benzbromarone and benzofurans

benzbromarone has been researched along with benzofurans in 86 studies

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-199079 (91.86)18.7374
1990's4 (4.65)18.2507
2000's2 (2.33)29.6817
2010's1 (1.16)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mertz, DP4
Martin, H; Oudot, J1
Didier, M; Olmer, M1
Fanelli, GM1
Avery, GS; Brogden, RN; Heel, RC; Speight, TM1
Matzkies, F3
Bosmanský, K; Trnavský, K1
Arntz, HR; Dreykluft, HR; Leonhardt, H1
Bresnik, W; Kuzmits, R; Müller, MM1
Barsom, S1
Giudicelli, C; Masbernard, A; Meunier, J; Ricordel, I; Schermann, JM1
Kleinschmidt, A; Schräpler, P; Schulz, E1
Haese, E; Kleinschmidt, A; Schräpler, P1
Göhmann, E; Mertz, DP1
Becher, H; Gerok, W; Mack, T1
Akaoka, I; Masuda, T; Nishida, Y; Nishizawa, T1
Bröll, H; Eberl, R; Sochor, H; Tausch, G1
Fox, IH; Sinclair, DS2
Bec, Ph; Pujo, JM; Suc, JM1
Berg, G; Matzkies, F2
Janzen, D; Kühnhold, O; Mertz, DP; Scheiffele, E1
Berg, G; Matzkies, F; Neuwirth, R1
Yu, TF1
Schräpler, P; Schulz, E1
Hada, T; Higashino, K; Moriwaki, Y; Takahashi, S; Yamamoto, T2
Gresser, U; Walter-Sack, I; Zöllner, N1
Maurer, H; Wollenberg, P1
De Vries, JX; Ittensohn, A; Walter-Sack, I; Weber, E1
Cabo, J; Gómez-Ruiz, MD; Izquierdo, R; Rodilla, F; Sánchez-Beltrán, MJ2
Clavel, JP; Colin, JN; Farinotti, R; Fredj, G; Nebout, T1
Buisse, JM; Demarez, JP1
de Vries, JX; Eichelbaum, M; Walter-Sack, I; Weber, E1
de Vries, JX; Ittensohn, A; Kohlmeier, M; Walter-Sack, I; Weber, E1
Babany, G; Benhamou, JP; Degott, C; Larrey, D; Pessayre, D; Rueff, B1
Hesse, A; Schneeberger, W; Vahlensieck, W1
Schoeman, HS; Sommers, DK1
de Vries, JX; Ittensohn, A; Walter-Sack, I1
Bonn, R; Chasseaud, LF; Darragh, A; Grote, H; John, BA; Lambe, RF; Sandrock, K; Wood, SG1
Malý, J1
Clavel, JP; Colin, JN; Dietlin, F; Farinotti, R; Fredj, G; Tod, M; Vignon, E1
de Vries, JX; Kocher, J; van de Loo, A; Walter-Sack, I1
Bösiger, G; Zwillenberg, HH; Zwillenberg, LO1
Lange, A; Paul, V1
Pevny, I1
Eichhorn, R; Mertz, DP1
Borner, K; Mertz, DP1
Betz, E; Knehr, HE1
Gröbner, W; Löffler, W; Zöllner, N1
Kronbach, T; Voelter, W1
Diehm, C; Mörl, H; Schöffel, G; Walter, E; Zimmermann, R1
Ehrly, AM; Landgraf, H; Saeger-Lorenz, K; Vogel, C1
Chandelier, C; Dupuich, Y; Niquet, G1
Buddecke, E; Schmidt, A; Staubesand, J1
Henkel, E; Mitzkat, HJ; Rüffer, C; Zorn, G1
Burck, G; Dauterstedt, W; Heidelmann, G; Heinrich, JJ; Ohlmer, R1
Brzozowska-Jurkowska, AM; Kawenoki-Minc, E1
Brzozowska-Jurkowska, AM1
Bluestone, R; Klinenberg, J; Lee, IK1
Bader, U; Ferber, H; Matzkies, F1
Scott, WA1
Schepers, GW1
Dorn, M1
Breithaupt, B; Tittel, M1
Blümel, G; Haas, S; Lill, G; von Eckstädt, AV; Weichenmeier, I1
Betz, E; Roth, J; Schlote, W1
Mascher, H; Nitsche, V1
Giudicelli, CP; Masbernard, A1
Ferber, H; Hitzenberger, G; Vergin, H1
Angar, T; Bach, GL; Grosse-Kielisch, C; Jelke, K; Jüttner, A; Krause, G; Neubauer, M1
Bishop, G; Vergin, H1
Danĕková, H; Dzúrik, R; Fedelesová, V; Hlavatá, E1
Bach, D; Hesse, A; Strenge, A; Vahlensieck, W1
Gumieniczek, A; Przyborowski, L1
Gasser, R; Hänni, A; Kaufmann, P; Krähenbühl, S; Roberts, P; Török, M1
Hu, K; Jeong, JH1
Elango, N; Johnson, K; Mills, BJ; Robertson, DH; Stevens, JL; Sutherland, JJ; Webster, YW1

