benserazide has been researched along with methyldopa in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (9.38) | 29.6817 |
| 2010's | 5 (15.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Avdeef, A; Tam, KY | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Dollery, CT; Kersting, F; Reid, JL | 2 |
| Gierlichs, HW; Hawlina, A; Planz, G; Planz, R; Rahn, KH; Stephany, W | 1 |
| Chouinard, G; Jones, BD | 1 |
| Duvoisin, RC; Mytilineou, C | 1 |
| Feuerstein, C; Gavend, M; Pellat, J; Perret, J; Serre, F; Tanche, M | 2 |
| Combépine, C; Geissbühler, F; Hovaguimian, T; Raffin, Y; Streiff, U | 1 |
| Ernst, AM | 1 |
| Thut, PD | 1 |
| Goodale, DB; Moore, KE | 1 |
| Geissbühler, F; Widmer, J | 1 |
| De Jong, W; Ezer, J; Nijkamp, FP | 1 |
| Bobik, A; Jackman, G; Jennings, G; Korner, P; Oddie, C | 1 |
| Dhasmana, KM; Spilker, BA | 1 |
| Day, MD; Roach, AG; Whiting, RL | 1 |
| Antonaccio, MJ; Burrell, R; Robson, RD | 1 |
| Bartholini, G; Constantinidis, J; de Ajuriaguerra, J; Eisenring, JJ; Geissbühler, F; Tissot, R; Yanniotis, G | 1 |
| Paparo, AA; Tate, SS | 1 |
| Lesieur-Demarquilly, I; Mizon, J; Osteux, R | 1 |
| Cohen, Y; Jacquot, C; Rapin, J; Wepierre, J | 1 |
| Daniele, E; Zamboni, P | 1 |
| Dean, RC; Murphy, JA; Paparo, AA | 1 |
| Da Prada, M; Haefely, WE; Keller, HH; Kettler, R; Pieri, L | 1 |
| Fekete, MI; Fülöp, F; Homicskó, KG; Kertész, I; Nagy, GM; Radnai, B; Tóth, BE; Tóth, G | 1 |
| Crevoisier, C; Metzger, B; Monreal, A; Nilsen, T | 1 |
| Parada, A; Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
| Fisher, R; Jackson, MJ; Jenner, P; Rose, S; Tayarani-Binazir, KA; Zoubiane, G | 1 |
| Bonfim, RR; Byrro, RM; Cardoso, FF; César, Ida C; da Silva, EP; Gomes, SA; Mundim, IM; Pianetti, GA; Teixeira, Lde S | 1 |
2 review(s) available for benserazide and methyldopa
| Article | Year |
|---|---|
Compulsive gnawing.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Behavior, Animal; Benserazide; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Iproniazid; Levodopa; Male; Methyldopa; Methyltyrosines; Rats; Serotonin; Structure-Activity Relationship; Time Factors | 1976 |
The pharmacology of Parkinson's disease: basic aspects and recent advances.
Topics: Animals; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain; Bromocriptine; Carbidopa; Corpus Striatum; Dopamine; Ergolines; Humans; Kidney; Kinetics; Levodopa; Lisuride; Liver; Methyldopa; Norepinephrine; Parkinson Disease; Pergolide; Receptors, Dopamine; Selegiline; Serotonin; Stereotyped Behavior; Substantia Nigra; Tyramine | 1984 |
5 trial(s) available for benserazide and methyldopa
| Article | Year |
|---|---|
Clinical and cardiovascular effects of alpha methyldopa in combination with decarboxylase inhibitors.
Topics: Adult; Benserazide; Blood Pressure; Carbidopa; Carboxy-Lyases; Clinical Trials as Topic; Cold Temperature; Drug Interactions; Drug Therapy, Combination; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Hypnotics and Sedatives; Male; Methyldopa; Middle Aged; Salivation; Valsalva Maneuver | 1977 |
Influence of the decarboxylase inhibitor benserazide on the antihypertensive effect and metabolism of alpha-methyldopa in patients with essential hypertension.
Topics: Adult; Benserazide; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Female; Humans; Hydrazines; Hypertension; Male; Methyldopa; Middle Aged; Placebos | 1977 |
Evidence of brain dopamine deficiency in schizophrenia.
