benzbromarone has been researched along with benzofurans in 86 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 79 (91.86) | 18.7374 |
1990's | 4 (4.65) | 18.2507 |
2000's | 2 (2.33) | 29.6817 |
2010's | 1 (1.16) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Mertz, DP | 4 |
Martin, H; Oudot, J | 1 |
Didier, M; Olmer, M | 1 |
Fanelli, GM | 1 |
Avery, GS; Brogden, RN; Heel, RC; Speight, TM | 1 |
Matzkies, F | 3 |
Bosmanský, K; Trnavský, K | 1 |
Arntz, HR; Dreykluft, HR; Leonhardt, H | 1 |
Bresnik, W; Kuzmits, R; Müller, MM | 1 |
Barsom, S | 1 |
Giudicelli, C; Masbernard, A; Meunier, J; Ricordel, I; Schermann, JM | 1 |
Kleinschmidt, A; Schräpler, P; Schulz, E | 1 |
Haese, E; Kleinschmidt, A; Schräpler, P | 1 |
Göhmann, E; Mertz, DP | 1 |
Becher, H; Gerok, W; Mack, T | 1 |
Akaoka, I; Masuda, T; Nishida, Y; Nishizawa, T | 1 |
Bröll, H; Eberl, R; Sochor, H; Tausch, G | 1 |
Fox, IH; Sinclair, DS | 2 |
Bec, Ph; Pujo, JM; Suc, JM | 1 |
Berg, G; Matzkies, F | 2 |
Janzen, D; Kühnhold, O; Mertz, DP; Scheiffele, E | 1 |
Berg, G; Matzkies, F; Neuwirth, R | 1 |
Yu, TF | 1 |
Schräpler, P; Schulz, E | 1 |
Hada, T; Higashino, K; Moriwaki, Y; Takahashi, S; Yamamoto, T | 2 |
Gresser, U; Walter-Sack, I; Zöllner, N | 1 |
Maurer, H; Wollenberg, P | 1 |
De Vries, JX; Ittensohn, A; Walter-Sack, I; Weber, E | 1 |
Cabo, J; Gómez-Ruiz, MD; Izquierdo, R; Rodilla, F; Sánchez-Beltrán, MJ | 2 |
Clavel, JP; Colin, JN; Farinotti, R; Fredj, G; Nebout, T | 1 |
Buisse, JM; Demarez, JP | 1 |
de Vries, JX; Eichelbaum, M; Walter-Sack, I; Weber, E | 1 |
de Vries, JX; Ittensohn, A; Kohlmeier, M; Walter-Sack, I; Weber, E | 1 |
Babany, G; Benhamou, JP; Degott, C; Larrey, D; Pessayre, D; Rueff, B | 1 |
Hesse, A; Schneeberger, W; Vahlensieck, W | 1 |
Schoeman, HS; Sommers, DK | 1 |
de Vries, JX; Ittensohn, A; Walter-Sack, I | 1 |
Bonn, R; Chasseaud, LF; Darragh, A; Grote, H; John, BA; Lambe, RF; Sandrock, K; Wood, SG | 1 |
Malý, J | 1 |
Clavel, JP; Colin, JN; Dietlin, F; Farinotti, R; Fredj, G; Tod, M; Vignon, E | 1 |
de Vries, JX; Kocher, J; van de Loo, A; Walter-Sack, I | 1 |
Bösiger, G; Zwillenberg, HH; Zwillenberg, LO | 1 |
Lange, A; Paul, V | 1 |
Pevny, I | 1 |
Eichhorn, R; Mertz, DP | 1 |
Borner, K; Mertz, DP | 1 |
Betz, E; Knehr, HE | 1 |
Gröbner, W; Löffler, W; Zöllner, N | 1 |
Kronbach, T; Voelter, W | 1 |
Diehm, C; Mörl, H; Schöffel, G; Walter, E; Zimmermann, R | 1 |
Ehrly, AM; Landgraf, H; Saeger-Lorenz, K; Vogel, C | 1 |
Chandelier, C; Dupuich, Y; Niquet, G | 1 |
Buddecke, E; Schmidt, A; Staubesand, J | 1 |
Henkel, E; Mitzkat, HJ; Rüffer, C; Zorn, G | 1 |
Burck, G; Dauterstedt, W; Heidelmann, G; Heinrich, JJ; Ohlmer, R | 1 |
Brzozowska-Jurkowska, AM; Kawenoki-Minc, E | 1 |
Brzozowska-Jurkowska, AM | 1 |
Bluestone, R; Klinenberg, J; Lee, IK | 1 |
Bader, U; Ferber, H; Matzkies, F | 1 |
Scott, WA | 1 |
Schepers, GW | 1 |
Dorn, M | 1 |
Breithaupt, B; Tittel, M | 1 |
Blümel, G; Haas, S; Lill, G; von Eckstädt, AV; Weichenmeier, I | 1 |
Betz, E; Roth, J; Schlote, W | 1 |