Reviews

3 review(s) available for benzbromarone and benzofurans

ArticleYear
Urate excretion.
    Annual review of medicine, 1977, Volume: 28

    Topics: Acetohexamide; Animals; Benzbromarone; Benzofurans; Diuretics; Ethambutol; Halofenate; Humans; Mersalyl; Pan troglodytes; Probenecid; Salicylates; Sulfinpyrazone; Uric Acid; Zoxazolamine

1977
Benzbromarone: a review of its pharmacological properties and therapeutic use in gout and hyperuricaemia.
    Drugs, 1977, Volume: 14, Issue:5

    Topics: Aspirin; Benzbromarone; Benzofurans; Drug Interactions; Fasting; Gout; Humans; Kidney Diseases; Kinetics; Lipid Metabolism; Pyrazinamide; Triglycerides; Uric Acid; Xanthine Oxidase

1977
[Benzbromarone in the treatment of gout].
    Reumatologia, 1980, Volume: 18, Issue:1

    Topics: Benzbromarone; Benzofurans; Biological Availability; Chemical Phenomena; Chemistry; Gout; Half-Life; Humans; Time Factors; Uric Acid

1980

Trials

22 trial(s) available for benzbromarone and benzofurans

ArticleYear
[Hypouricemic effect of benzbromarone especially in kidney failure].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1978, Volume: 54, Issue:9-12

    Topics: Adolescent; Adult; Aged; Benzbromarone; Benzofurans; Clinical Trials as Topic; Depression, Chemical; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Uric Acid

1978
[Behavior of serum and urine sodium and potassium during treatment with benzbromarone].
    Fortschritte der Medizin, 1979, Jan-18, Volume: 97, Issue:3

    Topics: Adult; Benzbromarone; Benzofurans; Diuresis; Electrolytes; Humans; Male; Potassium; Sodium

1979
[Uric acid lowering effects of benzbromarone (Harolan) by increasing uric acid excretion].
    Fortschritte der Medizin, 1979, May-03, Volume: 97, Issue:17

    Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Female; Humans; Male; Middle Aged; Uric Acid

1979
[Effect of uric acid lowering drugs in low dosage in patients with hyperuricemia and hypertriglyceridemia in a randomized group study].
    Fortschritte der Medizin, 1979, Jul-19, Volume: 97, Issue:27

    Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Drug Combinations; Humans; Hyperlipidemias; Male; Middle Aged; Triglycerides; Uric Acid

1979
[The uricosuric effect of benzbromaron and probenecid under fasting conditions (author's transl)].
    Medizinische Klinik, 1978, Feb-17, Volume: 73, Issue:7

    Topics: Benzbromarone; Benzofurans; Dose-Response Relationship, Drug; Fasting; Female; Humans; Kidney Tubules; Male; p-Aminohippuric Acid; Probenecid; Uric Acid

1978
[The effect of benzbromarone on fasting-hyperuricemia as a model (author's transl)].
    Medizinische Klinik, 1978, Jun-09, Volume: 73, Issue:23

    Topics: Adolescent; Adult; Benzbromarone; Benzofurans; Fasting; Female; Humans; Male; Middle Aged; Obesity; Probenecid; Purines; Uric Acid

1978
[Reducing the risks in the treatment of gout and hyperuricaemia (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1976, Aug-27, Volume: 101, Issue:35

    Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Clinical Trials as Topic; Drug Combinations; Female; Gout; Humans; Male; Metabolic Clearance Rate; Middle Aged; Uric Acid

