione; Humans; Mice; Multidrug Resistance-Associated Proteins; Transfection	2001
Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6). The Journal of biological chemistry, 2002, May-10, Volume: 277, Issue:19 Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Biological Transport; Blotting, Western; Cell Line; Cell Membrane; DNA, Complementary; Dose-Response Relationship, Drug; Gene Library; Glutathione; Humans; Insecta; Kinetics; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Mutation; Mutation, Missense; Nucleotides; Protein Binding; Protein Biosynthesis; Pseudoxanthoma Elasticum; Time Factors; Transcription, Genetic	2002
Urate transport via human PAH transporter hOAT1 and its gene structure. Kidney international, 2003, Volume: 63, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Biological Transport; Blotting, Western; Carbon Radioisotopes; Cell Line; Cloning, Molecular; Exons; Female; Gene Library; Gout; Humans; Kidney; Kidney Diseases; Organic Anion Transport Protein 1; p-Aminohippuric Acid; Probenecid; Protein Structure, Tertiary; Pyrazinamide; Sodium Salicylate; Uric Acid; Uricosuric Agents	2003
Morin (3,5,7,2',4'-pentahydroxyflavone) exhibits potent inhibitory actions on urate transport by the human urate anion transporter (hURAT1) expressed in human embryonic kidney cells. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:6 Topics: Benzbromarone; Cell Line; Flavonoids; Humans; Kidney; Organic Anion Transporters; Organic Cation Transport Proteins; Probenecid; Sulfinpyrazone; Transfection; Uric Acid; Uricosuric Agents	2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Developing potent human uric acid transporter 1 (hURAT1) inhibitors. Journal of medicinal chemistry, 2011, Apr-28, Volume: 54, Issue:8 Topics: Animals; Drug Design; Humans; Kidney; Magnetic Resonance Spectroscopy; Organic Anion Transporters; Organic Cation Transport Proteins; Xenopus	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone. The Journal of rheumatology, 1976, Volume: 3, Issue:3 Topics: Adult; Aged; Arthritis; Benzbromarone; Benzofurans; Chemical Phenomena; Chemistry; Chronic Disease; Gout; Humans; Hydrochlorothiazide; Kinetics; Middle Aged; Probenecid; Sulfinpyrazone; Uric Acid	1976
Circadian rhythm of plasma uric acid and handling stress-induced hyperuricemia in conscious cebus monkeys. Japanese journal of pharmacology, 1992, Volume: 58, Issue:4 Topics: Animals; Benzbromarone; Cebus; Circadian Rhythm; Diazepam; Female; Gum Arabic; Handling, Psychological; Male; Probenecid; Stress, Physiological; Uric Acid	1992
Renal excretions of oxypurinol and oxypurines--effects of pyrazinamide, probenecid and benzbromarone. Advances in experimental medicine and biology, 1989, Volume: 253A Topics: Adult; Benzbromarone; Gout Suppressants; Humans; Kidney; Male; Metabolic Clearance Rate; Oxypurinol; Probenecid; Pyrazinamide; Pyrimidines	1989
Renal excretion of purine bases--effects of probenecid, benzbromarone and pyrazinamide. Advances in experimental medicine and biology, 1989, Volume: 253A Topics: Adult; Benzbromarone; Gout Suppressants; Humans; Kidney; Male; Metabolic Clearance Rate; Probenecid; Purines; Pyrazinamide	1989
Effect of probenecid and benzbromarone on gluconeogenesis in isolated rat liver cells. Revista espanola de fisiologia, 1989, Volume: 45, Issue:4 Topics: Animals; Benzbromarone; Benzofurans; Cells, Cultured; Depression, Chemical; Gluconeogenesis; Liver; Male; NAD; Probenecid; Rats; Rats, Inbred Strains; Uricosuric Agents	1989
[Effect of exercise on urate excretion]. Nihon seirigaku zasshi. Journal of the Physiological Society of Japan, 1989, Volume: 51, Issue:7 Topics: Adult; Benzbromarone; Depression, Chemical; Exercise; Glomerular Filtration Rate; Humans; Kidney; Male; Probenecid; Pyrazinamide; Uric Acid	1989
Inhibition of purine catabolism by benzbromarone in isolated rat liver cells. Comparison with allopurinol and probenecid. Biochemical pharmacology, 1988, Oct-01, Volume: 37, Issue:19 Topics: Allopurinol; Animals; Benzbromarone; Benzofurans; In Vitro Techniques; Liver; Male; Probenecid; Purines; Rats; Rats, Inbred Strains; Uric Acid	1988
Inhibition of ureogenesis by two hypouricemic drugs (probenecid and benzbromarone). Comparison with allopurinol. Cellular and molecular biology, 1988, Volume: 34, Issue:6 Topics: Allopurinol; Animals; Arginine; Benzbromarone; In Vitro Techniques; Liver; Male; Probenecid; Rats; Rats, Inbred Strains; Urea; Uricosuric Agents	1988