Mascher, H; Nitsche, V | 1 |
Giudicelli, CP; Masbernard, A | 1 |
Ferber, H; Hitzenberger, G; Vergin, H | 1 |
Angar, T; Bach, GL; Grosse-Kielisch, C; Jelke, K; Jüttner, A; Krause, G; Neubauer, M | 1 |
Bishop, G; Vergin, H | 1 |
Danĕková, H; Dzúrik, R; Fedelesová, V; Hlavatá, E | 1 |
Bach, D; Hesse, A; Strenge, A; Vahlensieck, W | 1 |
Gumieniczek, A; Przyborowski, L | 1 |
Gasser, R; Hänni, A; Kaufmann, P; Krähenbühl, S; Roberts, P; Török, M | 1 |
Hu, K; Jeong, JH | 1 |
Elango, N; Johnson, K; Mills, BJ; Robertson, DH; Stevens, JL; Sutherland, JJ; Webster, YW | 1 |
3 review(s) available for benzbromarone and benzofurans
Article | Year |
---|---|
Urate excretion.
Topics: Acetohexamide; Animals; Benzbromarone; Benzofurans; Diuretics; Ethambutol; Halofenate; Humans; Mersalyl; Pan troglodytes; Probenecid; Salicylates; Sulfinpyrazone; Uric Acid; Zoxazolamine | 1977 |
Benzbromarone: a review of its pharmacological properties and therapeutic use in gout and hyperuricaemia.
Topics: Aspirin; Benzbromarone; Benzofurans; Drug Interactions; Fasting; Gout; Humans; Kidney Diseases; Kinetics; Lipid Metabolism; Pyrazinamide; Triglycerides; Uric Acid; Xanthine Oxidase | 1977 |
[Benzbromarone in the treatment of gout].
Topics: Benzbromarone; Benzofurans; Biological Availability; Chemical Phenomena; Chemistry; Gout; Half-Life; Humans; Time Factors; Uric Acid | 1980 |
22 trial(s) available for benzbromarone and benzofurans
Article | Year |
---|---|
[Hypouricemic effect of benzbromarone especially in kidney failure].
Topics: Adolescent; Adult; Aged; Benzbromarone; Benzofurans; Clinical Trials as Topic; Depression, Chemical; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Uric Acid | 1978 |
[Behavior of serum and urine sodium and potassium during treatment with benzbromarone].
Topics: Adult; Benzbromarone; Benzofurans; Diuresis; Electrolytes; Humans; Male; Potassium; Sodium | 1979 |
[Uric acid lowering effects of benzbromarone (Harolan) by increasing uric acid excretion].
Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Female; Humans; Male; Middle Aged; Uric Acid | 1979 |
[Effect of uric acid lowering drugs in low dosage in patients with hyperuricemia and hypertriglyceridemia in a randomized group study].
Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Drug Combinations; Humans; Hyperlipidemias; Male; Middle Aged; Triglycerides; Uric Acid | 1979 |
[The uricosuric effect of benzbromaron and probenecid under fasting conditions (author's transl)].
Topics: Benzbromarone; Benzofurans; Dose-Response Relationship, Drug; Fasting; Female; Humans; Kidney Tubules; Male; p-Aminohippuric Acid; Probenecid; Uric Acid | 1978 |
[The effect of benzbromarone on fasting-hyperuricemia as a model (author's transl)].
Topics: Adolescent; Adult; Benzbromarone; Benzofurans; Fasting; Female; Humans; Male; Middle Aged; Obesity; Probenecid; Purines; Uric Acid | 1978 |
[Reducing the risks in the treatment of gout and hyperuricaemia (author's transl)].
Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Clinical Trials as Topic; Drug Combinations; Female; Gout; Humans; Male; Metabolic Clearance Rate; Middle Aged; Uric Acid | 1976 |
[Therapy with alllopurinol and benzbromarone, single and combined. Renal elimination of lithogenous and colloid protective substances (author's transl)].
Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Calcium; Citrates; Creatinine; Glomerular Filtration Rate; Gout; Humans; Magnesium; Male; Middle Aged; Natriuresis; Sodium; Uric Acid | 1977 |
[Effect of benzbromarone in 100mg and 50mg doses on healthy subjects].
Topics: Administration, Oral; Analysis of Variance; Benzbromarone; Benzofurans; Humans; Male; Uric Acid | 1977 |
[Pathogenesis and treatment of fast-induced hyperuricemia using benzbromarone].
Topics: Adolescent; Adult; Benzbromarone; Benzofurans; Fasting; Female; Gout; Humans; Male; Middle Aged; Starvation; Uric Acid | 1976 |
[Pharmacokinetic interaction between the active metabolite of allopurinol and benzbromarone].
Topics: Allopurinol; Benzbromarone; Benzofurans; Drug Interactions; Humans; Kinetics | 1986 |
Benzbromarone disposition and uricosuric action; evidence for hydroxilation instead of debromination to benzarone.
Topics: Adult; Benzbromarone; Benzofurans; Humans; Hydroxylation; Inactivation, Metabolic; Male; Protein Binding; Purines; Uric Acid | 1988 |
[Benzarone for leg edema caused by chronic venous insufficiency].
Topics: Benzbromarone; Benzofurans; Chronic Disease; Clinical Trials as Topic; Edema; Female; Fibrinolytic Agents; Humans; Leg; Male; Venous Insufficiency | 1983 |
[Excretion and serum concentrations of allopurinol, oxipurinol and oxipurines in combined treatment with allopurinol and benzbromarone in increasing doses].
Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gout; Humans; Male; Metabolic Clearance Rate; Middle Aged; Oxypurinol; Purines; Pyrimidines | 1983 |
[Effect of benziodarone and benzbromarone on the uric acid level in the blood and urine and on the incidence of gout attacks].
Topics: Adult; Aged; Benzbromarone; Benzofurans; Clinical Trials as Topic; Gout; Humans; Male; Middle Aged; Uric Acid | 1980 |
Benzbromarone as a long-term uricosuric agent.
Topics: Benzbromarone; Benzofurans; Clinical Trials as Topic; Follow-Up Studies; Gout; Humans; Uric Acid | 1980 |
The action of benzbromarone in relation to age, sex and accompanying diseases.
Topics: Benzbromarone; Benzofurans; Body Height; Body Weight; Clinical Trials as Topic; Female; Follow-Up Studies; Gout; Humans; Male; Uric Acid | 1980 |
Benzbromarone therapy in hyperuricaemia.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Benzbromarone; Benzofurans; Clinical Trials as Topic; Creatinine; Female; Humans; Male; Middle Aged; Uric Acid | 1981 |
Benzbromarone therapy in hyperuricaemia; comparison with allopurinol and probenecid.
Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Clinical Trials as Topic; Female; Humans; Male; Placebos; Probenecid; Uric Acid | 1981 |
[The effect on uric acid and other laboratory parameters. A long-term study].
Topics: Allopurinol; Benzbromarone; Benzofurans; Clinical Trials as Topic; Gout; Humans; Uric Acid | 1982 |
[Drug modification of a risk factor of thrombosis in patients with varicosis].
Topics: Adult; Aged; Benzbromarone; Benzofurans; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Premedication; Thrombosis; Varicose Veins | 1982 |
[Prevention of urinary calculi by means of a benzbromarone-citrate combination].
Topics: Adult; Aged; Benzbromarone; Benzofurans; Circadian Rhythm; Citrates; Drug Combinations; Humans; Hydrogen-Ion Concentration; Middle Aged; Uric Acid; Urinary Calculi | 1980 |
61 other study(ies) available for benzbromarone and benzofurans
Article | Year |
---|---|
[The uric acid-lowering action of benzbromarone effervescent granules and allopurinol. Comparative studies (author's transl)].
Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Dosage Forms; Female; Humans; Male; Middle Aged; Uric Acid; Uricosuric Agents | 1978 |
[Possible effect of Désuric on reported deafness in hyperuremic patients. Apropos of 30 cases].
Topics: Aged; Benzbromarone; Benzofurans; Deafness; Female; Humans; Male; Middle Aged; Uremia | 1979 |
[Treating gout with benzbromarone (author's transl)].
Topics: Adult; Aged; Benzbromarone; Benzofurans; Female; Gout; Humans; Male; Middle Aged | 1979 |
[The effect of benzbromaron in gout patients with limited kidney function].
Topics: Adult; Aged; Benzbromarone; Benzofurans; Creatinine; Drug Evaluation; Gout; Humans; Kidney Diseases; Male; Middle Aged; Uric Acid | 1979 |
[Allomaron in hyperuricemia and gout].
Topics: Adolescent; Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Drug Combinations; Drug Evaluation; Female; Gout; Humans; Male; Middle Aged; Uric Acid | 1979 |
[Comparative study of uric acid concentration in serum and saliva of healthy or hyperuricemic subjects].
Topics: Benzbromarone; Benzofurans; Humans; Methods; Saliva; Uric Acid | 1977 |
[Allopurinol-benzbromarone combination. Renal excretion of various ions during high-dosage therapy using an allopurinol-benzbromarone combination].
Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Drug Combinations; Humans; Ions; Kidney; Male; Urodynamics | 1978 |
[Effects and side effects of benzbromaron in the initial treatment of hyperuricemia and gout. Results of a field study on 3899 patients].
Topics: Benzbromarone; Benzofurans; Diarrhea; Female; Gout; Humans; Kidney Calculi; Male; Nausea; Uric Acid | 1978 |
[Purine nucleotide synthesis in human liver an its influence by benzbromarone (author's transl)].
Topics: Amidophosphoribosyltransferase; Benzbromarone; Benzofurans; Humans; Hypoxanthine Phosphoribosyltransferase; Liver; Purine Nucleotides | 1978 |
Treatment of gout with alternate-day hypo-uricaemic drugs.
Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Female; Gout; Humans; Male; Middle Aged; Sulfinpyrazone; Uric Acid | 1978 |
[Long-term therapy with benzbromarone in uric arthritis].
Topics: Adult; Aged; Benzbromarone; Benzofurans; Diarrhea; Female; Gout; Humans; Leukopenia; Long-Term Care; Male; Middle Aged; Uric Acid | 1975 |
The pharmacology of the hypouricemic effect of benzbromarone.
Topics: Aspirin; Benzbromarone; Benzofurans; Blood Proteins; Drug Interactions; Glomerular Filtration Rate; Kidney Tubules; Protein Binding; Pyrazinamide; Sulfinpyrazone; Uric Acid; Xanthine Oxidase | 1977 |
[Mechanisms of action of benzbromarone. Study in 3 anephric subjects. Preliminary results in 3 cases].
Topics: Adult; Benzbromarone; Benzofurans; Glomerulonephritis; Humans; Hypertension, Renal; Kidney Failure, Chronic; Male; Nephrectomy; Polycystic Kidney Diseases; Proteinuria; Pyelonephritis; Renal Dialysis; Uric Acid | 1977 |
[Action of benzbromarone on the renal excretion of allantoin in normouricemic and hyperuricemic humans (author's transl)].
Topics: Adult; Allantoin; Benzbromarone; Benzofurans; Female; Humans; Male; Uric Acid; Uricosuric Agents | 1977 |
[Serum uric acid and uric acid elimination after benzbromarone therapy in patients with gout and hyperuricemia].
Topics: Benzbromarone; Benzofurans; Gout; Humans; Uric Acid | 1976 |
Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone.
Topics: Adult; Aged; Arthritis; Benzbromarone; Benzofurans; Chemical Phenomena; Chemistry; Chronic Disease; Gout; Humans; Hydrochlorothiazide; Kinetics; Middle Aged; Probenecid; Sulfinpyrazone; Uric Acid | 1976 |
[Treatment of hyperuricaemia with a combination of allopurinol and benzbromaron (author's transl)].