1976
[Therapy with alllopurinol and benzbromarone, single and combined. Renal elimination of lithogenous and colloid protective substances (author's transl)].
    Medizinische Klinik, 1977, Apr-15, Volume: 72, Issue:15

    Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Calcium; Citrates; Creatinine; Glomerular Filtration Rate; Gout; Humans; Magnesium; Male; Middle Aged; Natriuresis; Sodium; Uric Acid

1977
[Effect of benzbromarone in 100mg and 50mg doses on healthy subjects].
    Fortschritte der Medizin, 1977, Jul-21, Volume: 95, Issue:27

    Topics: Administration, Oral; Analysis of Variance; Benzbromarone; Benzofurans; Humans; Male; Uric Acid

1977
[Pathogenesis and treatment of fast-induced hyperuricemia using benzbromarone].
    Die Medizinische Welt, 1976, Mar-19, Volume: 27, Issue:12

    Topics: Adolescent; Adult; Benzbromarone; Benzofurans; Fasting; Female; Gout; Humans; Male; Middle Aged; Starvation; Uric Acid

1976
[Pharmacokinetic interaction between the active metabolite of allopurinol and benzbromarone].
    Presse medicale (Paris, France : 1983), 1986, Mar-22, Volume: 15, Issue:12

    Topics: Allopurinol; Benzbromarone; Benzofurans; Drug Interactions; Humans; Kinetics

1986
Benzbromarone disposition and uricosuric action; evidence for hydroxilation instead of debromination to benzarone.
    Klinische Wochenschrift, 1988, Feb-15, Volume: 66, Issue:4

    Topics: Adult; Benzbromarone; Benzofurans; Humans; Hydroxylation; Inactivation, Metabolic; Male; Protein Binding; Purines; Uric Acid

1988
[Benzarone for leg edema caused by chronic venous insufficiency].
    MMW, Munchener medizinische Wochenschrift, 1983, Apr-22, Volume: 125, Issue:16

    Topics: Benzbromarone; Benzofurans; Chronic Disease; Clinical Trials as Topic; Edema; Female; Fibrinolytic Agents; Humans; Leg; Male; Venous Insufficiency

1983
[Excretion and serum concentrations of allopurinol, oxipurinol and oxipurines in combined treatment with allopurinol and benzbromarone in increasing doses].
    Die Medizinische Welt, 1983, Sep-09, Volume: 34, Issue:36

    Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gout; Humans; Male; Metabolic Clearance Rate; Middle Aged; Oxypurinol; Purines; Pyrimidines

1983
[Effect of benziodarone and benzbromarone on the uric acid level in the blood and urine and on the incidence of gout attacks].
    Reumatologia, 1980, Volume: 18, Issue:3

    Topics: Adult; Aged; Benzbromarone; Benzofurans; Clinical Trials as Topic; Gout; Humans; Male; Middle Aged; Uric Acid

1980
Benzbromarone as a long-term uricosuric agent.
    Advances in experimental medicine and biology, 1980, Volume: 122A

    Topics: Benzbromarone; Benzofurans; Clinical Trials as Topic; Follow-Up Studies; Gout; Humans; Uric Acid

1980
The action of benzbromarone in relation to age, sex and accompanying diseases.
    Advances in experimental medicine and biology, 1980, Volume: 122A

    Topics: Benzbromarone; Benzofurans; Body Height; Body Weight; Clinical Trials as Topic; Female; Follow-Up Studies; Gout; Humans; Male; Uric Acid

1980
Benzbromarone therapy in hyperuricaemia.
    The Journal of international medical research, 1981, Volume: 9, Issue:1

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Benzbromarone; Benzofurans; Clinical Trials as Topic; Creatinine; Female; Humans; Male; Middle Aged; Uric Acid

1981
Benzbromarone therapy in hyperuricaemia; comparison with allopurinol and probenecid.
    The Journal of international medical research, 1981, Volume: 9, Issue:6

    Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Clinical Trials as Topic; Female; Humans; Male; Placebos; Probenecid; Uric Acid

1981
[The effect on uric acid and other laboratory parameters. A long-term study].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1982, Feb-20, Volume: 58, Issue:5

    Topics: Allopurinol; Benzbromarone; Benzofurans; Clinical Trials as Topic; Gout; Humans; Uric Acid

