benzbromarone and colchicine

benzbromarone has been researched along with colchicine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.11)18.7374
1990's1 (3.70)18.2507
2000's4 (14.81)29.6817
2010's18 (66.67)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1
König, HJ1
Rodnan, GP1
Greiling, H; Kleesiek, K1
Bergmann, R; Center, MS; Couraud, PO; El Hafny, B; Koman, A; Piciotti, M; Regina, A; Roux, F1
Gröbner, W; Walter-Sack, I1
Gorter, KJ; Romeijnders, AC1
Wong, ML1
Taniguchi, A1
de Miguel, E; Mejía-Chew, C; Puig, JG; Torres, RJ1
Bombardier, C; Buchbinder, R; Edwards, CJ; Kydd, AS; Seth, R1
Dalbeth, N; Robinson, PC1
Stamp, LK1
Li, YJ; Perng, WT; Tseng, KY; Wang, YH; Wei, JC1

Reviews

6 review(s) available for benzbromarone and colchicine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Treatment of the gout and other forms of crystal-induced arthritis.
    Bulletin on the rheumatic diseases, 1982, Volume: 32, Issue:5

    Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Benzbromarone; Colchicine; Gout; Gout Suppressants; Humans; Indomethacin; Kidney; Phenylbutazone; Probenecid; Sulfinpyrazone; Uric Acid

1982
[Treatment of hyperuricemia and gout based on the guideline for the management of hyperuricemia and gout].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2010, Volume: 136, Issue:6

    Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Colchicine; Glucocorticoids; Gout; Gout Suppressants; Humans; Hyperuricemia; Life Style; Metabolic Syndrome; Practice Guidelines as Topic; Probenecid; Uricosuric Agents

2010
Allopurinol for chronic gout.
    The Cochrane database of systematic reviews, 2014, Oct-14, Issue:10

    Topics: Allopurinol; Benzbromarone; Chronic Disease; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Probenecid; Randomized Controlled Trials as Topic; Thiazoles; Uric Acid

2014
Advances in pharmacotherapy for the treatment of gout.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:4

    Topics: Adrenal Cortex Hormones; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzbromarone; Clinical Trials, Phase III as Topic; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Polyethylene Glycols; Probenecid; Thiazoles; Urate Oxidase; Uric Acid

2015
Major unanswered questions in the clinical gout field.
    Current opinion in rheumatology, 2017, Volume: 29, Issue:2

    Topics: Allopurinol; Benzbromarone; Colchicine; Disease Progression; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Patient Care Planning; Probenecid; Renal Insufficiency, Chronic; Uric Acid; Uricosuric Agents

2017

Other Studies

21 other study(ies) available for benzbromarone and colchicine

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020
[Therapy of gout].
    Fortschritte der Medizin, 1979, Aug-23, Volume: 97, Issue:32

    Topics: Allopurinol; Arteriosclerosis; Benzbromarone; Colchicine; Gout; Humans; Immobilization; Indomethacin; Uric Acid

1979
Effect of anti-inflammatory agents on the glycosaminoglycan metabolism in cultured human synovial cells.
    Rheumatology international, 1982, Volume: 2, Issue:4

    Topics: Adult; Aged; Anti-Inflammatory Agents; Benzbromarone; Cells, Cultured; Colchicine; Dose-Response Relationship, Drug; Fibrinolytic Agents; Flufenamic Acid; Gabexate; Glycosaminoglycans; Guanidines; Humans; In Vitro Techniques; Kinetics; Knee Joint; Male; Models, Biological; Protease Inhibitors; Synovial Membrane

1982
Mrp1 multidrug resistance-associated protein and P-glycoprotein expression in rat brain microvessel endothelial cells.
    Journal of neurochemistry, 1998, Volume: 71, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Astrocytes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzbromarone; Brain; Capillaries; Carcinogens; Cell Line, Transformed; Colchicine; Cyclosporine; DNA-Binding Proteins; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genistein; Gout Suppressants; Immunoblotting; Multidrug Resistance-Associated Proteins; MutS Homolog 3 Protein; Polymerase Chain Reaction; Probenecid; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfinpyrazone; Uricosuric Agents; Vinblastine; Vincristine

1998
[Hyperuricemia and gout--treatment].
    Deutsche medizinische Wochenschrift (1946), 2002, Feb-01, Volume: 127, Issue:5

    Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Colchicine; Drug Therapy, Combination; Glucocorticoids; Gout; Gout Suppressants; Humans; Kidney Calculi; Kidney Diseases; Probenecid; Time Factors; Uric Acid; Uricosuric Agents

2002
[Summary of the Dutch College of General Practitioners' "Gout" Standard].
    Nederlands tijdschrift voor geneeskunde, 2002, Feb-16, Volume: 146, Issue:7

    Topics: Acute Disease; Adrenal Cortex Hormones; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Chronic Disease; Colchicine; Gout; Gout Suppressants; Humans; Netherlands; Practice Guidelines as Topic; Recurrence; Uricosuric Agents

2002
Optimal management of chronic gout: attempting to render the (t)issues crystal-clear.
    The New Zealand medical journal, 2005, Jun-24, Volume: 118, Issue:1217

    Topics: Allopurinol; Anti-Inflammatory Agents; Benzbromarone; Chronic Disease; Colchicine; Drug Hypersensitivity; Gout; Humans; Uric Acid; Uricosuric Agents

2005
Resolution of massive tophaceous gout with three urate-lowering drugs.
    The American journal of medicine, 2013, Volume: 126, Issue:11

    Topics: Allopurinol; Benzbromarone; Colchicine; Drug Therapy, Combination; Gout; Gout Suppressants; Humans; Male; Middle Aged; Urate Oxidase

2013
Association of gout medications and risk of cataract: a population-based case-control study.
    QJM : monthly journal of the Association of Physicians, 2019, Nov-01, Volume: 112, Issue:11

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Allopurinol; Benzbromarone; Case-Control Studies; Cataract; Colchicine; Databases, Factual; Female; Gout; Gout Suppressants; Humans; Logistic Models; Male; Middle Aged; National Health Programs; Risk Factors; Taiwan; Young Adult

2019