Topics: Allopurinol; Benzbromarone; Benzofurans; Drug Combinations; Gout; Humans; Time Factors; Uric Acid | 1976 |
The pharmacology of hypouricemic effect of benzbromarone.
Topics: Adult; Aspirin; Benzbromarone; Benzofurans; Blood Proteins; Creatinine; Female; Gout; Humans; Male; Middle Aged; Protein Binding; Pyrazinamide; Sulfinpyrazone; Uric Acid; Uricosuric Agents | 1975 |
Analysis of uric acid transport in renal tubules using benzbromarone and pyrazinamide.
Topics: Benzbromarone; Benzofurans; Glomerular Filtration Rate; Humans; Kidney Tubules; Male; Pyrazinamide; Uric Acid | 1990 |
Deficient benzbromarone elimination: a familial disorder?
Topics: Adult; Benzbromarone; Benzofurans; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Pedigree; Phenotype | 1990 |
Urinary metabolites of benzbromarone in man.
Topics: Acetylation; Benzbromarone; Benzofurans; Biotransformation; Gas Chromatography-Mass Spectrometry; Humans | 1990 |
The isolation, identification and structure of a new hydroxylated metabolite of benzbromarone in man.
Topics: Adult; Benzbromarone; Benzofurans; Biotransformation; Chromatography, Gas; Chromatography, High Pressure Liquid; Humans; Hydroxylation; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Spectrophotometry, Ultraviolet | 1989 |
Effect of probenecid and benzbromarone on gluconeogenesis in isolated rat liver cells.
Topics: Animals; Benzbromarone; Benzofurans; Cells, Cultured; Depression, Chemical; Gluconeogenesis; Liver; Male; NAD; Probenecid; Rats; Rats, Inbred Strains; Uricosuric Agents | 1989 |
[Is there a drug interaction between allopurinol and benzbromarone?].
Topics: Allopurinol; Benzbromarone; Benzofurans; Drug Interactions; Humans | 1986 |
Inhibition of purine catabolism by benzbromarone in isolated rat liver cells. Comparison with allopurinol and probenecid.
Topics: Allopurinol; Animals; Benzbromarone; Benzofurans; In Vitro Techniques; Liver; Male; Probenecid; Purines; Rats; Rats, Inbred Strains; Uric Acid | 1988 |
Benzbromarone biotransformation is not related to polymorphic oxidation of sparteine.
Topics: Adult; Benzbromarone; Benzofurans; Biotransformation; Debrisoquin; Humans; Male; Oxidation-Reduction; Phenotype; Polymorphism, Genetic; Sparteine | 1988 |
Renal excretion of purine bases. Effects of probenecid, benzbromarone and pyrazinamide.
Topics: Adult; Benzbromarone; Benzofurans; Biological Transport, Active; Female; Humans; Hypoxanthine; Hypoxanthines; Kidney; Male; Probenecid; Purines; Pyrazinamide; Uric Acid; Xanthine; Xanthines | 1988 |
Chronic active hepatitis caused by benzarone.
Topics: Alanine Transaminase; Benzbromarone; Benzofurans; Chemical and Drug Induced Liver Injury, Chronic; Female; Fibrinolytic Agents; Hepatitis, Chronic; Humans; Middle Aged | 1987 |
[Effect of an allopurinol/benzbromaron preparation on the composition of urine in a circadian course].
Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Calcium Oxalate; Circadian Rhythm; Drug Therapy, Combination; Female; Humans; Hydrogen-Ion Concentration; Kidney Calculi; Male; Uric Acid | 1987 |
Drug interactions with urate excretion in man.
Topics: Adult; Ampicillin; Benzbromarone; Benzofurans; Drug Interactions; Humans; Kidney; Kinetics; Male; Probenecid; Pyrazinamide; Uric Acid | 1987 |
Analysis of benzbromarone in human plasma and urine by high-performance liquid chromatography and gas chromatography-mass spectrometry.
Topics: Adult; Benzbromarone; Benzofurans; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans | 1987 |
Metabolic fate of the thrombolytic agent benzarone in man: comparison with the rat and dog.
