benserazide has been researched along with hydrazine in 230 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 218 (94.78) | 18.7374 |
| 1990's | 8 (3.48) | 18.2507 |
| 2000's | 1 (0.43) | 29.6817 |
| 2010's | 3 (1.30) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gerlach, J; Lühdorf, K | 1 |
| Chern, YF; Chow, CF; Lin, MT | 1 |
| Tyce, GM; Wong, KL | 2 |
| Birket-Smith, E; Dupont, E; Hansen, E; Hyyppä, M; Marttila, R; Mikkelsen, B; Pakkenberg, H; Presthus, J; Rinne, UK | 1 |
| Autret, A; Bussel, B; Castaigne, P; Cathala, HP; Minz, M | 1 |
| Ambrozi, L; Birkmayer, W; Riederer, P; Youdim, MB | 1 |
| Coxon, A; Greenacre, JK; Petrie, A; Reid, JL | 1 |
| Korf, J; Sebens, JB; van Wijk, M | 1 |
| Belliard, JP; Boismare, F; Hacpille, L; Le Poncin, M | 2 |
| Vellucci, SV | 1 |
| Collins, MA; Custod, JT; Rubenstein, JA; Tabakoff, B | 1 |
| Murphy, JA; Paparo, AA | 2 |
| Borri, P; Borri-Voltattorni, C; Minelli, A | 1 |
| Gilland, O | 1 |
| Castegnaro, E; Pontiroli, AE; Pozza, G; Vettaro, MP; Viberti, GC | 1 |
| Gierlichs, HW; Hawlina, A; Planz, G; Planz, R; Rahn, KH; Stephany, W | 1 |
| Battistin, L; Meneghetti, G; Rigotti, S; Saia, A | 1 |
| Annable, L; Chouinard, Q; Sourkes, TL; Young, SN | 1 |
| Diamond, SG; Markham, CH; Treciokas, LJ | 1 |
| Carlyle, D; Williams, BO | 1 |
| Del Pesce, M; Di Bella, P; Forastieri, L; Paggi, A; Quattrini, A | 1 |
| Martin, S | 1 |
| Hirayama, K; Kondo, T; Kuruma, I; Narabayashi, H; Yokochi, M | 2 |
| Birkmayer, W; Mentasti, M; Podiwinsky, F; Riederer, P | 1 |
| De Pasqua, A; Gala, RR; Girardi, AM; Pellicciotta, G; Pontiroli, AE; Pozza, G | 1 |
| Bender, DA; Earl, CJ; Lees, AJ | 1 |
| Barrionuevo, JA; Cabezas-Cerrato, J; Casanueva, F; Peñalva, A; Vila, T; Villanueva, L | 1 |
| Cassi, E; Massarotti, G; Passaleva, A | 1 |
| Carolei, A; Masturzo, P; Murialdo, G; Polleri, A; Toffano, G | 1 |
| Carolei, A; Masturzo, P; Murialdo, G; Polleri, A | 2 |
| Conte, P; Julien, J; Moulinier, J; Reiffers, J | 1 |
| Adlmici, G; Callea, L; Di Monda, V; Fazzari, G | 1 |
| Martignoni, E; Murialdo, G; Nappi, G; Polleri, A; Savoldi, F | 1 |
| Estey, E; Goldstein, M; Gopinathan, G; Lieberman, A; Ohashi, T; Sauter, A | 1 |
| Mölsä, P; Rinne, UK | 1 |
| Brandt, R; Schwartz, DE | 1 |
| Caraceni, TA; Celano, I; Girotti, F; Parati, E | 1 |
| Boismare, F; Boquet, J; Le Poncin, M; Lefrançois, J | 1 |
| Bender, DA; Hobbiger, F; Smith, WR | 1 |
| Combépine, C; Geissbühler, F; Hovaguimian, T; Raffin, Y; Streiff, U | 1 |
| Gallamini, A; Magnani, G; Masturzo, P; Murialdo, G; Nizzo, MC | 1 |
| Kuzuya, F; Mori, K; Sakamoto, N; Yoshimine, N | 1 |
| Gerlach, J | 1 |
| Avery, GS; Brogden, RN; Pinder, RM; Sawyer, PR; Speight, TM | 1 |
| Anabitarte, E; Mihatsch, M; Riede, UN; Schärer, K; Villiger, W | 1 |
| Chouza, C; Gomensoro, JB; Romero, S | 3 |
| Herishanu, Y; Rosenberg, P | 1 |
| Algeri, S; Campanella, G; Cerletti, C; Dolfini, E; Jori, A; Rinaldi, F | 1 |
| Annable, L; Charette, R; Chouinard, G; Serrano, M | 1 |
| Messiha, FS | 1 |
| Buu, NT; Kuchel, O; Parent, MT | 1 |
| Agid, Y; Lhermitte, F; Signoret, JL; Studler, JM | 1 |
| Bender, DA; Humm, RP; Smith, WR | 1 |
| Appel, JB; Carter, RB | 1 |
| Barbeau, A; Roy, M | 1 |
| Siegfried, J; Zumstein, H | 1 |
| Boismare, F; Hacpille, L; Le Poncin, M | 1 |
| Goodwin, BL; Johnson, RD; Ruthven, CR; Sandler, M | 1 |
| Bass-Verrey, F; Ludin, HP | 1 |
| Goodale, DB; Moore, KE | 1 |
| Augier, D; Dutau, G; Enjaume, P; Ribot, C; Rochiccioli, P | 1 |
| Mizuno, Y; Obayashi, T; Ueki, A; Yoshida, M | 1 |
| Geissbühler, F; Widmer, J | 1 |
| Tyce, GM | 1 |
| Kato, N; Murase, Y | 1 |
| Aghajanian, GK; Gallager, DW | 1 |
| Korf, J; Lequin, RM; van Praag, HM | 1 |
| Gabreëls, FJ; Joosten, EM; Keyser, A; Korten, JJ | 1 |
| Boismare, F; Boquet, J | 1 |
| Birket-Smith, E | 1 |
| Stern, M; Stern, VP | 1 |
| Rinne, UK; Siirtola, T; Sonninen, V | 2 |
| Constantinidis, J; Gaillard, JM; Tissot, R | 1 |
| Aldor, T; Gilat, T; Kesten, M; Loewenthal, M; Streifler, M | 1 |
| Birket-Smith, E; Dupont, E; Hansen, E; Mikkelsen, B; Pakkenberg, H; Presthus, J; Rautakorpi, I; Riman, E; Rinne, UK | 1 |
| Burke, RE; Reches, A | 1 |
| Reinhard, JF; Shearin, MD | 1 |
| Ceballos-Baumann, AO; Eckert, W; von Kummer, R; Weicker, H | 1 |
| Blackburn, NA; Boddie, HG; Ellis, CJ; Kendal, BR; MacMahon, DG; Sachdev, D | 1 |
| Berger, HJ; Horstink, MW; Pasman, JW; van't Hof, MA; Zijlmans, JC | 1 |
| Allievi, C; Bellotti, V; Benedetti, MS; Dordain, G; Dostert, P | 1 |
| Aslanian, V; Lambas-Senas, L; Renaud, B | 1 |
| Kraus, P; Kuhn, W; Przuntek, H | 1 |
| Miñano, FJ; Myers, RD | 1 |
| Rammsayer, T | 1 |
| Rinne, JO; Rinne, UK | 1 |
| Dordain, G; Dostert, P; Strolin Benedetti, M; Vernay, D | 1 |
| Campanella, G; De Michele, G; Filla, A; Mengano, A; Trombetta, L | 1 |
| Liu, DK | 3 |
| Caraceni, T; Lamperti, E; Lorizio, A; Nordera, N | 1 |
| Dichgans, J; Scholz, E | 1 |
| Chudakova, IV; Hiripi, L; Rózsa, KS | 1 |
| Albani, C; Hacisalihzade, SS; Mansour, M | 1 |
| Cossutta, E; Ferrante, C; Pezzoli, G; Scarlato, G; Tesei, S; Zecchinelli, A | 2 |
| Aljanati, R; Caamaño, JL; Chouza, C; de Medina, O; Romero, S; Scaramelli, A | 1 |
| Dupont, E; Hansen, E; Jensen, NO; Mikkelsen, B; Mikkelsen, BO | 2 |
| Stern, G | 1 |
| Mondal, BK; Mondal, KN | 1 |
| Birkmayer, GD; Birkmayer, W | 1 |
| Csanda, E; Takáts, A; Tárczy, M | 1 |
| Da Prada, M; Haefely, WE; Kettler, R; Schaffner, R; Zürcher, G | 1 |
| Kuhn, W; Przuntek, H | 1 |
| Bayer, AJ; Day, JJ; Finucane, P; Pathy, MS | 1 |
| Rabin, RA; Winter, JC | 1 |
| Battegay, R; Gastpar, M; Zmilacher, K | 1 |
| Marion, MH; Marsden, CD; Quinn, NP | 1 |
| Aymard, N; Holzer, J; Rondot, P; Ziegler, M | 2 |
| Erni, W; Held, K | 1 |
| Jenner, P; Malcolm, SL; Marion, MH; Marsden, CD; Quinn, NP; Stocchi, F | 1 |
| Ludin, HP | 1 |
| D'Andrea, G; Durisotti, C; Ferro-Milone, F; Lion, P; Lorizio, A; Nordera, GP | 1 |
| Baas, H; Fischer, PA | 1 |
| Heersema, T; Jansen, EN; Meerwaldt, JD; Speelman, JD; van Manen, J | 1 |
| Lees, AJ; Poewe, WH; Stern, GM | 1 |
| Jansen, EN; Meerwaldt, JD | 1 |
| Rinne, UK | 1 |
| Lees, AJ | 1 |
| Allen, JG; Bird, H; Malcolm, SL; Marion, MH; Marsden, CD; O'Leary, CG; Quinn, NP | 1 |
| Crevoisier, C; Da Prada, M; Hoevels, B; Zürcher, G | 1 |
| Aljanati, R; Caamano, JL; Chouza, C; de Medina, O; Gonzales Panizza, V; Romero, S; Scarmelli, A | 1 |
| Siegfried, J | 1 |
| Aizenstadt, TB; Chudakova, IV; Rózsa, KS | 1 |
| Jenner, P; Marion, MH; Marsden, CD; Quinn, NP; Stocchi, F | 1 |
| Birkmayer, W; Hars, V; Knoll, J; Marton, J; Riederer, P; Youdim, MB | 1 |
| Berglund, B; Kaijser, L; Sachs, C | 1 |
| Azevedo, M; Coelho, H; Manso, C | 1 |
| Bonura, ML; De Maria, A; Masturzo, P; Murialdo, G; Polleri, A; Zauli, C | 1 |
| Kawai, K; Kitamura, J; Mori, H; Sugie, S | 1 |
| Domenici, L; Fiorentini, A; Maffei, L; Piccolino, M; Trimarchi, C | 1 |
| Yu, HZ | 1 |
| Clark, WG; Dewherst, WG; Oldendorf, WH | 1 |
| Gardey-Levassort, C; Lechat, P | 1 |
| Carlsson, A | 1 |