Renal excretion of purine bases. Effects of probenecid, benzbromarone and pyrazinamide. Nephron, 1988, Volume: 48, Issue:2 Topics: Adult; Benzbromarone; Benzofurans; Biological Transport, Active; Female; Humans; Hypoxanthine; Hypoxanthines; Kidney; Male; Probenecid; Purines; Pyrazinamide; Uric Acid; Xanthine; Xanthines	1988
The effects of antibiotics and uricosuric drugs on the renal elimination of methotrexate and 7-hydroxymethotrexate in rabbits. Cancer chemotherapy and pharmacology, 1988, Volume: 21, Issue:4 Topics: Animals; Anti-Bacterial Agents; Benzbromarone; Ceftriaxone; Furosemide; Kidney; Metabolic Clearance Rate; Methotrexate; Piperacillin; Probenecid; Rabbits; Sulfamethoxazole; Sulfinpyrazone; Uricosuric Agents	1988
Drug interactions with urate excretion in man. European journal of clinical pharmacology, 1987, Volume: 32, Issue:5 Topics: Adult; Ampicillin; Benzbromarone; Benzofurans; Drug Interactions; Humans; Kidney; Kinetics; Male; Probenecid; Pyrazinamide; Uric Acid	1987
[A case of familial renal hypouricemia associated with bladder cancer]. Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1984, Volume: 75, Issue:2 Topics: Aged; Benzbromarone; Carcinoma, Transitional Cell; Humans; Male; Probenecid; Pyrazinamide; Renal Tubular Transport, Inborn Errors; Uric Acid; Urinary Bladder Neoplasms	1984
Pharmacologic evaluation of the renal handling of uric acid and oxypurines. Nihon Jinzo Gakkai shi, 1994, Volume: 36, Issue:11 Topics: Adult; Benzbromarone; Biological Transport; Humans; Hypoxanthine; Hypoxanthines; Kidney Tubules; Male; Probenecid; Pyrazinamide; Uric Acid; Xanthines	1994
Renal hypouricemia: incomplete combined defect. Nihon Jinzo Gakkai shi, 1994, Volume: 36, Issue:8 Topics: Adult; Benzbromarone; Calcium; Humans; Male; Nephrosis, Lipoid; Probenecid; Pyrazinamide; Uric Acid	1994
Renal hypouricemia due to enhanced tubular secretion of urate associated with urolithiasis: successful treatment of urolithiasis by alkalization of urine K+, Na(+)-citrate. Nephron, 1993, Volume: 65, Issue:4 Topics: Benzbromarone; Citrates; Creatinine; Female; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Kidney Tubules; Middle Aged; Probenecid; Pyrazinamide; Uric Acid; Urinary Calculi	1993
Renal handling of urate in a patient with familial juvenile gouty nephropathy. Internal medicine (Tokyo, Japan), 1996, Volume: 35, Issue:7 Topics: Adolescent; Benzbromarone; Female; Genes, Dominant; Gout; Gout Suppressants; Humans; Kidney; Kidney Failure, Chronic; Male; Pedigree; Probenecid; Pyrazinamide; Renal Agents; Uric Acid; Uricosuric Agents	1996
Effects of uricosuric and antiuricosuric agents on urate transport in human brush-border membrane vesicles. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2 Topics: Aged; Benzbromarone; Biological Transport; Biphenyl Compounds; Carbon Radioisotopes; Diuretics; Ethambutol; Humans; Imidazoles; Kidney Cortex; Kidney Neoplasms; Kinetics; Losartan; Microvilli; Middle Aged; Probenecid; Pyrazinamide; Salicylates; Salicylic Acid; Sulfinpyrazone; Tetrazoles; Ticrynafen; Uric Acid; Uricosuric Agents	1997
Possible role of the multidrug resistance-associated protein (MRP) in chemoresistance of human melanoma cells. International journal of cancer, 1997, Mar-28, Volume: 71, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents; ATP-Binding Cassette Transporters; Benzbromarone; Blotting, Northern; Cisplatin; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Ethylmaleimide; Etoposide; Female; Fluoresceins; Humans; Male; Melanoma; Middle Aged; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Probenecid; RNA, Messenger; Tumor Cells, Cultured; Uricosuric Agents; Vinblastine	1997
Gout due to xanthine derivatives. British journal of rheumatology, 1997, Volume: 36, Issue:10 Topics: Allopurinol; Aminophylline; Asthma; Benzbromarone; Bronchodilator Agents; Drug Therapy, Combination; Female; Gout; Humans; Middle Aged; Probenecid; Theophylline; Uric Acid; Uricosuric Agents	1997
Hematuria in patients with renal hypouricemia. Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Benzbromarone; Creatinine; Female; Hematuria; Humans; Kidney Diseases; Male; Metabolism, Inborn Errors; Middle Aged; Probenecid; Pyrazinamide; Renal Agents; Uric Acid	1998
Apoptosis of tubular epithelial cells in familial juvenile gouty nephropathy. Nephron, 1998, Volume: 79, Issue:3 Topics: Adult; Apoptosis; Benzbromarone; Biopsy; Biotin; Deoxyuracil Nucleotides; DNA Fragmentation; Family Health; Female; Genes, Dominant; Glomerulosclerosis, Focal Segmental; Gout; Humans; Kidney Failure, Chronic; Kidney Tubules, Proximal; Male; Middle Aged; Pedigree; Probenecid; Staining and Labeling; Uremia; Uric Acid; Uricosuric Agents	1998