1982
[Drug modification of a risk factor of thrombosis in patients with varicosis].
    Fortschritte der Medizin, 1982, Aug-12, Volume: 100, Issue:30

    Topics: Adult; Aged; Benzbromarone; Benzofurans; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Premedication; Thrombosis; Varicose Veins

1982
[Prevention of urinary calculi by means of a benzbromarone-citrate combination].
    Fortschritte der Medizin, 1980, Nov-27, Volume: 98, Issue:44

    Topics: Adult; Aged; Benzbromarone; Benzofurans; Circadian Rhythm; Citrates; Drug Combinations; Humans; Hydrogen-Ion Concentration; Middle Aged; Uric Acid; Urinary Calculi

1980

Other Studies

61 other study(ies) available for benzbromarone and benzofurans

ArticleYear
[The uric acid-lowering action of benzbromarone effervescent granules and allopurinol. Comparative studies (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1978, Oct-20, Volume: 120, Issue:42

    Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Dosage Forms; Female; Humans; Male; Middle Aged; Uric Acid; Uricosuric Agents

1978
[Possible effect of Désuric on reported deafness in hyperuremic patients. Apropos of 30 cases].
    Journal francais d'oto-rhino-laryngologie; audiophonologie, chirurgie maxillo-faciale, 1979, Volume: 28, Issue:9

    Topics: Aged; Benzbromarone; Benzofurans; Deafness; Female; Humans; Male; Middle Aged; Uremia

1979
[Treating gout with benzbromarone (author's transl)].
    Casopis lekaru ceskych, 1979, Feb-02, Volume: 118, Issue:5

    Topics: Adult; Aged; Benzbromarone; Benzofurans; Female; Gout; Humans; Male; Middle Aged

1979
[The effect of benzbromaron in gout patients with limited kidney function].
    Fortschritte der Medizin, 1979, Nov-22, Volume: 97, Issue:44

    Topics: Adult; Aged; Benzbromarone; Benzofurans; Creatinine; Drug Evaluation; Gout; Humans; Kidney Diseases; Male; Middle Aged; Uric Acid

1979
[Allomaron in hyperuricemia and gout].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1979, Aug-31, Volume: 55, Issue:24

    Topics: Adolescent; Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Drug Combinations; Drug Evaluation; Female; Gout; Humans; Male; Middle Aged; Uric Acid

1979
[Comparative study of uric acid concentration in serum and saliva of healthy or hyperuricemic subjects].
    Annales de biologie clinique, 1977, Volume: 35, Issue:6

    Topics: Benzbromarone; Benzofurans; Humans; Methods; Saliva; Uric Acid

1977
[Allopurinol-benzbromarone combination. Renal excretion of various ions during high-dosage therapy using an allopurinol-benzbromarone combination].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1978, May-20, Volume: 54, Issue:14

    Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Drug Combinations; Humans; Ions; Kidney; Male; Urodynamics

1978
[Effects and side effects of benzbromaron in the initial treatment of hyperuricemia and gout. Results of a field study on 3899 patients].
    Fortschritte der Medizin, 1978, Aug-24, Volume: 96, Issue:32

    Topics: Benzbromarone; Benzofurans; Diarrhea; Female; Gout; Humans; Kidney Calculi; Male; Nausea; Uric Acid

1978
[Purine nucleotide synthesis in human liver an its influence by benzbromarone (author's transl)].
    Klinische Wochenschrift, 1978, Aug-15, Volume: 56, Issue:16

    Topics: Amidophosphoribosyltransferase; Benzbromarone; Benzofurans; Humans; Hypoxanthine Phosphoribosyltransferase; Liver; Purine Nucleotides

1978
Treatment of gout with alternate-day hypo-uricaemic drugs.
    Rheumatology and rehabilitation, 1978, Volume: 17, Issue:3

    Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Female; Gout; Humans; Male; Middle Aged; Sulfinpyrazone; Uric Acid

1978
[Long-term therapy with benzbromarone in uric arthritis].
    Wiener medizinische Wochenschrift (1946), 1975, Sep-19, Volume: 125, Issue:28

    Topics: Adult; Aged; Benzbromarone; Benzofurans; Diarrhea; Female; Gout; Humans; Leukopenia; Long-Term Care; Male; Middle Aged; Uric Acid