| Bakke, OM; Scheline, RR | 1 |
| Benkert, O; Matussek, N; Renz, A | 1 |
| Krip, G; Vazquez, AJ | 1 |
| Candelise, L; Faglioni, P; Spinnler, H; Vignolo, LA | 1 |
| Birkmayer, W; Linauer, W; Mentasti, M; Riederer, P | 1 |
| Randall, W; Trulson, M | 1 |
| Minsker, DH; Stokes, AL | 1 |
| Rondot, P | 1 |
| de la Garza, R; Ivan-Reynoso, G; Lombardo, L | 1 |
| Balestreri, R; Bertolini, S; Costa, S; Elicio, N | 1 |
| Baumann, N; Castaigne, P; Rondot, P; Taberlet, A | 1 |
| Campanella, G; Pennetta, R | 1 |
| Masi, G; Megna, GF; Puca, FM; Specchio, LM | 1 |
| Boggan, WO; Seiden, LS | 1 |
| Carruba, M; Da Prada, M; O'Brien, A; Pletscher, A; Saner, A | 1 |
| Itokawa, Y; Takaori, S; Tanaka, C; Tanaka, S | 1 |
| Gardey-Levassort, C; Lechat, P; Olive, G | 1 |
| Bocknik, SE; Kulkarni, AS | 1 |
| Buser, P; Viala, D | 1 |
| Steinhäusl, H | 1 |
| Dietrichson, P | 1 |
| Eisenlohr, JJ; Gehlen, W | 1 |
| Angst, J; Benkert, O; Gmür, M; Matussek, N; Papousek, M; Rüther, E; Woggon, B | 1 |
| Friedman, E; Gershon, S | 1 |
| Kesten, M; Streifler, M; Vardi, J | 1 |
| Bartholini, G; Constantinidis, J; de Ajuriaguerra, J; Eisenring, JJ; Geissbühler, F; Tissot, R; Yanniotis, G | 1 |
| Cavagnini, F; Malinverni, A; Peracchi, M; Pontiroli, AE; Raggi, U | 1 |
| Van Wieringen, A | 1 |
| Cohen, Y; Jacquot, C; Rapin, J; Wepierre, J | 1 |
| Maj, J; Pawlowski, L; Sarnek, J | 1 |
| Jordan, JC; Schwartz, DE; Ziegler, WH | 1 |
| Fujimori, N; Itoga, E; Kito, S; Kosaka, K; Yamamoto, M | 1 |
| Barbeau, A; Gillo-Joffroy, L; Mars, H | 1 |
| Casey, DE; Gerlach, J | 1 |
| Achilli, G; Algeri, S; Cimino, M; Lipartiti, M; Perego, C; Ponzio, F; Vantini, G | 1 |
| Beretta, E; de Crousaz, G; Regli, F; Steck, AJ | 1 |
| Buda, M; Cespuglio, R; Faradji, H; Gonon, F; Jouvet, M; Pujol, JF; Riou, F | 1 |
| Magnussen, I; Van Woert, MH | 1 |
| Chiang, CY; Ory-Lavollee, L; Rivot, JP | 1 |
| Trouillas, P | 1 |
| Iadgarov, IS; Kandel', EI | 1 |
| Nikolić, J; Stepanović, SR | 1 |
| Bender, DA | 1 |
| Bondiolotti, GP; Cocchi, D; Locatelli, V; Müller, EE; Parati, EA; Parenti, M; Penalva, A; Picotti, GB | 1 |
| Goldstein, M; Gopinathan, G; Hiesiger, E; Lieberman, AN; Nelson, J; Neophytides, A; Walker, R | 1 |
| King, TS; Reiter, RJ; Steger, RW; Steinlechner, S | 1 |
| Ho, AK; Smith, JA | 2 |
| Gerdes, U; Lehmann, K; Ulm, G | 1 |
| Hsu, LL | 1 |
| Kamenetskiĭ, VK | 1 |
| Curzon, G; Drewitt, PN; Tricklebank, MD | 1 |
| Anderson, GM; Chouinard, G; Gauthier, S; Purdy, WC; Young, SN | 1 |
| Dean, BC; McLellan, DL | 1 |
| Caraceni, T; Cocchi, D; Giovannini, P; Martinez-Campos, A; Müller, EE; Novelli, A | 1 |
| Juorio, AV | 1 |
| Geller, I; Hartmann, RJ; Messiha, FS | 1 |
| Adeleine, P; Bard, J; Brudon, F; Garde, A; Renaud, B; Robert, JM; Trouillas, P | 1 |
| Klingler, M | 1 |
| Agnoli, A; Baldassarre, M; D'Urso, R; De Giorgio, G; Falaschi, P; Rocco, A; Ruggieri, S | 1 |
| Andree, TH; Clarke, DE | 1 |
| Passerini, D; Pezzoli, G; Radaelli, F; Scarlato, G | 1 |
| Callingham, BA; Lyles, GA | 2 |
| Akpinar, S | 1 |
| Falsetti, L; Loda, G; Pontiroli, AE; Roggia, A; Scagliola, P | 1 |
| de Vries, T; Garbis-Berkvens, JM; Peters, PW; Rauws, AG; van Logten, MJ; Vos, JG | 1 |
| Arendt, J; Ho, AK; Laud, C; Marston, A; Nohria, V; Smith, JA; Symons, AM | 1 |
| Chan, LL; Sinniah, D | 1 |
| Giorgi, O; Rubio, MC | 1 |
| Pogson, CI; Smith, SA | 1 |
| Alberetto, M; de Pasqua, A; Falsetti, L; Girardi, AM; Pellicciotta, G; Pontiroli, AE; Pozza, G; Voltolini, AM | 1 |
| Caraceni, T; Giovannini, P; Martinez-Campos, A; Müller, EE; Novelli, A; Parati, E | 1 |
| Delitala, G; Devilla, L; Lotti, G | 1 |
| Gulliver, PA; Hagan, RM; Raxworthy, MJ | 1 |
| Delitala, G; Devilla, L; Pende, A | 1 |
| Lambás-Señas, L; Ortemann, C; Pujol, JF; Renaud, B; Robert, F | 1 |
| Beiske, A; Fotteler, B; Jorga, KM; Larsen, JP; Moe, B; Schleimer, M; Schmitt, M | 1 |
| Funabashi, T; Goshima, Y; Kimura, F; Kuroiwa, Y; Misu, Y; Shimamura, M; Shimizu, M; Yagami, T | 1 |
| Alachkar, A; Brotchie, JM; Jones, OT | 1 |
| Abe, H; Ebihara, K; Ikarashi, Y; Imamura, S; Ishida, Y; Kase, Y; Koganemaru, G; Mizoguchi, K; Sekiguchi, K; Tabuchi, M | 1 |
| Du, N; Guo, Z; Han, M; Huang, Y; Liu, J; Xu, S | 1 |
4 review(s) available for benserazide and hydrazine
| Article | Year |
|---|---|
Levodopa and decarboxylase inhibitors: a review of their clinical pharmacology and use in the treatment of parkinsonism.
Topics: Benserazide; Binding Sites; Carbidopa; Carboxy-Lyases; Drug Interactions; Humans; Hydrazines; Kinetics; Levodopa; Liver Function Tests; Parkinson Disease | 1976 |
The hydrodynamically balanced system: a novel principle of controlled drug release.
Topics: Administration, Oral; Benserazide; Biological Availability; Capsules; Delayed-Action Preparations; Drug Combinations; Humans; Hydrazines; Levodopa | 1987 |
Measurements of monoamine synthesis and turnover with special reference to 5-hydroxytryptamine.
Topics: Acetamides; Animals; Benserazide; Benzyl Compounds; Biogenic Amines; Brain; Carboxy-Lyases; Dibenzazepines; Dihydroxyphenylalanine; Feedback; Hydrazines; Hypoxia; Kinetics; Lysergic Acid Diethylamide; Methyltyrosines; N,N-Dimethyltryptamine; Neural Conduction; Pargyline; Rats; Reserpine; Serotonin; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 1974 |
[Decarboxylase inhibitor given in combination with l-dopa. A new therapeutic principal in parkinsonism].
Topics: Administration, Oral; Animals; Benserazide; Dihydroxyphenylalanine; Drug Therapy, Combination; Humans; Hydrazines; Parkinson Disease; Time Factors | 1973 |
44 trial(s) available for benserazide and hydrazine
| Article | Year |
|---|---|
The effect of L-dopa on young patients with simple schizophrenia, treated with neuroleptic drugs: a double-blind cross-over trial with Madopar and placebo.
Topics: Adult; Affect; Antipsychotic Agents; Anxiety; Basal Ganglia Diseases; Benserazide; Brief Psychiatric Rating Scale; Clinical Trials as Topic; Drug Combinations; Emotions; Humans; Hydrazines; Levodopa; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Social Behavior | 1975 |
Levodopa alone and in combination with a peripheral decarboxylase inhibitor benserazide (Madopar) in the treatment of Parkinson's disease: A controlled clinical trial.
Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Nausea; Parkinson Disease; Vomiting | 1975 |
Implications of combined treatment with 'Madopar' and L-deprenil in Parkinson's disease. A long-term study.
Topics: Administration, Oral; Aged; Benserazide; Clinical Trials as Topic; Disability Evaluation; Drug Combinations; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrazines; Injections, Intravenous; Levodopa; Male; Monoamine Oxidase Inhibitors; Parkinson Disease; Phenethylamines; Time Factors | 1977 |
Comparison of levodopa with carbidopa or benserazide in parkinsonism.
Topics: Aged; Benserazide; Carbidopa; Consumer Behavior; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
[Levodopa and decarboxylase inhibitors in Parkinson's disease].
Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Nausea; Parkinson Disease; Vomiting | 1977 |
Stimulatory effect of the dopa-decarboxylase inhibitor Ro 4-4602 on prolactin release; inhibition by l-dopa, metergoline, methysergide and 2-Br-alpha-ergocryptine.
Topics: Administration, Oral; Adolescent; Adult; Benserazide; Bromocriptine; Clinical Trials as Topic; Drug Interactions; Ergolines; Female; Humans; Hydrazines; Levodopa; Male; Metergoline; Methysergide; Middle Aged; Pituitary Gland; Pituitary Gland, Anterior; Prolactin; Secretory Rate; Stimulation, Chemical; Time Factors | 1977 |
Influence of the decarboxylase inhibitor benserazide on the antihypertensive effect and metabolism of alpha-methyldopa in patients with essential hypertension.
Topics: Adult; Benserazide; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Female; Humans; Hydrazines; Hypertension; Male; Methyldopa; Middle Aged; Placebos | 1977 |
Long-term treatment of Parkinson's disease with L-Dopa and Dopa-decarboxylase inhibitor: therapeutic results and side effects.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1978 |
A controlled study of tryptophan-benserazide in schizophrenia.
Topics: Adult; Aged; Benserazide; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrazines; Kynurenine; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Tryptophan | 1978 |
A double-blind comparison of levodopa, Madopa, and Sinemet in Parkinson disease.
Topics: Adult; Benserazide; Carbidopa; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Nausea; Parkinson Disease; Vomiting | 1978 |
Levodopa/benserazide ('Madopar') combination therapy in elderly patients with parkinsonism.
Topics: Activities of Daily Living; Aged; Benserazide; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1979 |
[Efficacy and side-effects of long term L-dopa therapy in Parkinsonian syndromes (evaluated by CT scan as well) (author's transl)].
Topics: Adult; Benserazide; Brain; Carbidopa; Clinical Trials as Topic; Confusion; Electrocardiography; Electroencephalography; Female; Humans; Hydrazines; Hyperkinesis; Levodopa; Male; Middle Aged; Parkinson Disease, Secondary; Stomach Diseases; Tomography, X-Ray Computed | 1979 |
[The combined treatment of Parkinson's disease with L-dopa plus decarboxylase inhibitors (carbidopa, benserazide) (author's transl)].
Topics: Aged; Benserazide; Carbidopa; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1979 |
Levodopa with benserazide or carbidopa in Parkinson disease.
Topics: Benserazide; Biological Availability; Carbidopa; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1979 |
Effect of CB 154 (2-bromo-alpha-ergocryptine) on paralysis agitans compared with Madopar in a double-blind, cross-over trial.
Topics: Aged; Azides; Benserazide; Bromocriptine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Ergolines; Female; Humans; Hydrazines; Hyperkinesis; Levodopa; Male; Middle Aged; Nausea; Parkinson Disease; Psychoses, Substance-Induced | 1976 |
A controlled study of a dopa decarboxylase inhibitor (benserazide) in the treatment of schizophrenic patients.
Topics: Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Chlorpromazine; Female; Humans; Hydrazines; Male; Middle Aged; Psychotropic Drugs; Schizophrenia | 1977 |
Madopar versus sinemet. A clinical study on their effectiveness.
Topics: Adult; Aged; Benserazide; Carbidopa; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Serine | 1975 |
Parkinson's disease treated with Sinemet or Madopar. A controlled multicenter trial.
Topics: Aged; Benserazide; Carbidopa; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
Controlled-release levodopa/benserazide (Madopar HBS): clinical observations and levodopa and dopamine plasma concentrations in fluctuating parkinsonian patients.
Topics: Aged; Benserazide; Carboxy-Lyases; Clinical Trials as Topic; Delayed-Action Preparations; Dopamine; Drug Combinations; Female; Follow-Up Studies; Hospitalization; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1990 |
A comparison of the effects of controlled-release levodopa (Madopar CR) with conventional levodopa in late Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Benserazide; Carboxy-Lyases; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Motor Skills; Multicenter Studies as Topic; Neurologic Examination; Parkinson Disease | 1990 |
Is there a common dopaminergic basis of time perception and reaction time?
Topics: Adult; Benserazide; Brain; Clinical Trials as Topic; Dopamine Agents; Double-Blind Method; Drug Combinations; Haloperidol; Humans; Hydrazines; Levodopa; Male; Reaction Time; Receptors, Dopamine; Time Perception | 1989 |
A comparison of Madopar CR and standard Madopar in the treatment of nocturnal and early-morning disability in Parkinson's disease. The U.K. Madopar CR Study Group.
Topics: Activities of Daily Living; Aged; Benserazide; Circadian Rhythm; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Parkinson Disease; Randomized Controlled Trials as Topic | 1989 |
A double-blind, cross-over trial with madopar HBS in patients with Parkinson's disease.
Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease, Secondary | 1989 |
A combined regimen of subcutaneous lisuride and oral Madopar HBS in Parkinson's disease.
Topics: Administration, Oral; Benserazide; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Drug Tolerance; Ergolines; Humans; Hydrazines; Infusion Pumps; Levodopa; Lisuride; Parkinson Disease; Severity of Illness Index | 1988 |
A controlled release form of madopar in parkinsonian patients with advanced disease and marked fluctuations in motor performance.
Topics: Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Drug Administration Schedule; Drug Combinations; Humans; Hydrazines; Levodopa; Middle Aged; Movement; Parkinson Disease | 1988 |
Madopar HBS in fluctuating parkinsonian patients: two-year treatment.
Topics: Adult; Aged; Benserazide; Carboxy-Lyases; Clinical Trials as Topic; Delayed-Action Preparations; Drug Administration Schedule; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1988 |
The effect of R-(-)-deprenyl in de novo Parkinson patients on combination therapy with levodopa and decarboxylase inhibitor.
Topics: Benserazide; Clinical Trials as Topic; Disability Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement; Parkinson Disease; Phenethylamines; Selegiline | 1987 |
Bioavailability and acceptability of a dispersible formulation of levodopa-benserazide in parkinsonian patients with and without dysphagia.
Topics: Aged; Aged, 80 and over; Benserazide; Biological Availability; Capsules; Consumer Behavior; Deglutition Disorders; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease, Secondary; Random Allocation; Tablets | 1988 |
Open study of Madopar HBS, a new formulation of levodopa with benserazide, in 13 patients with Parkinson's disease and 'on-off' fluctuations.
Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Clinical trial of Madopar HBS in parkinsonian patients with fluctuating drug response after long-term levodopa therapy.
Topics: Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Time Factors | 1987 |
Single-dose studies of a slow-release preparation of levodopa and benserazide (Madopar HBS) in Parkinson's disease.
Topics: Administration, Oral; Adult; Aged; Benserazide; Biological Availability; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease; Random Allocation | 1987 |
Open clinical study of Madopar HBS.
Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Infant, Newborn; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Treatment of parkinsonian conditions with a controlled-release form of levodopa--preliminary study.
Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Preliminary experience with Madopar HBS: clinical observations and plasma levodopa concentrations.
Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Female; Follow-Up Studies; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Open multicenter trial with Madopar HBS in parkinsonian patients. Preliminary assessment after short-term treatment.
Topics: Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Time Factors | 1987 |
Clinical and pharmacokinetic observations with Madopar HBS in hospitalized patients with Parkinson's disease and motor fluctuations.
Topics: Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Hospitalization; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
[Controlled release levodopa-benserazide and changes in efficacy during treatment of Parkinson's disease].
Topics: Adult; Aged; Benserazide; Carboxy-Lyases; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1987 |
Single-dose study of slow release preparation of levodopa and benserazide (Madopar HBS) in Parkinson's disease.
Topics: Administration, Oral; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Disability Evaluation; Drug Combinations; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease; Random Allocation | 1987 |
Letter: Treatment of Huntington's chorea.
Topics: Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Clinical Trials as Topic; Diazepam; Dihydroxyphenylalanine; Drug Therapy, Combination; Haloperidol; Humans; Huntington Disease; Hydrazines; Reserpine | 1973 |
[2-year experiences with a combination treatment of Parkinsonism with L-dopa and a decarboxylase inhibitor (Benserazid, Ro 4-4602)].
Topics: Benserazide; Carboxy-Lyases; Clinical Trials as Topic; Dermatitis, Seborrheic; Dihydroxyphenylalanine; Drug Combinations; Drug Evaluation; Humans; Hydrazines; Movement Disorders; Muscle Rigidity; Parkinson Disease; Speech Disorders; Tremor | 1974 |
[Experiences in the treatment of Parkinson's disease with a combination drug: L-dopa plus decarboxylase inhibitor (Ro 8-0576)].
Topics: Benserazide; Carboxy-Lyases; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Combinations; Evaluation Studies as Topic; Gastrointestinal Diseases; Gymnastics; Humans; Hydrazines; Levodopa; Parkinson Disease; Speech Therapy | 1973 |
The effect of L-5-hydroxytryptophan alone and in combination with a decarboxylase inhibitor (Ro-4-4602) in depressive patients.
Topics: Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Clinical Trials as Topic; Depression; Drug Therapy, Combination; Female; Humans; Hydrazines; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Serotonin; Time Factors | 1974 |
Report on 45-month treatment of parkinsonism with L-dopa, alone and in association with a decarboxilase inhibitor (Ro 4-4602).
Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Tablets | 1974 |
The effect of tolcapone on the pharmacokinetics of benserazide.
Topics: Aged; Antiparkinson Agents; Benserazide; Benzophenones; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Nitrophenols; Parkinson Disease; Time Factors; Tolcapone; Tyrosine | 1999 |
182 other study(ies) available for benserazide and hydrazine
| Article | Year |
|---|---|
The effects of a decarboxylase inhibitor, benserazide, on both thermoregulation and chlorpromazine-induced hypothermia in rats.
Topics: Animals; Benserazide; Body Temperature; Body Temperature Regulation; Brain Chemistry; Chlorpromazine; Hydrazines; Male; Rats; Serotonin; Time Factors | 1978 |
Pyridoxal 5'-phosphate levels in brain after treatments which impair cerebral glucose metabolism.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Benserazide; Brain; Cyclopropanes; Glucose; Hepatectomy; Hydrazines; Levodopa; Male; Monoamine Oxidase Inhibitors; Phenyl Ethers; Pyridoxal Phosphate; Rats | 1979 |
Human sleep and 5-HTP. Effects of repeated high doses and of association with benserazide (RO.04.4602).
