Page last updated: 2024-08-25

benzamidoxime and guanoxabenz

benzamidoxime has been researched along with guanoxabenz in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Bittner, F; Clement, B; Gruenewald, S; Hungeling, H; Kanzow, S; Kotthaus, J; Mendel, RR; Schwering, U; Wahl, B1
Clement, B; Indorf, P; Kubitza, C; Kunze, T; Scheidig, AJ1
Clement, B; Deters, S; Havemeyer, A; Mau, S1

Other Studies

3 other study(ies) available for benzamidoxime and guanoxabenz

ArticleYear
The fourth molybdenum containing enzyme mARC: cloning and involvement in the activation of N-hydroxylated prodrugs.
    Journal of medicinal chemistry, 2008, Dec-25, Volume: 51, Issue:24

    Topics: Animals; Benzamidines; Cattle; Cell Line; Chemistry, Pharmaceutical; Cloning, Molecular; Cytochrome-B(5) Reductase; Drug Design; Humans; Ligands; Models, Chemical; Molybdenum; Oxidoreductases; Prodrugs; Recombinant Proteins; Temperature

2008
Drug Metabolism by the Mitochondrial Amidoxime Reducing Component (mARC): Rapid Assay and Identification of New Substrates.
    Journal of medicinal chemistry, 2020, 06-25, Volume: 63, Issue:12

    Topics: Biological Assay; Humans; Inactivation, Metabolic; Metabolic Clearance Rate; Mitochondria; Mitochondrial Proteins; Oxidation-Reduction; Oxidoreductases; Oximes; Substrate Specificity

2020
Hepatic, extrahepatic, microsomal, and mitochondrial activation of the N-hydroxylated prodrugs benzamidoxime, guanoxabenz, and Ro 48-3656 ([[1-[(2s)-2-[[4-[(hydroxyamino)iminomethyl]benzoyl]amino]-1-oxopropyl]-4-piperidinyl]oxy]-acetic acid).
    Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:11

    Topics: Animals; Benzamidines; Cytochrome P-450 Enzyme System; Cytochrome-B(5) Reductase; Cytochromes b5; Guanabenz; Heterocyclic Compounds; Humans; In Vitro Techniques; Kidney; Kinetics; Liver; Microsomes, Liver; Mitochondria; Oximes; Prodrugs; Swine

2005