Topics: Adult; Animals; Benzbromarone; Benzofurans; Bile; Biotransformation; Blood Proteins; Chromatography, High Pressure Liquid; Dogs; Feces; Fibrinolytic Agents; Humans; Intestinal Absorption; Kinetics; Male; Mass Spectrometry; Rats; Rats, Inbred Strains; Species Specificity | 1987 |
[The effect of benzbromarone and its combination with hydrochlorothiazide on the renal excretion of uric acid and electrolytes].
Topics: Adult; Benzbromarone; Benzofurans; Female; Humans; Hydrochlorothiazide; Kidney; Male; Potassium; Sodium; Uric Acid | 1986 |
Kinetics of allopurinol and oxipurinol after chronic oral administration. Interaction with benzbromarone.
Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Creatinine; Drug Interactions; Female; Half-Life; Humans; Kinetics; Male; Oxypurinol; Pyrimidines; Uric Acid | 1986 |
Determination of benzarone in human plasma and urine by high-performance liquid chromatography and gas chromatography-mass spectrometry. Identification of the conjugates.
Topics: Adult; Arylsulfatases; Benzbromarone; Benzofurans; Biotransformation; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glucuronidase; Humans; Indicators and Reagents; Male | 1986 |
[On the site of action of benzarone and some other agents influencing the intracellular concentration of cyclic nucleotides].
Topics: Animals; Benzbromarone; Benzofurans; Binding Sites; Cyclic AMP; Cyclic GMP; Fibroblasts; Humans; In Vitro Techniques; Platelet Aggregation; Rats; Trout | 1982 |
Benzaron allergy.
Topics: Benzbromarone; Benzofurans; Chemical Phenomena; Chemistry; Dermatitis, Contact; Female; Humans; Middle Aged | 1984 |
Does benzbromarone in therapeutic doses raise renal excretion of oxipurinol?
Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Creatinine; Drug Therapy, Combination; Glomerular Filtration Rate; Gout; Humans; Male; Middle Aged; Oxypurinol; Pyrimidines; Uric Acid | 1984 |
[Effect of benzarone on the oxygen consumption and the mechanical activity of vascular smooth muscle].
Topics: Animals; Benzbromarone; Benzofurans; Carotid Arteries; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxidative Phosphorylation; Oxygen Consumption; Portal Vein; Rabbits; Rats; Rats, Inbred Strains; Uncoupling Agents | 1983 |
[Uric acid-lowering effect of a combination of benzbromarone and allopurinol--studies under standardized dietary conditions].
Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Depression, Chemical; Diet; Erythrocytes; Female; Humans; Kidney; Male; Orotic Acid; Time Factors; Uric Acid | 1983 |
High-performance liquid chromatographic comparison of in vivo and in vitro drug metabolism.
Topics: Animals; Benzbromarone; Benzofurans; Bile; Biotransformation; Body Fluids; Chromatography, High Pressure Liquid; Humans; In Vitro Techniques; Liver; Male; Mass Spectrometry; Pharmaceutical Preparations; Piperidines; Rabbits; Rats; Species Specificity | 1984 |
[Pharmacotherapeutical action on arteriosclerotic vascular diseases with benzarone (author's transl)].
Topics: Arteriosclerosis; Benzbromarone; Benzofurans; Cholesterol; Factor VIII; Humans; Intermittent Claudication; Male; Middle Aged; Plasminogen; Triglycerides; Uric Acid | 1980 |
[Behavior of muscle tissue oxygen pressure in patients with severe intermittent claudication after oral administration of benzarone].
Topics: Benzbromarone; Benzofurans; Fibrinolytic Agents; Humans; Intermittent Claudication; Muscles; Oxygen Consumption | 1983 |
[Current therapy: combined drug therapy of hyperuricemia, gout and alcohol induced fatty liver].
Topics: Allopurinol; Benzbromarone; Benzofurans; Drug Therapy, Combination; Fatty Liver, Alcoholic; Gout; Humans; Hypoxanthine; Hypoxanthines; Uric Acid; Xanthine; Xanthines | 1983 |
[Variations in fecal elimination of uric acid in 8 patients treated with benzbromarone].
Topics: Adult; Benzbromarone; Benzofurans; Feces; Humans; Middle Aged; Uric Acid | 1983 |
[Therapy of hyperuricemia and gout. Effect of a combination therapy of allopurinol with benzbromarone].