Topics: 5-Hydroxytryptophan; Adult; Benserazide; Drug Combinations; Electroencephalography; Humans; Hydrazines; Male; Mental Processes; Sleep Stages | 1976 |
Probenecid-induced increase of 5-hydroxytryptamine synthesis in rat brain, as measured by formation of 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Blood-Brain Barrier; Brain; Brain Chemistry; Hydrazines; Hydroxyindoleacetic Acid; Hydroxylation; Male; Probenecid; Rats; Serotonin; Stimulation, Chemical; Time Factors; Tryptophan | 1979 |
[Effect of L-dopa combined with benserazide on hemodynamics and motor activity in hypoxic rats].
Topics: Animals; Benserazide; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Female; Heart Rate; Hemodynamics; Hydrazines; Hypoxia; Levodopa; Motor Activity; Oxygen; Rats | 1975 |
The effects of a high dose of benserazide on the concentrations of 5-hydroxytryptamine, noradrenaline and dopamine in different regions of the rat brain.
Topics: Animals; Benserazide; Brain Chemistry; Dopamine; Fenclonine; Hydrazines; Male; Methyltyrosines; Norepinephrine; Rats; Serotonin | 1978 |
Studies on the effects of pyrogallol and the structurally related dopa decarboxylase inhibitor RO4-4602 on acetaldehyde metabolism.
Topics: Acetaldehyde; Alcoholism; Aldehyde Oxidoreductases; Animals; Benserazide; Chloral Hydrate; Ditiocarb; Ethanol; Humans; Hydrazines; In Vitro Techniques; Liver; Pyrogallol; Rats | 1976 |
The effect of STH on the SEM and frequency response of the branchial nerve in Mytilus edulis as it relates to ciliary activity.
Topics: Benserazide; Bivalvia; Branchial Region; Cilia; Ganglia; Hydrazines; Microscopy, Electron, Scanning; Muscles; Time Factors | 1975 |
The effect of STH and 6-OH-dopa on the SEM of the branchial nerve and visceral ganglion of the bivalve Elliptio complanata as it relates to ciliary activity.
Topics: Benserazide; Bivalvia; Branchial Region; Cilia; Dihydroxyphenylalanine; Electric Stimulation; Ganglia; Hydrazines; Microscopy, Electron, Scanning; Time Factors | 1975 |
Interaction of N-(DL-seryl)N'-(2,3,4-trihydroxybenzyl)-hydrazine with L-dopa decarboxylase from pig kidney.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Dopa Decarboxylase; Hydrazines; Kidney; Kinetics; Levodopa; Protein Binding; Spectrophotometry; Spectrophotometry, Ultraviolet; Swine; Tyrosine | 1977 |
Effect of administration of 5-hydroxytryptophan and an inhibitor of L-aromatic amino acid decarboxylase on glucose metabolism in rat brain.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Benserazide; Blood Glucose; Brain; Brain Chemistry; Glucose; Glutamates; Hydrazines; Male; Rats; Serotonin | 1979 |
Pharmaceutical review: salbutamol - madopar - isocal.
Topics: Albuterol; Australia; Benserazide; Humans; Hydrazines; Levodopa; Lung Diseases; Parenteral Nutrition; Parkinson Disease | 1978 |
[Comparative studies of L-DOPA alone and combination with a peripheral DOPA decarboxylase inhibitor, HCL-benserazide, on Parkinson's disease-part I: clinical aspects (author's transl)].
Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Pressure; Dopa Decarboxylase; Drug Administration Schedule; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1979 |
[Comparative studies of L-DOPA alone and combination with a peripheral DOPA decarboxylase inhibitor, benserazide-HCl, on Parkinson's disease--Part II: Pharmacokinetic study (author's transl)].
Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Drug Therapy, Combination; Female; Humans; Hydrazines; Kinetics; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1979 |
Study on the reproducibility of human prolactin response to sulpiride, benserazide, insulin hypoglycaemia and arginine infusion.
Topics: Adult; Arginine; Benserazide; Evaluation Studies as Topic; Female; Humans; Hydrazines; Insulin; Male; Middle Aged; Prolactin; Sulpiride | 1979 |
Niacin depletion in Parkinsonian patients treated with L-dopa, benserazide and carbidopa.
Topics: Adolescent; Adult; Benserazide; Bromocriptine; Carbidopa; Female; Humans; Hydrazines; Levodopa; Male; Micrococcus; Middle Aged; Nicotinamidase; Nicotinic Acids; Parkinson Disease; Tryptophan | 1979 |
[Growth hormone secretion induced by L-Dopa and a dopa decarboxylase inhibitor blocked by free fatty acids].
Topics: Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Drug Synergism; Fatty Acids, Nonesterified; Female; Growth Hormone; Humans; Hydrazines; Levodopa; Male; Pituitary Gland; Secretory Rate | 1979 |
Lupus-like autoimmune syndrome after levodopa and benserazide.
Topics: Autoimmune Diseases; Benserazide; Humans; Hydrazines; Levodopa; Lupus Erythematosus, Systemic; Male; Middle Aged; Syndrome | 1979 |
Lack of counteracting effect of liposomes on benserazide-induced hyperprolactinemia.
Topics: Adult; Animals; Benserazide; Brain Chemistry; Cattle; Female; Humans; Hydrazines; Liposomes; Male; Phospholipids; Prolactin | 1979 |
Dose and sex related effects of benserazide on prolactin secretion.
Topics: Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Dose-Response Relationship, Drug; Female; Humans; Hydrazines; Male; Prolactin; Sex Characteristics | 1979 |
["Immune type" haemolysis in course of L. dopa-benserazide therapeutic (author's transl)].
Topics: Aged; Anemia, Hemolytic, Autoimmune; Benserazide; Coombs Test; Female; Humans; Hydrazines; Levodopa; Parkinson Disease | 1979 |
[On a muscular dystony case from manganism. Therapeutic clinic considerations (author's transl)].
Topics: Benserazide; Diazepam; Dystonia; Haloperidol; Humans; Hydrazines; Levodopa; Male; Manganese; Middle Aged | 1979 |
Benserazide induces migraine attacks. Irrelevance of concomitant hyperprolactinemia.
Topics: Adult; Benserazide; Female; Humans; Hydrazines; Migraine Disorders; Prolactin; Sulpiride | 1979 |
Comparative effectiveness of two extracerebral DOPA decarboxylase inhibitors in Parkinson disease.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Dihydroxyphenylalanine; Female; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease | 1978 |
Pharmacokinetic and metabolic studies of the decarboxylase inhibitor benserazide in animals and man.
Topics: Animals; Benserazide; Dogs; Drug Stability; Humans; Hydrazines; Intestinal Absorption; Kinetics; Male; Rats; Species Specificity; Tissue Distribution | 1978 |
Bromocriptine alone or associated with L-dopa plus benserazide in Parkinson's disease.
Topics: Aged; Benserazide; Bromocriptine; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1977 |
[Improvement with the combination of L-dopa and benserazide of postural dysregulations of the cerebral circulation: preliminary study].
Topics: Benserazide; Cerebrovascular Circulation; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypotension, Orthostatic; Levodopa; Male; Posture | 1977 |
Benserazide effects on tryptophan metabolism in mice [proceedings].
Topics: Animals; Benserazide; Hydrazines; Mice; Tryptophan | 1978 |
[Endogenous 3-O-methyldopa in man: normal level and effect of an inhibitor of aromatic amino-acid decarboxylase (Benserazid) (author's transl)].
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Humans; Hydrazines; Methyldopa; Spectrometry, Fluorescence | 1978 |
[Effects of benserazide administration on prolactin secretion].
Topics: Acromegaly; Adult; Benserazide; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Pituitary Gland, Anterior; Prolactin | 1978 |
[Effect of VB6 on L-DOPA decarboxylase activity in the organs of rats given peripheral L-DOPA decarboxylase inhibitors (author's transl)].
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Dopa Decarboxylase; Hydrazines; Levodopa; Male; Pyridoxine; Rats | 1978 |
[Ultrastructural studies on an animal model of epiphyseolysis. Cells and matrix in the proximal growth plate of the rat tibia after administration of DL-serine(3,4,5-trihydroxybenzyl)-hydrazide] (author's transl)
Topics: Animals; Benserazide; Cartilage; Cell Division; Endoplasmic Reticulum; Epiphyses, Slipped; Hydrazines; Male; Microscopy, Electron; Ossification, Heterotopic; Rats; Tibia | 1975 |
[Long-term syndrome in the treatment of parkinsonism with L-dopa and decarboxylase an inhibitor].
Topics: Adult; Benserazide; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Long-Term Care; Male; Middle Aged; Parkinson Disease | 1976 |
Effect of L-dopa on polycythemia.
Topics: Aged; Benserazide; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Polycythemia Vera | 1977 |
Correlation of clinical symptoms, HVA and 5-HIAA in csf and plasma L-DOPA in Parkinsonian patients treated with L-DOPA and L-DOPA + RO 4-4602.
Topics: Benserazide; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Time Factors | 1977 |
Possible mechanism of adverse reaction following levodopa plus benserazide treatment.
Topics: Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Animals; Benserazide; Drug Interactions; Hydrazines; Levodopa; Liver; Male; Rats; Time Factors | 1977 |
Competitive inhibition of catechol O-methyltransferase by RO-4-4602.
Topics: Animals; Benserazide; Binding, Competitive; Catechol O-Methyltransferase Inhibitors; Hydrazines; Kinetics; Liver; Norepinephrine; Rats | 1977 |
["Beginning and end of dose" dyskinesias caused by L-DOPA].
Topics: Benserazide; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1977 |
Effects of benserazide on tryptophan metabolism in the mouse.
Topics: Animals; Benserazide; Carbon Dioxide; Hydrazines; Hydrolases; In Vitro Techniques; Kynurenic Acid; Kynurenine; Liver; Mice; Mice, Inbred Strains; Time Factors; Transaminases; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1977 |
Blockade of the behavioral effects of 5-HTP by the decarboxylase inhibitor Ro 4-4602.
Topics: Animals; Behavior, Animal; Benserazide; Conditioning, Operant; Hydrazines; Male; Rats; Serotonin Antagonists; Time Factors | 1976 |
Six-year results of treatment with levodopa plus benzerazide in Parkinson's disease.
Topics: Adult; Aged; Benserazide; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Patient Dropouts; Time Factors | 1976 |
Mortality among Parkinson patients treated with L-dopa combined with a decarboxylase inhibitor.
