benzbromarone and oxypurinol

benzbromarone has been researched along with oxypurinol in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19907 (46.67)18.7374
1990's4 (26.67)18.2507
2000's3 (20.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Klein, G; Rainer, F; Wottawa, A1
Bargnoux, H; Berger, JA; Bussiere, JL; Chabard, JL; Lartigue-Mattei, C; Petit, J; Ristori, JM1
Higashino, K; Moriwaki, Y; Suda, M; Takahashi, S; Yamamoto, T1
Hada, T; Higashino, K; Moriwaki, Y; Takahashi, S; Yamamoto, T1
Clavel, JP; Colin, JN; Dietlin, F; Farinotti, R; Fredj, G; Tod, M; Vignon, E1
Eichhorn, R; Mertz, DP1
Borner, K; Mertz, DP1
Henkel, E; Mitzkat, HJ; Rüffer, C; Zorn, G1
Breithaupt, B; Tittel, M1
Akaoka, I; Fujimori, S; Kaneko, K; Yamanaka, H1
Groenewoud, G; Hundt, HK; Müller, FO; Schall, R; van der Merwe, JC; van Dyk, M1
Hirayama, M; Iwanaga, T; Kobayashi, D; Maeda, T; Tamai, I1
Gomi, H; Hikita, M; Hosoya, T; Ichida, K; Ohno, I; Okabe, H; Saikawa, H; Uetake, D; Yamaguchi, Y1
Brouwers, JR; Delsing, J; Haagsma, C; Jansen, TL; Reinders, MK; van de Laar, MA; van Roon, EN1

Trials

5 trial(s) available for benzbromarone and oxypurinol

ArticleYear
Effects of pyrazinamide, probenecid, and benzbromarone on renal excretion of oxypurinol.
    Annals of the rheumatic diseases, 1991, Volume: 50, Issue:9

    Topics: Adult; Benzbromarone; Biological Transport; Humans; Kidney; Male; Oxypurinol; Probenecid; Pyrazinamide

1991
[Excretion and serum concentrations of allopurinol, oxipurinol and oxipurines in combined treatment with allopurinol and benzbromarone in increasing doses].
    Die Medizinische Welt, 1983, Sep-09, Volume: 34, Issue:36

    Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gout; Humans; Male; Metabolic Clearance Rate; Middle Aged; Oxypurinol; Purines; Pyrimidines

1983
Effect of hypouricemic agents on serum carbohydrate-deficient transferrin in gouty patients.
    Advances in experimental medicine and biology, 1994, Volume: 370

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Allopurinol; Benzbromarone; Chromatography, Ion Exchange; Drug Therapy, Combination; Gout; Humans; Isoelectric Focusing; Male; Middle Aged; Oxypurinol; Probenecid; Radioimmunoassay; Transferrin

1994
The effect of benzbromarone on allopurinol/oxypurinol kinetics in patients with gout.
    European journal of clinical pharmacology, 1993, Volume: 44, Issue:1

    Topics: Adult; Aged; Allopurinol; Benzbromarone; Gout; Humans; Male; Middle Aged; Oxypurinol; Uric Acid

1993
A randomised controlled trial on the efficacy and tolerability with dose escalation of allopurinol 300-600 mg/day versus benzbromarone 100-200 mg/day in patients with gout.
    Annals of the rheumatic diseases, 2009, Volume: 68, Issue:6

    Topics: Aged; Allopurinol; Benzbromarone; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Oxypurinol; Patient Compliance; Prospective Studies; Treatment Outcome; Uric Acid; Uricosuric Agents

2009

Other Studies

10 other study(ies) available for benzbromarone and oxypurinol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[The effect of uricosuric and uricostatic drugs on DNA metabolism].
    Acta medica Austriaca, 1976, Volume: 3, Issue:3

    Topics: Allopurinol; Benzbromarone; Cells, Cultured; DNA; Gout Suppressants; Oxypurinol; Radiation, Ionizing; Thymidine; Ultraviolet Rays; Uricosuric Agents

1976
Kinetics of allopurinol and its metabolite oxypurinol after oral administration of allopurinol alone or associated with benzbromarone in man. Simultaneous assay of hypoxanthine and xanthine by gas chromatography-mass spectrometry.
    Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:7

    Topics: Adult; Allopurinol; Benzbromarone; Drug Combinations; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Hypoxanthines; Male; Models, Biological; Oxypurinol; Xanthines

1991
Renal excretions of oxypurinol and oxypurines--effects of pyrazinamide, probenecid and benzbromarone.
    Advances in experimental medicine and biology, 1989, Volume: 253A

    Topics: Adult; Benzbromarone; Gout Suppressants; Humans; Kidney; Male; Metabolic Clearance Rate; Oxypurinol; Probenecid; Pyrazinamide; Pyrimidines

1989
Kinetics of allopurinol and oxipurinol after chronic oral administration. Interaction with benzbromarone.
    European journal of clinical pharmacology, 1986, Volume: 31, Issue:1

    Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Creatinine; Drug Interactions; Female; Half-Life; Humans; Kinetics; Male; Oxypurinol; Pyrimidines; Uric Acid

1986
Does benzbromarone in therapeutic doses raise renal excretion of oxipurinol?
    Klinische Wochenschrift, 1984, Dec-17, Volume: 62, Issue:24

    Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Creatinine; Drug Therapy, Combination; Glomerular Filtration Rate; Gout; Humans; Male; Middle Aged; Oxypurinol; Pyrimidines; Uric Acid

1984
[Influence of benzbromarone on the pharmacokinetics and pharmacodynamics of oxipurinol].
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:9

    Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Drug Combinations; Glomerular Filtration Rate; Humans; Kinetics; Male; Oxypurinol; Pyrimidines

1982
Kinetics of allopurinol after single intravenous and oral doses. Noninteraction with benzbromarone and hydrochlorothiazide.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:1

    Topics: Administration, Oral; Adult; Allopurinol; Benzbromarone; Benzofurans; Biological Availability; Drug Interactions; Female; Humans; Hydrochlorothiazide; Injections, Intravenous; Kinetics; Male; Oxypurinol; Time Factors

1982
Involvement of uric acid transporter in increased renal clearance of the xanthine oxidase inhibitor oxypurinol induced by a uricosuric agent, benzbromarone.
    Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:12

    Topics: Animals; Benzbromarone; Carrier Proteins; Drug Interactions; Enzyme Inhibitors; Humans; Kidney; Metabolic Clearance Rate; Organic Anion Transporters; Organic Cation Transport Proteins; Oxypurinol; Solute Carrier Family 22 Member 5; Symporters; Uric Acid; Uricosuric Agents; Xenopus laevis

2005
[Usefulness of combination treatment using allopurinol and benzbromarone for gout and hyperuricemia accompanying renal dysfunction: kinetic analysis of oxypurinol].
    Nihon Jinzo Gakkai shi, 2008, Volume: 50, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Benzbromarone; Drug Therapy, Combination; Gout; Gout Suppressants; Humans; Hyperuricemia; Kidney Diseases; Male; Middle Aged; Oxypurinol; Retrospective Studies

2008