Topics: Allopurinol; Benzbromarone; Benzofurans; Chemical Phenomena; Chemistry; Drug Therapy, Combination; Gout; Humans; Uric Acid | 1983 |
[The effect of benzarone on serum lipids and arterial wall of cholesterol fed rats].
Topics: Animals; Arteries; Benzbromarone; Benzofurans; Blood Pressure; Body Weight; Cholesterol, Dietary; Fibrinolytic Agents; Lipid Metabolism; Lipids; Male; Rats | 1982 |
[Influence of benzbromarone on the pharmacokinetics and pharmacodynamics of oxipurinol].
Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Drug Combinations; Glomerular Filtration Rate; Humans; Kinetics; Male; Oxypurinol; Pyrimidines | 1982 |
[Indications for and methods of allopurinol-benzbromarone combination therapy in the treatment of hyperuricemic metabolic disorders].
Topics: Adult; Aged; Allopurinol; Benzbromarone; Benzofurans; Drug Interactions; Drug Therapy, Combination; Gout; Humans; Kidney Failure, Chronic; Male; Middle Aged; Phenylbutazone | 1982 |
Kinetics of allopurinol after single intravenous and oral doses. Noninteraction with benzbromarone and hydrochlorothiazide.
Topics: Administration, Oral; Adult; Allopurinol; Benzbromarone; Benzofurans; Biological Availability; Drug Interactions; Female; Humans; Hydrochlorothiazide; Injections, Intravenous; Kinetics; Male; Oxypurinol; Time Factors | 1982 |
[Influence of 2-ethyl-3-(4-hydroxybenzoyl)-benzofuran (benzarone) on experimental atheromatosis (author's transl)].
Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Benzbromarone; Benzofurans; Cholesterol; Electrodes, Implanted; In Vitro Techniques; Rabbits | 1980 |
[Determination of benzbromarone in serum following combined therapy with allopurinol and benzbromarone (author's transl)].
Topics: Adult; Allopurinol; Benzbromarone; Benzofurans; Chromatography, High Pressure Liquid; Drug Combinations; Female; Humans; Kinetics; Male | 1981 |
Ten years' experience with benzbromarone in the management of gout and hyperuricaemia.
Topics: Adult; Aged; Benzbromarone; Benzofurans; Female; Follow-Up Studies; Gout; Humans; Male; Middle Aged; Time Factors; Uric Acid | 1981 |
Pharmacokinetics and biotransformation of benzbromarone in man.
Topics: Adult; Benzbromarone; Benzofurans; Biotransformation; Half-Life; Humans; Intestinal Absorption; Kinetics | 1981 |
[Efficacy and tolerance of a new benzbromarone preparation].
Topics: Benzbromarone; Benzofurans; Gout; Humans; Hydrogen-Ion Concentration; Uric Acid; Urine | 1980 |
High-performance liquid chromatographic determination of benzbromarone and the main metabolite benzarone in serum.
Topics: Benzbromarone; Benzofurans; Chromatography, High Pressure Liquid; Half-Life; Humans; Kinetics | 1980 |
[Clinical followup of the uricosuric drug--benzbromaron (author's transl)].
Topics: Benzbromarone; Benzofurans; Humans; Uric Acid | 1980 |
Thin-layer chromatographic analysis of some benzofuran derivatives in human plasma.
Topics: Amiodarone; Benzbromarone; Benzofurans; Chromatography, Thin Layer; Fibrinolytic Agents; Humans; Uricosuric Agents; Vasodilator Agents | 1994 |
Mechanisms of benzarone and benzbromarone-induced hepatic toxicity.
Topics: Amiodarone; Animals; Apoptosis; Benzbromarone; Benzofurans; Cell Line, Tumor; Hepatocytes; Ketone Bodies; Liver; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Molecular Structure; Necrosis; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2005 |
A convergent synthetic study of biologically active benzofuran derivatives.
Topics: Benzbromarone; Benzofurans; Combinatorial Chemistry Techniques; Uricosuric Agents | 2006 |
A Novel Open Access Web Portal for Integrating Mechanistic and Toxicogenomic Study Results.
Topics: Access to Information; Benzbromarone; Benzofurans; Humans; Internet; Liver; Omeprazole; Phenotype; Toxicogenetics; Transcriptome; Triglycerides | 2019 |