Page last updated: 2024-08-17

benz(a)anthracene and phenobarbital

benz(a)anthracene has been researched along with phenobarbital in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19909 (47.37)18.7374
1990's8 (42.11)18.2507
2000's2 (10.53)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Bock, KW; Bock-Hennig, BS; Fischer, G; Lilienblum, W; Schirmer, G1
Corcos, L; Weiss, MC1
Francis, JE; Smith, AG1
Grimmer, G; Hamann, M; Jacob, J; Raab, G; Schmoldt, A1
Chiu, PL; Yang, SK1
Fang, WF; Strobel, HW1
Berliner, JA; Duthu, GS; Hankinson, O; Nestor, MS; Philpot, RM1
Gelboin, HV; Kiefer, F; Park, SS; Wiebel, FJ1
De Graeve, J; Gielen, JE; Goujon, F; Kremers, P; Van Cantfort, J1
Geng, J; Strobel, HW2
Grant, MH; Li, SJ; Rodgers, EH1
Burke, MD; Doostdar, H; Grant, MH; Melvin, WT; Wolf, CR1
Dubois, M; Kremers, P; Roelandt, L; Thome, JP; Todaro, A1
Alber, J; Gebhardt, R; Wegner, H1
Dubois, M; Kremers, P; Plaisance, H; Thomé, JP1
Chui, YC; He, SX; Law, FC1
Strobel, H; Vasquez, H1

Reviews

1 review(s) available for benz(a)anthracene and phenobarbital

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

18 other study(ies) available for benz(a)anthracene and phenobarbital

ArticleYear
UDP-glucuronyltransferases and their toxicological significance.
    Advances in experimental medicine and biology, 1986, Volume: 197

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Cell Line; DNA Replication; Glucuronosyltransferase; Inactivation, Metabolic; Isoenzymes; Kinetics; Liver Regeneration; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Phenobarbital; Rats; Substrate Specificity

1986
Phenobarbital, dexamethasone and benzanthracene induce several cytochrome P450 mRNAs in rat hepatoma cells.
    FEBS letters, 1988, Jun-06, Volume: 233, Issue:1

    Topics: Animals; Benz(a)Anthracenes; Cell Differentiation; Cytochrome P-450 Enzyme System; Dexamethasone; Gene Expression Regulation; Liver Neoplasms, Experimental; Male; Nucleic Acid Hybridization; Phenobarbital; Rats; Rats, Inbred ACI; RNA, Messenger

1988
Polycyclic aromatic hydrocarbons cause hepatic porphyria in iron-loaded C57BL/10 mice: comparison of uroporphyrinogen decarboxylase inhibition with induction of alkoxyphenoxazone dealkylations.
    Biochemical and biophysical research communications, 1987, Jul-15, Volume: 146, Issue:1

    Topics: Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carboxy-Lyases; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Iron; Male; Mice; Mice, Inbred C57BL; Oxidoreductases; Phenobarbital; Polycyclic Compounds; Porphyrias; Safrole; Uroporphyrinogen Decarboxylase

1987
Monooxygenase induction by various xenobiotics and its influence on the rat liver microsomal metabolite profile of benz[a]anthracene.
    Cancer letters, 1985, Volume: 27, Issue:1

    Topics: Animals; Benz(a)Anthracenes; Enzyme Induction; Female; Male; Microsomes, Liver; Oxygenases; Pesticides; Phenobarbital; Polycyclic Compounds; Rats; Rats, Inbred Strains; Sex Factors

1985
Cytochrome P-450-catalyzed stereoselective epoxidation at the K region of benz[a]anthracene and benzo[a]pyrene.
    Archives of biochemistry and biophysics, 1985, Aug-01, Volume: 240, Issue:2

    Topics: Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Epoxy Compounds; Ethers, Cyclic; Isoenzymes; Male; Mathematics; Methylcholanthrene; Microsomes, Liver; NADP; Phenobarbital; Rats; Rats, Inbred Strains; Stereoisomerism

1985
Effects of cyclophosphamide and polycyclic aromatic hydrocarbons on cell growth and mixed-function oxidase activity in a human colon tumor cell line.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Adenocarcinoma; Anthracenes; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Cell Division; Cell Line; Colonic Neoplasms; Cyclophosphamide; Cytochrome P-450 Enzyme System; Humans; Hydrocortisone; Hydroxylation; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital

1982
Characterization of NADPH-cytochrome P-450 reductase in a mouse hepatoma cell line.
    Cancer letters, 1983, Volume: 18, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Cell Line; Enzyme Induction; Fluorescent Antibody Technique; Kinetics; Liver Neoplasms; Mice; NADPH-Ferrihemoprotein Reductase; Neoplasms, Experimental; Phenobarbital; Polychlorinated Dibenzodioxins; Rats

1983
Expression of cytochromes P-450 in rat hepatoma cells. Analysis by monoclonal antibodies specific for cytochromes P-450 from rat liver induced by 3-methylcholanthrene or phenobarbital.
    European journal of biochemistry, 1984, Dec-17, Volume: 145, Issue:3

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Cell Line; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Immunochemistry; Liver Neoplasms, Experimental; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains

1984
Multiplicity of cytochrome P-450 in primary fetal hepatocytes in culture.
    European journal of biochemistry, 1981, Volume: 116, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Cells, Cultured; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Female; Fetus; Kinetics; Liver; Phenobarbital; Pregnancy; Rats

1981
Identification of cytochromes P450 1A2, 2A1, 2C7, 2E1 in rat glioma C6 cell line by RT-PCR and specific restriction enzyme digestion.
    Biochemical and biophysical research communications, 1993, Dec-30, Volume: 197, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Benz(a)Anthracenes; Brain; Cell Line; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; DNA Primers; Enzyme Induction; Glioma; Male; Molecular Sequence Data; Oxidoreductases; Phenobarbital; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Restriction Mapping; RNA-Directed DNA Polymerase; RNA, Messenger; Steroid Hydroxylases; Tumor Cells, Cultured

1993
The activity of xenobiotic enzymes and the cytotoxicity of mitoxantrone in MCF 7 human breast cancer cells treated with inducing agents.
    Chemico-biological interactions, 1995, Jul-14, Volume: 97, Issue:2

    Topics: Benz(a)Anthracenes; Breast Neoplasms; Cell Death; Cytochrome P-450 Enzyme System; Dexamethasone; Dicumarol; Enzyme Induction; Female; Glutathione; Glutathione Peroxidase; Humans; L-Lactate Dehydrogenase; Metyrapone; Mitoxantrone; NAD(P)H Dehydrogenase (Quinone); NADPH-Ferrihemoprotein Reductase; Phenobarbital; Rifampin; Tumor Cells, Cultured; Xenobiotics

1995
The effects of inducing agents on cytochrome P450 and UDP-glucuronyltransferase activities in human HEPG2 hepatoma cells.
    Biochemical pharmacology, 1993, Aug-17, Volume: 46, Issue:4

    Topics: Benz(a)Anthracenes; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Glucuronosyltransferase; Humans; Mixed Function Oxygenases; Phenobarbital; Rifampin; Tumor Cells, Cultured

1993
Effect of inducers and PCBs on the cytochrome P450 enzymes in cultured quail hepatocytes.
    Ecotoxicology and environmental safety, 1995, Volume: 31, Issue:2

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aroclors; Benz(a)Anthracenes; Blotting, Western; Carcinogens; Cells, Cultured; Chlorodiphenyl (54% Chlorine); Coturnix; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Environmental Exposure; Enzyme Induction; Female; Isoenzymes; Liver; Microsomes, Liver; Molecular Weight; Oxidoreductases; Phenobarbital; Polychlorinated Biphenyls

1995
Perifusion of co-cultured hepatocytes: optimization of studies on drug metabolism and cytotoxicity in vitro.
    Cell biology and toxicology, 1996, Volume: 12, Issue:2

    Topics: Animals; Benz(a)Anthracenes; Biotransformation; Cell Culture Techniques; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Cytotoxins; Diffusion Chambers, Culture; Enzyme Induction; Liver; Male; Methylcholanthrene; Oxidoreductases; Phenobarbital; Rats; Rats, Sprague-Dawley

1996
Hierarchical cluster analysis of environmental pollutants through P450 induction in cultured hepatic cells.
    Ecotoxicology and environmental safety, 1996, Volume: 34, Issue:3

    Topics: 7-Alkoxycoumarin O-Dealkylase; Analysis of Variance; Animals; Antibody Specificity; Benz(a)Anthracenes; Blotting, Western; Carcinoma, Hepatocellular; Cells, Cultured; Cluster Analysis; Coturnix; Cytochrome P-450 CYP1A1; Environmental Pollutants; Enzyme Induction; Hexachlorocyclohexane; Humans; Insecticides; L-Lactate Dehydrogenase; Liver; Liver Neoplasms; Pentachlorophenol; Phenobarbital; Polychlorinated Biphenyls; Rats; Tumor Cells, Cultured

1996
Expression and induction of cytochrome P-450 1A1 and P-450 2D subfamily in the rat glioma C6 cell line.
    Brain research, 1997, Nov-07, Volume: 774, Issue:1-2

    Topics: Animals; Benz(a)Anthracenes; Brain Neoplasms; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Glioma; Male; Phenobarbital; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Cells, Cultured

1997
Biotransformation and elimination of 1-nitropyrene in the isolated perfused lung: effects of pretreating rats with phenobarbitone, beta-naphthoflavone, benz(A)anthracene or their mixtures.
    Yao xue xue bao = Acta pharmaceutica Sinica, 1996, Volume: 31, Issue:8

    Topics: Animals; Benz(a)Anthracenes; beta-Naphthoflavone; Biotransformation; Enzyme Inhibitors; In Vitro Techniques; Lung; Male; Mutagens; Perfusion; Phenobarbital; Pyrenes; Rats; Rats, Wistar

1996
Role of cytochrome P450 in DNA damage produced by treatment of colon cells with 1,2-dimethylhydrazine.
    International journal of oncology, 2001, Volume: 18, Issue:3

    Topics: 1,2-Dimethylhydrazine; Benz(a)Anthracenes; Carcinogens; Colon; Cytochrome P-450 Enzyme System; DNA; DNA Damage; Enzyme Activators; Glutathione; Guanine; Humans; Hypnotics and Sedatives; Methyltransferases; Phenobarbital; Pyrazoles

2001