benzbromarone and lesinurad

benzbromarone has been researched along with lesinurad in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's4 (50.00)2.80

Authors

AuthorsStudies
Fu, P; Li, X; Liu, J; Ma, L1
Gallo, L; Hawkins, R; Jadhav, A; Parker, CG; Wang, WW1
Ai, W; Chen, Y; Dong, Y; Kang, D; Liang, R; Liu, X; Meng, Q; Pang, J; Sun, Z; Wu, T; Zhan, P; Zhao, T; Zhao, Z1
Ji, J; Liang, R; Liao, H; Liu, X; Pang, J; Shi, X; Tao, Y; Wu, T; Zhan, P; Zhang, J; Zhang, Z; Zhao, F; Zhao, T1
Cai, W; Liu, W; Liu, Y; Tang, L; Wang, J; Wu, J; Xie, Y; Xu, W; Zhang, S; Zhao, G1
Gillen, M; Hall, J; Ito, Y; Liu, S; Shen, Z; Shiramoto, M; Yamamoto, A; Yan, X1
Jansen, TL; Perez-Ruiz, F; Richette, P; Tausche, AK1
Borghi, C; Cicero, AFG; Fogacci, F; Kuwabara, M1

Reviews

4 review(s) available for benzbromarone and lesinurad

ArticleYear
Pharmacological urate-lowering approaches in chronic kidney disease.
    European journal of medicinal chemistry, 2019, Mar-15, Volume: 166

    Topics: Biological Products; Drug Discovery; Flavonoids; Humans; Renal Insufficiency, Chronic; Uric Acid

2019
The Druggability of Solute Carriers.
    Journal of medicinal chemistry, 2020, 04-23, Volume: 63, Issue:8

    Topics: Animals; Biological Transport; Cell Membrane; Drug Discovery; Humans; Metabolic Diseases; Nervous System Diseases; Protein Structure, Secondary; Protein Transport; Sodium-Glucose Transporter 2 Inhibitors; Solute Carrier Proteins

2020
International position paper on the appropriate use of uricosurics with the introduction of lesinurad.
    Clinical rheumatology, 2018, Volume: 37, Issue:12

    Topics: Benzbromarone; Europe; Febuxostat; Gout; Humans; International Cooperation; Practice Guidelines as Topic; Probenecid; Rheumatology; Thioglycolates; Triazoles; Uricosuric Agents; Xanthine Oxidase

2018
Therapeutic Strategies for the Treatment of Chronic Hyperuricemia: An Evidence-Based Update.
    Medicina (Kaunas, Lithuania), 2021, Jan-10, Volume: 57, Issue:1

    Topics: Acetamides; Allopurinol; Benzbromarone; Chronic Disease; Evidence-Based Medicine; Febuxostat; Gout Suppressants; Humans; Hyperuricemia; Naphthalenes; Nitriles; Phenylacetates; Polyethylene Glycols; Probenecid; Propionates; Pyridines; Thioglycolates; Triazoles; Urate Oxidase; Uricosuric Agents; Xanthine Oxidase

2021

Trials

1 trial(s) available for benzbromarone and lesinurad

ArticleYear
Verinurad combined with febuxostat in Japanese adults with gout or asymptomatic hyperuricaemia: a phase 2a, open-label study.
    Rheumatology (Oxford, England), 2018, 09-01, Volume: 57, Issue:9

    Topics: Administration, Oral; Adult; Aged; Benzbromarone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Febuxostat; Female; Follow-Up Studies; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Organic Anion Transporters; Organic Cation Transport Proteins; Thioglycolates; Time Factors; Treatment Outcome; Triazoles; Uric Acid; Uricosuric Agents; Young Adult

2018

Other Studies

3 other study(ies) available for benzbromarone and lesinurad

ArticleYear
Novel Human Urate Transporter 1 Inhibitors as Hypouricemic Drug Candidates with Favorable Druggability.
    Journal of medicinal chemistry, 2020, 10-08, Volume: 63, Issue:19

    Topics: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Gout; HEK293 Cells; Humans; Hyperuricemia; Mass Spectrometry; Mice; Organic Anion Transporters; Organic Cation Transport Proteins; Proton Magnetic Resonance Spectroscopy; Rats; Structure-Activity Relationship; Uricosuric Agents

2020
Discovery of Novel Bicyclic Imidazolopyridine-Containing Human Urate Transporter 1 Inhibitors as Hypouricemic Drug Candidates with Improved Efficacy and Favorable Druggability.
    Journal of medicinal chemistry, 2022, 03-10, Volume: 65, Issue:5

    Topics: Animals; Gout; Humans; Hyperuricemia; Mice; Organic Anion Transporters; Organic Cation Transport Proteins; Uric Acid

2022
Systematic Structure-Activity Relationship (SAR) Exploration of Diarylmethane Backbone and Discovery of A Highly Potent Novel Uric Acid Transporter 1 (URAT1) Inhibitor.
    Molecules (Basel, Switzerland), 2018, Jan-27, Volume: 23, Issue:2

    Topics: Benzbromarone; Biological Transport, Active; Carbon Radioisotopes; Drug Design; Gene Expression; HEK293 Cells; Humans; Methane; Organic Anion Transporters; Organic Cation Transport Proteins; Structure-Activity Relationship; Thioglycolates; Triazoles; Uric Acid; Uricosuric Agents

2018