Compounds > benzbromarone

benzbromarone and 6-hydroxybenzbromarone

benzbromarone has been researched along with 6-hydroxybenzbromarone in 8 studies

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (25.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	5 (62.50)	24.3611
2020's	1 (12.50)	2.80

Authors

Authors	Studies
Anzai, N; Endou, H; Frick, MM; Iwen, TJ; Jutabha, P; Quade, B; Rice, PJ; Ross, IR; Wempe, MF	1
Ashizawa, N; Iwanaga, T; Kobashi, S; Matsumoto, K; Miyata, S; Uda, J	1
Ackermann, M; De Vries, JX; Forster, W; Ilisistegui Pons, P; Moyna, G; Spraul, M; Stoetzer, F; Voss, A; Walter-Sack, I	1
de Vries, JX; Empl, H; Gresser, U; Ittensohn, A; Walter-Sack, I; Weber, E; Zöllner, N	1
Imai, H; Inui, N; Ishizaki, T; Katoh, Y; Misaka, S; Namiki, N; Ohashi, K; Shimada, K; Takeuchi, K; Uchida, S; Watanabe, H; Yamada, S	1
Anzai, N; Endou, H; Enomoto, A; Fujimura, M; Miyazaki, H; Shin, HJ; Takeda, M	1
Chiba, K; Ishikawa, M; Kajiwara, E; Kobayashi, K; Oka, H	1
Hegde, RS; McDonald, MG; Pandey, RN; Rettie, AE; Tadjuidje, E; Wang, TS	1

Other Studies

8 other study(ies) available for benzbromarone and 6-hydroxybenzbromarone

Article	Year
Developing potent human uric acid transporter 1 (hURAT1) inhibitors. Journal of medicinal chemistry, 2011, Apr-28, Volume: 54, Issue:8 Topics: Animals; Drug Design; Humans; Kidney; Magnetic Resonance Spectroscopy; Organic Anion Transporters; Organic Cation Transport Proteins; Xenopus	2011
Discovery of Dotinurad (FYU-981), a New Phenol Derivative with Highly Potent Uric Acid Lowering Activity. ACS medicinal chemistry letters, 2020, Oct-08, Volume: 11, Issue:10 Topics:	2020
Metabolism of benzbromarone in man: structures of new oxidative metabolites, 6-hydroxy- and 1'-oxo-benzbromarone, and the enantioselective formation and elimination of 1'-hydroxybenzbromarone. Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:12 Topics: Adult; Benzbromarone; Biotransformation; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Stereoisomerism	1993
Benzbromarone hydroxylation in man: defective formation of the 6-hydroxybenzbromarone metabolite. The Clinical investigator, 1993, Volume: 71, Issue:11 Topics: Administration, Oral; Adult; Benzbromarone; Diet; Female; Humans; Hydroxylation; Male; Phenotype; Uric Acid	1993
Benzbromarone pharmacokinetics and pharmacodynamics in different cytochrome P450 2C9 genotypes. Drug metabolism and pharmacokinetics, 2010, Volume: 25, Issue:6 Topics: Adult; Aryl Hydrocarbon Hydroxylases; Benzbromarone; Cytochrome P-450 CYP2C9; Genotype; Humans; Uricosuric Agents	2010
Interactions of urate transporter URAT1 in human kidney with uricosuric drugs. Nephrology (Carlton, Vic.), 2011, Volume: 16, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Benzothiazoles; Biological Transport; Captopril; Cells, Cultured; Dogs; Enalapril; Indomethacin; Inhibitory Concentration 50; Organic Anion Transporters; Organic Cation Transport Proteins; Phenylbutazone; Probenecid; Pyridines; Salicylates; Sulfinpyrazone; Uric Acid; Uricosuric Agents	2011
Identification of CYP isozymes involved in benzbromarone metabolism in human liver microsomes. Biopharmaceutics & drug disposition, 2012, Volume: 33, Issue:8 Topics: Benzbromarone; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Isoenzymes; Microsomes, Liver; Recombinant Proteins; Uricosuric Agents	2012
Structure-activity relationships of benzbromarone metabolites and derivatives as EYA inhibitory anti-angiogenic agents. PloS one, 2013, Volume: 8, Issue:12 Topics: Analysis of Variance; Angiogenesis Inhibitors; Animals; Benzbromarone; Cell Movement; DNA-Binding Proteins; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred C57BL; Microtubules; Molecular Structure; Neovascularization, Physiologic; Protein Tyrosine Phosphatases; Structure-Activity Relationship	2013