Topics: Adult; Aged; Benserazide; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Retrospective Studies; Switzerland | 1976 |
Cardiovascular responses to acute hypoxia in dogs pretreated with benserazide and L-DOPA.
Topics: Animals; Benserazide; Blood Gas Analysis; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Hemodynamics; Hydrazines; Hypoxia; Levodopa; Regional Blood Flow; Respiration; Vascular Resistance | 1976 |
In vivo assessment of decarboxylase inhibition or potentiation: urinary dopamine and L-dopa output after L-dopa administration.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Dopamine; Drug Interactions; Humans; Hydrazines; Levodopa; Parkinson Disease; Pyridoxine; Rats | 1976 |
Study of deterioration in long-term treatment of parkinsonism with L-dopa plus decarboxylase inhibitor.
Topics: Benserazide; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1976 |
A comparison of the effects of decarboxylase inhibitors on L-dopa-induced circling behavior and the conversion of dopa to dopamine in the brain.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Benserazide; Brain; Brocresine; Carbidopa; Dopamine; Hydrazines; Levodopa; Male; Methyldopa; Rats; Time Factors | 1976 |
[Attempt at potentiation of the action of L-dopa on the secretion of growth hormone by benserazide, disulfiram and propranolol].
Topics: Adolescent; Benserazide; Child; Disulfiram; Drug Synergism; Growth Hormone; Humans; Hydrazines; Levodopa; Male; Propranolol | 1976 |
[Combined treatment of Parkinsonism with L-dopa and peripheral dopa decarboxylase inhibitors--clinical course of 13 cases and levels of serum/dopa and dopamine].
Topics: Adult; Aged; Benserazide; Carbidopa; Dihydroxyphenylalanine; Dopamine; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
[Urinary excretion of 3,4-dihydroxyphenyl-alanine, 3-O-methyldopa, dopamine and homovanillic acid in man. Effects of an inhibitor of decarboxylase of aromatic amino acids (Benserazide) (author's transl)].
Topics: Adult; Benserazide; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Humans; Hydrazines; Male; Methyldopa; Phenylacetates; Time Factors | 1976 |
The effect of L-dopa and an inhibitor of peripheral decarboxylation on glucose metabolism in brain.
Topics: Amino Acids; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Glucose; Brain; Brain Chemistry; Drug Interactions; Glucose; Hydrazines; Levodopa; Rats | 1976 |
[5 years of experience in the treatment of parkinsonism with L-dopa and its combination with Ro4-4602].
Topics: Adult; Aged; Benserazide; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
A histochemical study on the central effect of monoamine precursors.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Brain Chemistry; Capillaries; Cerebral Ventricles; Dopamine; Drug Combinations; Hydrazines; Levodopa; Male; Median Eminence; Norepinephrine; Rats; Serotonin; Substantia Nigra | 1975 |
Inhibition of firing of raphe neurones by tryptophan and 5-hydroxytryptophan: blockade by inhibiting serotonin synthesis with Ro-4-4602.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Depression, Chemical; Hydrazines; Iontophoresis; Lysergic Acid Diethylamide; Male; Mesencephalon; Nervous System; Neural Pathways; Neurons; Rats; Serotonin; Serotonin Antagonists; Time Factors; Tryptophan | 1976 |
An unexpected effect of L-5 hydroxytryptophan-ethyl-ester combined with a peripheral decarboxylase inhibitor on human serum prolactin.
Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carboxy-Lyases; Drug Therapy, Combination; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Infusions, Parenteral; Male; Middle Aged; Prolactin; Serotonin | 1976 |
Letter: Levodopa and dopadecarboxylase in treatment of postural hypotension.
Topics: Aged; Benserazide; Blood Pressure; Cerebrovascular Circulation; Dopa Decarboxylase; Drug Combinations; Humans; Hydrazines; Hypotension, Orthostatic; Levodopa; Male | 1975 |
Abnormal involuntary movements in relation to anticholinergics and levodopa therapy.
Topics: Benserazide; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Movement Disorders; Parasympatholytics; Parkinson Disease | 1975 |
[Experimental exophthalmos. Preliminary communication].
Topics: Animals; Benserazide; Exophthalmos; Female; Guanethidine; Hydrazines; Male; Mice; Pyrogallol; Rats; Thyrotropin; Time Factors | 1975 |
Reduction of hypoxia-induced disturbances by previous treatment with benserazide and L-dopa in rats.
Topics: Animals; Benserazide; Brain Chemistry; Carbon Dioxide; Cerebrovascular Circulation; Dopamine; Female; Hydrazines; Hypoxia; Levodopa; Motor Activity; Norepinephrine; Oxygen; Rats | 1975 |
Urinary excretion of monoamines and their metabolites in patients with Parkinson's disease. Response to long-term treatment with levodopa alone or in combination with a dopa decarboxylase inhibitor and clinical correlations.
Topics: 3,4-Dihydroxyphenylacetic Acid; Benserazide; Biogenic Amines; Dopamine; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Male; Metanephrine; Middle Aged; Normetanephrine; Parkinson Disease; Tyramine; Vanilmandelic Acid | 1975 |
Effect of peripheral decarboxylase inhibition on HVA and 5HIAA in cerebrospinal fluid of depressed patients.
Topics: Adult; Aged; Benserazide; Depression; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Male; Middle Aged; Phenylacetates | 1975 |
Liver function and gastric acid secretion in parkinsonian patients under prolonged treatment with L-dopa and a peripheral decarboxylase inhibitor.
Topics: Aged; Benserazide; Biopsy; Drug Combinations; Gastric Juice; Humans; Hydrazines; Levodopa; Liver; Liver Function Tests; Male; Middle Aged | 1976 |
Preserved striatal tyrosine hydroxylase activity, assessed in vivo, following neonatal hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Benzazepines; Brain Ischemia; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Hydrazines; Hypoxia; Kinetics; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Spiperone; Tyrosine 3-Monooxygenase | 1991 |
Inhibition of tyrosine-3-monooxygenase by benserazide.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Cattle; Corpus Striatum; Dihydroxyphenylalanine; Hydrazines; Rats; Tyrosine 3-Monooxygenase | 1990 |
Severity of Parkinson's disease is a risk factor for peak-dose dyskinesia.
Topics: Aged; Antiparkinson Agents; Benserazide; Carbidopa; Carboxy-Lyases; Dose-Response Relationship, Drug; Drug Combinations; Dyskinesia, Drug-Induced; Humans; Hydrazines; Levodopa; Middle Aged; Motor Skills; Neurologic Examination; Parkinson Disease | 1990 |
Biosynthesis of salsolinol, a tetrahydroisoquinoline alkaloid, in healthy subjects.
Topics: Adult; Benserazide; Dopamine; Drug Combinations; Female; Humans; Hydrazines; Isoquinolines; Levodopa; Male; Stereoisomerism | 1990 |
In vivo voltammetry in the B3 group of serotonin neurons of the rat medulla oblongata after drug-induced modifications of arterial pressure.
Topics: Allopurinol; Animals; Benserazide; Blood Pressure; Electric Stimulation; Hydrazines; Hydroxyindoleacetic Acid; Male; Medulla Oblongata; Neurons; Pargyline; Phenylephrine; Rats; Rats, Inbred Strains; Reference Values; Serotonin | 1988 |
The effect of R-(-)-deprenyl in de novo parkinsonian patients pretreated with levodopa and decarboxylase inhibitor correlated to depression and MHPG, HIAA and HVA levels in the cerebrospinal fluid.
Topics: Benserazide; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Glycols; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Middle Aged; Motor Activity; Parkinson Disease; Phenethylamines; Selegiline | 1989 |
Inhibition of brain dopa-decarboxylase by RO 4-4602 infused ICV blocks alcohol drinking induced in rats by cyanamide.
Topics: Alcohol Drinking; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Body Weight; Brain; Cyanamide; Cyanides; Drinking; Eating; Hydrazines; Injections, Intraventricular; Injections, Subcutaneous; Male; Rats; Rats, Inbred Strains | 1989 |
Treatment of early Parkinson's disease with controlled-release levodopa preparations.
Topics: Aged; Antiparkinson Agents; Benserazide; Carbidopa; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Parkinson Disease | 1989 |
Enantiomeric composition of urinary salsolinol in parkinsonian patients after Madopar.
Topics: Aged; Aged, 80 and over; Benserazide; Drug Combinations; Female; Humans; Hydrazines; Isoquinolines; Levodopa; Male; Middle Aged; Parkinson Disease; Stereoisomerism | 1989 |
[The concentration of homovanillic acid and leucine-enkephalin in the lumbar CSF of patients with Parkinson's disease before and after madopar treatment].
Topics: Adult; Aged; Benserazide; Carboxy-Lyases; Drug Combinations; Enkephalin, Leucine; Female; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1989 |
Madopar HBS and the decompensated phase of Parkinson disease.
Topics: Adult; Aged; Benserazide; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease, Secondary | 1989 |
Treatment of drug-induced exogenous psychosis in parkinsonism with clozapine and fluperlapine.
Topics: Aged; Antipsychotic Agents; Benserazide; Bromocriptine; Clozapine; Delusions; Dibenzazepines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hallucinations; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Psychoses, Substance-Induced; Tryptophan | 1985 |
Effect of benserazid and 6-hydroxydopamine on the development of the last larval instar of the house cricket, Acheta domestica L.
Topics: Animals; Benserazide; Ecdysone; Gryllidae; Hydrazines; Hydroxydopamines; Larva; Neurons; Orthoptera; Oxidopamine | 1986 |
Optimization of symptomatic therapy in Parkinson's disease.
Topics: Benserazide; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Computer-Assisted; Humans; Hydrazines; Levodopa; Models, Biological; Parkinson Disease; Reaction Time; Therapy, Computer-Assisted | 1989 |
[An open study of a new formulation of the levodopa and benserazide combination in the treatment of fluctuations of motor performance in patients with Parkinson's disease].
Topics: Aged; Benserazide; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1988 |
MPTP: clinical implications.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Basal Ganglia; Benserazide; Drug Combinations; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease; Phenethylamines; Pyridines; Selegiline | 1986 |
Parkinson's disease in the elderly: a long-term efficacy study of levodopa/benserazide combination therapy.
Topics: Aged; Aged, 80 and over; Benserazide; Bromocriptine; Confusion; Drug Combinations; Dyskinesia, Drug-Induced; Female; Humans; Hydrazines; Levodopa; Long-Term Care; Male; Middle Aged; Parkinson Disease | 1986 |
Effect of (-)deprenyl in long-term treatment of Parkinson's disease. A 10-years experience.