Mrp1 multidrug resistance-associated protein and P-glycoprotein expression in rat brain microvessel endothelial cells. Journal of neurochemistry, 1998, Volume: 71, Issue:2 Topics: Animals; Antineoplastic Agents, Phytogenic; Astrocytes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzbromarone; Brain; Capillaries; Carcinogens; Cell Line, Transformed; Colchicine; Cyclosporine; DNA-Binding Proteins; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genistein; Gout Suppressants; Immunoblotting; Multidrug Resistance-Associated Proteins; MutS Homolog 3 Protein; Polymerase Chain Reaction; Probenecid; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfinpyrazone; Uricosuric Agents; Vinblastine; Vincristine	1998
Restoration of the uricosuric effect of probenecid after triglycylvasopressine administration in a gouty patient. Clinical nephrology, 1998, Volume: 50, Issue:4 Topics: Absorption; Acute Kidney Injury; Adult; Anti-Inflammatory Agents; Benzbromarone; Fludrocortisone; Gout; Humans; Kidney Tubules; Lypressin; Male; Probenecid; Pyrazinamide; Receptors, Vasopressin; Renal Agents; Terlipressin; Uric Acid; Uricosuric Agents	1998
[Gout: physiopathology, diagnosis, course, treatment]. La Revue du praticien, 1998, Sep-01, Volume: 48, Issue:13 Topics: Adult; Aged; Allopurinol; Arthritis, Gouty; Benzbromarone; Diagnosis, Differential; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Probenecid; Synovial Fluid; Uric Acid; Uricosuric Agents	1998
Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export. British journal of cancer, 2000, Volume: 83, Issue:3 Topics: Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Benzbromarone; Biological Transport, Active; Carrier Proteins; Dose-Response Relationship, Drug; Glutathione; Humans; Indomethacin; Probenecid; Sulfinpyrazone; Tumor Cells, Cultured; Uricosuric Agents; Vinblastine	2000
[Hyperuricemia and gout--treatment]. Deutsche medizinische Wochenschrift (1946), 2002, Feb-01, Volume: 127, Issue:5 Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Colchicine; Drug Therapy, Combination; Glucocorticoids; Gout; Gout Suppressants; Humans; Kidney Calculi; Kidney Diseases; Probenecid; Time Factors; Uric Acid; Uricosuric Agents	2002
Block of CFTR-dependent chloride currents by inhibitors of multidrug resistance-associated proteins. European journal of pharmacology, 2007, Apr-10, Volume: 560, Issue:2-3 Topics: Animals; ATP-Binding Cassette Transporters; Benzbromarone; Cells, Cultured; Chloride Channels; Cystic Fibrosis Transmembrane Conductance Regulator; Probenecid; Rats; Rats, Inbred F344; Sulfinpyrazone	2007
Interactions of urate transporter URAT1 in human kidney with uricosuric drugs. Nephrology (Carlton, Vic.), 2011, Volume: 16, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Benzothiazoles; Biological Transport; Captopril; Cells, Cultured; Dogs; Enalapril; Indomethacin; Inhibitory Concentration 50; Organic Anion Transporters; Organic Cation Transport Proteins; Phenylbutazone; Probenecid; Pyridines; Salicylates; Sulfinpyrazone; Uric Acid; Uricosuric Agents	2011
[Simultaneous determination of allopurinol, probenecid, benzbromarone in dietary supplements by ultra high performance liquid chromatography-tandem mass spectrometry]. Se pu = Chinese journal of chromatography, 2019, Feb-08, Volume: 37, Issue:2 Topics: Allopurinol; Benzbromarone; Chromatography, High Pressure Liquid; Dietary Supplements; Probenecid; Tandem Mass Spectrometry	2019
Characterizations of the Urate Transporter, GLUT9, and Its Potent Inhibitors by Patch-Clamp Technique. SLAS discovery : advancing life sciences R & D, 2021, Volume: 26, Issue:3 Topics: Animals; Benzbromarone; Biological Transport; Gene Expression; Glucose Transport Proteins, Facilitative; Gout Suppressants; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Mice; Naphthalenes; Patch-Clamp Techniques; Plasmids; Potassium; Probenecid; Propionates; Pyridines; Transgenes; Uric Acid	2021
Uricosuric Agents Affect Plasma and Kidney Concentration of Adefovir via Inhibition of Oat1 and Mrp2 in Rats. Biological & pharmaceutical bulletin, 2023, Volume: 46, Issue:2 Topics: Animals; Benzbromarone; Kidney; Organic Anion Transporters; Probenecid; Rats; Rats, Sprague-Dawley; Uric Acid; Uricosuric Agents	2023