1975
The pharmacology of the hypouricemic effect of benzbromarone.
    Advances in experimental medicine and biology, 1977, Volume: 76B

    Topics: Aspirin; Benzbromarone; Benzofurans; Blood Proteins; Drug Interactions; Glomerular Filtration Rate; Kidney Tubules; Protein Binding; Pyrazinamide; Sulfinpyrazone; Uric Acid; Xanthine Oxidase

1977
[Mechanisms of action of benzbromarone. Study in 3 anephric subjects. Preliminary results in 3 cases].
    Semaine des hopitaux. Therapeutique, 1977, Volume: 53, Issue:4

    Topics: Adult; Benzbromarone; Benzofurans; Glomerulonephritis; Humans; Hypertension, Renal; Kidney Failure, Chronic; Male; Nephrectomy; Polycystic Kidney Diseases; Proteinuria; Pyelonephritis; Renal Dialysis; Uric Acid

1977
[Action of benzbromarone on the renal excretion of allantoin in normouricemic and hyperuricemic humans (author's transl)].
    Klinische Wochenschrift, 1977, Nov-01, Volume: 55, Issue:21

    Topics: Adult; Allantoin; Benzbromarone; Benzofurans; Female; Humans; Male; Uric Acid; Uricosuric Agents

1977
[Serum uric acid and uric acid elimination after benzbromarone therapy in patients with gout and hyperuricemia].
    Fortschritte der Medizin, 1976, Sep-16, Volume: 94, Issue:26

    Topics: Benzbromarone; Benzofurans; Gout; Humans; Uric Acid

1976
Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone.
    The Journal of rheumatology, 1976, Volume: 3, Issue:3

    Topics: Adult; Aged; Arthritis; Benzbromarone; Benzofurans; Chemical Phenomena; Chemistry; Chronic Disease; Gout; Humans; Hydrochlorothiazide; Kinetics; Middle Aged; Probenecid; Sulfinpyrazone; Uric Acid

1976
[Treatment of hyperuricaemia with a combination of allopurinol and benzbromaron (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1976, Oct-22, Volume: 101, Issue:43

    Topics: Allopurinol; Benzbromarone; Benzofurans; Drug Combinations; Gout; Humans; Time Factors; Uric Acid

1976
The pharmacology of hypouricemic effect of benzbromarone.
    The Journal of rheumatology, 1975, Volume: 2, Issue:4

    Topics: Adult; Aspirin; Benzbromarone; Benzofurans; Blood Proteins; Creatinine; Female; Gout; Humans; Male; Middle Aged; Protein Binding; Pyrazinamide; Sulfinpyrazone; Uric Acid; Uricosuric Agents

1975
Analysis of uric acid transport in renal tubules using benzbromarone and pyrazinamide.
    International journal of clinical pharmacology, therapy, and toxicology, 1990, Volume: 28, Issue:2

    Topics: Benzbromarone; Benzofurans; Glomerular Filtration Rate; Humans; Kidney Tubules; Male; Pyrazinamide; Uric Acid

1990
Deficient benzbromarone elimination: a familial disorder?
    Klinische Wochenschrift, 1990, Jan-19, Volume: 68, Issue:2

    Topics: Adult; Benzbromarone; Benzofurans; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Pedigree; Phenotype

1990
Urinary metabolites of benzbromarone in man.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:4

    Topics: Acetylation; Benzbromarone; Benzofurans; Biotransformation; Gas Chromatography-Mass Spectrometry; Humans

1990
The isolation, identification and structure of a new hydroxylated metabolite of benzbromarone in man.
    Xenobiotica; the fate of foreign compounds in biological systems, 1989, Volume: 19, Issue:12

    Topics: Adult; Benzbromarone; Benzofurans; Biotransformation; Chromatography, Gas; Chromatography, High Pressure Liquid; Humans; Hydroxylation; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Spectrophotometry, Ultraviolet

1989
Effect of probenecid and benzbromarone on gluconeogenesis in isolated rat liver cells.
    Revista espanola de fisiologia, 1989, Volume: 45, Issue:4

    Topics: Animals; Benzbromarone; Benzofurans; Cells, Cultured; Depression, Chemical; Gluconeogenesis; Liver; Male; NAD; Probenecid; Rats; Rats, Inbred Strains; Uricosuric Agents