Topics: Benserazide; Drug Combinations; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease; Phenethylamines; Retrospective Studies; Selegiline; Time Factors | 1986 |
(-)Deprenyl in the treatment of decompensated Parkinson's disease.
Topics: Benserazide; Drug Combinations; Humans; Hydrazines; Levodopa; Movement Disorders; Parkinson Disease; Phenethylamines; Selegiline | 1986 |
Inhibition of decarboxylase and levels of dopa and 3-O-methyldopa: a comparative study of benserazide versus carbidopa in rodents and of Madopar standard versus Madopar HBS in volunteers.
Topics: Administration, Oral; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Brain; Carbidopa; Delayed-Action Preparations; Dihydroxyphenylalanine; Dogs; Dopa Decarboxylase; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrazines; Kidney; Levodopa; Liver; Male; Mice; Rats; Time Factors; Tyrosine | 1987 |
A comparison of the discriminative stimulus properties of l-5-hydroxytryptophan in the presence of either citalopram or Ro 4-4602.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Citalopram; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Hydrazines; Male; Rats; Rats, Inbred F344 | 1988 |
L-5-hydroxytryptophan alone and in combination with a peripheral decarboxylase inhibitor in the treatment of depression.
Topics: 5-Hydroxytryptophan; Adult; Aged; Benserazide; Bipolar Disorder; Depressive Disorder; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Psychological Tests; Retrospective Studies | 1988 |
Madopar HBS in Parkinson patients with nocturnal akinesia.
Topics: Adult; Aged; Benserazide; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Time Factors | 1988 |
Madopar HBS. International workshop on the 'on-off-phenomenon in Parkinson's disease. New possibilities for its management. Agno, November 14-16, 1985.
Topics: Benserazide; Drug Combinations; Humans; Hydrazines; Levodopa; Parkinson Disease | 1987 |
Madopar HBS in the long-term treatment of parkinsonian patients with fluctuations in disability.
Topics: Aged; Benserazide; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Time Factors | 1987 |
A sustained-release formulation of L-dopa (Madopar HBS) in the treatment of nocturnal and early-morning disabilities in Parkinson's disease.
Topics: Benserazide; Circadian Rhythm; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Single-dose pharmacokinetics of Madopar HBS in patients and effect of food and antacid on the absorption of Madopar HBS in volunteers.
Topics: Adult; Antacids; Benserazide; Biological Availability; Delayed-Action Preparations; Drug Combinations; Eating; Gastric Mucosa; Humans; Hydrazines; Levodopa; Middle Aged; Stomach; Tyrosine | 1987 |
Bioavailability of L-dopa after Madopar HBS administration in healthy volunteers.
Topics: Administration, Oral; Adult; Benserazide; Biological Availability; Capsules; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrazines; Levodopa; Male; Middle Aged | 1987 |
Substitution of standard Madopar by Madopar HBS in parkinsonians with fluctuations.
Topics: Aged; Aged, 80 and over; Benserazide; Biological Availability; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Drug Tolerance; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Madopar HBS: slow-release levodopa and benserazide in parkinsonian patients presenting marked fluctuations in symptoms on standard L-dopa treatment.
Topics: Adult; Aged; Benserazide; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Therapeutic value of Madopar HBS: judgment after 2 years experience.
Topics: Adult; Aged; Aged, 80 and over; Benserazide; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Effect of benserazid and allatectomy on the development and structure of the ovariole in the house cricket, Acheta domestica L.
Topics: Animals; Benserazide; Corpora Allata; Female; Gryllidae; Hydrazines; Juvenile Hormones; Microscopy, Electron; Oocytes; Orthoptera | 1986 |
Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: a longterm study.
Topics: Adult; Aged; Benserazide; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Life Expectancy; Longitudinal Studies; Male; Middle Aged; Models, Biological; Phenethylamines; Retrospective Studies; Selegiline | 1985 |
Autonomic cardiovascular responses in parkinsonism: effect of levodopa with dopa-decarboxylase inhibition.
Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Autonomic Nervous System; Benserazide; Blood Pressure; Carbidopa; Drug Therapy, Combination; Female; Heart; Heart Rate; Humans; Hydrazines; Levodopa; Male; Middle Aged; Muscle Contraction; Parkinson Disease | 1985 |
Inhibitory effect of drugs used in the treatment of Parkinson's disease on plasma monoamine oxidase activity.
Topics: Adult; Aged; Benserazide; Benzylamine Oxidase; Carbidopa; Female; Humans; Hydrazines; Isoenzymes; Male; Middle Aged; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Parkinson Disease | 1985 |
Benserazide effects on growth hormone, prolactin, and thyrotropin in normal and acromegalic man.
Topics: Acromegaly; Adult; Benserazide; Dopamine; Female; Growth Hormone; Humans; Hydrazines; Male; Middle Aged; Prolactin; Thyrotropin | 1985 |
Genetic toxicity of several antihypertensive drugs possessing a hydrazine group.
Topics: Animals; Antihypertensive Agents; Benserazide; Carbidopa; Hydralazine; Hydrazines; Male; Mutagens; Rats; Rats, Inbred ACI | 1985 |
Dopaminergic drugs improve human visual contrast sensitivity.
Topics: Adult; Benserazide; Form Perception; Humans; Hydrazines; Levodopa; Nomifensine; Pattern Recognition, Visual | 1985 |
[Clinical significance of cramps of the lower extremities in patients with parkinsonism].
Topics: Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Leg; Levodopa; Male; Middle Aged; Muscle Cramp; Parkinson Disease | 1985 |
Blood-brain barrier to carbidopa (MK-486) and Ro 4-4602, peripheral dopa decarboxylase inhibitors.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood-Brain Barrier; Carbidopa; Carbon Isotopes; Chromatography, Paper; Hydrazines; Oils; Permeability; Tritium; Water | 1973 |
Dose-dependent potentiation or inhibition by Ro4-4602 of 5-HTP hyperthermia in rabbits.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Body Temperature; Body Temperature Regulation; Cerebral Ventricles; Depression, Chemical; Dose-Response Relationship, Drug; Drug Synergism; Hydrazines; Hypothalamus; Rabbits | 1974 |
Inhibition of a minor pathway of L-dopa metabolism in the intestinal lumen using a decarboxylase inhibitor (Ro 4-4602).
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Catechols; Chromatography, Gas; Decarboxylation; Dihydroxyphenylalanine; Hydrazines; Hydroxylation; Intestinal Mucosa; Intestines; Male; Phenylacetates; Rats | 1974 |
Dopamine, noradrenaline and 5-hydroxy-trytamine in relation to motor activity, fighting and mounting behaviour. II. L-dopa and DL-threo-dihydroxyphenylserine in combination with Ro 4-4602 and parachlorophenylalanine.
Topics: Aggression; Animals; Benserazide; Brain; Catechols; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Fenclonine; Humans; Hydrazines; Male; Mice; Mice, Inbred Strains; Motor Activity; Norepinephrine; Rats; Serine; Serotonin; Sexual Behavior, Animal; Sleep | 1973 |
Interactions between amphetamine and serotonergic agents on cat's isolated cerebral cortex.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain Chemistry; Cats; Cerebral Cortex; Cyproheptadine; Dextroamphetamine; Electroencephalography; Female; Fenclonine; Hydrazines; Male; Phentolamine; Serotonin | 1973 |
A serotonergic system involved in the grooming behavior of cats with pontile lesion.
Topics: Animals; Behavior, Animal; Benserazide; Carboxy-Lyases; Cats; Dihydroxyphenylalanine; Dopamine; Feeding Behavior; Fenclonine; Grooming; Hydrazines; Male; Pons; Tryptophan Hydroxylase | 1974 |
Aterial blood pressure in dogs: effects of m-tyrosine alone or in combination with inhibitors of aromatic amino acid decarboxylase; relative hypotensive potencies of L-dopa, DL-m-tyrosine, and L-m-tyrosine.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Pressure; Carbidopa; Dihydroxyphenylalanine; Dogs; Female; Heart Rate; Hydrazines; Male; Tyrosine | 1974 |
[Decarboxylase inhibitors combined with L-dopa in the treatment of Parkinson's disease].
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Benzyl Compounds; Carbidopa; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease; Phenols | 1974 |
[Treatment of Parkinson's syndrome with L-dopa and a decarboxylase inhibitor].
Topics: Adult; Aged; Benserazide; Capsules; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Combinations; Drug Evaluation; Drug Synergism; Enzyme Inhibitors; Female; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease | 1974 |
[Action of a peripheral inhibitor of dopa-decarboxylase on the inhibition by L-DOPA of the hypothalamo-hypophyseo-adrenocortical system in man].
Topics: Adolescent; Adrenal Cortex; Adrenal Glands; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Female; Humans; Hydrazines; Hydrocortisone; Hypothalamo-Hypophyseal System; Levodopa; Male; Middle Aged; Pituitary-Adrenal Function Tests | 1974 |
[Variation in the pharmacologic affects of decarboxylase inhibitor in variable doses in man].
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood-Brain Barrier; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease, Secondary; Time Factors | 1974 |
[The association of L-DOPA and Ro 4-4602 in the treatment of Parkinson's disease (author's transl)].
Topics: Benserazide; Drug Combinations; Drug Evaluation; Humans; Hydrazines; Levodopa; Parkinson Disease | 1974 |
[Psychological changes in parkinsonian patients during L-DOPA, amantidine, and L-DOPA + IDC treatment (author's transl)].
Topics: Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Mental Processes; Parkinson Disease; Psychological Tests | 1974 |
5-Hydroxytryptophan reversal of reserpine enhancement of audiogenic seizure susceptibility in mice.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain; Brain Chemistry; Dopamine; Female; Hydrazines; Male; Mice; Mice, Inbred DBA; Norepinephrine; Reserpine; Seizures; Serotonin; Stimulation, Chemical | 1973 |
The action L-dopa on sexual behaviour of male rats.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain; Catecholamines; Dihydroxyphenylalanine; Hydrazines; Male; Rats; Serotonin; Sexual Behavior, Animal | 1973 |
Skeletal changes induced by dopa decarboxylase inhibitor in rats.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Bone and Bones; Calcium; Femur; Hydrazines; Knee Joint; Magnesium; Male; Phosphorus; Rats; Spine | 1973 |
Action of probenecid on the central nervous system of the rabbit. II. Potentiation of 5-hydroxytryptophan-induced hyperthermia and suppression of this effect by a decarboxylase inhibitor (Ro4-4602).