Topics: Benserazide; Brain; Chlorpromazine; Dopamine; Double-Blind Method; Drug Therapy, Combination; Humans; Methyldopa; Receptors, Dopamine; Rubidium; Schizophrenia; Serotonin; Tryptophan | 1979 |
Evidence for a predominantly central hypotensive effect of alpha-methyldopa in humans.
Topics: Adult; Benserazide; Biological Availability; Blood Pressure; Blood-Brain Barrier; Female; Half-Life; Hemodynamics; Humans; Hypertension; Isoleucine; Male; Methyldopa; Middle Aged; Norepinephrine; Random Allocation | 1986 |
Comparative single- and multiple-dose pharmacokinetics of levodopa and 3-O-methyldopa following a new dual-release and a conventional slow-release formulation of levodopa and benserazide in healthy volunteers.
Topics: Adult; Antiparkinson Agents; Benserazide; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Delayed-Action Preparations; Dopamine Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Humans; Levodopa; Male; Methyldopa; Reference Values | 2003 |
25 other study(ies) available for benserazide and methyldopa
| Article | Year |
|---|---|
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Site of action of methyldopa in lowering the blood pressure in man.
Topics: Benserazide; Binding Sites; Blood Pressure; Carbidopa; Depression, Chemical; Humans; Methyldopa | 1978 |
Where is L-DOPA decarboxylated in the striatum after 6-hydroxydopamine nigrotomy?
Topics: Animals; Benserazide; Blood-Brain Barrier; Capillaries; Corpus Striatum; Decarboxylation; Dopamine; Endothelium; Female; Humans; Hydroxydopamines; Levodopa; Methyldopa; Premedication; Rats; Receptors, Dopamine; Stereotyped Behavior; Substantia Nigra | 1978 |
Plasma O-methyldopa in levodopa-induced dyskinesias. A bioclinical investigation.
Topics: Aged; Benserazide; Carbidopa; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Methyldopa; Middle Aged; Parkinson Disease | 1977 |
[Endogenous 3-O-methyldopa in man: normal level and effect of an inhibitor of aromatic amino-acid decarboxylase (Benserazid) (author's transl)].
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Humans; Hydrazines; Methyldopa; Spectrometry, Fluorescence | 1978 |
Does O-methyl-dopa play a role in levodopa-induced dyskinesias?
Topics: Adult; Aged; Benserazide; Carbidopa; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Methyldopa; Middle Aged; Parkinson Disease | 1977 |
Effect of L-DOPA analogues in Sidman avoidance performance in mice.
Topics: Animals; Avoidance Learning; Benserazide; Brain; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Levodopa; Male; Methyldopa; Mice; Motor Activity; Norepinephrine; Serotonin | 1977 |
A comparison of the effects of decarboxylase inhibitors on L-dopa-induced circling behavior and the conversion of dopa to dopamine in the brain.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Benserazide; Brain; Brocresine; Carbidopa; Dopamine; Hydrazines; Levodopa; Male; Methyldopa; Rats; Time Factors | 1976 |
[Urinary excretion of 3,4-dihydroxyphenyl-alanine, 3-O-methyldopa, dopamine and homovanillic acid in man. Effects of an inhibitor of decarboxylase of aromatic amino acids (Benserazide) (author's transl)].
Topics: Adult; Benserazide; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Humans; Hydrazines; Male; Methyldopa; Phenylacetates; Time Factors | 1976 |
Central inhibitory effect of alpha-methyldopa on blood pressure, heart rate and body temperature of renal hypertensive rats.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Pressure; Body Temperature; Depression, Chemical; Heart Rate; Hypertension, Renal; Male; Methyldopa; Rats | 1975 |
On the mechanism of L-dopa-induced postural hypotension in the cat.
Topics: Adrenergic alpha-Antagonists; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Pressure; Carotid Arteries; Cats; Chemoreceptor Cells; Dihydroxyphenylalanine; Dogs; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Ganglia, Autonomic; Ganglionic Blockers; Intestines; Kidney; Male; Methyldopa; Posture; Pressoreceptors; Rats; Spinal Cord | 1973 |
The mechanism of the antihypertensive action of -methyldopa in hypertensive rats.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Pressure; Desoxycorticosterone; Disulfiram; Hypertension; Male; Methyldopa; Monophenol Monooxygenase; Rats; Thiocarbamates; Time Factors | 1973 |
The effects of L-dopa and alpha-methyldopa on reflexes and sympathetic nerve function.
