benzbromarone has been researched along with indomethacin in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.70) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 13 (56.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beijnen, J; Borst, P; de Haas, M; Evers, R; Lankelma, J; Sparidans, R; Wielinga, PR | 1 |
| Beijnen, JH; Borst, P; Reid, G; Saeki, T; Zelcer, N | 1 |
| Boyd, CD; Iliás, A; Le Saux, O; Sarkadi, B; Seidl, TL; Sinkó, E; Urbán, Z; Váradi, A | 1 |
| Bai, J; Goh, BC; Lai, L; Tan, TM; Yeo, HC | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| König, HJ | 1 |
| Rodnan, GP | 1 |
| Fukuoka, M; Matsumoto, Y; Matsushita, R; Ohta, K; Shimizu, M; Suzuki, K; Tsuyuki, A; Yamamoto, C | 1 |
| Bacchelli, B; Boraldi, F; Croce, MA; Garcia Fernandez, MI; Gheduzzi, D; Pasquali Ronchetti, I; Quaglino, D; Tiozzo, R | 1 |
| Huang, HH; Lin, LH; Zhang, P; Zhong, DF | 1 |
| Anzai, N; Endou, H; Enomoto, A; Fujimura, M; Miyazaki, H; Shin, HJ; Takeda, M | 1 |
2 review(s) available for benzbromarone and indomethacin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Treatment of the gout and other forms of crystal-induced arthritis.
Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Benzbromarone; Colchicine; Gout; Gout Suppressants; Humans; Indomethacin; Kidney; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric Acid | 1982 |
21 other study(ies) available for benzbromarone and indomethacin
| Article | Year |
|---|---|
Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export.
Topics: Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Benzbromarone; Biological Transport, Active; Carrier Proteins; Dose-Response Relationship, Drug; Glutathione; Humans; Indomethacin; Probenecid; Sulfinpyrazone; Tumor Cells, Cultured; Uricosuric Agents; Vinblastine | 2000 |
Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3).
Topics: Animals; Biological Transport; Cell Line; Chromatography, High Pressure Liquid; Cloning, Molecular; DNA, Complementary; Drug Resistance, Multiple; Etoposide; Glutathione; Humans; Mice; Multidrug Resistance-Associated Proteins; Transfection | 2001 |
Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6).
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Biological Transport; Blotting, Western; Cell Line; Cell Membrane; DNA, Complementary; Dose-Response Relationship, Drug; Gene Library; Glutathione; Humans; Insecta; Kinetics; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Mutation; Mutation, Missense; Nucleotides; Protein Binding; Protein Biosynthesis; Pseudoxanthoma Elasticum; Time Factors; Transcription, Genetic | 2002 |
Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione.
Topics: Adenosine Triphosphate; Anions; Antimetabolites, Antineoplastic; Benzbromarone; Biological Transport; Biological Transport, Active; Bridged Bicyclo Compounds; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Dinitrochlorobenzene; Drug Resistance; Estradiol; Glutathione; Humans; Indomethacin; Methotrexate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Oxygen; Phosphorylation; Thioguanine; Time Factors; Transfection; Verapamil | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
[Therapy of gout].
Topics: Allopurinol; Arteriosclerosis; Benzbromarone; Colchicine; Gout; Humans; Immobilization; Indomethacin; Uric Acid | 1979 |
Effects of aspirin and/or salicylate on hydrolysis and glucuronidation of indomethacin in rat erythrocytes and hepatocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzbromarone; Carboxylesterase; Chromatography, High Pressure Liquid; Drug Interactions; Erythrocytes; Glucuronides; Hepatocytes; Hydrolysis; In Vitro Techniques; Indomethacin; Male; Microsomes, Liver; Rats; Rats, Wistar; Salicylates | 2003 |
Multidrug resistance protein-6 (MRP6) in human dermal fibroblasts. Comparison between cells from normal subjects and from Pseudoxanthoma elasticum patients.
Topics: Adult; Benzbromarone; Cell Count; Cell Division; Chlorambucil; Female; Fibroblasts; Fluoresceins; Fluorescent Dyes; Humans; Indomethacin; Lysosomes; Male; Membrane Transport Proteins; Microscopy, Fluorescence; Middle Aged; Multidrug Resistance-Associated Proteins; Propionates; Pseudoxanthoma Elasticum; Quinolines; Skin; Verapamil; Vinblastine | 2003 |
[The inhibition of CYP2C9 isoenzyme in Cunninghamella blakesleeana AS 3. 910].
Topics: Aryl Hydrocarbon Hydroxylases; Benzbromarone; Biotransformation; Catalysis; Chromatography, High Pressure Liquid; Cunninghamella; Cytochrome P-450 CYP2C9; Diclofenac; Dose-Response Relationship, Drug; Drug Interactions; Fungal Proteins; Indomethacin; Isoenzymes; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Sulfaphenazole; Tolbutamide; Valproic Acid | 2006 |
Interactions of urate transporter URAT1 in human kidney with uricosuric drugs.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Benzothiazoles; Biological Transport; Captopril; Cells, Cultured; Dogs; Enalapril; Indomethacin; Inhibitory Concentration 50; Organic Anion Transporters; Organic Cation Transport Proteins; Phenylbutazone; Probenecid; Pyridines; Salicylates; Sulfinpyrazone; Uric Acid; Uricosuric Agents | 2011 |