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Body Temperature; Brain Chemistry; Brain Stem; Drug Synergism; Hydrazines; Hydroxyindoleacetic Acid; Hypothalamus; Male; Probenecid; Rabbits; Serotonin | 1974 |
Effect of a decarboxylase inhibitor (Ro 4-4602) on 5-HTP induced muricide blockade in rats.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Benserazide; Dose-Response Relationship, Drug; Humans; Hydrazines; Injections, Intraperitoneal; Male; Mice; Rats; Time Factors | 1974 |
Effects of a decarboxylase inhibitor on the Dopa and 5-HTP induced changes in the locomotor-like discharge pattern of rabbit hind limb nerves.
Topics: 5-Hydroxytryptophan; Action Potentials; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Dihydroxyphenylalanine; Dopamine; Drug Antagonism; Drug Synergism; Enzyme Inhibitors; Hindlimb; Hydrazines; Locomotion; Male; Neurophysiology; Norepinephrine; Rabbits; Serotonin | 1974 |
[Quantitative rigor determination in Parkinson's disease. Myo-integration for therapy control of L-Dopa in combination with a decarboxylase inhibitor (Ro 8-0576)].
Topics: Aged; Benserazide; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Evaluation; Electromyography; Humans; Hydrazines; Middle Aged; Muscle Rigidity; Muscle Tonus; Parkinson Disease; Stereotaxic Techniques | 1974 |
L-DOPA: centrally mediated emission of seminal fluid in male rats.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Atropine; Benserazide; Carbidopa; Cyproheptadine; Dihydroxyphenylalanine; Dopamine; Ejaculation; Haloperidol; Hydrazines; Hypophysectomy; Lysergic Acid Diethylamide; Male; Melatonin; Methysergide; Norepinephrine; Phentolamine; Propranolol; Rats; Semen; Serotonin | 1972 |
[Treatment of parkinsonism with L-dopa and an L-aromatic amino acid inhibitor].
Topics: Benserazide; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Combinations; Humans; Hydrazines; Parkinson Disease; Time Factors | 1972 |
[Treatment of Parkinson's syndrome with L-dopa and its methylated derivatives: 3-OMD and 4-OMD associated with a decarboxylase inhibitor. Clinical and biochemical study].
Topics: Aged; Benserazide; Carboxy-Lyases; Depression; Dihydroxyphenylalanine; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrazines; Methyldopa; Middle Aged; Paralysis; Parkinson Disease; Sleep Wake Disorders; Time Factors | 1973 |
Plasma concentration of levodopa in patients with Parkinson's disease.
Topics: Administration, Oral; Adult; Aged; Benserazide; Dihydroxyphenylalanine; Drug Combinations; Female; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease; Parkinson Disease, Postencephalitic | 1973 |
[Dopaminergic control of the diencephalo-pituitary axis for somatotropin secretion].
Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Diencephalon; Dihydroxyphenylalanine; Drug Combinations; Female; Growth Hormone; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease; Pituitary Gland | 1973 |
Bensarazid with L-dopa in the treatment of parkinson's disease.
Topics: Adult; Aged; Benserazide; Dihydroxyphenylalanine; Drug Therapy, Combination; Female; Humans; Hydrazines; L-Lactate Dehydrogenase; Male; Middle Aged; Parkinson Disease; Urea | 1974 |
[Relationship between the antihypertensive activity of methyldopa and the appearance of its metabolites in the heart and brain of the hypertensive rat].
Topics: Animals; Antihypertensive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Biotransformation; Blood Pressure; Brain; Disulfides; Disulfiram; Dopamine; Dopamine beta-Hydroxylase; Hydrazines; Hypertension; Imidazoles; Male; Methane; Methyldopa; Myocardium; Norepinephrine; Rats; Sympatholytics; Time Factors; Tritium | 1974 |
The role of brain 5-hydroxytryptamine in the central action of L-DOPA.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Body Temperature; Brain; Brain Chemistry; Depression, Chemical; Dihydroxyphenylalanine; Female; Hydrazines; Hydroxyindoleacetic Acid; Locomotion; Lysergic Acid Diethylamide; Rats; Serotonin; Stimulation, Chemical; Time Factors | 1974 |
Pharmacokinetics of the decarboxylase inhibitor benserazide in man; its tissue distribution in the rat.
Topics: Aged; Animals; Autoradiography; Benserazide; Brain; Carbon Radioisotopes; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Stability; Feces; Female; Gastric Juice; Humans; Hydrazines; Intestinal Absorption; Kidney; Liver; Male; Middle Aged; Myocardium; Parkinson Disease; Rats; Time Factors | 1974 |
[L-DOPA-and dopa-decarboxylase inhibitor combination for the treatment of Parkinsonism].
Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Dihydroxyphenylalanine; Drug Therapy, Combination; Female; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease | 1974 |
Adverse clinical side effects of levodopa therapy.
Topics: Antiparkinson Agents; Arrhythmias, Cardiac; Benserazide; Carboxy-Lyases; Dihydroxyphenylalanine; Edema; Endocrine System Diseases; Feeding and Eating Disorders; Hematopoiesis; Humans; Hydrazines; Libido; Movement Disorders; Myocardial Infarction; Nausea; Neurologic Manifestations; Respiration; Time Factors; Uric Acid; Urination Disorders; Vomiting | 1971 |
Dopamine agonists in clinical research for new tardive dyskinesia treatments.
Topics: Adult; Aged; Antipsychotic Agents; Apomorphine; Benserazide; Carbidopa; Dopamine; Drug Combinations; Dyskinesia, Drug-Induced; Humans; Hydrazines; Levodopa; Middle Aged; Synaptic Transmission | 1983 |
In vivo and in vitro evidence of dopaminergic system down regulation induced by chronic L-DOPA.
Topics: Animals; Apomorphine; Benserazide; Binding Sites; Cell Membrane; Corpus Striatum; Dopamine; Hydrazines; Levodopa; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Tetrahydronaphthalenes; Tyrosine 3-Monooxygenase | 1984 |
Postanoxic myoclonus. Treatment of a case with 5-hydroxytryptophane and a decarboxylase inhibitor.
Topics: 5-Hydroxytryptophan; Benserazide; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Male; Middle Aged; Myoclonus | 1981 |
Differential pulse voltammetry in brain tissue. II. Detection of 5-hydroxyindoleacetic acid in the rat striatum.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Benzyl Alcohols; Clorgyline; Corpus Striatum; Fenclonine; Hydrazines; Hydroxyindoleacetic Acid; Male; Potentiometry; Probenecid; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Tryptophan | 1981 |
Human pharmacokinetics of long term 5-hydroxytryptophan combined with decarboxylase inhibitors.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Platelets; Carbidopa; Drug Interactions; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Kinetics; Male; Middle Aged; Protein Binding | 1982 |
Differential pulse voltammetry in the dorsal horn of the spinal cord of the anesthetized rat: are the voltammograms related to 5-HT and/or to 5-HIAA?
Topics: Animals; Benserazide; Clorgyline; Dose-Response Relationship, Drug; Electric Conductivity; Hydrazines; Hydroxyindoleacetic Acid; Male; Microelectrodes; Probenecid; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Spinal Cord | 1983 |
Regression of cerebellar syndrome with long-term administration of 5-HTP or the combination 5-HTP-benserazide.
Topics: 5-Hydroxytryptophan; Benserazide; Cerebellar Ataxia; Dopamine; Drug Therapy, Combination; Friedreich Ataxia; Humans; Hydrazines; Olivary Nucleus; Pons; Serotonin; Syndrome | 1984 |
[Combined (surgical and drug) therapy of parkinsonism].
Topics: Benserazide; Catecholamines; Combined Modality Therapy; Diencephalon; Drug Combinations; Humans; Hydrazines; Levodopa; Parkinson Disease; Stereotaxic Techniques | 1984 |
The effect of l-DOPA and benserazide on the amount of dopamine in the corpus striatum of X-irradiated rats.
Topics: Animals; Benserazide; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Hydrazines; Male; Rats; Rats, Inbred Strains | 1983 |
Effects of benserazide, carbidopa and isoniazid administration on tryptophan-nicotinamide nucleotide metabolism in the rat.
Topics: Animals; Benserazide; Body Weight; Carbidopa; Diet; Hydrazines; Isoniazid; Liver; Male; Niacinamide; Rats; Ribonucleotides; Time Factors; Tryptophan | 1980 |
Mechanisms involved in the prolactin-releasing effect of benserazide.
Topics: Animals; Benserazide; Binding, Competitive; Dopamine; Female; Hydrazines; In Vitro Techniques; Levodopa; Male; Median Eminence; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone | 1984 |
Combined use of benserazide and carbidopa in Parkinson's disease.
Topics: Adult; Aged; Benserazide; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Outcome and Process Assessment, Health Care; Parkinson Disease | 1984 |
Day-night differences in estimated rates of 5-hydroxytryptamine turnover in the rat pineal gland.
Topics: Animals; Benserazide; Circadian Rhythm; Hydrazines; Male; Pargyline; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Differential effect of benserazide on catecholamine concentrations in the rat pineal, cerebral cortex and hypothalamus.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain Chemistry; Catecholamines; Cerebral Cortex; Dopamine; Hydrazines; Hypothalamus; Norepinephrine; Pineal Gland; Rats; Rats, Inbred Strains | 1983 |
Response to Sinemet 25/100 in Parkinson's disease.
Topics: Aged; Benserazide; Body Weight; Carbidopa; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Sex Factors | 1984 |
Pineal aryl acylamidase: effects of melatonin, serotonin-related compounds, beta-carbolines, RO4-4602 and antidepressants.
Topics: Amidohydrolases; Animals; Antidepressive Agents; Benserazide; Carbolines; Hydrazines; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Kinetics; Male; Melatonin; Pineal Gland; Proteins; Rats; Rats, Inbred Strains; Serotonin | 1984 |
[Treatment of patients with vascular parkinsonism with the preparations nakom and madopar].
Topics: Adult; Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Combinations; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease, Secondary | 1984 |
The effect of L-tryptophan on motor activity and its prevention by an extracerebral decarboxylase inhibitor and by 5-HT receptor blockers.