Topics: Animals; Atropine; Barbiturates; Benserazide; Blood Pressure; Carbidopa; Carotid Arteries; Dogs; Electric Stimulation; Heart Rate; Hindlimb; Levodopa; Methyldopa; Monoamine Oxidase Inhibitors; Neurons; Perfusion; Posture; Reflex; Regional Blood Flow; Sympathetic Nervous System; Vagotomy; Vagus Nerve | 1974 |
[Treatment of Parkinson's syndrome with L-dopa and its methylated derivatives: 3-OMD and 4-OMD associated with a decarboxylase inhibitor. Clinical and biochemical study].
Topics: Aged; Benserazide; Carboxy-Lyases; Depression; Dihydroxyphenylalanine; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrazines; Methyldopa; Middle Aged; Paralysis; Parkinson Disease; Sleep Wake Disorders; Time Factors | 1973 |
Dopa decarboxylase from visceral ganglion and gill of two lamellibranch mollusca as it relates to ciliary activity.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Carbon Radioisotopes; Carboxy-Lyases; Cilia; Dopa Decarboxylase; Electric Stimulation; Ganglia; Gills; In Vitro Techniques; Methyldopa; Mollusca; Serotonin; Time Factors; Tritium | 1973 |
[Research on the inhibitory action of several salicylic chalcones on the aromatic L-aminoacid-decarboxylase].
Topics: Alkenes; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Guinea Pigs; Ketones; Kidney; Methyldopa; Propiophenones; Salicylates; Structure-Activity Relationship | 1973 |
[Relationship between the antihypertensive activity of methyldopa and the appearance of its metabolites in the heart and brain of the hypertensive rat].
Topics: Animals; Antihypertensive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Biotransformation; Blood Pressure; Brain; Disulfides; Disulfiram; Dopamine; Dopamine beta-Hydroxylase; Hydrazines; Hypertension; Imidazoles; Male; Methane; Methyldopa; Myocardium; Norepinephrine; Rats; Sympatholytics; Time Factors; Tritium | 1974 |
[Catecholaminergic neuronal pathways in homeostatic control of blood circulating mass].
Topics: Adrenergic alpha-Antagonists; Animals; Benserazide; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Diuresis; Levodopa; Methyldopa; Phentolamine; Rats; Thirst | 1980 |
DOPA decarboxylase activity in the nervous system and the ctenidium of the freshwater clam, Musculium (Sphaerium) transversum.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Bivalvia; Carbidopa; Dopa Decarboxylase; Methyldopa; Nervous System; Respiratory System | 1984 |
Binding site of salsolinol: its properties in different regions of the brain and the pituitary gland of the rat.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Binding Sites; Binding, Competitive; Brain; Carbidopa; Clonidine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Enzyme Inhibitors; Female; Isoquinolines; Kinetics; Lactation; Levodopa; Male; Mazindol; Median Eminence; Methyldopa; Pituitary Gland; Pituitary Gland, Posterior; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Reserpine | 2003 |
Catechol-O-methyltransferase inhibition in erythrocytes and liver by BIA 3-202 (1-[3,4-dibydroxy-5-nitrophenyl]-2-phenyl-ethanone).
Topics: Acetophenones; Administration, Oral; Animals; Antiparkinson Agents; Benserazide; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Drug Interactions; Erythrocytes; Humans; In Vitro Techniques; Levodopa; Liver; Methylation; Methyldopa; Microdialysis; Rats; Rats, Wistar | 2003 |
The timing of administration, dose dependence and efficacy of dopa decarboxylase inhibitors on the reversal of motor disability produced by L-DOPA in the MPTP-treated common marmoset.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Callithrix; Carbidopa; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Enzyme Inhibitors; Female; Levodopa; Male; Methyldopa; Motor Activity; Movement Disorders | 2010 |
Simultaneous quantitation of levodopa and 3-O-methyldopa in human plasma by HPLC-ESI-MS/MS: application for a pharmacokinetic study with a levodopa/benserazide formulation.
Topics: Benserazide; Calibration; Chromatography, High Pressure Liquid; Humans; Levodopa; Methyldopa; Quality Control; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tablets; Tandem Mass Spectrometry | 2011 |