1989
[Is there a drug interaction between allopurinol and benzbromarone?].
    Presse medicale (Paris, France : 1983), 1986, Apr-12, Volume: 15, Issue:15

    Topics: Allopurinol; Benzbromarone; Benzofurans; Drug Interactions; Humans

1986
Inhibition of purine catabolism by benzbromarone in isolated rat liver cells. Comparison with allopurinol and probenecid.
    Biochemical pharmacology, 1988, Oct-01, Volume: 37, Issue:19

    Topics: Allopurinol; Animals; Benzbromarone; Benzofurans; In Vitro Techniques; Liver; Male; Probenecid; Purines; Rats; Rats, Inbred Strains; Uric Acid

1988
Benzbromarone biotransformation is not related to polymorphic oxidation of sparteine.
    Klinische Wochenschrift, 1988, Nov-01, Volume: 66, Issue:21

    Topics: Adult; Benzbromarone; Benzofurans; Biotransformation; Debrisoquin; Humans; Male; Oxidation-Reduction; Phenotype; Polymorphism, Genetic; Sparteine

1988
Renal excretion of purine bases. Effects of probenecid, benzbromarone and pyrazinamide.
    Nephron, 1988, Volume: 48, Issue:2

    Topics: Adult; Benzbromarone; Benzofurans; Biological Transport, Active; Female; Humans; Hypoxanthine; Hypoxanthines; Kidney; Male; Probenecid; Purines; Pyrazinamide; Uric Acid; Xanthine; Xanthines

1988
Chronic active hepatitis caused by benzarone.
    Journal of hepatology, 1987, Volume: 5, Issue:3

    Topics: Alanine Transaminase; Benzbromarone; Benzofurans; Chemical and Drug Induced Liver Injury, Chronic; Female; Fibrinolytic Agents; Hepatitis, Chronic; Humans; Middle Aged

1987
[Effect of an allopurinol/benzbromaron preparation on the composition of urine in a circadian course].
    Klinische Wochenschrift, 1987, Mar-02, Volume: 65, Issue:5

    Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Calcium Oxalate; Circadian Rhythm; Drug Therapy, Combination; Female; Humans; Hydrogen-Ion Concentration; Kidney Calculi; Male; Uric Acid

1987
Drug interactions with urate excretion in man.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:5

    Topics: Adult; Ampicillin; Benzbromarone; Benzofurans; Drug Interactions; Humans; Kidney; Kinetics; Male; Probenecid; Pyrazinamide; Uric Acid

1987
Analysis of benzbromarone in human plasma and urine by high-performance liquid chromatography and gas chromatography-mass spectrometry.
    Journal of chromatography, 1987, Jul-03, Volume: 417, Issue:2

    Topics: Adult; Benzbromarone; Benzofurans; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans

1987
Metabolic fate of the thrombolytic agent benzarone in man: comparison with the rat and dog.
    Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:7

    Topics: Adult; Animals; Benzbromarone; Benzofurans; Bile; Biotransformation; Blood Proteins; Chromatography, High Pressure Liquid; Dogs; Feces; Fibrinolytic Agents; Humans; Intestinal Absorption; Kinetics; Male; Mass Spectrometry; Rats; Rats, Inbred Strains; Species Specificity

1987
[The effect of benzbromarone and its combination with hydrochlorothiazide on the renal excretion of uric acid and electrolytes].
    Casopis lekaru ceskych, 1986, Aug-22, Volume: 125, Issue:34

    Topics: Adult; Benzbromarone; Benzofurans; Female; Humans; Hydrochlorothiazide; Kidney; Male; Potassium; Sodium; Uric Acid

1986
Kinetics of allopurinol and oxipurinol after chronic oral administration. Interaction with benzbromarone.
    European journal of clinical pharmacology, 1986, Volume: 31, Issue:1

    Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Creatinine; Drug Interactions; Female; Half-Life; Humans; Kinetics; Male; Oxypurinol; Pyrimidines; Uric Acid

1986
Determination of benzarone in human plasma and urine by high-performance liquid chromatography and gas chromatography-mass spectrometry. Identification of the conjugates.
    Journal of chromatography, 1986, Oct-31, Volume: 382

    Topics: Adult; Arylsulfatases; Benzbromarone; Benzofurans; Biotransformation; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glucuronidase; Humans; Indicators and Reagents; Male