Topics: Animals; Benserazide; Brain; Hydrazines; Male; Motor Activity; Rats; Serotonin; Serotonin Antagonists; Tryptophan | 1980 |
[Madopar in the treatment of paralysis agitans: II. TRH activation test, EMG examination and HVA level in cerebrospinal fluid before and after treatment].
Topics: Aged; Benserazide; Drug Combinations; Electromyography; Female; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Thyrotropin; Thyrotropin-Releasing Hormone | 1980 |
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans; Hydrazines; Middle Aged; Parkinson Disease; Schizophrenia; Tryptophan | 1982 |
Improved control of brittle Parkinsonism by separate administration of levodopa and benserazide.
Topics: Benserazide; Drug Administration Schedule; Female; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease; Time Factors | 1982 |
Thyrotrophin and prolactin responses to thyrotrophin-releasing hormone in patients with Parkinson's disease.
Topics: Adult; Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine | 1982 |
The effect of some decarboxylase inhibitors on striatal tyramines in the mouse.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Carboxy-Lyases; Corpus Striatum; Hydrazines; Isomerism; Male; Mice; Tyramine | 1983 |
Effect of benserazide on the levels of pineal 5-hydroxytryptamine, melatonin synthesising enzymes and serum melatonin.
Topics: Acetylserotonin O-Methyltransferase; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Arylamine N-Acetyltransferase; Benserazide; Circadian Rhythm; Hydrazines; Light; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Serotonin | 1982 |
Blockade of 5-HTp reduction of ethanol drinking with the decarboxylase inhibitor, ro 4-4602.
Topics: 5-Hydroxytryptophan; Alcohol Drinking; Animals; Benserazide; Dose-Response Relationship, Drug; Hydrazines; Premedication; Rats; Rats, Inbred Strains | 1981 |
[Regression of the cerebellar syndrome under long-term administration of 5-HTP or the combination of 5-HTP and benserazide. 26 cases quantified and treated using computer methods].
Topics: 5-Hydroxytryptophan; Benserazide; Cerebellar Ataxia; Computers; Drug Therapy, Combination; Humans; Hydrazines; Kinetics; Time Factors | 1982 |
A glimpse into Roche research: antiparkinson treatment.
Topics: Antiparkinson Agents; Benserazide; Drug Combinations; Drug Industry; History, 20th Century; Humans; Hydrazines; Levodopa; Male; Switzerland | 1982 |
Prolactin response to acute administration of different L-dopa plus decarboxylase inhibitors in Parkinson's disease.
Topics: Aged; Animals; Benserazide; Carbidopa; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Prolactin; Rats | 1982 |
Characteristics and specificity of phenelzine and benserazide as inhibitors of benzylamine oxidase and monoamine oxidase.
Topics: Animals; Benserazide; Benzylamine Oxidase; Hydrazines; Kinetics; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenelzine; Rats; Rats, Inbred Strains | 1982 |
Acute non-haemolytic anemia after short administration of L Dopa plus Benserazide.
Topics: Acute Disease; Aged; Anemia; Antiparkinson Agents; Benserazide; Humans; Hydrazines; Levodopa; Male | 1982 |
In vitro and in vivo inhibition by benserazide of clorgyline-resistant amine oxidases in rat cardiovascular tissues.
Topics: Amine Oxidase (Copper-Containing); Animals; Benserazide; Cardiovascular System; Clorgyline; Drug Resistance; Hydrazines; In Vitro Techniques; Kinetics; Levodopa; Male; Monoamine Oxidase; Oxidoreductases Acting on CH-NH Group Donors; Propylamines; Rats; Rats, Inbred Strains | 1982 |
Treatment of restless legs syndrome with levodopa plus benserazide.
Topics: Adult; Benserazide; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Restless Legs Syndrome | 1982 |
Benserazide and nomifensine in the diagnosis of prolactin-secreting pituitary adenomas.
Topics: Adenoma; Benserazide; Female; Humans; Hydrazines; Isoquinolines; Nomifensine; Pituitary Neoplasms; Postpartum Period; Pregnancy; Prolactin | 1982 |
Comparative 90-day toxicity of two decarboxylase inhibitors, benserazide and carbidopa, in the rat.
Topics: Animals; Benserazide; Blood; Bone and Bones; Carbidopa; Carboxy-Lyases; Dose-Response Relationship, Drug; Eating; Female; Growth Disorders; Hydrazines; Male; Organ Size; Radiography; Rats; Rats, Inbred Strains | 1982 |
Differential effect of benserazide (Ro4-4602) on the concentration of indoleamines in rat pineal and hypothalamus.
Topics: Animals; Benserazide; Hydrazines; Hypothalamus; Male; Melatonin; Pineal Gland; Rats; Serotonin | 1981 |
L-dopa and benserazide in the treatment of acute hepatic encephalopathy in infancy.
Topics: Acute Disease; Benserazide; Female; Hepatic Encephalopathy; Humans; Hydrazines; Infant; Levodopa | 1980 |
Systemic and in vitro effects of GAD and GABA-T inhibitors on AADC activity and of AADC inhibitors on GAD.
Topics: 4-Aminobutyrate Transaminase; Adrenal Glands; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Benzyl Alcohols; Carbidopa; Carboxy-Lyases; Corpus Striatum; Female; Glutamate Decarboxylase; Hydrazines; Penicillamine; Rats; Transaminases | 1981 |
Effects of benserazide and carbidopa on the metabolism of L-tryptophan by isolated rat liver cells.
Topics: Alanine; Animals; Benserazide; Carbidopa; Chemical Phenomena; Chemistry; Hydrazines; Hydrolases; Liver; Oxidation-Reduction; Pyruvates; Rats; Tryptophan; Tryptophan Oxygenase | 1981 |
Benserazide, a stimulator of prolactin release: a new test in the diagnosis of pituitary prolactin-secreting tumours.
Topics: Adenoma; Adult; Benserazide; Brain; Diagnosis, Differential; Female; Humans; Hydrazines; Pituitary Neoplasms; Prolactin; Tomography, X-Ray Computed | 1981 |
Growth hormone and prolactin stimulation by Madopar in Parkinson's disease.
Topics: Adult; Aged; Antiparkinson Agents; Benserazide; Drug Combinations; Female; Growth Hormone; Humans; Hydrazines; Levodopa; Lisuride; Male; Middle Aged; Parkinson Disease; Prolactin; Receptors, Dopamine | 1981 |
The influence of benserazide on changes in monoamine oxidase activity in some rat tissues following treatment with L-DOPA.
Topics: Animals; Benserazide; Benzylamines; Growth; Hydrazines; Kidney; Kinetics; Levodopa; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Myocardium; Rats; Rats, Inbred Strains; Serotonin | 1980 |
Dose and sex related effects of aromatic aminoacids decarboxylase inhibitors on serum prolactin in humans.
Topics: Administration, Oral; Adult; Age Factors; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Dose-Response Relationship, Drug; Female; Humans; Hydrazines; Male; Prolactin; Sex Factors | 1980 |
TSH and prolactin stimulation by the decarboxylase inhibitor benserazide in primary hypothyroidism.
Topics: Adult; Benserazide; Female; Humans; Hydrazines; Hypothyroidism; Male; Middle Aged; Prolactin; Secretory Rate; Stimulation, Chemical; Thyrotropin | 1980 |
[Madopar in the treatment of paralysis agitans. I. Therapeutic efficacy and side-effects in 56 cases (author's transl)].
Topics: Adult; Benserazide; Electrocardiography; Female; Humans; Hydrazines; Hyperkinesis; Levodopa; Male; Mental Disorders; Middle Aged; Parkinson Disease | 1980 |
Benserazide and carbidopa as substrates of catechol-O-methyltransferase: new mechanism of action in Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Benzyl Compounds; Carbidopa; Catechol O-Methyltransferase; Hydrazines; Kinetics; Liver; Parkinson Disease; S-Adenosylmethionine; Substrate Specificity; Swine | 1980 |
Pituitary hormone secretion after inhibition of L-aromatic amino acid decarboxylase activity in man.
Topics: Adult; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Benzimidazoles; Blood-Brain Barrier; Domperidone; Female; Gonadotropins, Pituitary; Humans; Hydrazines; Male; Middle Aged; Piperidines; Pituitary Hormones; Prolactin; Receptors, Dopamine; Thyrotropin | 1980 |
Microdialysis monitoring of 3,4-dihydroxyphenylalanine accumulation after decarboxylase inhibition: a means to estimate in vivo changes in tyrosine hydroxylase activity of the rat locus ceruleus.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Chromatography, High Pressure Liquid; Dialysis; Dihydroxyphenylalanine; Hydrazines; Kinetics; Locus Coeruleus; Male; Methyltyrosines; Microchemistry; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase | 1993 |
L-3,4-dihydroxyphenylalanine-induced c-Fos expression in the CNS under inhibition of central aromatic L-amino acid decarboxylase.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Cell Count; Central Nervous System; Dopamine Agents; Drug Interactions; Enzyme Inhibitors; Functional Laterality; Gene Expression Regulation; Hydrazines; Immunohistochemistry; Levodopa; Male; Medial Forebrain Bundle; Motor Activity; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 2006 |
Locomotor response to L-DOPA in reserpine-treated rats following central inhibition of aromatic L-amino acid decarboxylase: further evidence for non-dopaminergic actions of L-DOPA and its metabolites.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Brain Chemistry; Disease Models, Animal; Dopamine Agents; Drug Combinations; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Hydrazines; Hyperkinesis; Levodopa; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reserpine; Serotonin Receptor Agonists | 2010 |
Yokukansan, a Traditional Japanese Medicine, Enhances the L-DOPA-Induced Rotational Response in 6-Hydroxydopamine-Lesioned Rats: Possible Inhibition of COMT.
Topics: Animals; Benserazide; Catechols; Cell Line; Corpus Striatum; Dopamine; Drugs, Chinese Herbal; Hydrazines; Levodopa; Male; Medicine, East Asian Traditional; Nitriles; Oxidopamine; Pargyline; Rats; Rats, Wistar | 2016 |
Neuroprotective effects of stemazole in the MPTP-induced acute model of Parkinson's disease: Involvement of the dopamine system.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benserazide; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Combinations; Hydrazines; Levodopa; Male; Mice, Inbred C57BL; Motor Activity; Neuroprotective Agents; Oxadiazoles; Oxidative Stress; Parkinson Disease; Substantia Nigra; Tyrosine 3-Monooxygenase | 2016 |