1986
[On the site of action of benzarone and some other agents influencing the intracellular concentration of cyclic nucleotides].
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:9

    Topics: Animals; Benzbromarone; Benzofurans; Binding Sites; Cyclic AMP; Cyclic GMP; Fibroblasts; Humans; In Vitro Techniques; Platelet Aggregation; Rats; Trout

1982
Benzaron allergy.
    Contact dermatitis, 1984, Volume: 11, Issue:2

    Topics: Benzbromarone; Benzofurans; Chemical Phenomena; Chemistry; Dermatitis, Contact; Female; Humans; Middle Aged

1984
Does benzbromarone in therapeutic doses raise renal excretion of oxipurinol?
    Klinische Wochenschrift, 1984, Dec-17, Volume: 62, Issue:24

    Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Creatinine; Drug Therapy, Combination; Glomerular Filtration Rate; Gout; Humans; Male; Middle Aged; Oxypurinol; Pyrimidines; Uric Acid

1984
[Effect of benzarone on the oxygen consumption and the mechanical activity of vascular smooth muscle].
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:2

    Topics: Animals; Benzbromarone; Benzofurans; Carotid Arteries; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxidative Phosphorylation; Oxygen Consumption; Portal Vein; Rabbits; Rats; Rats, Inbred Strains; Uncoupling Agents

1983
[Uric acid-lowering effect of a combination of benzbromarone and allopurinol--studies under standardized dietary conditions].
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:12

    Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Depression, Chemical; Diet; Erythrocytes; Female; Humans; Kidney; Male; Orotic Acid; Time Factors; Uric Acid

1983
High-performance liquid chromatographic comparison of in vivo and in vitro drug metabolism.
    Journal of chromatography, 1984, May-04, Volume: 290

    Topics: Animals; Benzbromarone; Benzofurans; Bile; Biotransformation; Body Fluids; Chromatography, High Pressure Liquid; Humans; In Vitro Techniques; Liver; Male; Mass Spectrometry; Pharmaceutical Preparations; Piperidines; Rabbits; Rats; Species Specificity

1984
[Pharmacotherapeutical action on arteriosclerotic vascular diseases with benzarone (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1980, Feb-22, Volume: 122, Issue:8

    Topics: Arteriosclerosis; Benzbromarone; Benzofurans; Cholesterol; Factor VIII; Humans; Intermittent Claudication; Male; Middle Aged; Plasminogen; Triglycerides; Uric Acid

1980
[Behavior of muscle tissue oxygen pressure in patients with severe intermittent claudication after oral administration of benzarone].
    Die Medizinische Welt, 1983, Mar-04, Volume: 34, Issue:9

    Topics: Benzbromarone; Benzofurans; Fibrinolytic Agents; Humans; Intermittent Claudication; Muscles; Oxygen Consumption

1983
[Current therapy: combined drug therapy of hyperuricemia, gout and alcohol induced fatty liver].
    Fortschritte der Medizin, 1983, May-12, Volume: 101, Issue:18

    Topics: Allopurinol; Benzbromarone; Benzofurans; Drug Therapy, Combination; Fatty Liver, Alcoholic; Gout; Humans; Hypoxanthine; Hypoxanthines; Uric Acid; Xanthine; Xanthines

1983
[Variations in fecal elimination of uric acid in 8 patients treated with benzbromarone].
    LARC medical, 1983, Volume: 3, Issue:3

    Topics: Adult; Benzbromarone; Benzofurans; Feces; Humans; Middle Aged; Uric Acid

1983
[Therapy of hyperuricemia and gout. Effect of a combination therapy of allopurinol with benzbromarone].
    Fortschritte der Medizin, 1983, May-26, Volume: 101, Issue:20

    Topics: Allopurinol; Benzbromarone; Benzofurans; Chemical Phenomena; Chemistry; Drug Therapy, Combination; Gout; Humans; Uric Acid

1983
[The effect of benzarone on serum lipids and arterial wall of cholesterol fed rats].
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:8

    Topics: Animals; Arteries; Benzbromarone; Benzofurans; Blood Pressure; Body Weight; Cholesterol, Dietary; Fibrinolytic Agents; Lipid Metabolism; Lipids; Male; Rats

1982
[Influence of benzbromarone on the pharmacokinetics and pharmacodynamics of oxipurinol].
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:9

    Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Drug Combinations; Glomerular Filtration Rate; Humans; Kinetics; Male; Oxypurinol; Pyrimidines

1982
[Indications for and methods of allopurinol-benzbromarone combination therapy in the treatment of hyperuricemic metabolic disorders].
    Zeitschrift fur arztliche Fortbildung, 1982, Mar-01, Volume: 76, Issue:5

    Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Drug Interactions; Drug Therapy, Combination; Gout; Humans; Kidney Failure, Chronic; Male; Middle Aged; Phenylbutazone

1982
Kinetics of allopurinol after single intravenous and oral doses. Noninteraction with benzbromarone and hydrochlorothiazide.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:1

    Topics: Administration, Oral; Adult; Allopurinol; Benzbromarone; Benzofurans; Biological Availability; Drug Interactions; Female; Humans; Hydrochlorothiazide; Injections, Intravenous; Kinetics; Male; Oxypurinol; Time Factors

1982
[Influence of 2-ethyl-3-(4-hydroxybenzoyl)-benzofuran (benzarone) on experimental atheromatosis (author's transl)].
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:11

    Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Benzbromarone; Benzofurans; Cholesterol; Electrodes, Implanted; In Vitro Techniques; Rabbits

1980
[Determination of benzbromarone in serum following combined therapy with allopurinol and benzbromarone (author's transl)].
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:3

    Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Chromatography, High Pressure Liquid; Drug Combinations; Female; Humans; Kinetics; Male

1981
Ten years' experience with benzbromarone in the management of gout and hyperuricaemia.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981, May-09, Volume: 59, Issue:20

    Topics: Adult; Aged; Benzbromarone; Benzofurans; Female; Follow-Up Studies; Gout; Humans; Male; Middle Aged; Time Factors; Uric Acid

1981
Pharmacokinetics and biotransformation of benzbromarone in man.
    European journal of clinical pharmacology, 1981, Volume: 19, Issue:6

    Topics: Adult; Benzbromarone; Benzofurans; Biotransformation; Half-Life; Humans; Intestinal Absorption; Kinetics

1981
[Efficacy and tolerance of a new benzbromarone preparation].
    Die Medizinische Welt, 1980, May-23, Volume: 31, Issue:21

    Topics: Benzbromarone; Benzofurans; Gout; Humans; Hydrogen-Ion Concentration; Uric Acid; Urine

1980
High-performance liquid chromatographic determination of benzbromarone and the main metabolite benzarone in serum.
    Journal of chromatography, 1980, Sep-12, Volume: 183, Issue:3

    Topics: Benzbromarone; Benzofurans; Chromatography, High Pressure Liquid; Half-Life; Humans; Kinetics

1980
[Clinical followup of the uricosuric drug--benzbromaron (author's transl)].
    Bratislavske lekarske listy, 1980, Volume: 74, Issue:5

    Topics: Benzbromarone; Benzofurans; Humans; Uric Acid

1980
Thin-layer chromatographic analysis of some benzofuran derivatives in human plasma.
    Acta poloniae pharmaceutica, 1994, Volume: 51, Issue:6

    Topics: Amiodarone; Benzbromarone; Benzofurans; Chromatography, Thin Layer; Fibrinolytic Agents; Humans; Uricosuric Agents; Vasodilator Agents

1994
Mechanisms of benzarone and benzbromarone-induced hepatic toxicity.
    Hepatology (Baltimore, Md.), 2005, Volume: 41, Issue:4

    Topics: Amiodarone; Animals; Apoptosis; Benzbromarone; Benzofurans; Cell Line, Tumor; Hepatocytes; Ketone Bodies; Liver; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Molecular Structure; Necrosis; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2005
A convergent synthetic study of biologically active benzofuran derivatives.
    Archives of pharmacal research, 2006, Volume: 29, Issue:6

    Topics: Benzbromarone; Benzofurans; Combinatorial Chemistry Techniques; Uricosuric Agents

2006
A Novel Open Access Web Portal for Integrating Mechanistic and Toxicogenomic Study Results.
    Toxicological sciences : an official journal of the Society of Toxicology, 2019, 08-01, Volume: 170, Issue:2

    Topics: Access to Information; Benzbromarone; Benzofurans; Humans; Internet; Liver; Omeprazole; Phenotype; Toxicogenetics; Transcriptome; Triglycerides

2019